ATE450516T1 - Phenylsulfamate als aromataseinhibitoren - Google Patents

Phenylsulfamate als aromataseinhibitoren

Info

Publication number
ATE450516T1
ATE450516T1 AT05747149T AT05747149T ATE450516T1 AT E450516 T1 ATE450516 T1 AT E450516T1 AT 05747149 T AT05747149 T AT 05747149T AT 05747149 T AT05747149 T AT 05747149T AT E450516 T1 ATE450516 T1 AT E450516T1
Authority
AT
Austria
Prior art keywords
phenylsulfamates
aromates
inhibitors
independently
hydrocarbyl
Prior art date
Application number
AT05747149T
Other languages
English (en)
Inventor
Lok Woo
Toby Jackson
Christian Bubert
Atul Purohit
Michael Reed
Barry Potter
Original Assignee
Sterix Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sterix Ltd filed Critical Sterix Ltd
Application granted granted Critical
Publication of ATE450516T1 publication Critical patent/ATE450516T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/04—Drugs for disorders of the muscular or neuromuscular system for myasthenia gravis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT05747149T 2004-06-04 2005-06-03 Phenylsulfamate als aromataseinhibitoren ATE450516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0412492.1A GB0412492D0 (en) 2004-06-04 2004-06-04 Compound
PCT/GB2005/002194 WO2005118560A1 (en) 2004-06-04 2005-06-03 Phenyl-sulfamates as aromatase inhibitors

Publications (1)

Publication Number Publication Date
ATE450516T1 true ATE450516T1 (de) 2009-12-15

Family

ID=32696670

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05747149T ATE450516T1 (de) 2004-06-04 2005-06-03 Phenylsulfamate als aromataseinhibitoren

Country Status (9)

Country Link
US (2) US7763642B2 (de)
EP (1) EP1753732B1 (de)
AT (1) ATE450516T1 (de)
DE (1) DE602005018049D1 (de)
DK (1) DK1753732T3 (de)
ES (1) ES2337804T3 (de)
GB (1) GB0412492D0 (de)
PL (1) PL1753732T3 (de)
WO (1) WO2005118560A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007012394A (es) 2005-04-06 2007-11-07 Sicor Inc Procesos para la preparacion de farmacos anticancer.
GB0525323D0 (en) * 2005-12-13 2006-01-18 Sterix Ltd Compound
US8093279B2 (en) 2005-12-13 2012-01-10 Gillian Reed, legal representative Compound
US20100204146A1 (en) 2007-09-17 2010-08-12 Preglem S.A. Treatment of Oestrogen Dependant Conditions in Pre-menopausal Women
US9682941B2 (en) 2013-12-31 2017-06-20 Estryx Pharma Limited Substituted biphenyl analogues as dual inhibitors of aromatase and sulfatase
EP3325482B1 (de) 2015-07-21 2020-06-24 ImmunoGen, Inc. Verfahren zur herstellung von zytotoxischen benzodiazepinderivaten

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8714013D0 (en) 1987-06-16 1987-07-22 Ici Plc (substituted-aralkyl)heterocyclic compounds
GB9003939D0 (en) 1990-02-21 1990-04-18 Imperial College Sulphatase inhibitors
GB9118478D0 (en) 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
GB9118465D0 (en) 1991-08-29 1991-10-16 Imperial College Steroid sulphatase inhibitors
GB9422777D0 (en) 1994-11-11 1995-01-04 Imperial College Assay
US5723315A (en) 1996-08-23 1998-03-03 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them
WO1998005635A1 (en) 1996-08-07 1998-02-12 Darwin Discovery Limited Hydroxamic and carboxylic acid derivatives having mmp and tnf inhibitory activity
EP2065396A1 (de) 1996-08-30 2009-06-03 Human Genome Sciences, Inc. Interleukin-19
US6126939A (en) 1996-09-03 2000-10-03 Yeda Research And Development Co. Ltd. Anti-inflammatory dipeptide and pharmaceutical composition thereof
ES2217428T3 (es) 1996-09-25 2004-11-01 Ss Pharmaceutical Co., Ltd. Derivados de vinilpiridina sustituidos y medicamentos que los contienen.
US6585954B1 (en) 1998-03-26 2003-07-01 Kyowa Hakko Kogyo Co., Ltd. Method for searching steroid sulfatase inhibitors
GB9807779D0 (en) 1998-04-09 1998-06-10 Ciba Geigy Ag Organic compounds
KR20020063888A (ko) * 1999-11-04 2002-08-05 바실리어 파마슈티카 아게 치환된 5-벤질-2,4-디아미노피리미딘
IL154920A0 (en) * 2000-09-22 2003-10-31 Bayer Cropscience Ag Delta 1-pyrrollines for use as pesticides
CA2464770C (en) * 2001-11-21 2011-08-16 Sterix Limited Compound
GB0525323D0 (en) * 2005-12-13 2006-01-18 Sterix Ltd Compound

Also Published As

Publication number Publication date
WO2005118560A1 (en) 2005-12-15
US20070117855A1 (en) 2007-05-24
EP1753732A1 (de) 2007-02-21
ES2337804T3 (es) 2010-04-29
GB0412492D0 (en) 2004-07-07
DE602005018049D1 (en) 2010-01-14
US20110021586A1 (en) 2011-01-27
US8470860B2 (en) 2013-06-25
US7763642B2 (en) 2010-07-27
DK1753732T3 (da) 2010-04-12
EP1753732B1 (de) 2009-12-02
PL1753732T3 (pl) 2010-05-31

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties