ATE449867T1 - Verfahren und reagens zur messung von cholesterin in lipoproteinen hoher dichte - Google Patents
Verfahren und reagens zur messung von cholesterin in lipoproteinen hoher dichteInfo
- Publication number
- ATE449867T1 ATE449867T1 AT03756656T AT03756656T ATE449867T1 AT E449867 T1 ATE449867 T1 AT E449867T1 AT 03756656 T AT03756656 T AT 03756656T AT 03756656 T AT03756656 T AT 03756656T AT E449867 T1 ATE449867 T1 AT E449867T1
- Authority
- AT
- Austria
- Prior art keywords
- cholesterol
- polyoxyethylene
- reagent
- high density
- sample
- Prior art date
Links
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title abstract 4
- 102000015779 HDL Lipoproteins Human genes 0.000 title abstract 2
- 108010010234 HDL Lipoproteins Proteins 0.000 title abstract 2
- 239000003153 chemical reaction reagent Substances 0.000 title abstract 2
- 235000012000 cholesterol Nutrition 0.000 title abstract 2
- -1 polyoxyethylene Polymers 0.000 abstract 4
- 229920003171 Poly (ethylene oxide) Polymers 0.000 abstract 3
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 abstract 2
- 108010055297 Sterol Esterase Proteins 0.000 abstract 2
- 102000000019 Sterol Esterase Human genes 0.000 abstract 2
- 239000005515 coenzyme Substances 0.000 abstract 2
- 239000004094 surface-active agent Substances 0.000 abstract 2
- 102000009027 Albumins Human genes 0.000 abstract 1
- 108010088751 Albumins Proteins 0.000 abstract 1
- 108010089254 Cholesterol oxidase Proteins 0.000 abstract 1
- 150000003973 alkyl amines Chemical class 0.000 abstract 1
- 239000012736 aqueous medium Substances 0.000 abstract 1
- 108010023417 cholesterol dehydrogenase Proteins 0.000 abstract 1
- 239000002736 nonionic surfactant Substances 0.000 abstract 1
- FURYAADUZGZUGQ-UHFFFAOYSA-N phenoxybenzene;sulfuric acid Chemical compound OS(O)(=O)=O.C=1C=CC=CC=1OC1=CC=CC=C1 FURYAADUZGZUGQ-UHFFFAOYSA-N 0.000 abstract 1
- 229920000447 polyanionic polymer Polymers 0.000 abstract 1
- 125000003367 polycyclic group Chemical group 0.000 abstract 1
- 108010085346 steroid delta-isomerase Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/60—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving cholesterol
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/92—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving lipids, e.g. cholesterol, lipoproteins, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B21/00—Thiazine dyes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
- C12Q1/44—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving esterase
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/90241—Oxidoreductases (1.) acting on single donors with incorporation of molecular oxygen, i.e. oxygenases (1.13)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/902—Oxidoreductases (1.)
- G01N2333/904—Oxidoreductases (1.) acting on CHOH groups as donors, e.g. glucose oxidase, lactate dehydrogenase (1.1)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/914—Hydrolases (3)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Genetics & Genomics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Cell Biology (AREA)
- Endocrinology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002301327 | 2002-10-16 | ||
| PCT/JP2003/013258 WO2004035816A1 (ja) | 2002-10-16 | 2003-10-16 | 高密度リポ蛋白中のコレステロールの測定方法および試薬 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE449867T1 true ATE449867T1 (de) | 2009-12-15 |
Family
ID=32105011
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03756656T ATE449867T1 (de) | 2002-10-16 | 2003-10-16 | Verfahren und reagens zur messung von cholesterin in lipoproteinen hoher dichte |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US7851174B2 (de) |
| EP (1) | EP1555326B1 (de) |
| JP (1) | JP4498143B2 (de) |
| KR (1) | KR101046898B1 (de) |
| CN (1) | CN100577812C (de) |
| AT (1) | ATE449867T1 (de) |
| AU (1) | AU2003301323A1 (de) |
| CA (1) | CA2502559C (de) |
| DE (1) | DE60330264D1 (de) |
| ES (1) | ES2335658T3 (de) |
| WO (1) | WO2004035816A1 (de) |
Families Citing this family (32)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004048605A1 (ja) | 2002-11-27 | 2004-06-10 | Daiichi Pure Chemicals Co., Ltd. | 特定リポ蛋白中の脂質測定法 |
| TWI372783B (en) * | 2005-04-27 | 2012-09-21 | Kyowa Medex Co Ltd | A process for measuring the cholesterol in high density lipoprotein |
| JP5042023B2 (ja) * | 2005-08-31 | 2012-10-03 | デンカ生研株式会社 | 小粒子低比重リポ蛋白の定量方法および定量キット |
| US9360432B2 (en) * | 2005-10-31 | 2016-06-07 | Kyowa Medex Co., Ltd. | Method for measuring triglyceride in low-density lipoprotein |
| GB0526051D0 (en) | 2005-12-21 | 2006-02-01 | Oxford Biosensors Ltd | Cholesterol sensor |
| JP5297637B2 (ja) * | 2007-11-28 | 2013-09-25 | 富士フイルム株式会社 | 高密度リポ蛋白コレステロールの測定方法 |
| JP5313537B2 (ja) | 2008-04-10 | 2013-10-09 | 富士フイルム株式会社 | 高密度リポ蛋白コレステロール測定用乾式分析素子 |
| WO2010055916A1 (ja) * | 2008-11-14 | 2010-05-20 | 協和メデックス株式会社 | 低密度リポ蛋白中のコレステロールの測定方法、測定用試薬及び測定用キット |
| JP5596964B2 (ja) * | 2008-12-02 | 2014-09-24 | 協和メデックス株式会社 | リポ蛋白中成分の分別定量用標準品の製造方法 |
| JP5813284B2 (ja) * | 2009-10-26 | 2015-11-17 | デンカ生研株式会社 | ＡｐｏＥ−ｃｏｎｔａｉｎｉｎｇＨＤＬ中コレステロールの測定方法 |
| WO2011136316A1 (ja) * | 2010-04-30 | 2011-11-03 | 協和メデックス株式会社 | 低密度リポ蛋白中のコレステロールの測定方法、測定用試薬及び測定用キット |
| US20130171674A1 (en) * | 2010-07-23 | 2013-07-04 | Denka Seiken Co., Ltd. | Method for quantifying the amount of cholesterol in high-density lipoprotein 3 |
| US8617005B2 (en) | 2010-08-05 | 2013-12-31 | Active Mind Technologies R&D Limited | Golf data collection |
| BR112013001400A2 (pt) * | 2010-08-11 | 2016-05-24 | Kyowa Medex Co Ltd | método para conservar uma solução aquosa contendo um leuco-cromogênico, método para estabilizar um leuco-cromogênio, e, reagente líquido |
| JP4638555B1 (ja) * | 2010-09-08 | 2011-02-23 | 田中貴金属工業株式会社 | 核酸又は免疫クロマトグラフィー用試薬組成物、核酸又は免疫クロマトグラフィー測定方法及び核酸又は免疫クロマトグラフィー測定用キット |
| US9080201B2 (en) | 2011-03-16 | 2015-07-14 | Kyowa Medex Co., Ltd. | Method for measuring cholesterol in HDL subfraction, and reagents and kit therefor |
| CN110042146B (zh) | 2011-11-11 | 2023-09-01 | 雅培快速诊断国际无限公司 | 血样本的化验方法 |
| JP6047778B2 (ja) * | 2012-01-12 | 2016-12-21 | 株式会社シノテスト | 測定対象物質の測定方法及び測定試薬、並びにビリルビンに由来する影響の回避方法 |
| EP2891718B1 (de) * | 2012-08-31 | 2019-01-30 | Kyowa Medex Co., Ltd. | Verfahren zur messung von cholesterin in hochdichtem lipoprotein |
| JP6182008B2 (ja) * | 2013-07-24 | 2017-08-16 | デンカ生研株式会社 | 高密度リポタンパク質３中のコレステロールの定量方法及び定量試薬 |
| US20160208311A1 (en) | 2013-08-30 | 2016-07-21 | Sekisui Medical Co., Ltd. | Method for measuring cholesterol in high-density lipoprotein, and reagent for use in said method |
| JP6795887B2 (ja) * | 2013-11-21 | 2020-12-02 | 日立化成ダイアグノスティックス・システムズ株式会社 | 血清又は血漿中の高密度リポ蛋白の安定化剤及び安定化方法 |
| CN104076158B (zh) * | 2014-07-10 | 2016-08-17 | 深圳市新产业生物医学工程股份有限公司 | 一种用于测定高密度脂蛋白胆固醇的试剂盒 |
| US20170010290A1 (en) * | 2015-07-07 | 2017-01-12 | Mohmed E. Ashmaig | Methods of determining a high density lipoprotein phospholipid level in a sample |
| JP2017000152A (ja) * | 2016-07-14 | 2017-01-05 | 株式会社シノテスト | 測定対象物質の測定方法、測定対象物質の測定試薬、及びビリルビンに由来する影響の回避方法 |
| JP2017060522A (ja) * | 2016-12-20 | 2017-03-30 | デンカ生研株式会社 | 高密度リポ蛋白（ｈｄｌ）中のコレステロールの定量方法 |
| JP7651260B2 (ja) * | 2017-09-01 | 2025-03-26 | キヤノンメディカルダイアグノスティックス株式会社 | 低密度リポ蛋白中のコレステロールの測定方法、測定用試薬及び測定用キット |
| US11030225B2 (en) | 2018-01-24 | 2021-06-08 | Game Your Game, Inc. | Golf course management tool |
| CN109799356A (zh) * | 2018-12-28 | 2019-05-24 | 上海高踪医疗器械科技有限公司 | 一种测定高密度脂蛋白胆固醇的试剂盒及方法 |
| JP7455674B2 (ja) * | 2020-06-02 | 2024-03-26 | デンカ株式会社 | キットおよび方法 |
| CN112710656B (zh) * | 2020-12-23 | 2022-03-22 | 中生北控生物科技股份有限公司 | 一种测定葡萄糖含量的试剂盒及其应用 |
| CN115980372A (zh) * | 2022-12-29 | 2023-04-18 | 东软威特曼生物科技(南京)有限公司 | 一种高特异性的高密度脂蛋白peg-硫酸环糊精体系添加剂 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3117455A1 (de) * | 1981-05-02 | 1982-11-25 | Boehringer Mannheim Gmbh | Reagens zur praezipitation apo-b-haltiger lipoproteine, verfahren zu dessen herstellung und dessen verwendung bei der bestimmung von hdl-cholesterin |
| DE3533288A1 (de) * | 1985-09-18 | 1987-03-26 | Boehringer Mannheim Gmbh | Verfahren und reagenz zur spezifischen bestimmung von hdl-cholesterin im serum |
| DE3636851A1 (de) * | 1986-10-29 | 1988-05-11 | Boehringer Mannheim Gmbh | Verfahren und reagenz zur spezifischen bestimmung des cholesterins der hdl-fraktion |
| JP2653755B2 (ja) * | 1994-03-08 | 1997-09-17 | 協和メデックス株式会社 | 高密度リポ蛋白中のコレステロールの定量法 |
| JP2600065B2 (ja) | 1994-03-08 | 1997-04-16 | 協和メデックス株式会社 | 高密度リポ蛋白中のコレステロールの定量法 |
| JPH08116996A (ja) | 1994-10-26 | 1996-05-14 | Toyobo Co Ltd | 血清または血漿中のｈｄｌ−コレステロールを測定する方法 |
| JP2799835B2 (ja) * | 1995-01-31 | 1998-09-21 | 第一化学薬品株式会社 | コレステロールの定量方法 |
| JP3614514B2 (ja) | 1995-06-21 | 2005-01-26 | 国際試薬株式会社 | 高比重リポ蛋白分画中のコレステロールの定量方法及び定量用試薬キット |
| ES2165947T3 (es) * | 1995-07-21 | 2002-04-01 | Wako Pure Chem Ind Ltd | Metodo para medir la cantidad de un constituyente contenido en una lipoproteina especifica. |
| JPH09285298A (ja) | 1996-04-22 | 1997-11-04 | Iatron Lab Inc | Ｈｄｌ−コレステロールの測定方法及び測定用試薬 |
| JP3869471B2 (ja) * | 1996-04-22 | 2007-01-17 | 株式会社三菱化学ヤトロン | Ｈｄｌコレステロールの特異的測定方法及び測定用組成物 |
| ATE304608T1 (de) * | 1996-12-09 | 2005-09-15 | Denka Seiken Kk | Verfahren zur bestimmung des cholesteringehalts von high-density-lipoproteinen |
| JPH1156395A (ja) | 1997-08-27 | 1999-03-02 | Dai Ichi Pure Chem Co Ltd | コレステロールの定量法 |
| CA2344055C (en) * | 1998-09-18 | 2010-08-17 | Kyowa Medex Co., Ltd. | Method for fractional determination of cholesterol in lipoproteins and a reagent therefor |
| JP4547095B2 (ja) | 1999-03-01 | 2010-09-22 | シスメックス株式会社 | 生体試料成分の測定方法 |
| CA2366663A1 (en) | 1999-03-24 | 2000-09-28 | Mitsuaki Yamamoto | Method for quantitating cholesterol |
| CN1167809C (zh) * | 1999-06-21 | 2004-09-22 | 第一化学药品株式会社 | 以游离型胆固醇为底物的酶的反应促进物质 |
| JP4542234B2 (ja) * | 1999-06-21 | 2010-09-08 | 積水メディカル株式会社 | コレステロール定量用試料の前処理方法およびこれを利用する特定のリポ蛋白中のコレステロール定量法 |
| JP3686326B2 (ja) * | 2000-11-08 | 2005-08-24 | アークレイ株式会社 | 高密度リポタンパク質（ｈｄｌ）コレステロール測定用試験片 |
| JP3844058B2 (ja) * | 2000-11-14 | 2006-11-08 | 第一化学薬品株式会社 | 脂質測定方法およびそれに用いる試薬 |
| MXPA03004206A (es) * | 2000-11-14 | 2003-09-22 | Daiichi Pure Chemicals Co Ltd | Metodo de ensayo de lipido y reactivo para su uso en el mismo. |
-
2003
- 2003-10-16 EP EP03756656A patent/EP1555326B1/de not_active Expired - Lifetime
- 2003-10-16 CA CA2502559A patent/CA2502559C/en not_active Expired - Lifetime
- 2003-10-16 WO PCT/JP2003/013258 patent/WO2004035816A1/ja not_active Ceased
- 2003-10-16 CN CN200380100779A patent/CN100577812C/zh not_active Expired - Lifetime
- 2003-10-16 ES ES03756656T patent/ES2335658T3/es not_active Expired - Lifetime
- 2003-10-16 DE DE60330264T patent/DE60330264D1/de not_active Expired - Lifetime
- 2003-10-16 US US10/531,315 patent/US7851174B2/en not_active Expired - Lifetime
- 2003-10-16 JP JP2004544971A patent/JP4498143B2/ja not_active Expired - Lifetime
- 2003-10-16 KR KR1020057006643A patent/KR101046898B1/ko not_active Expired - Lifetime
- 2003-10-16 AT AT03756656T patent/ATE449867T1/de not_active IP Right Cessation
- 2003-10-16 AU AU2003301323A patent/AU2003301323A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP4498143B2 (ja) | 2010-07-07 |
| EP1555326A4 (de) | 2006-10-04 |
| CA2502559C (en) | 2014-12-16 |
| CA2502559A1 (en) | 2004-04-29 |
| EP1555326A1 (de) | 2005-07-20 |
| KR20050052542A (ko) | 2005-06-02 |
| US7851174B2 (en) | 2010-12-14 |
| US20060014229A1 (en) | 2006-01-19 |
| CN1694965A (zh) | 2005-11-09 |
| KR101046898B1 (ko) | 2011-07-06 |
| AU2003301323A1 (en) | 2004-05-04 |
| ES2335658T3 (es) | 2010-03-31 |
| JPWO2004035816A1 (ja) | 2006-02-16 |
| DE60330264D1 (de) | 2010-01-07 |
| WO2004035816A1 (ja) | 2004-04-29 |
| CN100577812C (zh) | 2010-01-06 |
| EP1555326B1 (de) | 2009-11-25 |
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