ATE442856T1 - Immunmodulatorische konstruktionen und ihre verwendung - Google Patents

Immunmodulatorische konstruktionen und ihre verwendung

Info

Publication number: ATE442856T1
Authority: AT; Austria
Prior art keywords: immunomodulator; immunomodulatory; apc; disorder; therapeutic
Prior art date: 2000-12-04

Application number

AT01999384T

Other languages

English (en)

Inventor

John David Fraser

Melissa Nicholson

Original Assignee

Auckland Uniservices Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-12-04

Filing date

2001-12-04

Publication date

2009-10-15

2001-12-04 Application filed by Auckland Uniservices Ltd filed Critical Auckland Uniservices Ltd

2009-10-15 Application granted granted Critical

2009-10-15 Publication of ATE442856T1 publication Critical patent/ATE442856T1/de

Links

230000002519 immonomodulatory effect Effects 0.000 title abstract 2
239000002955 immunomodulating agent Substances 0.000 abstract 4
230000002584 immunomodulator Effects 0.000 abstract 4
229940121354 immunomodulator Drugs 0.000 abstract 4
210000000612 antigen-presenting cell Anatomy 0.000 abstract 2
238000000034 method Methods 0.000 abstract 2
238000011321 prophylaxis Methods 0.000 abstract 2
230000001225 therapeutic effect Effects 0.000 abstract 2
101000686985 Mouse mammary tumor virus (strain C3H) Protein PR73 Proteins 0.000 abstract 1
108091008874 T cell receptors Proteins 0.000 abstract 1
102000016266 T-Cell Antigen Receptors Human genes 0.000 abstract 1
239000000427 antigen Substances 0.000 abstract 1
102000036639 antigens Human genes 0.000 abstract 1
108091007433 antigens Proteins 0.000 abstract 1
239000003814 drug Substances 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
231100000617 superantigen Toxicity 0.000 abstract 1
230000008685 targeting Effects 0.000 abstract 1
229960005486 vaccine Drugs 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/385—Haptens or antigens, bound to carriers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/09—Lactobacillales, e.g. aerococcus, enterococcus, lactobacillus, lactococcus, streptococcus
- A61K39/092—Streptococcus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/315—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/515—Animal cells
- A61K2039/5154—Antigen presenting cells [APCs], e.g. dendritic cells or macrophages
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
- A61K2039/6031—Proteins
- A61K2039/6068—Other bacterial proteins, e.g. OMP

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Gastroenterology & Hepatology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Mycology (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Virology (AREA)
Pulmonology (AREA)
Transplantation (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

AT01999384T 2000-12-04 2001-12-04 Immunmodulatorische konstruktionen und ihre verwendung ATE442856T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US25124300P	2000-12-04	2000-12-04
PCT/NZ2001/000267 WO2002045739A1 (en)	2000-12-04	2001-12-04	Immunomodulatory constructs and their uses

Publications (1)

Publication Number	Publication Date
ATE442856T1 true ATE442856T1 (de)	2009-10-15

Family

ID=22951085

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01999384T ATE442856T1 (de)	2000-12-04	2001-12-04	Immunmodulatorische konstruktionen und ihre verwendung

Country Status (9)

Country	Link
US (1)	US20030124142A1 (de)
EP (1)	EP1349568B1 (de)
JP (1)	JP2004515479A (de)
AT (1)	ATE442856T1 (de)
AU (2)	AU1648102A (de)
CA (1)	CA2436856A1 (de)
DE (1)	DE60139954D1 (de)
NZ (1)	NZ544579A (de)
WO (1)	WO2002045739A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
TW517061B (en) *	1996-03-29	2003-01-11	Pharmacia & Amp Upjohn Ab	Modified/chimeric superantigens and their use
US7491402B2 (en) *	1998-12-24	2009-02-17	Auckland Uniservices Limited	Superantigens SMEZ-2, SPE-G, SPE-H and SPE-J and uses thereof
SE0102327D0 (sv)	2001-06-28	2001-06-28	Active Biotech Ab	A novel engineered superantigen for human therapy
NZ519371A (en) *	2002-06-04	2004-11-26	Auckland Uniservices Ltd	Immunomodulatory constructs and their uses
KR20250071286A (ko)	2016-01-10	2025-05-21	네오티엑스 테라퓨틱스 엘티디.	면역강화제에 의해 증진되는 초항원 매개된 암 면역요법
CA3139899A1 (en)	2019-05-15	2020-11-19	Neotx Therapeutics Ltd.	Cancer treatment
CN115484978A (zh)	2020-03-05	2022-12-16	尼奥克斯医疗有限公司	使用免疫细胞治疗癌症的方法和组合物
JP2025535082A (ja) *	2022-10-05	2025-10-22	エムユーエスシーファウンデーションフォーリサーチディベロップメント	がんの処置のためのスーパー抗原ワクチンコンジュゲート

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5116964A (en) *	1989-02-23	1992-05-26	Genentech, Inc.	Hybrid immunoglobulins
US6042837A (en) *	1989-09-20	2000-03-28	Kalland; Terje	Methods of staphylococcal enterotoxin directed cell-mediated cytotoxicity (SDCC)
US5728388A (en) *	1989-10-03	1998-03-17	Terman; David S.	Method of cancer treatment
US6126945A (en) *	1989-10-03	2000-10-03	Pharmacia Ab	Tumor killing effects of enterotoxins, superantigens, and related compounds
US6197299B1 (en) *	1990-07-20	2001-03-06	Pharmacia & Upjohn Ab	Antibody conjugates
US5858363A (en) *	1990-07-20	1999-01-12	Pharmacia & Upjohn Ab	Target specific antibody-superantigen conjugates and their preparation
US5545716A (en) *	1992-09-08	1996-08-13	University Of Florida	Superantigen agonist and antagonist peptides
US5519114A (en) *	1993-10-29	1996-05-21	University Of Florida Research Foundation, Inc.	Retroviral superantigens, superantigen peptides, and methods of use
US5698679A (en) *	1994-09-19	1997-12-16	National Jewish Center For Immunology And Respiratory Medicine	Product and process for targeting an immune response
DE19533118C1 (de) *	1995-09-07	1996-11-28	Siemens Ag	Sortiereinrichtung, insbesondere für Postgut
SE9601245D0 (sv) *	1996-03-29	1996-03-29	Pharmacia Ab	Chimeric superantigens and their use
TW517061B (en) *	1996-03-29	2003-01-11	Pharmacia & Amp Upjohn Ab	Modified/chimeric superantigens and their use
CN1148449C (zh) *	1996-12-06	2004-05-05	明尼苏达大学董事会	链球菌毒素c突变体及其使用方法
US6340461B1 (en) *	1996-12-17	2002-01-22	David Stephen Terman	Superantigen based methods and compositions for treatment of diseases

2001
- 2001-12-04 JP JP2002547522A patent/JP2004515479A/ja active Pending
- 2001-12-04 AU AU1648102A patent/AU1648102A/xx active Pending
- 2001-12-04 CA CA002436856A patent/CA2436856A1/en not_active Abandoned
- 2001-12-04 US US10/006,797 patent/US20030124142A1/en not_active Abandoned
- 2001-12-04 AT AT01999384T patent/ATE442856T1/de not_active IP Right Cessation
- 2001-12-04 EP EP01999384A patent/EP1349568B1/de not_active Expired - Lifetime
- 2001-12-04 DE DE60139954T patent/DE60139954D1/de not_active Expired - Lifetime
- 2001-12-04 NZ NZ544579A patent/NZ544579A/en unknown
- 2001-12-04 WO PCT/NZ2001/000267 patent/WO2002045739A1/en not_active Ceased
- 2001-12-04 AU AU2002216481A patent/AU2002216481B2/en not_active Ceased

Also Published As

Publication number	Publication date
JP2004515479A (ja)	2004-05-27
CA2436856A1 (en)	2002-06-13
AU2002216481B2 (en)	2008-05-01
EP1349568A4 (de)	2005-03-30
EP1349568B1 (de)	2009-09-16
US20030124142A1 (en)	2003-07-03
EP1349568A1 (de)	2003-10-08
DE60139954D1 (de)	2009-10-29
WO2002045739A1 (en)	2002-06-13
NZ544579A (en)	2007-12-21
AU1648102A (en)	2002-06-18

Legal Events

Date	Code	Title	Description
2010-03-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

Publication	Publication Date	Title
DK1434603T3 (da)	2010-04-26	Fremgangsmåde til behandling ved anvendelse af ligand-immunogen-konjugater
TR200002855T2 (tr)	2000-12-21	Raloksifenin solunum yolu ile veya burundan uygulanması.
CY1112376T1 (el)	2015-12-09	Παραγωγα 2,3,4,9-τετραϋδρο-1η-καρβαζολης ως ανταγωνιστες του υποδοχεα crth2
NO20062504L (no)	2006-07-21	Sammensetninger og doseringsformer for forbedret absorpsjon
DE69922676D1 (de)	2005-01-20	N-aralkylaminotetraline als neuropeptid-y-y5-rezeptorliganden
ATE269846T1 (de)	2004-07-15	N-substituierte aminotetraline als neuropeptid y y5 rezeptor-liganden und ihre anwendung zur behandlung von fettleibigkeit und anderen erkrankungen
FI20050932A7 (fi)	2005-11-18	Heterobifunktionaaliset polymeeriset biokonjugaatit
NO20031266D0 (no)	2003-03-19	Kondenserte heterocykliske suksinimid-forbindelser og analoger derav, modulatorer for nukle¶r hormonreseptorfunksjon
NO20015073D0 (no)	2001-10-18	Vaksiner
WO2003061578A3 (en)	2003-12-04	Compositions for treatment or prevention of bioterrorism
WO2005097211A3 (en)	2007-03-29	Compositions as adjuvants to improve immune responses to vaccines and methods of use
FR2827605B1 (fr)	2004-07-16	Nouveaux peptides derives de la proteine g du vrs et leur utilisation dans un vaccin
DE60331412D1 (de)	2010-04-08	Hiv-vakzine und anwendungsverfahren
DE60139954D1 (de)	2009-10-29	Immunmodulatorische konstruktionen und ihre verwendung
EP1379508A4 (de)	2005-12-28	N-(aryl)-2-arylethensulfonamide und ihre therapeutischen anwendungen
BR0112807A (pt)	2003-07-01	Derivados de indol e sua aplicação como medicamento
EE200100366A (et)	2002-10-15	Antikehade kasutamine vähivastase farmatseutilisekompositsiooni valmistamiseks
NO995481L (no)	1999-11-09	Glykokonjugater av 20 (S)-camptothecin
WO2005010022A3 (en)	2006-07-06	Agonist polypeptide of receptor for zot and zonulin
CY1107560T1 (el)	2013-03-13	Ζωντανα εξασθενημενα βακτηρια για χρηση σε εμβολιο
MXPA04001912A (es)	2004-07-23	Aminobenzofenonas novedosas.
TR199901385T2 (xx)	1999-11-22	Piperidin t�revleri.
DE602004009470D1 (de)	2007-11-22	Faserreiche fraktion von trigonella-foenum-graecum-samen und verwendung davon als pharmazeutischer exzipient
WO2001024764A3 (en)	2001-08-23	Cell targeting compositions and methods of using the same
ATE261732T1 (de)	2004-04-15	Pharmazeutische zusammensetzung, umfassend eukalyptus- und orangenöl