ATE449640T1 - Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membran - Google Patents

Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membran

Info

Publication number
ATE449640T1
ATE449640T1 AT01903969T AT01903969T ATE449640T1 AT E449640 T1 ATE449640 T1 AT E449640T1 AT 01903969 T AT01903969 T AT 01903969T AT 01903969 T AT01903969 T AT 01903969T AT E449640 T1 ATE449640 T1 AT E449640T1
Authority
AT
Austria
Prior art keywords
membrane
thrombogenic
plasma
producing
support
Prior art date
Application number
AT01903969T
Other languages
English (en)
Inventor
Thierry Crost
Jean-Louis Renaux
Michel Thomas
Original Assignee
Gambro Ind Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gambro Ind Sas filed Critical Gambro Ind Sas
Application granted granted Critical
Publication of ATE449640T1 publication Critical patent/ATE449640T1/de

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D67/00—Processes specially adapted for manufacturing semi-permeable membranes for separation processes or apparatus
    • B01D67/0081—After-treatment of organic or inorganic membranes
    • B01D67/0093—Chemical modification
    • B01D67/00931—Chemical modification by introduction of specific groups after membrane formation, e.g. by grafting
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L33/00—Antithrombogenic treatment of surgical articles, e.g. sutures, catheters, prostheses, or of articles for the manipulation or conditioning of blood; Materials for such treatment
    • A61L33/0005—Use of materials characterised by their function or physical properties
    • A61L33/0011—Anticoagulant, e.g. heparin, platelet aggregation inhibitor, fibrinolytic agent, other than enzymes, attached to the substrate
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/0233—Manufacturing thereof forming the bundle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D65/00—Accessories or auxiliary operations, in general, for separation processes or apparatus using semi-permeable membranes
    • B01D65/02—Membrane cleaning or sterilisation ; Membrane regeneration
    • B01D65/022—Membrane sterilisation
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D71/00—Semi-permeable membranes for separation processes or apparatus characterised by the material; Manufacturing processes specially adapted therefor
    • B01D71/06—Organic material
    • B01D71/40—Polymers of unsaturated acids or derivatives thereof, e.g. salts, amides, imides, nitriles, anhydrides, esters
    • B01D71/42—Polymers of nitriles, e.g. polyacrylonitrile
    • B01D71/421—Polyacrylonitrile
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/16—Use of chemical agents
    • B01D2321/168—Use of other chemical agents
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2321/00—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling
    • B01D2321/34—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling by radiation
    • B01D2321/346—Details relating to membrane cleaning, regeneration, sterilization or to the prevention of fouling by radiation by gamma radiation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Manufacturing & Machinery (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Materials Engineering (AREA)
  • Transplantation (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
  • Materials For Medical Uses (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
AT01903969T 2000-01-27 2001-01-26 Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membran ATE449640T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0001065A FR2804328B1 (fr) 2000-01-27 2000-01-27 Membrane semi-permeable non thrombogene et procede de fabrication
PCT/FR2001/000248 WO2001054802A1 (fr) 2000-01-27 2001-01-26 Membrane semi-permeable non thrombogene et procede de fabrication

Publications (1)

Publication Number Publication Date
ATE449640T1 true ATE449640T1 (de) 2009-12-15

Family

ID=8846384

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01903969T ATE449640T1 (de) 2000-01-27 2001-01-26 Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membran

Country Status (10)

Country Link
US (1) US7056458B2 (de)
EP (1) EP1165214B1 (de)
JP (1) JP4234345B2 (de)
AT (1) ATE449640T1 (de)
AU (1) AU779469B2 (de)
CA (1) CA2368999C (de)
DE (1) DE60140588D1 (de)
ES (1) ES2337231T3 (de)
FR (1) FR2804328B1 (de)
WO (1) WO2001054802A1 (de)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2859114B1 (fr) * 2003-08-28 2005-10-14 Gambro Lundia Ab Dispositif de filtration comportant une membrane semi-permeable pour le traitement extracorporel du sang ou du plasma pour prevenir notamment l'activation retardee de la phase contact
US20050045554A1 (en) * 2003-08-28 2005-03-03 Gambro Lundia Ab Membrane unit element, semipermeable membrane, filtration device, and processes for manufacturing the same
WO2008045021A2 (en) * 2005-08-01 2008-04-17 Rensselaer Polytechnic Institute Blood compatible nanomaterials and methods of making and using the same
FR2902670B1 (fr) 2006-06-22 2009-04-24 Gambro Lundia Ab Utilisation d'une suspension pour traiter un support a usage medical, support a usage medical, echangeur et dispositif d'adsorption comprenant le support
DE102006044525B3 (de) * 2006-09-21 2008-01-31 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Verfahren zur Herstellung von gemeinsam bereitstellbaren flexiblen integrierten Schaltkreisen
JP5266856B2 (ja) * 2008-04-22 2013-08-21 富士ゼロックス株式会社 難燃剤、樹脂組成物、及び樹脂成形体
EP2177603A1 (de) 2008-09-25 2010-04-21 Gambro Lundia AB Vorrichtung für Nierenzellexpansion
EP2168668A1 (de) 2008-09-25 2010-03-31 Gambro Lundia AB Membran für Zellexpansion
EP2168666A1 (de) 2008-09-25 2010-03-31 Gambro Lundia AB Bestrahlte Membran für Zellexpansion
ATE545440T1 (de) 2008-09-25 2012-03-15 Gambro Lundia Ab Hybride biologische künstliche niere
HUE032005T2 (en) * 2009-05-15 2017-08-28 Interface Biologics Inc Antithrombotic hollow fiber membranes, embedded resin and blood tube
EP3095509A1 (de) 2015-05-18 2016-11-23 Defymed Funktionalisierte membrane für biokünstliche organe
EP3124099A1 (de) 2015-07-30 2017-02-01 Gambro Lundia AB Acrylnitril-basierte membran mit verbesserter leistung
CN105943497B (zh) * 2016-05-11 2019-09-10 中国人民解放军第三军医大学 一种自组装纳米止血剂、其制备方法及应用
EP3296010B1 (de) 2016-09-14 2023-04-26 Gambro Lundia AB Auf acrylonitril basierende membran mit niedriger thrombogenität
WO2018075663A1 (en) 2016-10-18 2018-04-26 Interface Biologics, Inc. Plasticized pvc admixtures with surface modifying macromolecules and articles made therefrom
CN109689188A (zh) 2016-11-29 2019-04-26 甘布罗伦迪亚股份公司 用于吸附细菌的膜
EP3388140A1 (de) 2017-04-10 2018-10-17 Gambro Lundia AB Extrakorporaler blutkreislauf
US10961340B2 (en) 2017-07-14 2021-03-30 Fresenius Medical Care Holdings, Inc. Method for providing surface modifying composition with improved byproduct removal
CN107929838B (zh) * 2017-11-15 2020-12-25 青岛市市立医院 用于肾脏内科的血液透析装置
WO2019139085A1 (ja) * 2018-01-10 2019-07-18 テルモ株式会社 人工肺の製造方法
EP3680005A1 (de) * 2019-01-10 2020-07-15 Gambro Lundia AB Membran mit immobilisiertem anticoagulans und verfahren zu ihrer herstellung
EP3981505B1 (de) 2020-10-12 2024-11-27 Gambro Lundia AB Membran mit immobilisiertem antikoagulans und verfahren zu ihrer herstellung
EP4201507A1 (de) 2021-12-21 2023-06-28 Gambro Lundia AB Verfahren zur erhöhung der selektivität einer membran
EP4201508A1 (de) 2021-12-21 2023-06-28 Gambro Lundia AB Membran mit coating aus polydopamin und chondroitin sowie verfahren zu deren herstellung

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749619A (en) * 1985-08-21 1988-06-07 Hospal Industrie Hollow fibre useful in blood treating processes
US4800016A (en) 1986-11-24 1989-01-24 The University Of Michigan Extracorporeal blood de-heparinization system
JPS63290573A (ja) 1987-03-13 1988-11-28 バクスター・インターナショナル・インコーポレイテッド ヘパリン緩放出用医療装置
DE3837298C1 (de) 1988-11-03 1990-03-29 Fresenius Ag, 6380 Bad Homburg, De
US5455040A (en) 1990-07-26 1995-10-03 Case Western Reserve University Anticoagulant plasma polymer-modified substrate
WO1993005825A1 (en) 1991-09-20 1993-04-01 Baxter International Inc. Processes for reducing the thrombogenicity of biomaterials
DE4230513C1 (de) 1992-09-11 1994-03-31 Fresenius Ag Vorrichtung zur Entfernung von Aluminiumionen aus Blut und Lösung zur Verwendung in der Vorrichtung
DE4240681C2 (de) 1992-12-03 1994-09-08 Fresenius Ag Vorrichtung zur Hämodialyse ohne Antikoagulation
NO931809L (no) * 1993-05-19 1994-11-21 Norsk Hydro As Hemofilter
US5421815A (en) 1993-12-14 1995-06-06 Nof Corporation Method for blood dialysis using anticoagulent composition
US5637081A (en) 1993-12-14 1997-06-10 Nof Corporation Anticoagulant composition for use in blood dialysis circuit
SI9400289A (en) 1994-07-13 1996-02-29 Ponikvar Jadranka Buturovic A method for preventing blood coagulation in a haemodialysis circuit or haemodialysis analogy procedure in the extra-body circuit.
US5801063A (en) 1995-05-09 1998-09-01 Grandics; Peter Device and process for the biospecific removal of heparin
US5820917A (en) 1995-06-07 1998-10-13 Medtronic, Inc. Blood-contacting medical device and method
US5672638A (en) 1995-08-22 1997-09-30 Medtronic, Inc. Biocompatability for solid surfaces
US5679659A (en) 1995-08-22 1997-10-21 Medtronic, Inc. Method for making heparinized biomaterials
US5767108A (en) 1995-08-22 1998-06-16 Medtronic, Inc. Method for making improved heparinized biomaterials
DE19533682A1 (de) 1995-09-12 1997-03-13 Biotronik Mess & Therapieg Verfahren zum Anlagern und Immobilisieren von Heparin auf anorganischen Substratoberflächen von kardiovaskulären Implantanten
EP0769503A3 (de) 1995-10-17 1997-10-08 Terumo Corp Heparinkomplex und medizinische Anordnung die solche Verbindung enthält
US6306165B1 (en) 1996-09-13 2001-10-23 Meadox Medicals ePTFE small caliber vascular grafts with significant patency enhancement via a surface coating which contains covalently bonded heparin
US5855618A (en) 1996-09-13 1999-01-05 Meadox Medicals, Inc. Polyurethanes grafted with polyethylene oxide chains containing covalently bonded heparin
FR2758990B1 (fr) * 1996-09-19 1999-05-28 Hospal Ind Appareil pour le traitement du sang par circulation extracorporelle et procede de fabrication
US5891196A (en) 1997-04-16 1999-04-06 Baxter International Inc. Method for actively binding heparin to crosslinked biological tissues
EP0878491A3 (de) 1997-05-15 2000-08-30 Degussa-Hüls Aktiengesellschaft Heparinanaloge Homo- oder Copolymere, ihre Herstellung und Verwendung
US5885609A (en) 1997-05-23 1999-03-23 Northeastern University Biocompatible articles and method for making same
AU8211398A (en) 1997-05-27 1998-12-30 Akzo Nobel N.V. Use of oligosaccharide for preventing blood clotting in extracorporeal blood circuits
FR2772639B1 (fr) * 1997-12-24 2000-02-04 Hospal Ind Utilisation d'un polymere neutre ou cationique pour prevenir l'activation de la phase contact du sang ou du plasma en contact avec une membrane semi-permeable

Also Published As

Publication number Publication date
AU3191301A (en) 2001-08-07
WO2001054802A1 (fr) 2001-08-02
ES2337231T3 (es) 2010-04-22
FR2804328B1 (fr) 2002-03-15
EP1165214B1 (de) 2009-11-25
CA2368999C (fr) 2009-09-15
US20030021826A1 (en) 2003-01-30
JP2003520656A (ja) 2003-07-08
AU779469B2 (en) 2005-01-27
US7056458B2 (en) 2006-06-06
EP1165214A1 (de) 2002-01-02
FR2804328A1 (fr) 2001-08-03
DE60140588D1 (de) 2010-01-07
CA2368999A1 (fr) 2001-08-02
JP4234345B2 (ja) 2009-03-04

Similar Documents

Publication Publication Date Title
DE60140588D1 (de) Verfahren zur herstellung einer teildurchlässigen nicht thrombogene membran
DE69009435D1 (de) Asymmetrische halbdurchlässige Membran zur Behandlung von biologischen Flüssigkeiten.
ES2035194T5 (es) Un procedimiento para fabricar membranas asimetricas de permeabilidad selectiva adecuadas para hemodialisis y las membranas asi preparadas.
ATE548097T1 (de) Poröse verbundmembran und herstellungsverfahren dafür
DE69842074D1 (de) Verfahren zur Herstellung von hochasymmetrischen Ultrafiltrationsmembranen
ATE359858T1 (de) Dialysatoren zur blutbehandlung sowie ihr herstellungsverfahren
ATE243538T1 (de) Neues verfahren zur herstellung von mitteln zur oberflächenbehandlung
ATE479492T1 (de) Verwendung einer geladenen porösen membran zur herstellung von weichwasser
BR9406410A (pt) Membrana modificada na superfície e processo de preparação de membranas poliméricas modificadas na superfície com grupos funcionais para imobilização de moléculas bioativas
DE60117794D1 (de) Verfahren zur herstellung einer bipolaren membrane und deren anwendung
EP0980685A3 (de) Flüssigkeit für die Peritonealdialyse und Verfahren zur kontinuierlichen rezirkulierenden Peritonealkialyse unter Verwendung derselben
DE3877440D1 (de) Mikroporoese asymmetrische polyamidmembranen.
DE3584562D1 (de) Verfahren zur herstellung von hohlfasern und ihre verwendung in membrantrennverfahren.
FR2575480B1 (fr) Membrane poreuse en resine fluoree et son procede de preparation
DE60336707D1 (de) Halar-membrane
DE69839622D1 (de) Verfahren zur Herstellung eines künstlichen Organs, Hohlfasermembran, und Hohlfaserdialysator
ES481130A1 (es) Procedimiento para la fabricacion de una membrana de diali- sis.
ATE166002T1 (de) Verfahren zur herstellung von stabilen umkehrosmose-membranen aus sulfonierten polyaryläthern
DE60236290D1 (de) Hohlfasermembran zur reinigung von blut
ES2047889T3 (es) Procedimiento de fabricacion de una membrana semipermeable sobre un soporte conductor poroso para electroforesis.
JP2016077570A (ja) 血液処理用分離膜及びその膜を組み込んだ血液処理器
ATE279975T1 (de) Oberflächenfunktionalisiertes mesoporöses material und verfahren zur herstellung
UA29462C2 (uk) Ацетатцелюлозна напівпроникна мембрана у вигляді порожнистого волокна (варіанти), спосіб виготовлення порожнистоволоконної напівпроникної ацетатцелюлозної мембрани (варіанти), гемодіалізатор з ацетатцелюлозними напівпроникними мембранами, прилад для обро
EP1134019A3 (de) Hohlfaser-Membranen und ihre Herstellung
Lee et al. Manufacturing and separation characteristics of hemodialysis membranes to improve toxin removal rate

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties