ATE450549T1 - Monoklonale antikörper mit spezifität für fetale erythroidzellen - Google Patents

Monoklonale antikörper mit spezifität für fetale erythroidzellen

Info

Publication number
ATE450549T1
ATE450549T1 AT05736009T AT05736009T ATE450549T1 AT E450549 T1 ATE450549 T1 AT E450549T1 AT 05736009 T AT05736009 T AT 05736009T AT 05736009 T AT05736009 T AT 05736009T AT E450549 T1 ATE450549 T1 AT E450549T1
Authority
AT
Austria
Prior art keywords
specificity
cells
monoclonal antibodies
erythroid cells
fetal
Prior art date
Application number
AT05736009T
Other languages
English (en)
Inventor
Christiane Hollmann
Silke Zimmermann
Stefan Stachelhaus
Winfried Albert
Original Assignee
Adnagen Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Adnagen Ag filed Critical Adnagen Ag
Application granted granted Critical
Publication of ATE450549T1 publication Critical patent/ATE450549T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966Animal cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/577Immunoassay; Biospecific binding assay; Materials therefor involving monoclonal antibodies binding reaction mechanisms characterised by the use of monoclonal antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/10Immunoglobulins specific features characterized by their source of isolation or production
    • C07K2317/14Specific host cells or culture conditions, e.g. components, pH or temperature
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70582CD71
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2469/00Immunoassays for the detection of microorganisms
    • G01N2469/10Detection of antigens from microorganism in sample from host
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125Digestion or removing interfering materials
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25375Liberation or purification of sample or separation of material from a sample [e.g., filtering, centrifuging, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ecology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
AT05736009T 2004-03-31 2005-03-31 Monoklonale antikörper mit spezifität für fetale erythroidzellen ATE450549T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04007811 2004-03-31
PCT/EP2005/003371 WO2005100401A2 (en) 2004-03-31 2005-03-31 Monoclonal antibodies with specificity for fetal erythroid cells

Publications (1)

Publication Number Publication Date
ATE450549T1 true ATE450549T1 (de) 2009-12-15

Family

ID=35150543

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05736009T ATE450549T1 (de) 2004-03-31 2005-03-31 Monoklonale antikörper mit spezifität für fetale erythroidzellen

Country Status (9)

Country Link
US (6) US7858757B2 (de)
EP (1) EP1732951B1 (de)
JP (1) JP4756032B2 (de)
AT (1) ATE450549T1 (de)
AU (1) AU2005233254B2 (de)
CA (1) CA2561830C (de)
DE (1) DE602005018028D1 (de)
ES (1) ES2337702T3 (de)
WO (1) WO2005100401A2 (de)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2561830C (en) * 2004-03-31 2013-05-21 Adnagen Ag Monoclonal antibodies with specificity for fetal erythroid cells
US11111544B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US9424392B2 (en) 2005-11-26 2016-08-23 Natera, Inc. System and method for cleaning noisy genetic data from target individuals using genetic data from genetically related individuals
US11111543B2 (en) 2005-07-29 2021-09-07 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
US10081839B2 (en) 2005-07-29 2018-09-25 Natera, Inc System and method for cleaning noisy genetic data and determining chromosome copy number
US10083273B2 (en) 2005-07-29 2018-09-25 Natera, Inc. System and method for cleaning noisy genetic data and determining chromosome copy number
DE102006062619B4 (de) * 2006-12-29 2012-04-26 Medion Diagnostics Ag Verfahren zur Bestimmung von minoren Zellpopulationen in heterogenen Zellpopulationen
EP2321642B1 (de) 2008-08-04 2017-01-11 Natera, Inc. Verfahren für allelzuordnung und ploidiezuordnung
WO2011041485A1 (en) 2009-09-30 2011-04-07 Gene Security Network, Inc. Methods for non-invasive prenatal ploidy calling
US11339429B2 (en) 2010-05-18 2022-05-24 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11322224B2 (en) 2010-05-18 2022-05-03 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11408031B2 (en) 2010-05-18 2022-08-09 Natera, Inc. Methods for non-invasive prenatal paternity testing
US11332785B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US11939634B2 (en) 2010-05-18 2024-03-26 Natera, Inc. Methods for simultaneous amplification of target loci
US20190010543A1 (en) 2010-05-18 2019-01-10 Natera, Inc. Methods for simultaneous amplification of target loci
US12152275B2 (en) 2010-05-18 2024-11-26 Natera, Inc. Methods for non-invasive prenatal ploidy calling
US9677118B2 (en) 2014-04-21 2017-06-13 Natera, Inc. Methods for simultaneous amplification of target loci
US12221653B2 (en) 2010-05-18 2025-02-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11332793B2 (en) 2010-05-18 2022-05-17 Natera, Inc. Methods for simultaneous amplification of target loci
WO2011146632A1 (en) 2010-05-18 2011-11-24 Gene Security Network Inc. Methods for non-invasive prenatal ploidy calling
US10316362B2 (en) 2010-05-18 2019-06-11 Natera, Inc. Methods for simultaneous amplification of target loci
US11326208B2 (en) 2010-05-18 2022-05-10 Natera, Inc. Methods for nested PCR amplification of cell-free DNA
CA2818173C (en) 2010-11-30 2022-05-03 Genentech, Inc. Low affinity blood brain barrier receptor antibodies and uses therefor
CN103608466B (zh) 2010-12-22 2020-09-18 纳特拉公司 非侵入性产前亲子鉴定方法
RU2671980C2 (ru) 2011-02-09 2018-11-08 Натера, Инк. Способы неинвазивного пренатального установления плоидности
US9174216B2 (en) 2013-03-13 2015-11-03 DeNovo Science, Inc. System for capturing and analyzing cells
US9404864B2 (en) 2013-03-13 2016-08-02 Denovo Sciences, Inc. System for imaging captured cells
US10466160B2 (en) 2011-08-01 2019-11-05 Celsee Diagnostics, Inc. System and method for retrieving and analyzing particles
CN103998394B (zh) 2011-08-01 2016-08-17 德诺弗科学公司 细胞捕获系统和使用方法
US20130122492A1 (en) 2011-11-14 2013-05-16 Kellbenx Inc. Detection, isolation and analysis of rare cells in biological fluids
CA2876692C (en) 2012-06-22 2022-05-24 Quantrx Biomedical Corporation Method for obtaining fetal cells and fetal cellular components
US20140100126A1 (en) 2012-08-17 2014-04-10 Natera, Inc. Method for Non-Invasive Prenatal Testing Using Parental Mosaicism Data
US9752181B2 (en) 2013-01-26 2017-09-05 Denovo Sciences, Inc. System and method for capturing and analyzing cells
US9707562B2 (en) 2013-03-13 2017-07-18 Denovo Sciences, Inc. System for capturing and analyzing cells
US10391490B2 (en) 2013-05-31 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
US9856535B2 (en) 2013-05-31 2018-01-02 Denovo Sciences, Inc. System for isolating cells
US9499870B2 (en) 2013-09-27 2016-11-22 Natera, Inc. Cell free DNA diagnostic testing standards
US10577655B2 (en) 2013-09-27 2020-03-03 Natera, Inc. Cell free DNA diagnostic testing standards
US10262755B2 (en) 2014-04-21 2019-04-16 Natera, Inc. Detecting cancer mutations and aneuploidy in chromosomal segments
CA2945962C (en) 2014-04-21 2023-08-29 Natera, Inc. Detecting mutations and ploidy in chromosomal segments
JP2017521091A (ja) * 2014-05-15 2017-08-03 ケルベンクス インコーポレイテッド 診断試験用の胎児有核赤血球(nrbc)の調製
US20160130553A1 (en) * 2014-05-15 2016-05-12 Kellbenx Incorporated PREPARATION OF FETAL NUCLEATED RED BLOOD CELLS (NRBCs) FOR DIAGNOSTIC TESTING
US20180173846A1 (en) 2014-06-05 2018-06-21 Natera, Inc. Systems and Methods for Detection of Aneuploidy
EP3179248A4 (de) * 2014-08-05 2017-06-14 Fujifilm Corporation Verfahren zur trennung von nukleierten roten blutkörperchen
US12202890B1 (en) 2014-11-07 2025-01-21 Kellbenx Incorporated Antibodies for detection and enrichment of fetal cells and their use
US11479812B2 (en) 2015-05-11 2022-10-25 Natera, Inc. Methods and compositions for determining ploidy
RU2760913C2 (ru) 2016-04-15 2021-12-01 Натера, Инк. Способы выявления рака легкого
WO2018067517A1 (en) 2016-10-04 2018-04-12 Natera, Inc. Methods for characterizing copy number variation using proximity-litigation sequencing
GB201618485D0 (en) 2016-11-02 2016-12-14 Ucl Business Plc Method of detecting tumour recurrence
US10011870B2 (en) 2016-12-07 2018-07-03 Natera, Inc. Compositions and methods for identifying nucleic acid molecules
JP6234542B1 (ja) 2016-12-27 2017-11-22 株式会社 TL Genomics 胎児細胞由来染色体dnaの取得方法
WO2018156418A1 (en) 2017-02-21 2018-08-30 Natera, Inc. Compositions, methods, and kits for isolating nucleic acids
US10391492B2 (en) 2017-08-29 2019-08-27 Celsee Diagnostics, Inc. System and method for isolating and analyzing cells
CA3076601C (en) 2017-10-19 2022-08-16 Tl Genomics Inc. Chip for cell classification
US12084720B2 (en) 2017-12-14 2024-09-10 Natera, Inc. Assessing graft suitability for transplantation
US10946380B2 (en) * 2018-01-19 2021-03-16 International Business Machines Corporation Microfluidic chips for particle purification and fractionation
US12398389B2 (en) 2018-02-15 2025-08-26 Natera, Inc. Methods for isolating nucleic acids with size selection
US12024738B2 (en) 2018-04-14 2024-07-02 Natera, Inc. Methods for cancer detection and monitoring
US12234509B2 (en) 2018-07-03 2025-02-25 Natera, Inc. Methods for detection of donor-derived cell-free DNA
US10633693B1 (en) 2019-04-16 2020-04-28 Celsee Diagnostics, Inc. System and method for leakage control in a particle capture system
WO2020223596A1 (en) 2019-05-02 2020-11-05 Kellbenx Incorporated Filtration-based methods for preparing fetal nucleated red blood cells (nrbcs) for diagnostic testing
AU2020267743B2 (en) 2019-05-07 2023-04-06 Bio-Rad Laboratories, Inc. System and method for automated single cell processing
US11273439B2 (en) 2019-05-07 2022-03-15 Bio-Rad Laboratories, Inc. System and method for target material retrieval from microwells
US12305235B2 (en) 2019-06-06 2025-05-20 Natera, Inc. Methods for detecting immune cell DNA and monitoring immune system
WO2020251802A1 (en) 2019-06-14 2020-12-17 Bio-Rad Laboratories, Inc. System and method for automated single cell processing and analyses
US11504719B2 (en) 2020-03-12 2022-11-22 Bio-Rad Laboratories, Inc. System and method for receiving and delivering a fluid for sample processing
WO2023034409A1 (en) 2021-09-01 2023-03-09 Biogen Ma Inc. Anti-transferrin receptor antibodies and uses thereof
CN118369438A (zh) 2021-12-10 2024-07-19 伯乐实验室有限公司 用形态可调节功能化颗粒进行样品处理的组合物、方法和系统
CN115861769B (zh) * 2022-12-23 2026-02-03 正泰集团研发中心(上海)有限公司 塑壳缺陷检测模型的训练方法、塑壳缺陷检测方法及装置

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10035433C2 (de) * 2000-07-20 2002-07-18 Tuma Wolfgang Schonende Hochanreicherung von fetalen Zellen aus pripherem Blut und Verwendung derselben
ITRM20010322A1 (it) 2001-06-08 2002-12-09 Consiglio Nazionale Ricerche Metodo non ivasivo su sangue materno per lo screening e la diagnosi di aneuploidie fetali.
CA2561830C (en) * 2004-03-31 2013-05-21 Adnagen Ag Monoclonal antibodies with specificity for fetal erythroid cells

Also Published As

Publication number Publication date
WO2005100401A2 (en) 2005-10-27
US20230324383A1 (en) 2023-10-12
US20140154704A1 (en) 2014-06-05
US20110129916A1 (en) 2011-06-02
US20160039932A1 (en) 2016-02-11
EP1732951B1 (de) 2009-12-02
US8536312B2 (en) 2013-09-17
AU2005233254A1 (en) 2005-10-27
US9453841B2 (en) 2016-09-27
US20070275418A1 (en) 2007-11-29
DE602005018028D1 (de) 2010-01-14
ES2337702T3 (es) 2010-04-28
US7858757B2 (en) 2010-12-28
CA2561830A1 (en) 2005-10-27
US20160084837A1 (en) 2016-03-24
US9194871B2 (en) 2015-11-24
CA2561830C (en) 2013-05-21
JP4756032B2 (ja) 2011-08-24
WO2005100401A3 (en) 2006-06-15
JP2007530629A (ja) 2007-11-01
EP1732951A2 (de) 2006-12-20
AU2005233254B2 (en) 2011-11-24

Similar Documents

Publication Publication Date Title
ATE450549T1 (de) Monoklonale antikörper mit spezifität für fetale erythroidzellen
ATE528648T1 (de) Verfahren zum nachweis antikörper-herstellender zellen
NZ623706A (en) Anti-il-17a/il-17f cross-reactive antibodies and methods of use thereof
PT1308507E (pt) Anticorpo monoclonal anti-núcleo de hcv
ATE468355T1 (de) Diabody-typ bispezifischer antikörper
MY171554A (en) Monoclonal antibody and immunoassay using the same
TW200616662A (en) Humanized anti-5t4 antibodies and anti-5t4 antibody/calicheamicin conjugates
EA200971114A1 (ru) Определение антигенов, расположенных на эритроцитах, и антиэритроцитарных антител
WO2008122793A3 (en) Blood group antibody screening
ATE464374T1 (de) Assay zum schnellen nachweis vom humanen aktivierten protein c und hochspezifischer monoklonaler antikörper dagegen
EP4527465A3 (de) Anti-glypican-3-antikörper
WO2008025964A3 (en) Antibodies to an epitope of agr2. assays and hybridomas
EP1072888A3 (de) Immunoassay-Verfahren und -Reagens für HIV-1p24-Antigen
TW200740842A (en) Monoclonal antibodies, hybridoma cell lines, methods and kits for detecting phytase
AU2003283240A8 (en) Antibody for isolating and/or identifying mesenchymal stem cells and method for isolating and/or identifying mesenchymal stem cells
WO2010053772A3 (en) Disease-associated antigens and methods of use thereof
WO2006020263A3 (en) Cytoxan antibodies and immunoassay
WO2006075142A3 (en) FORMS OF FACTOR XIIa
WO2005114203A3 (en) Dominant b cell epitopes and methods of making and using thereof
EP1879029A4 (de) Immunnachweiskit in verbindung mit neuroglobin-enzym sowie verwendung davon
EP1359161A3 (de) Monoklonaler Antikörper, der spezifische gegen tartratbeständige Säurephosphatase 5b gerichtet ist und dessen Verwendung
MX2022014580A (es) Ensayo de multiplex doble para multiples isotipos de inmunoglobulina.
WO2007011698A3 (en) Humanized antibody conjugates and related methods, assays, reagents, and kits
RU2005115525A (ru) Штамм культивируемых клеток мышиной гибридомы а3, используемый для получения моноклональных антител к антигену ядрышек клеток человека
BR0204612A (pt) Anticorpos monoclonais antinúcleo de hcv

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1732951

Country of ref document: EP