ATE447038T1 - Schweineadenovirus vektor - Google Patents
Schweineadenovirus vektorInfo
- Publication number
- ATE447038T1 ATE447038T1 AT99917515T AT99917515T ATE447038T1 AT E447038 T1 ATE447038 T1 AT E447038T1 AT 99917515 T AT99917515 T AT 99917515T AT 99917515 T AT99917515 T AT 99917515T AT E447038 T1 ATE447038 T1 AT E447038T1
- Authority
- AT
- Austria
- Prior art keywords
- pav
- genome
- expression
- genomes
- recombinant
- Prior art date
Links
- 239000013598 vector Substances 0.000 title abstract 3
- 241000282898 Sus scrofa Species 0.000 title abstract 2
- 241000701161 unidentified adenovirus Species 0.000 title 1
- 241001492389 Porcine adenovirus 3 Species 0.000 abstract 6
- 108020004414 DNA Proteins 0.000 abstract 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 239000012472 biological sample Substances 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 238000010276 construction Methods 0.000 abstract 1
- 238000001415 gene therapy Methods 0.000 abstract 1
- 230000006801 homologous recombination Effects 0.000 abstract 1
- 238000002744 homologous recombination Methods 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000002458 infectious effect Effects 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 229940031626 subunit vaccine Drugs 0.000 abstract 1
- 238000001890 transfection Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10322—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10361—Methods of inactivation or attenuation
- C12N2710/10362—Methods of inactivation or attenuation by genetic engineering
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Virology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Gastroenterology & Hepatology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8188298P | 1998-04-15 | 1998-04-15 | |
| PCT/US1999/008220 WO1999053047A2 (en) | 1998-04-15 | 1999-04-15 | Porcine adenovirus type 3 genome |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE447038T1 true ATE447038T1 (de) | 2009-11-15 |
Family
ID=22167011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99917515T ATE447038T1 (de) | 1998-04-15 | 1999-04-15 | Schweineadenovirus vektor |
Country Status (9)
| Country | Link |
|---|---|
| US (3) | US6492343B1 (de) |
| EP (2) | EP1071758B1 (de) |
| JP (1) | JP2002515222A (de) |
| AT (1) | ATE447038T1 (de) |
| AU (1) | AU766670B2 (de) |
| CA (3) | CA2800231A1 (de) |
| DE (1) | DE69941596D1 (de) |
| DK (1) | DK1071758T3 (de) |
| WO (1) | WO1999053047A2 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AUPO856097A0 (en) * | 1997-08-14 | 1997-09-04 | Commonwealth Scientific And Industrial Research Organisation | Vector |
| US6492343B1 (en) | 1998-04-15 | 2002-12-10 | University Of Saskatchewan | Porcine adenovirus type 3 genome |
| US6328958B1 (en) * | 1998-08-28 | 2001-12-11 | Duke University | Deleted adenovirus vectors and methods of making and administering the same |
| FR2789695B1 (fr) * | 1999-02-11 | 2003-03-07 | Merial Sas | Vecteurs et vaccins viraux a base d'adenovirus porcins recombines et replicatifs |
| EP1311698A2 (de) * | 2000-05-03 | 2003-05-21 | University Of Guelph | Schweine-adenovirus 5 vektor und impfstoff |
| MY146518A (en) * | 2001-03-27 | 2012-08-15 | Univ Saskatchewan | Methods to culture circovirus. |
| US7569217B2 (en) * | 2001-09-24 | 2009-08-04 | University Of Saskatchewan | Porcine adenovirus E1 and E4 regions |
| US7906311B2 (en) | 2002-03-20 | 2011-03-15 | Merial Limited | Cotton rat lung cells for virus culture |
| AU2003255967A1 (en) * | 2002-07-19 | 2004-02-09 | University Of Saskatchewan | Pav regions for encapsidation and e1 transcriptioonal control |
| AU2003287831A1 (en) * | 2002-12-20 | 2004-07-14 | Qbiogene Inc. | Method and kit for detecting replication competent adenoviruses |
| WO2004108755A2 (en) * | 2003-06-10 | 2004-12-16 | University Of Saskatchewan | Chimeric adenovirus capsid proteins |
| BRPI0714932A2 (pt) * | 2006-07-28 | 2013-05-21 | Commw Scient Ind Res Org | mÉtodos e composiÇÕes para aumento do tropismo tecidual de vetores adenovirais recombinantes |
| US20110135688A1 (en) * | 2009-12-04 | 2011-06-09 | Michael Sheppard | Methods and Compositions for Increasing Titer of Recombinant Porcine Adenovirus-3 Vectors |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA1319101C (en) | 1986-09-03 | 1993-06-15 | Marta Iris Sabara | Rotavirus nucleocapsid protein with or without binding peptides as immunologic carriers for macromolecules |
| US5670488A (en) * | 1992-12-03 | 1997-09-23 | Genzyme Corporation | Adenovirus vector for gene therapy |
| US6080569A (en) * | 1993-06-24 | 2000-06-27 | Merck & Co., Inc. | Adenovirus vectors generated from helper viruses and helper-dependent vectors |
| WO1998010087A1 (en) * | 1996-09-06 | 1998-03-12 | Trustees Of The University Of Pennsylvania | Chimpanzee adenovirus vectors |
| AUPO856097A0 (en) | 1997-08-14 | 1997-09-04 | Commonwealth Scientific And Industrial Research Organisation | Vector |
| US6492343B1 (en) | 1998-04-15 | 2002-12-10 | University Of Saskatchewan | Porcine adenovirus type 3 genome |
| AU3375500A (en) | 1999-02-24 | 2000-09-14 | Purdue Research Foundation | Adenoviral vectors, proteins and methods for their use |
| WO2002012524A2 (en) | 2000-08-03 | 2002-02-14 | Onyx Pharmaceuticals, Inc. | Adenovirus e1b-55k single amino acid mutants and methods of use |
| IL152420A0 (en) | 2001-02-23 | 2003-05-29 | Novartis Ag | Novel oncolytic adenoviral vectors |
| US20030143200A1 (en) | 2001-09-24 | 2003-07-31 | Tikoo Suresh K. | Porcine adenovirus E1 region |
| US7569217B2 (en) | 2001-09-24 | 2009-08-04 | University Of Saskatchewan | Porcine adenovirus E1 and E4 regions |
-
1999
- 1999-04-14 US US09/292,034 patent/US6492343B1/en not_active Ceased
- 1999-04-15 EP EP99917515A patent/EP1071758B1/de not_active Expired - Lifetime
- 1999-04-15 EP EP09011668A patent/EP2145961A3/de not_active Withdrawn
- 1999-04-15 CA CA2800231A patent/CA2800231A1/en not_active Abandoned
- 1999-04-15 AT AT99917515T patent/ATE447038T1/de not_active IP Right Cessation
- 1999-04-15 CA CA2325574A patent/CA2325574C/en not_active Expired - Lifetime
- 1999-04-15 WO PCT/US1999/008220 patent/WO1999053047A2/en not_active Ceased
- 1999-04-15 DK DK99917515T patent/DK1071758T3/da active
- 1999-04-15 JP JP2000543595A patent/JP2002515222A/ja not_active Withdrawn
- 1999-04-15 DE DE69941596T patent/DE69941596D1/de not_active Expired - Lifetime
- 1999-04-15 AU AU35617/99A patent/AU766670B2/en not_active Expired
- 1999-04-15 CA CA2718812A patent/CA2718812C/en not_active Expired - Lifetime
-
2002
- 2002-09-16 US US10/245,603 patent/US7335353B2/en not_active Expired - Fee Related
-
2006
- 2006-09-08 US US11/518,612 patent/USRE40930E1/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002515222A (ja) | 2002-05-28 |
| WO1999053047A3 (en) | 2000-01-13 |
| CA2325574A1 (en) | 1999-10-21 |
| USRE40930E1 (en) | 2009-10-06 |
| AU3561799A (en) | 1999-11-01 |
| WO1999053047A2 (en) | 1999-10-21 |
| CA2800231A1 (en) | 1999-10-21 |
| DE69941596D1 (de) | 2009-12-10 |
| CA2718812C (en) | 2014-07-29 |
| AU766670B2 (en) | 2003-10-23 |
| EP2145961A3 (de) | 2010-04-14 |
| DK1071758T3 (da) | 2009-12-21 |
| US20030130187A1 (en) | 2003-07-10 |
| CA2718812A1 (en) | 1999-10-21 |
| US7335353B2 (en) | 2008-02-26 |
| EP2145961A2 (de) | 2010-01-20 |
| EP1071758A1 (de) | 2001-01-31 |
| EP1071758B1 (de) | 2009-10-28 |
| CA2325574C (en) | 2013-01-29 |
| US6492343B1 (en) | 2002-12-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |