ATE444310T1 - Antiidiotypische antikörper die hiv-1 neutralisierende antikörper induzieren - Google Patents

Antiidiotypische antikörper die hiv-1 neutralisierende antikörper induzieren

Info

Publication number
ATE444310T1
ATE444310T1 AT03709690T AT03709690T ATE444310T1 AT E444310 T1 ATE444310 T1 AT E444310T1 AT 03709690 T AT03709690 T AT 03709690T AT 03709690 T AT03709690 T AT 03709690T AT E444310 T1 ATE444310 T1 AT E444310T1
Authority
AT
Austria
Prior art keywords
antibodies
relates
fragments
neutralizing
hiv
Prior art date
Application number
AT03709690T
Other languages
English (en)
Inventor
Renate Kunert
Robert Weik
Gabriela Stiegler
Hermann Katinger
Original Assignee
Polymun Scient Immunbio Forsch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polymun Scient Immunbio Forsch filed Critical Polymun Scient Immunbio Forsch
Application granted granted Critical
Publication of ATE444310T1 publication Critical patent/ATE444310T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4216—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig
    • C07K16/4225—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig against anti-HIV Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT03709690T 2002-01-17 2003-01-17 Antiidiotypische antikörper die hiv-1 neutralisierende antikörper induzieren ATE444310T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP02001250 2002-01-17
PCT/EP2003/000455 WO2003059953A2 (en) 2002-01-17 2003-01-17 Anti-idiotypic antibody inducing hiv-1 neutralizing antibodies

Publications (1)

Publication Number Publication Date
ATE444310T1 true ATE444310T1 (de) 2009-10-15

Family

ID=8185289

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03709690T ATE444310T1 (de) 2002-01-17 2003-01-17 Antiidiotypische antikörper die hiv-1 neutralisierende antikörper induzieren

Country Status (8)

Country Link
US (1) US7625566B2 (de)
EP (1) EP1465928B1 (de)
JP (1) JP4495969B2 (de)
AT (1) ATE444310T1 (de)
AU (1) AU2003214044B8 (de)
CA (1) CA2473163C (de)
DE (1) DE60329461D1 (de)
WO (1) WO2003059953A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1868651A4 (de) 2005-04-12 2010-10-06 Univ Duke Verfahren zur induktion von neutralisierenden antikörpern gegen das hiv-virus
ITTO20070066A1 (it) * 2007-01-30 2008-07-31 Pomona Biotechnologies Llc Anticorpi monoclonali anti-idiotipo mimotopi dell'antigene gp 120 di hiv
JP2010523676A (ja) 2007-04-13 2010-07-15 デューク ユニバーシティ ヒト免疫不全ウイルスに対する中和抗体を誘導する方法
ITTO20080204A1 (it) 2008-03-17 2009-09-18 Pomona Biotechnologies Llc Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a
ITTO20080398A1 (it) * 2008-05-27 2009-11-28 Pomona Biotechnologies Llc Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1
ITTO20080964A1 (it) 2008-12-22 2010-06-23 Natimab Therapeutics S R L Anticorpo monoclonale anti-hcv come medicamento per il trattamento terapeutico e la prevenzione di infezioni da hcv
IT1395961B1 (it) 2009-06-01 2012-11-02 Pomona Biotechnologies Llc Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv)
US20150216973A1 (en) * 2012-08-08 2015-08-06 Network Immunology Inc.. Method for the induction of an immune response
WO2015048635A1 (en) 2013-09-27 2015-04-02 Duke University Mper-liposome conjugates and uses thereof
US20190284259A1 (en) * 2016-07-22 2019-09-19 Georgia State University Research Foundation Monoclonal Antibodies to B Virus And Their Use For Identification Of B Virus Specific Reactive Peptides
WO2021065846A1 (ja) * 2019-09-30 2021-04-08 国立大学法人 熊本大学 抗ＨＩＶ－１ Ｖ３抗体１Ｃ１０（０．５γ）に結合する抗体及びその抗原結合断片並びにその応用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU1025692A (en) * 1991-02-06 1992-08-13 Ciba-Geigy Ag Novel chimeric antiidiotypic monoclonal antibodies
EP0503916A1 (de) * 1991-03-11 1992-09-16 Idec Pharmaceuticals Corporation Verfahren zur Auswahl Antikörperreagenzes; Anti-Idiotype-Antikörper; und Aidsimpfstoffabfassungen
DE69311764T2 (de) * 1992-05-14 1998-02-05 Polymun Scient Immunbio Forsch Peptide, die Antikörper induzieren, die genetisch divergierende HIV-1 Isolationen neutralisieren
AU5361794A (en) * 1992-10-14 1994-05-09 Board Of Trustees Of The Leland Stanford Junior University Enhancement of b cell lymphoma tumor resistance using idiotype/cytokine conjugates
DE69632062T2 (de) 1995-11-02 2004-11-18 Schering Corp. Kontinuierliche, niedrigdosierte zytokine-infusionstherapie
WO1997034636A1 (en) 1996-03-20 1997-09-25 Immunomedics, Inc. Humanization of an anti-carcinoembryonic antigen anti-idiotype antibody and use as a tumor vaccine and for targeting applications
AU729579B2 (en) 1996-10-23 2001-02-01 Trustees Of The University Of Pennsylvania, The Immunotherapy and improved vaccines

Also Published As

Publication number Publication date
WO2003059953A2 (en) 2003-07-24
EP1465928A2 (de) 2004-10-13
CA2473163A1 (en) 2003-07-24
US7625566B2 (en) 2009-12-01
EP1465928B1 (de) 2009-09-30
DE60329461D1 (de) 2009-11-12
JP4495969B2 (ja) 2010-07-07
AU2003214044B2 (en) 2008-06-26
AU2003214044A1 (en) 2003-07-30
CA2473163C (en) 2011-12-06
JP2005517685A (ja) 2005-06-16
WO2003059953B1 (en) 2004-02-26
WO2003059953A3 (en) 2003-12-18
AU2003214044B8 (en) 2008-11-13
US20050080240A1 (en) 2005-04-14

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