ATE450273T1 - Proliferationshemmendes arzneimittel - Google Patents
Proliferationshemmendes arzneimittelInfo
- Publication number
- ATE450273T1 ATE450273T1 AT06763171T AT06763171T ATE450273T1 AT E450273 T1 ATE450273 T1 AT E450273T1 AT 06763171 T AT06763171 T AT 06763171T AT 06763171 T AT06763171 T AT 06763171T AT E450273 T1 ATE450273 T1 AT E450273T1
- Authority
- AT
- Austria
- Prior art keywords
- proliferation drug
- proliferation
- drug
- conjugates
- esterified
- Prior art date
Links
- 230000001028 anti-proliverative effect Effects 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 abstract 1
- 229920002674 hyaluronan Polymers 0.000 abstract 1
- 229960003160 hyaluronic acid Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IE20050328 | 2005-05-18 | ||
| PCT/EP2006/062388 WO2006122954A2 (en) | 2005-05-18 | 2006-05-17 | Antiproliferative conjugates comprising hyaluronic acid and n-derivatives of glutamic acid |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE450273T1 true ATE450273T1 (de) | 2009-12-15 |
Family
ID=37027872
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06763171T ATE450273T1 (de) | 2005-05-18 | 2006-05-17 | Proliferationshemmendes arzneimittel |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US20080200428A1 (de) |
| EP (1) | EP1888069B1 (de) |
| JP (1) | JP2008540790A (de) |
| CN (1) | CN101227906A (de) |
| AT (1) | ATE450273T1 (de) |
| AU (1) | AU2006248966A1 (de) |
| CA (1) | CA2609069A1 (de) |
| DE (1) | DE602006010852D1 (de) |
| ES (1) | ES2337726T3 (de) |
| WO (1) | WO2006122954A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5001645B2 (ja) * | 2004-04-02 | 2012-08-15 | 電気化学工業株式会社 | ヒアルロン酸−メトトレキサート結合体 |
| IE20060049A1 (en) * | 2006-01-25 | 2007-08-08 | Eurand Pharmaceuticals Ltd | A novel drug delivery system: use of hyaluronic acid as a carrier moleclue for different classes of therapeutic active agents |
| IE20070900A1 (en) * | 2007-12-12 | 2009-06-24 | Eurand Pharmaceuticals Ltd | New anticancer conjugates |
| ITMI20072416A1 (it) * | 2007-12-21 | 2009-06-22 | Sigea Srl | Derivati polisaccaridici dell'acido lipoico, loro preparazione ed uso come dermocosmetici e presidi medicali |
| TWI478943B (zh) * | 2012-12-27 | 2015-04-01 | Ind Tech Res Inst | 高分子組成物用於製備具有抑制基質金屬蛋白酶之活性的功效的醫療器材或抑制劑的用途 |
| EP3267975A4 (de) | 2015-03-09 | 2018-08-08 | The Regents of the University of California | Polymer-arzneimittel-konjugate zur kombinationstherapie gegen krebs |
| US20230102840A1 (en) * | 2020-06-23 | 2023-03-30 | President And Fellows Of Harvard College | Compositions and methods relating to combinatorial hyaluronic acid conjugates |
| CN117838875B (zh) * | 2020-07-15 | 2025-01-24 | 上海椿安生物医药科技有限公司 | 用于局部递送治疗剂的药物递送系统以及其用途 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4018181B2 (ja) * | 1995-11-07 | 2007-12-05 | 生化学工業株式会社 | グリコサミノグリカン誘導体およびその製造法 |
| IT1318403B1 (it) * | 2000-03-17 | 2003-08-25 | Cooperativa Ct Ricerche Poly T | Esteri polisaccaridici di n-derivati di acido glutammico. |
| US6673919B2 (en) * | 2001-03-30 | 2004-01-06 | Chisso Cororation | Chemically modified hyaluronic acid or salts thereof, and a process for producing thereof |
| JP2004018750A (ja) * | 2002-06-18 | 2004-01-22 | Seikagaku Kogyo Co Ltd | 親水性を向上したヒアルロン酸誘導体の製造方法 |
| CN101921347B (zh) * | 2004-01-07 | 2014-07-30 | 生化学工业株式会社 | 透明质酸衍生物及含有其的药剂 |
| JP4927536B2 (ja) * | 2004-03-05 | 2012-05-09 | 電気化学工業株式会社 | ヒアルロン酸−メトトレキサート結合体 |
-
2006
- 2006-05-17 WO PCT/EP2006/062388 patent/WO2006122954A2/en not_active Ceased
- 2006-05-17 DE DE602006010852T patent/DE602006010852D1/de not_active Expired - Lifetime
- 2006-05-17 AU AU2006248966A patent/AU2006248966A1/en not_active Abandoned
- 2006-05-17 AT AT06763171T patent/ATE450273T1/de not_active IP Right Cessation
- 2006-05-17 EP EP06763171A patent/EP1888069B1/de not_active Expired - Lifetime
- 2006-05-17 CA CA002609069A patent/CA2609069A1/en not_active Abandoned
- 2006-05-17 JP JP2008511702A patent/JP2008540790A/ja active Pending
- 2006-05-17 ES ES06763171T patent/ES2337726T3/es not_active Expired - Lifetime
- 2006-05-17 CN CNA2006800161505A patent/CN101227906A/zh active Pending
- 2006-05-17 US US11/914,671 patent/US20080200428A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ES2337726T3 (es) | 2010-04-28 |
| CN101227906A (zh) | 2008-07-23 |
| WO2006122954A2 (en) | 2006-11-23 |
| AU2006248966A1 (en) | 2006-11-23 |
| WO2006122954A3 (en) | 2007-03-15 |
| JP2008540790A (ja) | 2008-11-20 |
| US20080200428A1 (en) | 2008-08-21 |
| EP1888069B1 (de) | 2009-12-02 |
| EP1888069A2 (de) | 2008-02-20 |
| CA2609069A1 (en) | 2006-11-23 |
| DE602006010852D1 (de) | 2010-01-14 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |