ATE451445T1 - Verfahren und vorrichtungen zur entfernung von psoralenen aus blutprodukten. - Google Patents

Verfahren und vorrichtungen zur entfernung von psoralenen aus blutprodukten.

Info

Publication number
ATE451445T1
ATE451445T1 AT96921456T AT96921456T ATE451445T1 AT E451445 T1 ATE451445 T1 AT E451445T1 AT 96921456 T AT96921456 T AT 96921456T AT 96921456 T AT96921456 T AT 96921456T AT E451445 T1 ATE451445 T1 AT E451445T1
Authority
AT
Austria
Prior art keywords
devices
removal
blood products
methods
psoralen
Prior art date
Application number
AT96921456T
Other languages
English (en)
Inventor
Derek Hei
Original Assignee
Cerus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cerus Corp filed Critical Cerus Corp
Priority claimed from US08/659,249 external-priority patent/US6544727B1/en
Application granted granted Critical
Publication of ATE451445T1 publication Critical patent/ATE451445T1/de

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/12Layered products comprising a layer of synthetic resin next to a fibrous or filamentary layer
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/16Blood plasma; Blood serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14Blood; Artificial blood
    • A61K35/19Platelets; Megacaryocytes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/10Inactivation or decontamination of a medicinal preparation prior to administration to an animal or a person
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Disinfection or sterilisation of materials or objects, in general; Accessories therefor
    • A61L2/02Disinfection or sterilisation of materials or objects, in general; Accessories therefor using physical processes
    • A61L2/08Radiation
    • A61L2/081Gamma radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3681Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation
    • A61M1/3683Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents
    • A61M1/3686Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by irradiation using photoactive agents by removing photoactive agents after irradiation
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B27/00Layered products comprising a layer of synthetic resin
    • B32B27/36Layered products comprising a layer of synthetic resin comprising polyesters
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B5/00Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts
    • B32B5/02Layered products characterised by the non- homogeneity or physical structure, i.e. comprising a fibrous, filamentary, particulate or foam layer; Layered products characterised by having a layer differing constitutionally or physically in different parts characterised by structural features of a fibrous or filamentary layer
    • B32B5/028Net structure, e.g. spaced apart filaments bonded at the crossing points
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2103/00Materials or objects being the target of disinfection or sterilisation
    • A61L2103/05Living organisms or biological materials
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2367/00Polyesters, e.g. PET, i.e. polyethylene terephthalate
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B32LAYERED PRODUCTS
    • B32BLAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
    • B32B2439/00Containers; Receptacles
    • B32B2439/80Medical packaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Anesthesiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Zoology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • External Artificial Organs (AREA)
  • Compounds Of Unknown Constitution (AREA)
AT96921456T 1995-06-07 1996-06-07 Verfahren und vorrichtungen zur entfernung von psoralenen aus blutprodukten. ATE451445T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48492695A 1995-06-07 1995-06-07
US66091096A 1996-06-07 1996-06-07
PCT/US1996/009846 WO1996040857A1 (en) 1995-06-07 1996-06-07 Methods and devices for the removal of psoralens from blood products
US08/659,249 US6544727B1 (en) 1995-06-07 1996-06-07 Methods and devices for the removal of psoralens from blood products

Publications (1)

Publication Number Publication Date
ATE451445T1 true ATE451445T1 (de) 2009-12-15

Family

ID=29740870

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96921456T ATE451445T1 (de) 1995-06-07 1996-06-07 Verfahren und vorrichtungen zur entfernung von psoralenen aus blutprodukten.

Country Status (8)

Country Link
EP (1) EP0840781B1 (de)
JP (1) JP4968974B2 (de)
AT (1) ATE451445T1 (de)
AU (1) AU6267796A (de)
CA (1) CA2221605C (de)
DE (1) DE69638094D1 (de)
ES (1) ES2337852T3 (de)
WO (1) WO1996040857A1 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009051846A (ja) * 1995-06-07 2009-03-12 Cerus Corp 血液製剤からソラレンを除去するための方法およびデバイス
WO1996039818A1 (en) * 1995-06-07 1996-12-19 Cerus Corporation Treating red blood cell solutions with anti-viral agents
DE19544297A1 (de) * 1995-11-28 1997-06-05 Behringwerke Ag Verfahren zur Entfernung von aromatischen Verbindungen aus produkthaltigen Lösungen
AU714882B2 (en) * 1996-04-09 2000-01-13 Therakos, Inc. Method for removal of psoralens from biological fluids
US6514987B1 (en) 1997-01-06 2003-02-04 Cerus Corporation Frangible compounds for pathogen inactivation
US20010009756A1 (en) 1998-01-06 2001-07-26 Derek Hei Flow devices for the reduction of compounds from biological compositions and methods of use
US6093725A (en) * 1997-01-06 2000-07-25 Cerus Corporation Frangible compounds for pathogen inactivation
US20010018179A1 (en) 1998-01-06 2001-08-30 Derek J. Hei Batch devices for the reduction of compounds from biological compositions containing cells and methods of use
CA2276747C (en) * 1997-01-06 2004-04-13 Cerus Corporation Methods and devices for the reduction of small organic compounds from blood products
DE69826521T2 (de) 1998-01-06 2005-09-29 Cerus Corp., Concord Verfahren zum quenchen von pathogen-inaktivatoren in biologischen materialien
US7611831B2 (en) 1998-01-06 2009-11-03 Cerus Corporation Adsorbing pathogen-inactivating compounds with porous particles immobilized in a matrix
US6617100B2 (en) * 1998-09-25 2003-09-09 V.I. Technologies, Inc. Solid phase quenching systems
US6403359B1 (en) 1998-09-25 2002-06-11 V. I. TECHNOLOGIES, Inc. Solid phase quenching systems
US7068361B2 (en) 1999-06-03 2006-06-27 Baxter International Apparatus, systems and methods for processing and treating a biological fluid with light
US7445756B2 (en) 1999-06-03 2008-11-04 Fenwal, Inc. Fluid processing sets and organizers for the same
US6364864B1 (en) 1999-06-03 2002-04-02 Baxter International Inc. Plastic containers having inner pouches and methods for making such containers
US6565802B1 (en) 1999-06-03 2003-05-20 Baxter International Inc. Apparatus, systems and methods for processing and treating a biological fluid with light
US7025877B1 (en) * 1999-06-03 2006-04-11 Baxter International Inc. Processing set for processing and treating a biological fluid
AU2005265960B8 (en) * 2004-06-29 2012-01-12 Reliance Life Sciences Pvt Ltd Process for improvement of virus-safe biological fluids
CN101094692A (zh) 2004-10-29 2007-12-26 塞鲁斯公司 用于红细胞灭活过程的改进的猝灭方法
AU2006325531B2 (en) 2005-12-13 2012-04-19 Exthera Medical Corporation Method for extracorporeal removal of a pathogenic microbe, an inflammatory cell or an inflammatory protein from blood
JP5231246B2 (ja) 2006-01-05 2013-07-10 サン−ゴバン パフォーマンス プラスティックス コーポレイション 環状シールおよび環状シールを含むポンプ
WO2007082110A1 (en) 2006-01-05 2007-07-19 Saint-Gobain Performance Plastics Corporation Composite material and seals formed thereof
SG189745A1 (en) 2008-04-09 2013-05-31 Cerus Corp Improved quenching methods for red blood cell pathogen inactivation
DE202008012267U1 (de) * 2008-09-16 2009-02-05 KBD Gesellschaft für Unternehmensberatung, Marketing und Vertrieb mbH i. Gr. Vorrichtung zum visuellen Erkennen der Verteilung von lumineszierenden Substanzen
EP2358790B2 (de) 2008-12-16 2016-09-21 Dow Corning Corporation Herstellung von siloxanen
US8349959B2 (en) 2008-12-24 2013-01-08 Saint-Gobain Performance Plastics Corporation Polymer material and seals formed thereof for high pressure pump applications
WO2011049709A1 (en) 2009-10-23 2011-04-28 Fenwal, Inc. Methods and systems for providing red blood cell products with reduced plasma
ES2861359T3 (es) 2009-12-01 2021-10-06 Exthera Medical Corp Dispositivo para eliminar citoquinas de la sangre con polisacáridos inmovilizados en superficie
WO2012112724A1 (en) 2011-02-15 2012-08-23 Exthera Medical, Llc Device and method for removal of blood-borne pathogens, toxins and inflammatory cytokines
ES2647577T3 (es) 2012-06-13 2017-12-22 Exthera Medical Corporation Uso de heparina y carbohidratos para tratar el cáncer
US9295393B2 (en) 2012-11-09 2016-03-29 Elwha Llc Embolism deflector
US20140158604A1 (en) * 2012-12-12 2014-06-12 Jacques Chammas Platelet Storage Container
JP6648009B2 (ja) 2013-06-24 2020-02-14 エクステラ・メディカル・コーポレーション マンノース被覆基材を含有する血液濾過システム
WO2015005961A1 (en) 2013-07-12 2015-01-15 Emd Millipore Corporation A method of determining virus removal from a sample containing a target protein using activated carbon
AU2014346668C1 (en) 2013-11-08 2018-04-26 Exthera Medical Corporation Methods for diagnosing infectious diseases using adsorption media
DE15782250T1 (de) 2014-04-24 2017-08-10 Exthera Medical Corporation Verfahren zur Entfernung von Bakterien aus Blut unter Verwendung einer hohen Durchflussrate
WO2016014854A1 (en) 2014-07-23 2016-01-28 Cerus Corporation Methods for preparing platelet products
CN106714669B (zh) * 2014-09-22 2021-05-14 艾克塞拉医疗公司 可穿戴的血液灌流装置
WO2016057965A1 (en) 2014-10-10 2016-04-14 Cerus Corporation Compositions and methods for treating viral hemorrhagic fever
WO2016210374A1 (en) 2015-06-26 2016-12-29 Cerus Corporation Cryoprecipitate compositions and methods of preparation thereof
US20170028121A1 (en) * 2015-07-31 2017-02-02 Fenwal, Inc. Irradiation device for biological fluids
EP3364986B1 (de) 2015-10-23 2023-12-13 Cerus Corporation Pathogen-inaktiviertes kryoarmes plasma und verfahren zur verwendung davon
EP3399986B1 (de) 2016-01-07 2023-02-22 Cerus Corporation Systeme und verfahren zur herstellung von plättchen
US11911551B2 (en) 2016-03-02 2024-02-27 Exthera Medical Corporation Method for treating drug intoxication
EP3422943A4 (de) 2016-03-02 2019-10-16 ExThera Medical Corporation Verfahren zur behandlung von arzneimittelintoxikation
CN110573169B (zh) 2017-03-03 2024-10-01 塞鲁斯公司 制备病原体灭活的血小板组合物的试剂盒和方法
SG11202002438TA (en) 2017-09-20 2020-04-29 Cerus Corp Compositions and methods for pathogen inactivation of platelets
CN116571191A (zh) 2017-12-29 2023-08-11 塞鲁斯公司 用于处理生物流体的系统和方法
EP3969014A4 (de) 2019-05-16 2023-01-25 ExThera Medical Corporation Verfahren zur modulation der endothelialen glycocalyxstruktur
CN114173842A (zh) 2019-06-22 2022-03-11 塞鲁斯公司 生物流体处理系统
JP7571063B2 (ja) 2019-06-22 2024-10-22 シーラス コーポレイション 生物学的流体の処理を実施するシステム及び方法
WO2020264421A1 (en) 2019-06-28 2020-12-30 Cerus Corporation System and methods for implementing a biological fluid treatment device
US20260034277A1 (en) 2024-06-20 2026-02-05 Cerus Corporation Systems and methods for pathogen inactivation of blood products

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756082A (fr) * 1969-09-12 1971-03-11 I Elementoorganiche Kih Soedin Squelettes macroreticulaires de polystyrene pour resines echangeuses d'ions et leur procede de preparation (
US4748120A (en) * 1983-05-02 1988-05-31 Diamond Scientific Co. Photochemical decontamination treatment of whole blood or blood components
DE3819000A1 (de) * 1988-06-03 1989-12-14 Hasso Von Bluecher Beutel in der art eines teebeutels zur beseitigung von schadstoffen
US5094960A (en) * 1988-10-07 1992-03-10 New York Blood Center, Inc. Removal of process chemicals from labile biological mixtures by hydrophobic interaction chromatography
US5418130A (en) * 1990-04-16 1995-05-23 Cryopharm Corporation Method of inactivation of viral and bacterial blood contaminants
US5176634A (en) * 1990-08-02 1993-01-05 Mcgaw, Inc. Flexible multiple compartment drug container
US5209347A (en) * 1990-12-05 1993-05-11 Clintec Nutrition Company Internal tear seal dual bag
US5128048A (en) * 1991-05-22 1992-07-07 Baxter International Inc. Systems and methods for removing undesired matter from blood cells
JPH09500015A (ja) * 1993-06-23 1997-01-07 ニューヨーク ブラッド センター,インコーポレイティド 血液のウィルス不活性化のためのシステム
US5399719A (en) * 1993-06-28 1995-03-21 Steritech, Inc. Compounds for the photodecontamination of pathogens in blood
US6319662B1 (en) * 1993-12-17 2001-11-20 Baxter International Inc. Method and apparatus for removing viral contaminants from a body fluid

Also Published As

Publication number Publication date
JP2002509518A (ja) 2002-03-26
CA2221605C (en) 2005-10-18
CA2221605A1 (en) 1996-12-19
DE69638094D1 (de) 2010-01-21
WO1996040857A1 (en) 1996-12-19
ES2337852T3 (es) 2010-04-29
AU6267796A (en) 1996-12-30
JP4968974B2 (ja) 2012-07-04
EP0840781A1 (de) 1998-05-13
EP0840781A4 (de) 2001-03-21
EP0840781B1 (de) 2009-12-09

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