ATE452121T1 - Casr-antagonist - Google Patents

Casr-antagonist

Info

Publication number
ATE452121T1
ATE452121T1 AT04729243T AT04729243T ATE452121T1 AT E452121 T1 ATE452121 T1 AT E452121T1 AT 04729243 T AT04729243 T AT 04729243T AT 04729243 T AT04729243 T AT 04729243T AT E452121 T1 ATE452121 T1 AT E452121T1
Authority
AT
Austria
Prior art keywords
casr antagonist
casr
antagonist
Prior art date
Application number
AT04729243T
Other languages
English (en)
Inventor
Yuko Shinagawa
Teruhiko Inoue
Toshihiro Kiguchi
Taku Ikenogami
Naoki Ogawa
Kenji Fukuda
Takashi Nakagawa
Masanori Shindo
Yuki Soejima
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Application granted granted Critical
Publication of ATE452121T1 publication Critical patent/ATE452121T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
    • C07C323/62—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/02—Systems containing only non-condensed rings with a three-membered ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Endocrinology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Furan Compounds (AREA)
AT04729243T 2003-04-23 2004-04-23 Casr-antagonist ATE452121T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2003119131 2003-04-23
PCT/JP2004/005886 WO2004094362A1 (ja) 2003-04-23 2004-04-23 CaSRアンタゴニスト

Publications (1)

Publication Number Publication Date
ATE452121T1 true ATE452121T1 (de) 2010-01-15

Family

ID=33308093

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04729243T ATE452121T1 (de) 2003-04-23 2004-04-23 Casr-antagonist

Country Status (30)

Country Link
US (4) US7304174B2 (de)
EP (3) EP2308828A3 (de)
JP (1) JP3751312B2 (de)
KR (1) KR100696927B1 (de)
CN (2) CN101723921A (de)
AR (1) AR044075A1 (de)
AT (1) ATE452121T1 (de)
AU (1) AU2004232604C1 (de)
BR (1) BRPI0407097A (de)
CA (1) CA2513738C (de)
CL (1) CL2004000868A1 (de)
CO (1) CO5640091A2 (de)
CY (1) CY1109880T1 (de)
DE (1) DE602004024668D1 (de)
DK (1) DK1619180T3 (de)
ES (1) ES2337576T3 (de)
HR (1) HRP20100042T1 (de)
IL (1) IL169575A (de)
MX (1) MXPA05007609A (de)
MY (1) MY138734A (de)
NO (1) NO20054868L (de)
NZ (1) NZ541188A (de)
PE (1) PE20050460A1 (de)
PL (1) PL1619180T3 (de)
PT (1) PT1619180E (de)
RU (1) RU2315036C2 (de)
SI (1) SI1619180T1 (de)
TW (1) TWI329628B (de)
WO (1) WO2004094362A1 (de)
ZA (1) ZA200505587B (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0302094D0 (en) 2003-01-29 2003-02-26 Pharmagene Lab Ltd EP4 receptor antagonists
EP1630157A4 (de) * 2003-05-28 2007-05-23 Japan Tobacco Inc Casr-antagonist
GB0324269D0 (en) 2003-10-16 2003-11-19 Pharmagene Lab Ltd EP4 receptor antagonists
US20070155819A1 (en) * 2004-02-06 2007-07-05 Marquis Robert W Jr Calcilytic compounds
EP2010150A2 (de) * 2006-04-20 2009-01-07 Amgen Inc. Stabile emulsionsformulierungen
CA2681582C (en) 2007-03-30 2015-07-14 Amgen Inc. Methods of treating bowel disorders
CN102056897B (zh) 2008-06-05 2014-05-07 旭化成制药株式会社 磺酰胺化合物及其用途
NZ593676A (en) * 2008-12-24 2012-06-29 Daiichi Sankyo Co Ltd Calcium-sensing receptor antagonists
CN102307852B (zh) 2008-12-24 2013-12-18 第一三共株式会社 环状胺化合物
WO2010103429A1 (en) * 2009-03-10 2010-09-16 Pfizer Inc. 1,1-(Dimethyl-Ethylamino)-2-Hydroxy-Propoxy]-Ethyl}-3-Methyl-Biphenyl-4- Carboxylic Acid Derivatives As Calcium Receptor Antagonists
WO2010104882A1 (en) 2009-03-10 2010-09-16 Amgen Inc. Methods of modulating sperm motility
NZ595513A (en) * 2009-03-26 2013-05-31 Japan Tobacco Inc Process for producing carboxylic acid compound
WO2010113860A1 (ja) * 2009-03-31 2010-10-07 第一三共株式会社 ビフェニル－環状アミン化合物
EP2435400A2 (de) 2009-05-27 2012-04-04 Leo Pharma A/S Neue, den calcium sensing receptor modulierende verbindungen und deren pharmazeutische verwendung
US8765676B2 (en) 2009-05-27 2014-07-01 Leo Pharma A/S Calcium sensing receptor modulating compounds and pharmaceutical use thereof
WO2012069420A2 (en) 2010-11-26 2012-05-31 Leo Pharma A/S Calcium-sensing receptor-active compounds
JP2014508103A (ja) 2010-11-26 2014-04-03 レオ ファーマ アクティーゼルスカブ カルシウム感知受容体活性化合物
EP2643292A1 (de) 2010-11-26 2013-10-02 Leo Pharma A/S Casr-aktive verbindungen
JP2014500882A (ja) 2010-11-26 2014-01-16 レオ ファーマ アクティーゼルスカブ カルシウム感知受容体活性化合物
GB201113538D0 (en) * 2011-08-04 2011-09-21 Karobio Ab Novel estrogen receptor ligands
JP2015528462A (ja) * 2012-08-27 2015-09-28 ルピン・リミテッドＬｕｐｉｎ Ｌｉｍｉｔｅｄ カルシウム感知受容体モジュレーターとしてのアリールアルキルアミン化合物
EP3468550A4 (de) 2016-06-13 2020-02-12 Syneurx International (Taiwan) Corp. Verwendung von lithiumbenzoat zur behandlung von störungen des zentralen nervensystems
WO2021115272A1 (zh) * 2019-12-09 2021-06-17 北京拓界生物医药科技有限公司 钙敏感受体激动剂化合物及其应用
KR20230106582A (ko) * 2020-08-04 2023-07-13 캘시리틱스 테라퓨틱스, 인코포레이티드 트리페닐 칼실리틱 화합물의 제형
AU2021343475A1 (en) * 2020-09-18 2023-06-01 Calcilytix Therapeutics, Inc. Triphenyl calcilytic compounds for the treatment of autosomal dominant hypocalcemia type 1 (adh1)
EP4698162A1 (de) 2023-04-21 2026-02-25 Calcilytix Therapeutics, Inc. Behandlung von hypoparathyroidismus unter verwendung von triphenylcalcilytischen verbindungen

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE633760A (de) * 1963-06-18
DD207203A1 (de) * 1982-06-21 1984-02-22 Peter Meisel Verfahren zur herstellung von epoxypropylethern
DE3743265A1 (de) * 1987-12-19 1989-06-29 Boehringer Ingelheim Kg Neue ammoniumverbindungen, ihre herstellung und verwendung
US5276008A (en) * 1990-08-09 1994-01-04 Bayer Aktiengesellschaft Substituted 4,5-diamino-1,2,4-triazol-3-(thi)ones
ATE313321T1 (de) * 1991-08-23 2006-01-15 Nps Pharma Inc Kalzium-rezeptor aktive verbindungen
US6818660B2 (en) 1996-04-09 2004-11-16 Nps Pharmaceuticals, Inc. Calcilytic compounds
DE69733649T2 (de) * 1996-04-09 2006-05-18 NPS Pharmaceuticals, Inc., Salt Lake City Calcylitische verbindungen
ES2171839T3 (es) * 1996-09-05 2002-09-16 Lilly Co Eli Analogos de carbazol como agonistas adrenergicos selectivos de beta3.
UY24949A1 (es) 1997-04-08 2001-04-30 Smithkline Beecham Corp Compuestos calcilíticos
US20020052509A1 (en) 1998-04-08 2002-05-02 Smithkline Beecham Corporation Calcilytic compounds and method of use
AR014975A1 (es) 1998-04-08 2001-04-11 Nps Pharma Inc Compuestos calciliticos, una composicion farmaceutica que los comprende, y el uso de los mismos para la fabricacion de un medicamento
PE20000415A1 (es) 1998-04-08 2000-05-21 Smithkline Beecham Corp Compuestos calciliticos
US6334338B1 (en) * 1998-07-02 2002-01-01 Lucent Technologies Inc. Sol gel process of making a fiber preform with removal of oxide particles
CA2340341A1 (en) 1998-08-12 2000-02-24 Smithkline Beecham Corporation Calcilytic compounds
EP1112073A4 (de) 1998-08-12 2002-10-25 Smithkline Beecham Corp Calcilytische verbindungen
HK1041483B (zh) * 1998-10-23 2004-12-24 霍夫曼-拉罗奇有限公司 雙環氮雜環
PE20001456A1 (es) 1999-02-02 2001-01-28 Smithkline Beecham Corp Compuestos calcioliticos
AU7072200A (en) * 1999-08-27 2001-03-26 Procter & Gamble Company, The Fast-acting formulation components, compositions and laundry methods employing same
IL139073A0 (en) 1999-10-21 2001-11-25 Pfizer Treatment of neuropathy
US20030018203A1 (en) * 2002-07-17 2003-01-23 Largo Maria Amparo Calcilytic compounds
AR030684A1 (es) 2000-01-24 2003-09-03 Smithkline Beecham Corp Compuestos calciliticos, uso de dichos compuestos en la manufactura de medicamentos, e intermediarios utiles en la preparacion de dichos compuestos
US6867299B2 (en) * 2000-02-24 2005-03-15 Hoffmann-La Roche Inc. Oxamide IMPDH inhibitors
ES2296774T3 (es) 2000-07-21 2008-05-01 Smithkline Beecham Corporation Compuestos calcioliticos.
ATE411275T1 (de) * 2000-08-11 2008-10-15 Japan Tobacco Inc Calciumrezeptor-antagonisten
WO2002038106A2 (en) 2000-10-25 2002-05-16 Smithkline Beecham Corporation Calcilytic compounds
ES2273909T3 (es) 2000-10-25 2007-05-16 Smithkline Beecham Corporation Compuestos calciliticos.
AR038658A1 (es) 2001-06-15 2005-01-26 Novartis Ag Derivados de 4-aril-2(1h) quinazolinona y 4-aril-quinazolina 2-sustituidas, un proceso para su preparacion, composiciones farmaceuticas y el uso de dichos derivados para la preparacion de un medicamento
US6864267B2 (en) 2001-07-16 2005-03-08 Smithkline Beecham Corporation Calcilytic compounds
EP1630157A4 (de) * 2003-05-28 2007-05-23 Japan Tobacco Inc Casr-antagonist

Also Published As

Publication number Publication date
CN1741984A (zh) 2006-03-01
CN100577633C (zh) 2010-01-06
CA2513738C (en) 2010-04-06
BRPI0407097A (pt) 2006-01-24
TW200505823A (en) 2005-02-16
EP1619180A4 (de) 2006-05-24
ZA200505587B (en) 2006-09-27
US20050032796A1 (en) 2005-02-10
AU2004232604A8 (en) 2004-11-04
AU2004232604C1 (en) 2008-06-05
CA2513738A1 (en) 2004-11-04
US7304174B2 (en) 2007-12-04
JP3751312B2 (ja) 2006-03-01
CL2004000868A1 (es) 2005-01-21
KR100696927B1 (ko) 2007-03-20
PT1619180E (pt) 2009-12-29
KR20050094047A (ko) 2005-09-26
PL1619180T3 (pl) 2010-05-31
US20080255042A1 (en) 2008-10-16
EP2189439A2 (de) 2010-05-26
AU2004232604B8 (en) 2004-11-04
US20090326058A1 (en) 2009-12-31
EP1619180A1 (de) 2006-01-25
CO5640091A2 (es) 2006-05-31
MXPA05007609A (es) 2005-09-30
TWI329628B (en) 2010-09-01
CN101723921A (zh) 2010-06-09
AU2004232604B2 (en) 2007-09-13
AR044075A1 (es) 2005-08-24
NZ541188A (en) 2008-01-31
DE602004024668D1 (de) 2010-01-28
RU2005123985A (ru) 2006-01-27
WO2004094362A1 (ja) 2004-11-04
HK1083096A1 (en) 2006-06-23
EP2189439A3 (de) 2011-05-04
DK1619180T3 (da) 2010-03-29
HRP20100042T1 (hr) 2010-02-28
NO20054868L (no) 2005-12-20
US20120301552A1 (en) 2012-11-29
JPWO2004094362A1 (ja) 2006-07-13
IL169575A (en) 2011-07-31
RU2315036C2 (ru) 2008-01-20
SI1619180T1 (sl) 2010-04-30
EP2308828A3 (de) 2013-05-22
ES2337576T3 (es) 2010-04-27
IL169575A0 (en) 2007-07-04
AU2004232604A1 (en) 2004-11-04
EP2308828A2 (de) 2011-04-13
PE20050460A1 (es) 2005-07-08
CY1109880T1 (el) 2014-09-10
NO20054868D0 (no) 2005-10-21
EP1619180B1 (de) 2009-12-16
MY138734A (en) 2009-07-31

Similar Documents

Publication Publication Date Title
ATE452121T1 (de) Casr-antagonist
ATE363383T1 (de) Schlingenware
DE602004018130D1 (de) Kaffeeaufbrühvorrichtung
DE502004001683D1 (de) Kabelführung
DE602004031845D1 (de) Ng
AT502792A5 (de) Düsenanpressvorrichtung
DE502004000672D1 (de) Pigmentpreparationen
DE112004000620D2 (de) Struktoguss
DE10355350A8 (de) Elektromodul
DE502004001524D1 (de) Hydrolager
ATA662003A (de) Trink-mundstück
ATE446959T1 (de) Chromenonindole
DE502004002978D1 (de) N-biarylamide
DE602004018799D1 (de) Ng
DE502004001629D1 (de) Bremsenprüfstand
DK1633719T3 (da) Substituerede spirobenzazepiner
DE502004003122D1 (de) Hydrolager
DE502004000518D1 (de) Mitgängergabelhubwagen
DE10394329D2 (de) Mäanderstent
ATE406350T1 (de) Prolinylarylacetamide
DE10329218B4 (de) Hotflue
DE502004002771D1 (de) Umlenkhebel
DE502004004175D1 (de) Verbrennungskraftmaschime
DE502004002619D1 (de) Flaschenverschluss
EP1669443A4 (de) Pflanzenzwergwuchsgen

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1619180

Country of ref document: EP