ATE443160T1 - Für einen spannungsgesteuerten kaliumkanal kodierendes humanes adipositas- suszeptibilitätssgen und dessen verwendung - Google Patents
Für einen spannungsgesteuerten kaliumkanal kodierendes humanes adipositas- suszeptibilitätssgen und dessen verwendungInfo
- Publication number
- ATE443160T1 ATE443160T1 AT05764662T AT05764662T ATE443160T1 AT E443160 T1 ATE443160 T1 AT E443160T1 AT 05764662 T AT05764662 T AT 05764662T AT 05764662 T AT05764662 T AT 05764662T AT E443160 T1 ATE443160 T1 AT E443160T1
- Authority
- AT
- Austria
- Prior art keywords
- obesity
- voltage
- gene encoding
- susceptibility gene
- potassium channel
- Prior art date
Links
- 208000008589 Obesity Diseases 0.000 title abstract 3
- 235000020824 obesity Nutrition 0.000 title abstract 3
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 102000004257 Potassium Channel Human genes 0.000 title 1
- 108020001213 potassium channel Proteins 0.000 title 1
- 208000029078 coronary artery disease Diseases 0.000 abstract 2
- 238000003745 diagnosis Methods 0.000 abstract 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 abstract 2
- 101150060409 kcnab2 gene Proteins 0.000 abstract 2
- 208000030159 metabolic disease Diseases 0.000 abstract 2
- 230000035772 mutation Effects 0.000 abstract 2
- 230000002265 prevention Effects 0.000 abstract 2
- 108700028369 Alleles Proteins 0.000 abstract 1
- 208000016546 Distal 16p11.2 microdeletion syndrome Diseases 0.000 abstract 1
- 208000032928 Dyslipidaemia Diseases 0.000 abstract 1
- 201000001376 Familial Combined Hyperlipidemia Diseases 0.000 abstract 1
- 206010021024 Hypolipidaemia Diseases 0.000 abstract 1
- 102000004877 Insulin Human genes 0.000 abstract 1
- 108090001061 Insulin Proteins 0.000 abstract 1
- 208000017170 Lipid metabolism disease Diseases 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 238000001514 detection method Methods 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 208000029498 hypoalphalipoproteinemia Diseases 0.000 abstract 1
- 229940125396 insulin Drugs 0.000 abstract 1
- 238000012216 screening Methods 0.000 abstract 1
- 208000011580 syndromic disease Diseases 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/172—Haplotypes
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Obesity (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Animal Behavior & Ethology (AREA)
- Hematology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Electrochromic Elements, Electrophoresis, Or Variable Reflection Or Absorption Elements (AREA)
- Electrotherapy Devices (AREA)
- Eye Examination Apparatus (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US57882904P | 2004-06-14 | 2004-06-14 | |
| PCT/IB2005/002356 WO2005123949A2 (en) | 2004-06-14 | 2005-06-14 | Human obesity susceptibility gene encoding a potassium voltage-gated channel and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE443160T1 true ATE443160T1 (de) | 2009-10-15 |
Family
ID=35395853
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05764662T ATE443160T1 (de) | 2004-06-14 | 2005-06-14 | Für einen spannungsgesteuerten kaliumkanal kodierendes humanes adipositas- suszeptibilitätssgen und dessen verwendung |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080193923A1 (de) |
| EP (1) | EP1756316B1 (de) |
| JP (1) | JP2008502341A (de) |
| AT (1) | ATE443160T1 (de) |
| AU (1) | AU2005254806B2 (de) |
| CA (1) | CA2568957A1 (de) |
| DE (1) | DE602005016676D1 (de) |
| DK (1) | DK1756316T3 (de) |
| IL (1) | IL179744A0 (de) |
| WO (1) | WO2005123949A2 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113671179B (zh) * | 2021-09-02 | 2023-10-03 | 中国科学院深圳先进技术研究院 | 一种kcnab2自身抗体的检测用试剂盒及其检测方法和应用 |
| US20240417439A1 (en) * | 2021-10-22 | 2024-12-19 | The Hospital For Sick Children | RECOMBINANT POLYPEPTIDE FOR DISRUPTING INTERACTION OF EAG2 AND KVß2 AND THERAPEUTIC APPLICATIONS THEREOF IN CANCER TREATMENT |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5221900A (en) * | 1991-04-30 | 1993-06-22 | Hewlett-Packard Company | Magnet structure for focusing of magnetic resonance images |
| US5252922A (en) * | 1991-04-30 | 1993-10-12 | Hewlett-Packard Company | Radiofrequency focusing of magnetic resonance images |
| US5185573A (en) * | 1991-04-16 | 1993-02-09 | Hewlett-Packard Company | Method for focusing of magnetic resonance images |
| US6477398B1 (en) * | 1997-11-13 | 2002-11-05 | Randell L. Mills | Resonant magnetic susceptibility imaging (ReMSI) |
| AU2001245489A1 (en) * | 2000-03-07 | 2001-09-17 | Whitehead Institute For Biomedical Research | Human single nucleotide polymorphisms |
| US6682888B1 (en) * | 2000-05-05 | 2004-01-27 | Incyte Corporation | Genes expressed in alzheimer's disease |
| WO2002028999A2 (en) * | 2000-10-03 | 2002-04-11 | Gene Logic, Inc. | Gene expression profiles in granulocytic cells |
| AU2003279980A1 (en) * | 2002-10-16 | 2004-05-04 | Incyte Corporation | Transporters and ion channels |
-
2005
- 2005-06-14 AT AT05764662T patent/ATE443160T1/de not_active IP Right Cessation
- 2005-06-14 JP JP2007516074A patent/JP2008502341A/ja not_active Withdrawn
- 2005-06-14 DK DK05764662.2T patent/DK1756316T3/da active
- 2005-06-14 EP EP05764662A patent/EP1756316B1/de not_active Expired - Lifetime
- 2005-06-14 DE DE602005016676T patent/DE602005016676D1/de not_active Expired - Fee Related
- 2005-06-14 CA CA002568957A patent/CA2568957A1/en not_active Abandoned
- 2005-06-14 AU AU2005254806A patent/AU2005254806B2/en not_active Ceased
- 2005-06-14 US US11/569,193 patent/US20080193923A1/en not_active Abandoned
- 2005-06-14 WO PCT/IB2005/002356 patent/WO2005123949A2/en not_active Ceased
-
2006
- 2006-11-30 IL IL179744A patent/IL179744A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL179744A0 (en) | 2007-05-15 |
| AU2005254806A1 (en) | 2005-12-29 |
| DE602005016676D1 (de) | 2009-10-29 |
| WO2005123949A2 (en) | 2005-12-29 |
| JP2008502341A (ja) | 2008-01-31 |
| CA2568957A1 (en) | 2005-12-29 |
| WO2005123949A3 (en) | 2006-03-16 |
| DK1756316T3 (da) | 2010-01-18 |
| US20080193923A1 (en) | 2008-08-14 |
| AU2005254806B2 (en) | 2009-06-04 |
| EP1756316A2 (de) | 2007-02-28 |
| EP1756316B1 (de) | 2009-09-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 1756316 Country of ref document: EP |
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| REN | Ceased due to non-payment of the annual fee |