ATE45148T1 - Pyrazol-verbindungen. - Google Patents

Pyrazol-verbindungen.

Info

Publication number: ATE45148T1
Authority: AT; Austria
Prior art keywords: pyrazole compounds; useful; prevent; pyrazole; compounds inhibit
Prior art date: 1984-06-18

Application number

AT85304237T

Other languages

English (en)

Inventor

Kenneth Steven Hirsch

Charles David Jones

Harold Mellon Taylor

Original Assignee

Lilly Co Eli

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-06-18

Filing date

1985-06-14

Publication date

1989-08-15

1985-06-14 Application filed by Lilly Co Eli filed Critical Lilly Co Eli

1989-08-15 Application granted granted Critical

1989-08-15 Publication of ATE45148T1 publication Critical patent/ATE45148T1/de

Links

WTKZEGDFNFYCGP-UHFFFAOYSA-N Pyrazole Chemical class C=1C=NNC=1 WTKZEGDFNFYCGP-UHFFFAOYSA-N 0.000 title 1
102000014654 Aromatase Human genes 0.000 abstract 1
108010078554 Aromatase Proteins 0.000 abstract 1
230000001419 dependent effect Effects 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
229940011871 estrogen Drugs 0.000 abstract 1
239000000262 estrogen Substances 0.000 abstract 1
150000003217 pyrazoles Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

AT85304237T 1984-06-18 1985-06-14 Pyrazol-verbindungen. ATE45148T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US06/621,598 US4609666A (en)	1984-06-18	1984-06-18	Aromatase inhibiting derivatives of α,α-bis(4-halophenyl)methyltetrazoles and triazoles
EP85304237A EP0165782B1 (de)	1984-06-18	1985-06-14	Pyrazol-Verbindungen

Publications (1)

Publication Number	Publication Date
ATE45148T1 true ATE45148T1 (de)	1989-08-15

Family

ID=24490838

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT85304237T ATE45148T1 (de)	1984-06-18	1985-06-14	Pyrazol-verbindungen.

Country Status (6)

Country	Link
US (1)	US4609666A (de)
EP (1)	EP0165782B1 (de)
JP (1)	JPH0625132B2 (de)
AT (1)	ATE45148T1 (de)
CA (1)	CA1266665A (de)
DE (1)	DE3571976D1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4937250A (en) *	1988-03-07	1990-06-26	Ciba-Geigy Corporation	Alpha-heterocycle substituted tolunitriles
IE59813B1 (en) *	1986-05-09	1994-04-06	Warner Lambert Co	Styryl pyrazoles, isoxazoles and analogs thereof having activity as 5-lipoxy-genase inhibitors and pharmaceutical compositions containing them
GB8614712D0 (en) *	1986-06-17	1986-07-23	Ici Plc	Heterocyclic compounds
NZ224714A (en) *	1987-06-01	1990-03-27	Janssen Pharmaceutica Nv	Substituted benzotriazole derivatives and pharmaceutical compositions
US5039677A (en) *	1987-06-01	1991-08-13	Janssen Pharmaceutica N.V.	6-(1H-azol-1-ylmethyl)-1-(pyrimidinyloxy)-1H benzotriazoles
US4943574A (en) *	1987-06-01	1990-07-24	Janssen Pharmaceutica N.V.	(1H-azol-1-ylmethyl) substituted benzotriazole derivatives and pharmaceutical compositions containing them
DE3926365A1 (de) *	1989-08-04	1991-02-07	Schering Ag	Cycloalkylenazole, verfahren zu deren herstellung, pharmazeutische praeparate, die diese enthalten sowie ihre verwendung zur herstellung von arzneimitteln
TW210334B (de) *	1990-12-12	1993-08-01	Ciba Geigy Ag
ES2139605T3 (es) *	1991-09-02	2000-02-16	Yamanouchi Pharma Co Ltd	Amina terciaria triazolilada o una sal de esta.

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3123615A (en) *		1964-03-03		Oxyphenyl
US3155666A (en) *	1963-07-18	1964-11-03	Searle & Co	1-dialkylaminoalkyl-5-diphenylmethyl-1h-tetrazoles and related compounds
BR6915465D0 (pt) *	1969-03-07	1973-01-04	Bayer Ag	Processo para preparar n-benzimidazois substituidos na posicao alfa por heterociclos penta-membrados com atividade antimicotica
BE756663A (fr) *	1969-09-27	1971-03-25	Bayer Ag	Composition destinee a la regulation de la croissance des vegetaux
DE2009020C3 (de) *	1970-02-26	1979-09-13	Bayer Ag, 5090 Leverkusen	Verfahren zur Herstellung von N-(l,l,l-trisubstituierten)-Methylazolen
US3764690A (en) *	1972-03-03	1973-10-09	Bayer Ag	Substituted n-benzylimidazoles as antimycotic agents
US4235893A (en) *	1978-05-08	1980-11-25	Brodie Angela M	Ester derivatives of 4-hydroxy-4-androstene-3,17-dione and a method for inhibiting estrogen biosynthesis
DE3129193A1 (de) *	1981-07-24	1983-02-03	Hoechst Ag, 6000 Frankfurt	Azolderivate, verfahren zu ihrer herstellung und ihre verwendung als schaedlingsbekaempfungsmittel

1984
- 1984-06-18 US US06/621,598 patent/US4609666A/en not_active Expired - Fee Related
1985
- 1985-06-11 CA CA000483670A patent/CA1266665A/en not_active Expired - Lifetime
- 1985-06-14 DE DE8585304237T patent/DE3571976D1/de not_active Expired
- 1985-06-14 AT AT85304237T patent/ATE45148T1/de not_active IP Right Cessation
- 1985-06-14 EP EP85304237A patent/EP0165782B1/de not_active Expired
- 1985-06-18 JP JP60135229A patent/JPH0625132B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
JPS6112668A (ja)	1986-01-21
CA1266665A (en)	1990-03-13
DE3571976D1 (de)	1989-09-07
US4609666A (en)	1986-09-02
EP0165782A1 (de)	1985-12-27
EP0165782B1 (de)	1989-08-02
JPH0625132B2 (ja)	1994-04-06

Legal Events

Date	Code	Title	Description
1990-01-15	UEP	Publication of translation of european patent specification
1998-03-15	REN	Ceased due to non-payment of the annual fee

Publication	Publication Date	Title
NL930005I2 (nl)	1993-09-16	17 Beta-gesubstitueerde-4-aza-5alfa-androstenonen en gebruik ervan als inhibitoren van 5alfa-reduct ase.
FR2571966B1 (fr)	1988-04-15	Compositions therapeutiques contenant des anthracyclines-glucosides.
DK169685A (da)	1985-10-17	Aktibakterielle midler
DE3583779D1 (de)	1991-09-19	Gelzusammensetzungen von liposomen.
MY104685A (en)	1994-05-31	Substituted thiazoles and their use as fungicides.
ATE58900T1 (de)	1990-12-15	Diaryldiazolylmethane.
FI871570A0 (fi)	1987-04-09	Utmatningsanordning foer en fraon en rulle avdragbar materialbana.
DE3576328D1 (de)	1990-04-12	Behandlung feuerfester gegenstaende.
DE3874073D1 (de)	1992-10-01	Aromatasehemmende 4(5)-imidazole.
ATE65994T1 (de)	1991-08-15	Insektentoetende pyrazoline.
DE3583857D1 (de)	1991-09-26	Kobaltborat-katalysierte zersetzung von organischen hydroperoxyden.
DE3477786D1 (de)	1989-05-24	Fungicidal imidazoles and triazoles
DE3869007D1 (de)	1992-04-16	Oxydation von alkanen.
DE3670310D1 (de)	1990-05-17	Elektrochemische behandlung von ligninen.
ATE45148T1 (de)	1989-08-15	Pyrazol-verbindungen.
ATE40822T1 (de)	1989-03-15	Aromatase-hemmende 1,2,3-triazol-1-yl-, tetrazol- 1-yl- und tetrazol-2-yl-verbindungen.
FI850285A7 (fi)	1985-07-27	Triatsolien ja oligoeetterien ryhmiin kuuluvat fungisidit.
ATE9156T1 (de)	1984-09-15	Therapeutische zusammenstellungen von imidazolpyridinen.
ATE37714T1 (de)	1988-10-15	Imidazolyl-, triazolyl- und tetrazolylverbindungen.
DK148585D0 (da)	1985-04-01	Imidazolderivater
MA20366A1 (fr)	1985-10-01	Concentrees emulsionnables contenant des azoles
ATE48132T1 (de)	1989-12-15	Isoxazol- und isothiazolderivate.
DE3583063D1 (de)	1991-07-11	Elektrochemische reduktion von cyanpyridin-basen.
RO91593A (ro)	1987-07-30	Compozitie fungicida solida
ATE109150T1 (de)	1994-08-15	Mono- und diepoxid-derivate von ll-f28249- verbindungen.