ATE442865T1 - Dreigeteilte konjugate mit einer struktur, die mit zellmembran-rafts interagieren und ihre verwendung - Google Patents
Dreigeteilte konjugate mit einer struktur, die mit zellmembran-rafts interagieren und ihre verwendungInfo
- Publication number
- ATE442865T1 ATE442865T1 AT05732179T AT05732179T ATE442865T1 AT E442865 T1 ATE442865 T1 AT E442865T1 AT 05732179 T AT05732179 T AT 05732179T AT 05732179 T AT05732179 T AT 05732179T AT E442865 T1 ATE442865 T1 AT E442865T1
- Authority
- AT
- Austria
- Prior art keywords
- moiety
- cell membrane
- membrane rafts
- structure interacting
- part conjugates
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/554—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being a steroid plant sterol, glycyrrhetic acid, enoxolone or bile acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/543—Lipids, e.g. triglycerides; Polyamines, e.g. spermine or spermidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Botany (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Neurology (AREA)
- Oncology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Child & Adolescent Psychology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Neurosurgery (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP04008607 | 2004-04-08 | ||
| US57506804P | 2004-05-27 | 2004-05-27 | |
| US66197605P | 2005-03-11 | 2005-03-11 | |
| PCT/EP2005/003740 WO2005097199A1 (en) | 2004-04-08 | 2005-04-08 | Tripartite conjugates containing a structure interacting with cell membrane rafts and their use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE442865T1 true ATE442865T1 (de) | 2009-10-15 |
Family
ID=34965861
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05732179T ATE442865T1 (de) | 2004-04-08 | 2005-04-08 | Dreigeteilte konjugate mit einer struktur, die mit zellmembran-rafts interagieren und ihre verwendung |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20080317767A1 (de) |
| EP (2) | EP1732612B1 (de) |
| AT (1) | ATE442865T1 (de) |
| AU (1) | AU2005231622B2 (de) |
| CA (1) | CA2562266A1 (de) |
| DE (1) | DE602005016658D1 (de) |
| WO (1) | WO2005097199A1 (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2335705B1 (de) * | 2006-08-04 | 2013-12-18 | MEGMILK SNOW BRAND Co., Ltd. | Verwendung von Sphingomyelin zur Behandlung von Influenza |
| JP5202827B2 (ja) * | 2006-08-04 | 2013-06-05 | 雪印メグミルク株式会社 | 感染予防剤 |
| KR20100015546A (ko) | 2007-04-13 | 2010-02-12 | 사노피-아벤티스 | Ｎ-아미노인돌의 전이 금속 촉매된 합성 |
| GB0720503D0 (en) * | 2007-10-22 | 2007-11-28 | Angeletti P Ist Richerche Bio | New compound |
| WO2010078329A1 (en) * | 2008-12-30 | 2010-07-08 | President And Fellows Of Harvard College | Methods and compositions for the treatment of pathogenic diseases |
| EP2834264A1 (de) * | 2012-04-04 | 2015-02-11 | Yeda Research and Development Co. Ltd. | Lipopeptidkonjugate mit sphingolipid und aus hiv gp41 gewonnenen peptiden |
| WO2015115796A1 (ko) * | 2014-01-29 | 2015-08-06 | 주식회사 휴메딕스 | 페길레이션된 7-디하이드로콜레스테롤 유도체 |
| EP3224272B1 (de) | 2014-11-28 | 2019-08-21 | F.Hoffmann-La Roche Ag | Peptid |
| US10683329B2 (en) | 2014-11-28 | 2020-06-16 | Hoffmann-La Roche Inc. | Dual-site BACE1 inhibitors |
| CN107849092A (zh) * | 2015-07-24 | 2018-03-27 | 豪夫迈·罗氏有限公司 | Bace1抑制剂肽 |
| EA201891472A1 (ru) | 2015-12-22 | 2018-12-28 | Такеда Фармасьютикал Компани Лимитед | Тройные модуляторы эндосомальных рецепторов, сопряженных с g-белком |
| CN109152777A (zh) * | 2016-05-20 | 2019-01-04 | 武田药品工业株式会社 | 疼痛的治疗 |
| US11559568B2 (en) | 2017-10-27 | 2023-01-24 | Children's Medical Center Corporation | Short chain ceramide-based lipids and uses thereof |
| EA202091524A1 (ru) * | 2017-12-20 | 2020-09-16 | Такеда Фармасьютикал Компани Лимитед | Ингибиторы рецептора, активируемого протеазой 2 |
| AU2019252912A1 (en) | 2018-04-12 | 2020-10-22 | The Children's Medical Center Corporation | Ceramide-like lipid-based delivery vehicles and uses thereof |
| US12350381B2 (en) | 2018-11-26 | 2025-07-08 | Arytha Biosciences, Llc | Nanoparticles containing cellular membrane and uses thereof |
| EP4255904A2 (de) | 2020-12-03 | 2023-10-11 | Domain Therapeutics | Par-2-inhibitoren |
| KR102423002B1 (ko) * | 2021-02-17 | 2022-07-21 | 주식회사 엘씨에스바이오텍 | 신규 세라마이드, 그의 제조방법 및 그의 용도 |
| CN119384420A (zh) | 2022-06-03 | 2025-01-28 | 多曼治疗学公司 | 新型par-2抑制剂 |
| WO2025191185A1 (en) | 2024-03-15 | 2025-09-18 | Domain Therapeutics | Azine-based compounds as par-2 inhibitors and therapeutic uses thereof |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR850004274A (ko) * | 1983-12-13 | 1985-07-11 | 원본미기재 | 에리트로포이에틴의 제조방법 |
| US4946778A (en) * | 1987-09-21 | 1990-08-07 | Genex Corporation | Single polypeptide chain binding molecules |
| US5446026A (en) * | 1989-08-09 | 1995-08-29 | Advanced Peptides & Biotechnology Sciences | Potent non-opiate analgesic |
| IT1234909B (it) * | 1989-09-11 | 1992-06-02 | Farina Attilio | Dispositivo di telecomando per ricevitore di televisione atto a cifrare in modo esclusivo i codici di comando e corrispondente circuito decifratore |
| DE3930696A1 (de) * | 1989-09-14 | 1991-03-28 | Hoechst Ag | Gallensaeurederivate, verfahren zu ihrer herstellung, verwendung als arzneimittel |
| US5439899A (en) * | 1993-03-10 | 1995-08-08 | Purdue Research Foundation | Cosalane and related compounds having activity against aids and aids-related infections |
| US5464933A (en) * | 1993-06-07 | 1995-11-07 | Duke University | Synthetic peptide inhibitors of HIV transmission |
| US6258782B1 (en) * | 1998-05-20 | 2001-07-10 | Trimeris, Inc. | Hybrid polypeptides with enhanced pharmacokinetic properties |
| GB2355009A (en) * | 1999-07-30 | 2001-04-11 | Univ Glasgow | Peptides conjugated to bile acids/salts |
| US7122533B2 (en) * | 1999-11-29 | 2006-10-17 | The United States Of America As Represented By The Department Of Health And Human Services | Cosalane compounds and methods for their use |
| US6562805B1 (en) * | 1999-11-29 | 2003-05-13 | Purdue Research Foundation | Cosalane compounds and methods for their use |
-
2005
- 2005-04-08 AT AT05732179T patent/ATE442865T1/de not_active IP Right Cessation
- 2005-04-08 AU AU2005231622A patent/AU2005231622B2/en not_active Ceased
- 2005-04-08 EP EP05732179A patent/EP1732612B1/de not_active Expired - Lifetime
- 2005-04-08 CA CA002562266A patent/CA2562266A1/en not_active Abandoned
- 2005-04-08 US US11/547,853 patent/US20080317767A1/en not_active Abandoned
- 2005-04-08 WO PCT/EP2005/003740 patent/WO2005097199A1/en not_active Ceased
- 2005-04-08 EP EP09169971A patent/EP2119455A1/de not_active Withdrawn
- 2005-04-08 DE DE602005016658T patent/DE602005016658D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| AU2005231622A1 (en) | 2005-10-20 |
| CA2562266A1 (en) | 2005-10-20 |
| DE602005016658D1 (de) | 2009-10-29 |
| US20080317767A1 (en) | 2008-12-25 |
| EP2119455A1 (de) | 2009-11-18 |
| WO2005097199A1 (en) | 2005-10-20 |
| EP1732612B1 (de) | 2009-09-16 |
| EP1732612A1 (de) | 2006-12-20 |
| AU2005231622B2 (en) | 2011-05-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |