ATE449187T1 - Molekulare eigenschaften von nichtkleinzelligem lungenkrebs - Google Patents
Molekulare eigenschaften von nichtkleinzelligem lungenkrebsInfo
- Publication number
- ATE449187T1 ATE449187T1 AT02794901T AT02794901T ATE449187T1 AT E449187 T1 ATE449187 T1 AT E449187T1 AT 02794901 T AT02794901 T AT 02794901T AT 02794901 T AT02794901 T AT 02794901T AT E449187 T1 ATE449187 T1 AT E449187T1
- Authority
- AT
- Austria
- Prior art keywords
- sage
- small cell
- gene expression
- lung cancer
- normal
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/112—Disease subtyping, staging or classification
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Pathology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- General Engineering & Computer Science (AREA)
- Hospice & Palliative Care (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US31240001P | 2001-08-16 | 2001-08-16 | |
| PCT/US2002/026027 WO2003015613A2 (en) | 2001-08-16 | 2002-08-16 | Molecular characteristics of non-small cell lung cancer |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449187T1 true ATE449187T1 (de) | 2009-12-15 |
Family
ID=23211260
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT02794901T ATE449187T1 (de) | 2001-08-16 | 2002-08-16 | Molekulare eigenschaften von nichtkleinzelligem lungenkrebs |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US7332590B2 (de) |
| EP (1) | EP1453977B1 (de) |
| JP (1) | JP2005503145A (de) |
| AT (1) | ATE449187T1 (de) |
| AU (1) | AU2002355963A1 (de) |
| CA (1) | CA2456334A1 (de) |
| DE (1) | DE60234467D1 (de) |
| WO (1) | WO2003015613A2 (de) |
Families Citing this family (67)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005503145A (ja) * | 2001-08-16 | 2005-02-03 | ザ ユナイテッド ステイツ オブ アメリカ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 非小細胞肺癌の分子特性 |
| ATE331044T1 (de) * | 2003-03-04 | 2006-07-15 | Pamgene Bv | Verfahren zur integrierten integritätsbewertung und analyse von nukleinsäuren |
| GB0307428D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Compartmentalised combinatorial chemistry |
| GB0307403D0 (en) | 2003-03-31 | 2003-05-07 | Medical Res Council | Selection by compartmentalised screening |
| US20060078893A1 (en) | 2004-10-12 | 2006-04-13 | Medical Research Council | Compartmentalised combinatorial chemistry by microfluidic control |
| JP4724657B2 (ja) * | 2003-05-30 | 2011-07-13 | アストラゼネカ ユーケー リミテッド | プロセス |
| EP3305919A1 (de) * | 2003-06-10 | 2018-04-11 | The Trustees of Boston University | Nachweismethoden für lungenerkrankungen |
| US20060003391A1 (en) * | 2003-08-11 | 2006-01-05 | Ring Brian Z | Reagents and methods for use in cancer diagnosis, classification and therapy |
| CA2540894A1 (en) * | 2003-10-03 | 2005-04-14 | Bayer Pharmaceuticals Corporation | Gene expression profiles and methods of use |
| ATE496142T1 (de) | 2004-03-23 | 2011-02-15 | Oncotherapy Science Inc | Verfahren zur diagnose von nicht-kleinzelligem lungenkrebs |
| US20050221339A1 (en) | 2004-03-31 | 2005-10-06 | Medical Research Council Harvard University | Compartmentalised screening by microfluidic control |
| US7968287B2 (en) | 2004-10-08 | 2011-06-28 | Medical Research Council Harvard University | In vitro evolution in microfluidic systems |
| WO2006056080A1 (en) * | 2004-11-29 | 2006-06-01 | Diagnocure Inc. | Gpx2 a specific and sensitive target for lung cancer diagnosis, prognosis and/or theranosis |
| US20100035244A1 (en) | 2005-04-14 | 2010-02-11 | The Trustees Of Boston University | Diagnostic for lung disorders using class prediction |
| US7504225B2 (en) | 2005-05-12 | 2009-03-17 | Applied Genomics, Inc. | Reagents and methods for use in cancer diagnosis, classification and therapy |
| KR100710462B1 (ko) | 2005-08-24 | 2007-04-24 | 광주과학기술원 | 폐암 진단용 퍼옥시레독신-i자가항체 마커 및 이를 이용한진단키트 |
| JP2009536313A (ja) | 2006-01-11 | 2009-10-08 | レインダンス テクノロジーズ, インコーポレイテッド | ナノリアクターの形成および制御において使用するマイクロ流体デバイスおよび方法 |
| WO2007103541A2 (en) | 2006-03-09 | 2007-09-13 | The Trustees Of Boston University | Diagnostic and prognostic methods for lung disorders using gene expression profiles from nose epithelial cells |
| US9562837B2 (en) | 2006-05-11 | 2017-02-07 | Raindance Technologies, Inc. | Systems for handling microfludic droplets |
| ATE540750T1 (de) | 2006-05-11 | 2012-01-15 | Raindance Technologies Inc | Mikrofluidische vorrichtung und verfahren |
| EP3536396B1 (de) | 2006-08-07 | 2022-03-30 | The President and Fellows of Harvard College | Fluorkohlenstoffemulsionsstabilisierende tenside |
| EA010352B1 (ru) * | 2006-10-09 | 2008-08-29 | Институт Молекулярной Генетики Российской Академии Наук (Имг Ран) | Способ дифференциального анализа протеомов |
| US8772046B2 (en) | 2007-02-06 | 2014-07-08 | Brandeis University | Manipulation of fluids and reactions in microfluidic systems |
| US8592221B2 (en) | 2007-04-19 | 2013-11-26 | Brandeis University | Manipulation of fluids, fluid components and reactions in microfluidic systems |
| JP2010538680A (ja) | 2007-09-19 | 2010-12-16 | ザ トラスティーズ オブ ボストン ユニバーシティー | 肺疾患に対する薬剤開発のための新規経路の同定 |
| JP5583117B2 (ja) * | 2008-05-14 | 2014-09-03 | ユニバーシティー ヘルス ネットワーク | 非小細胞肺癌およびアジュバント化学療法に関する予後診断的および予測的な遺伝子シグネチャー |
| EP2145964A1 (de) * | 2008-07-17 | 2010-01-20 | Universität Zu Köln | Verfahren zur Früherkennung und Prognose von Lungenkrebs |
| EP2315629B1 (de) | 2008-07-18 | 2021-12-15 | Bio-Rad Laboratories, Inc. | Tröpfchenbibliotheken |
| US12038438B2 (en) | 2008-07-18 | 2024-07-16 | Bio-Rad Laboratories, Inc. | Enzyme quantification |
| US10236078B2 (en) | 2008-11-17 | 2019-03-19 | Veracyte, Inc. | Methods for processing or analyzing a sample of thyroid tissue |
| US9495515B1 (en) | 2009-12-09 | 2016-11-15 | Veracyte, Inc. | Algorithms for disease diagnostics |
| CN102341709A (zh) * | 2009-03-04 | 2012-02-01 | 霍夫曼-拉罗奇有限公司 | 作为肺鳞状细胞癌标志物的丝氨酸蛋白酶抑制蛋白b13 |
| EP3415235B1 (de) | 2009-03-23 | 2025-11-12 | Bio-Rad Laboratories, Inc. | Manipulation von mikrofluidiktröpfchen |
| US8669057B2 (en) | 2009-05-07 | 2014-03-11 | Veracyte, Inc. | Methods and compositions for diagnosis of thyroid conditions |
| WO2011042564A1 (en) | 2009-10-09 | 2011-04-14 | Universite De Strasbourg | Labelled silica-based nanomaterial with enhanced properties and uses thereof |
| EP2493916B1 (de) * | 2009-10-26 | 2016-06-08 | Externautics S.p.A. | Marker für lungentumore und deren verwendung |
| CA2780633C (en) | 2009-11-13 | 2019-06-11 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Diazeniumdiolated compounds, pharmaceutical compositions, and method of treating cancer |
| EP2517025B1 (de) | 2009-12-23 | 2019-11-27 | Bio-Rad Laboratories, Inc. | Verfahren zur reduzierung des austauschs von molekülen zwischen tröpfchen |
| US9366632B2 (en) | 2010-02-12 | 2016-06-14 | Raindance Technologies, Inc. | Digital analyte analysis |
| US10351905B2 (en) | 2010-02-12 | 2019-07-16 | Bio-Rad Laboratories, Inc. | Digital analyte analysis |
| CA2789425C (en) | 2010-02-12 | 2020-04-28 | Raindance Technologies, Inc. | Digital analyte analysis with polymerase error correction |
| US9399797B2 (en) | 2010-02-12 | 2016-07-26 | Raindance Technologies, Inc. | Digital analyte analysis |
| WO2012045012A2 (en) | 2010-09-30 | 2012-04-05 | Raindance Technologies, Inc. | Sandwich assays in droplets |
| EP3859011A1 (de) | 2011-02-11 | 2021-08-04 | Bio-Rad Laboratories, Inc. | Verfahren zur bildung gemischter tröpfchen |
| EP3736281A1 (de) | 2011-02-18 | 2020-11-11 | Bio-Rad Laboratories, Inc. | Zusammensetzungen und verfahren für molekulare etikettierung |
| US8841071B2 (en) | 2011-06-02 | 2014-09-23 | Raindance Technologies, Inc. | Sample multiplexing |
| EP3709018A1 (de) | 2011-06-02 | 2020-09-16 | Bio-Rad Laboratories, Inc. | Mikrofluidische vorrichtung zum nachweis von komponenten einer chemischen reaktion |
| US8658430B2 (en) | 2011-07-20 | 2014-02-25 | Raindance Technologies, Inc. | Manipulating droplet size |
| EP3495817B1 (de) | 2012-02-10 | 2024-10-16 | Bio-Rad Laboratories, Inc. | Molekulardiagnostischer screeningtest |
| EP3524693A1 (de) | 2012-04-30 | 2019-08-14 | Raindance Technologies, Inc. | Digitale analytanalyse |
| EP3626308A1 (de) | 2013-03-14 | 2020-03-25 | Veracyte, Inc. | Verfahren zur bewertung eines copd-status |
| US11976329B2 (en) | 2013-03-15 | 2024-05-07 | Veracyte, Inc. | Methods and systems for detecting usual interstitial pneumonia |
| EP2986762B1 (de) | 2013-04-19 | 2019-11-06 | Bio-Rad Laboratories, Inc. | Digitale analyse von analyten |
| WO2015042454A1 (en) * | 2013-09-20 | 2015-03-26 | Integrated Diagnostics, Inc. | Compositions, methods and kits for diagnosis of lung cancer |
| US11901041B2 (en) | 2013-10-04 | 2024-02-13 | Bio-Rad Laboratories, Inc. | Digital analysis of nucleic acid modification |
| US9944977B2 (en) | 2013-12-12 | 2018-04-17 | Raindance Technologies, Inc. | Distinguishing rare variations in a nucleic acid sequence from a sample |
| US11193176B2 (en) | 2013-12-31 | 2021-12-07 | Bio-Rad Laboratories, Inc. | Method for detecting and quantifying latent retroviral RNA species |
| US9594085B2 (en) | 2014-02-03 | 2017-03-14 | Integrated Diagnostics, Inc. | Integrated quantification method for protein measurements in clinical proteomics |
| US12297505B2 (en) | 2014-07-14 | 2025-05-13 | Veracyte, Inc. | Algorithms for disease diagnostics |
| EP3215170A4 (de) | 2014-11-05 | 2018-04-25 | Veracyte, Inc. | Systeme und verfahren zur diagnose von idiopathischer pulmonaler fibrose auf transbronchialen biopsien mit maschinellem lernen und hochdimensionalen transkriptionsdaten |
| CN105154542B (zh) * | 2015-09-01 | 2018-04-17 | 杭州源清生物科技有限公司 | 一组用于肺癌分子分型的基因及其应用 |
| US10647981B1 (en) | 2015-09-08 | 2020-05-12 | Bio-Rad Laboratories, Inc. | Nucleic acid library generation methods and compositions |
| EP4180531A3 (de) | 2016-05-12 | 2023-08-23 | Trustees of Boston University | Genexpressionssignatur des nasenepithels und klassifikator zur vorhersage von lungenkrebs |
| US10927417B2 (en) | 2016-07-08 | 2021-02-23 | Trustees Of Boston University | Gene expression-based biomarker for the detection and monitoring of bronchial premalignant lesions |
| US10998178B2 (en) | 2017-08-28 | 2021-05-04 | Purdue Research Foundation | Systems and methods for sample analysis using swabs |
| JP2022527972A (ja) * | 2019-04-02 | 2022-06-07 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | 前悪性病変を有する患者において癌を予測及び予防する方法 |
| CN116144778A (zh) * | 2023-02-16 | 2023-05-23 | 广东省人民医院 | 利用肠道菌区分晚期突变型和野生型非小细胞肺癌的方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4445990A (en) * | 1981-11-12 | 1984-05-01 | General Electric Company | Electrolytic reactor for cleaning wastewater |
| US5763165A (en) * | 1994-03-10 | 1998-06-09 | Ludwig Institute For Cancer Research | Method for determining lung adenocarcinomas by assaying for one or more of MAGE-1, MAGE-2 and MAGE-3 |
| US6087102A (en) * | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
| WO1999050278A1 (en) * | 1998-03-31 | 1999-10-07 | Genzyme Corporation | Compositions and methods for the identification of lung tumor cells |
| WO1999060160A1 (en) | 1998-05-21 | 1999-11-25 | Diadexus Llc | A novel method of diagnosing, monitoring, and staging lung cancer |
| US20030065157A1 (en) * | 2001-04-04 | 2003-04-03 | Lasek Amy W. | Genes expressed in lung cancer |
| JP2005503145A (ja) * | 2001-08-16 | 2005-02-03 | ザ ユナイテッド ステイツ オブ アメリカ リプレゼンティッド バイ ザ シークレタリー デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 非小細胞肺癌の分子特性 |
| US20060151337A1 (en) * | 2005-01-07 | 2006-07-13 | Gilmore F W | Electrocoagulation Reaction Chamber |
-
2002
- 2002-08-16 JP JP2003520378A patent/JP2005503145A/ja active Pending
- 2002-08-16 CA CA002456334A patent/CA2456334A1/en not_active Abandoned
- 2002-08-16 AU AU2002355963A patent/AU2002355963A1/en not_active Abandoned
- 2002-08-16 EP EP02794901A patent/EP1453977B1/de not_active Expired - Lifetime
- 2002-08-16 US US10/486,844 patent/US7332590B2/en not_active Expired - Fee Related
- 2002-08-16 DE DE60234467T patent/DE60234467D1/de not_active Expired - Lifetime
- 2002-08-16 AT AT02794901T patent/ATE449187T1/de not_active IP Right Cessation
- 2002-08-16 WO PCT/US2002/026027 patent/WO2003015613A2/en not_active Ceased
-
2007
- 2007-07-27 US US11/829,483 patent/US7709202B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US7332590B2 (en) | 2008-02-19 |
| WO2003015613A3 (en) | 2004-06-24 |
| EP1453977A2 (de) | 2004-09-08 |
| EP1453977A4 (de) | 2005-04-20 |
| EP1453977B1 (de) | 2009-11-18 |
| WO2003015613A2 (en) | 2003-02-27 |
| US20090270265A1 (en) | 2009-10-29 |
| AU2002355963A1 (en) | 2003-03-03 |
| DE60234467D1 (de) | 2009-12-31 |
| JP2005503145A (ja) | 2005-02-03 |
| US7709202B2 (en) | 2010-05-04 |
| CA2456334A1 (en) | 2003-02-27 |
| US20050136403A1 (en) | 2005-06-23 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |