ATE449088T1 - Thiazolinsäure-derivate - Google Patents
Thiazolinsäure-derivateInfo
- Publication number
- ATE449088T1 ATE449088T1 AT03021526T AT03021526T ATE449088T1 AT E449088 T1 ATE449088 T1 AT E449088T1 AT 03021526 T AT03021526 T AT 03021526T AT 03021526 T AT03021526 T AT 03021526T AT E449088 T1 ATE449088 T1 AT E449088T1
- Authority
- AT
- Austria
- Prior art keywords
- acid derivatives
- thiazolic
- thiazolic acid
- derivatives
- thiazoline
- Prior art date
Links
- 239000002253 acid Substances 0.000 title 1
- 239000002738 chelating agent Substances 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/10—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/04—Chelating agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/624,289 US5840739A (en) | 1992-11-16 | 1996-03-29 | Thiazoline acid derivatives |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449088T1 true ATE449088T1 (de) | 2009-12-15 |
Family
ID=24501405
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03021526T ATE449088T1 (de) | 1996-03-29 | 1997-03-31 | Thiazolinsäure-derivate |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5840739A (de) |
| EP (3) | EP2096112A3 (de) |
| JP (2) | JP3800559B2 (de) |
| KR (1) | KR20000005100A (de) |
| AT (1) | ATE449088T1 (de) |
| AU (1) | AU715889B2 (de) |
| BR (1) | BR9708460A (de) |
| CA (1) | CA2250243C (de) |
| DE (1) | DE69739670D1 (de) |
| NO (1) | NO315608B1 (de) |
| NZ (2) | NZ332049A (de) |
| PL (1) | PL329172A1 (de) |
| WO (1) | WO1997036885A1 (de) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7045531B1 (en) | 1997-03-11 | 2006-05-16 | The General Hospital Corporation | Composition comprising a metal chelator and a method of treating amyloidosis by administering the metal chelator |
| NZ506528A (en) * | 1998-02-04 | 2002-11-26 | Univ Florida | Subcutaneous HBED administration to treat iron overload disorders |
| US6638711B1 (en) | 1999-04-29 | 2003-10-28 | The General Hospital Corporation | Methods for identifying an agent that inhibits oxygen-dependent hydrogen peroxide formation activity but does not inhibit superoxide-dependent hydrogen peroxide formation |
| US6323218B1 (en) | 1998-03-11 | 2001-11-27 | The General Hospital Corporation | Agents for use in the treatment of Alzheimer's disease |
| US6083966A (en) * | 1998-08-31 | 2000-07-04 | University Of Florida | Thiazoline acid derivatives |
| US6159983A (en) * | 1998-09-18 | 2000-12-12 | University Of Florida | Method and composition for treatment of inflammatory bowel disease |
| EP1488791A3 (de) * | 1998-09-21 | 2005-04-06 | University Of Florida Research Foundation, Inc. | Mittel gegen malaria |
| NZ509172A (en) * | 1998-09-21 | 2004-02-27 | Univ Florida | Antimalarial agents |
| AU2293101A (en) | 1999-12-21 | 2001-07-03 | Geltex Pharmaceuticals, Inc. | Method for making hbed |
| US6689788B1 (en) * | 2000-08-25 | 2004-02-10 | University Of Florida | Method and composition for treatment of inflammatory bowel disease |
| AU2003239472A1 (en) | 2002-05-15 | 2003-12-02 | Genzyme Corporation | Synthesis of benzonitriles and benzimidates |
| US20040132789A1 (en) * | 2002-08-22 | 2004-07-08 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
| US20040044220A1 (en) * | 2002-08-22 | 2004-03-04 | University Of Florida | Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin |
| AU2003267245C1 (en) | 2002-09-20 | 2008-05-29 | Promega Corporation | Luminescence-based methods and probes for measuring cytochrome P450 activity |
| AU2003270473A1 (en) * | 2003-09-09 | 2005-04-27 | University Of Florida | Desferrithiocin derivatives and their use as iron chelators |
| ES2732625T3 (es) | 2005-04-04 | 2019-11-25 | Univ Florida | Análogos de poliéter de desferritiocina |
| EP2272973B1 (de) * | 2005-05-31 | 2015-05-27 | Promega Corporation | Luminogene und fluorogene Verbindungen und Verfahren für den Nachweis von Molekülen oder Leiden |
| CN104003955A (zh) * | 2007-03-15 | 2014-08-27 | 佛罗里达大学研究基金公司 | 去铁硫辛聚醚类似物 |
| US8288559B2 (en) | 2008-08-18 | 2012-10-16 | Promega Corporation | Luminogenic compounds and methods to detect cytochrome P450 3A enzymes |
| BR112012001761A2 (pt) * | 2009-07-27 | 2017-05-09 | Ferrokin Bioscience Inc | composto de formula i, composto farmacêutica e método de tratamento de uma condição mediada por metal em um indivduo |
| BR112014014544A2 (pt) | 2011-12-16 | 2017-06-13 | Univ Florida | usos de análogos de 4'-desferritiocina |
| US10010535B2 (en) | 2013-11-22 | 2018-07-03 | University Of Florida Research Foundation, Incorporated | Desferrithiocin analogs and uses thereof |
| WO2015116867A1 (en) | 2014-01-29 | 2015-08-06 | Promega Corporation | Quinone-masked probes as labeling reagents for cell uptake measurements |
| WO2016176343A1 (en) | 2015-04-27 | 2016-11-03 | University Of Florida Research Foundation, Incorporated | Metabolically programmed metal chelators and uses thereof |
| KR20210015892A (ko) | 2018-05-29 | 2021-02-10 | 세르시 테라퓨틱스 인코포레이티드 | 통증 치료를 위한 화합물, 이를 포함하는 조성물 및 이를 사용하는 방법 |
| CA3136102A1 (en) | 2019-05-10 | 2020-11-19 | Cersci Therapeutics, Inc. | Manufacturing methods and polymorphs of a thiazoline anti-hyperalgesic agent |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1137529A (en) * | 1967-05-04 | 1968-12-27 | Wyeth John & Brother Ltd | Thiazole compositions |
| CY800A (en) * | 1968-04-09 | 1976-12-01 | Wyeth John & Brother Ltd | Novel thiazoline derivatives, the preparation thereof and compositions containing the same |
| DE3002989A1 (de) * | 1980-01-29 | 1981-07-30 | Hoechst Ag, 6000 Frankfurt | Hydroxyphenyl-thiazol, -thiazolin und -thiazolidin-carbonsaeuren, verfahren zu ihrer herstellung und ihre verwendung zur beeinflussung des kollagenstoffwechsels |
| EP0045281B1 (de) * | 1980-07-28 | 1985-05-08 | Ciba-Geigy Ag | Thiazolinderivate und Verfahren zu ihrer Herstellung |
| US5393777A (en) * | 1990-11-15 | 1995-02-28 | State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon Health Sciences University | Deferration using anguibactin siderophore |
| AU5602594A (en) * | 1992-11-16 | 1994-06-08 | University Of Florida Research Foundation, Inc. | 2-(pyrid-2'-yl)-2-thiazoline-4(s)-carboxylic acid derivatives |
-
1996
- 1996-03-29 US US08/624,289 patent/US5840739A/en not_active Expired - Fee Related
-
1997
- 1997-03-31 NZ NZ332049A patent/NZ332049A/en unknown
- 1997-03-31 AT AT03021526T patent/ATE449088T1/de not_active IP Right Cessation
- 1997-03-31 CA CA002250243A patent/CA2250243C/en not_active Expired - Fee Related
- 1997-03-31 KR KR1019980707738A patent/KR20000005100A/ko not_active Ceased
- 1997-03-31 EP EP09160649A patent/EP2096112A3/de not_active Withdrawn
- 1997-03-31 PL PL97329172A patent/PL329172A1/xx unknown
- 1997-03-31 NZ NZ509967A patent/NZ509967A/en unknown
- 1997-03-31 AU AU25410/97A patent/AU715889B2/en not_active Ceased
- 1997-03-31 BR BR9708460-3A patent/BR9708460A/pt not_active Application Discontinuation
- 1997-03-31 WO PCT/US1997/004666 patent/WO1997036885A1/en not_active Ceased
- 1997-03-31 JP JP53533897A patent/JP3800559B2/ja not_active Expired - Fee Related
- 1997-03-31 DE DE69739670T patent/DE69739670D1/de not_active Expired - Fee Related
- 1997-03-31 EP EP97916924A patent/EP0900209A4/de not_active Withdrawn
- 1997-03-31 EP EP03021526A patent/EP1380577B1/de not_active Expired - Lifetime
-
1998
- 1998-09-28 NO NO19984508A patent/NO315608B1/no not_active IP Right Cessation
-
2006
- 2006-03-13 JP JP2006067600A patent/JP2006152004A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| KR20000005100A (ko) | 2000-01-25 |
| US5840739A (en) | 1998-11-24 |
| EP0900209A4 (de) | 2001-09-19 |
| NZ332049A (en) | 2001-04-27 |
| AU2541097A (en) | 1997-10-22 |
| JP3800559B2 (ja) | 2006-07-26 |
| PL329172A1 (en) | 1999-03-15 |
| NO984508L (no) | 1998-11-23 |
| JP2000505086A (ja) | 2000-04-25 |
| WO1997036885A1 (en) | 1997-10-09 |
| NO984508D0 (no) | 1998-09-28 |
| CA2250243C (en) | 2002-10-08 |
| BR9708460A (pt) | 2000-01-04 |
| CA2250243A1 (en) | 1997-10-09 |
| EP0900209A1 (de) | 1999-03-10 |
| EP2096112A3 (de) | 2009-09-09 |
| EP1380577B1 (de) | 2009-11-18 |
| AU715889B2 (en) | 2000-02-10 |
| JP2006152004A (ja) | 2006-06-15 |
| EP1380577A1 (de) | 2004-01-14 |
| NO315608B1 (no) | 2003-09-29 |
| DE69739670D1 (de) | 2009-12-31 |
| NZ509967A (en) | 2005-06-24 |
| EP2096112A2 (de) | 2009-09-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69739670D1 (de) | Thiazolinsäure-Derivate | |
| NO940789D0 (no) | Quinolinkarboksylsyrederivater, deres fremstilling og anvendelse | |
| DK0788360T3 (da) | Boronsyreester- og syreforbindelser, deres syntese og anvendelser | |
| DE3867572D1 (de) | Benzothiazol-derivat und es als aktiven bestandteil enthaltendes antirheumatisches mittel. | |
| ATE263147T1 (de) | Derivate von aryloxyarylsulfonylamino hydroxyaminsäuren | |
| DE69316717D1 (de) | Inhibitoren mit zweifacher Wirkung | |
| NO302474B1 (no) | Sakarinderivater, farmasöytisk sammensetning og anvendelse derav | |
| ES2182234T3 (es) | Inhibidores de metaloproteasa. | |
| FI963158A0 (fi) | Raskas korkealämpötilainen puristinlaite | |
| ES2179587T3 (es) | Utilizacion de betainas como agentes antitranspirantes. | |
| DE69329996D1 (de) | Inhibitoren retroviraler proteasen | |
| DK0952148T3 (da) | Cyclobutylaryloxyarylsulfonylaminohydroxamsyrederivater | |
| ES2083396T3 (es) | Acidos fenilalcan(en)oicos. | |
| FI860073A0 (fi) | 6,7-disubstituerade 1-cyklopropyl-1,4-dihydro-4-oxo-1,8-naftyridin-3-karboxylsyror. | |
| ATE224350T1 (de) | Inhibition der matrix metalloproteasen durch 2- (omega-aroylalkyl)-4-biaryl-4-oxobutansäuren | |
| FI925544A7 (fi) | Bentsoehappojohdannaisia leukotrieeniin liittyvien sairauksien hoitami seen | |
| DK0617959T3 (da) | Lægemiddel til behandling af hudsygdomme | |
| DK0490634T3 (da) | Quinoliniumsaltmellemprodukter | |
| DE59608306D1 (de) | Schaltung zur Stromversorgung mehrerer Leistungsverstärker | |
| DE69401967D1 (de) | Abspaltbare Hydroxycarbonsäuren | |
| PT1098871E (pt) | Derivados de ester fenilico de alfa-aminoacidos | |
| FI971625L (fi) | Teräksen lämpökäsittely | |
| DK0412941T3 (da) | Phospholipider til behandling af dissemineret sklerose | |
| DE69524574D1 (de) | Enzymatische spaltung von substituierter 2-methylpropionsäure | |
| KR950007488U (ko) | 전력 증폭 구동용 전원 선택회로 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |