ATE445645T1 - Verfahren zur selektion von anti-angiogenese antikörperfragmenten - Google Patents

Verfahren zur selektion von anti-angiogenese antikörperfragmenten

Info

Publication number
ATE445645T1
ATE445645T1 AT01999662T AT01999662T ATE445645T1 AT E445645 T1 ATE445645 T1 AT E445645T1 AT 01999662 T AT01999662 T AT 01999662T AT 01999662 T AT01999662 T AT 01999662T AT E445645 T1 ATE445645 T1 AT E445645T1
Authority
AT
Austria
Prior art keywords
antibody fragments
angiogenesis antibody
selecting anti
angiogenesis
selecting
Prior art date
Application number
AT01999662T
Other languages
English (en)
Inventor
Leonardo Giovannoni
Original Assignee
Philogen Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philogen Spa filed Critical Philogen Spa
Application granted granted Critical
Publication of ATE445645T1 publication Critical patent/ATE445645T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/005—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies constructed by phage libraries
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
AT01999662T 2000-12-06 2001-12-06 Verfahren zur selektion von anti-angiogenese antikörperfragmenten ATE445645T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT2000FI000247A IT1317108B1 (it) 2000-12-06 2000-12-06 Processo per la selezione di frammenti anticorporali anti-angiogenesi,frammenti anticorpali anti-angiogenesi cosi' ottenuti e loro uso.
PCT/EP2001/014330 WO2002046455A2 (en) 2000-12-06 2001-12-06 Process for selecting anti-angiogenesis antibody fragments, anti-angiogenesis antibody fragments thus obtained and their use

Publications (1)

Publication Number Publication Date
ATE445645T1 true ATE445645T1 (de) 2009-10-15

Family

ID=11442008

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01999662T ATE445645T1 (de) 2000-12-06 2001-12-06 Verfahren zur selektion von anti-angiogenese antikörperfragmenten

Country Status (10)

Country Link
US (1) US7723269B2 (de)
EP (1) EP1339750B1 (de)
JP (1) JP2004527226A (de)
AT (1) ATE445645T1 (de)
AU (1) AU2002221938A1 (de)
CA (1) CA2430713A1 (de)
DE (1) DE60140205D1 (de)
DK (1) DK1339750T3 (de)
IT (1) IT1317108B1 (de)
WO (1) WO2002046455A2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0307300A (pt) * 2002-02-01 2005-09-06 Cargill Inc Integração de pelo menos dois processos para reutilizar ácido
EP1539235A2 (de) 2002-07-01 2005-06-15 Human Genome Sciences, Inc. Spezifisch an reg iv bindende antikörper
JP2008514900A (ja) 2004-07-30 2008-05-08 アデザ・バイオメデイカル・コーポレイシヨン 疾病および他の状態のマーカーとしての癌胎児性フィブロネクチンならびに癌胎児性フィブロネクチンの検出のための方法
US7785591B2 (en) 2004-10-14 2010-08-31 Morphosys Ag Identification and characterization of function-blocking anti-ED-B-fibronectin antibodies
WO2008120101A2 (en) 2007-04-02 2008-10-09 Philogen S.P.A. The ed-a antigen of fibrinogen is associated with the neovasculature of tumour metastases
EP2167541B1 (de) 2007-07-25 2012-12-19 Philogen S.p.A. Das fibronektin ed-a-antigen ist mit der neovaskulatur von tumormetastasen assoziiert
DK3281952T3 (da) 2007-10-30 2020-08-03 Philogen Spa Antigen, der er forbundet med reumatoid artritis
CA2748401C (en) 2009-01-07 2017-09-12 Philogen S.P.A. Antigens associated with endometriosis
ES2743423T3 (es) 2012-10-03 2020-02-19 Philogen Spa Conjugado de anticuerpos para su uso en el tratamiento de una enfermedad inflamatoria intestinal
JP6925431B2 (ja) 2016-11-09 2021-08-25 フィロジェン エッセ．ピー．アー． Ｉｌ２及びｔｎｆ突然変異体のイムノコンジュゲート
CN110997718B (zh) 2017-06-07 2023-11-10 菲洛根股份公司 血管内皮生长因子/抗纤连蛋白抗体融合蛋白
EP3502139A1 (de) 2017-12-19 2019-06-26 Philogen S.p.A. Antikörper gegen tumorantigene
US20190351031A1 (en) 2018-05-16 2019-11-21 Halozyme, Inc. Methods of selecting subjects for combination cancer therapy with a polymer-conjugated soluble ph20
US11505782B2 (en) 2018-06-04 2022-11-22 Calidi Biotherapeutics, Inc. Cell-based vehicles for potentiation of viral therapy
EA202000353A1 (ru) 2018-06-04 2022-01-14 Калиди Биотерапьютикс, Инк. Основанные на клетках носители для потенциализации вирусной терапии
CA3106056A1 (en) 2018-07-26 2020-01-30 Ospedale Pediatrico Bambino Gesu (Opbg) Therapeutic preparations of gamma-delta t cells and natural killer cells and methods for manufacture and use
CA3116192C (en) 2018-11-06 2025-09-23 Calidi Biotherapeutics (Nevada), Inc. IMPROVED SYSTEMS FOR CELL-MEDIATED ONCOLYTIC VIRAL THERAPY
WO2021226520A1 (en) 2020-05-08 2021-11-11 Kiromic BioPharma, Inc. Peptide compositions for the treatment of pathogenic infections
EP4175650A1 (de) 2020-07-06 2023-05-10 Kiromic BioPharma, Inc. Mesothelinisoformbindende moleküle und chimäre pd1-rezeptormoleküle, zellen damit und verwendungen davon
WO2022108627A1 (en) 2020-11-18 2022-05-27 Kiromic Biopharma, Inc.Kiromic Biopharma, Inc. Gamma-delta t cell manufacturing processes and chimeric pd1 receptor molecules
WO2025184411A1 (en) 2024-02-27 2025-09-04 Calidi Biotherapeutics (Nevada), Inc. Serum-resistant eev viruses and uses thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8921880D0 (en) * 1989-09-28 1989-11-15 Medical Res Council Improvements in or relating to hybridomas
US5565332A (en) * 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
GB9610967D0 (en) * 1996-05-24 1996-07-31 Cambridge Antibody Tech Specific binding members,materials and methods
US6190660B1 (en) * 1996-05-31 2001-02-20 Health Research, Inc. Anti-endoglin monoclonal antibodies and their use in antiangiogenic therapy
IT1307864B1 (it) * 1999-04-20 2001-11-19 Istituto Naz Per La Ricerca Su Metodo diagnostico per il riconoscimento di neoplasie umane attraversola determinazione dell'isoforma ctn-c della tn-c, frammenti di

Also Published As

Publication number Publication date
EP1339750A2 (de) 2003-09-03
WO2002046455A3 (en) 2002-11-14
JP2004527226A (ja) 2004-09-09
AU2002221938A1 (en) 2002-06-18
CA2430713A1 (en) 2002-06-13
DK1339750T3 (da) 2010-02-15
EP1339750B1 (de) 2009-10-14
WO2002046455A2 (en) 2002-06-13
ITFI20000247A1 (it) 2002-06-06
DE60140205D1 (de) 2009-11-26
US7723269B2 (en) 2010-05-25
IT1317108B1 (it) 2003-05-26
US20040091973A1 (en) 2004-05-13

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