ATE452343T1 - Verbesserte vitamin-d-messung - Google Patents

Verbesserte vitamin-d-messung

Info

Publication number
ATE452343T1
ATE452343T1 AT07725793T AT07725793T ATE452343T1 AT E452343 T1 ATE452343 T1 AT E452343T1 AT 07725793 T AT07725793 T AT 07725793T AT 07725793 T AT07725793 T AT 07725793T AT E452343 T1 ATE452343 T1 AT E452343T1
Authority
AT
Austria
Prior art keywords
vitamin
metabolite
measurement
sample
measuring
Prior art date
Application number
AT07725793T
Other languages
English (en)
Inventor
Uwe Kobold
Thomas Duelffer
Michael Grol
Rupert Herrmann
Der Eltz Herbert Von
Proff Leopold Von
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of ATE452343T1 publication Critical patent/ATE452343T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/20Oxygen containing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/20Oxygen containing
    • Y10T436/203332Hydroxyl containing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
AT07725793T 2006-06-06 2007-06-04 Verbesserte vitamin-d-messung ATE452343T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06011605 2006-06-06
PCT/EP2007/004924 WO2007140962A2 (en) 2006-06-06 2007-06-04 Improved measurement of vitamin d

Publications (1)

Publication Number Publication Date
ATE452343T1 true ATE452343T1 (de) 2010-01-15

Family

ID=36646176

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07725793T ATE452343T1 (de) 2006-06-06 2007-06-04 Verbesserte vitamin-d-messung

Country Status (9)

Country Link
US (1) US8003400B2 (de)
EP (1) EP2030026B1 (de)
JP (1) JP4953477B2 (de)
CN (1) CN101467048B (de)
AT (1) ATE452343T1 (de)
CA (1) CA2649338C (de)
DE (1) DE602007003833D1 (de)
ES (1) ES2336382T3 (de)
WO (1) WO2007140962A2 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7745226B2 (en) 2005-04-06 2010-06-29 Quest Diagnostics Investments Incorporated Methods for detecting vitamin D metabolites
US7972868B2 (en) 2007-11-28 2011-07-05 Quest Diagnostics Investments Incorporated Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry
US8409865B2 (en) * 2008-02-25 2013-04-02 Waters Technologies Corp. Methods and kits for the determination of the presence and quantity of vitamin D analogs in samples
EP2261655B1 (de) * 2008-03-31 2021-07-21 Sekisui Chemical Co., Ltd. Flüssigchromatographiekomponente mit filtern und einem vorfilter
US8399829B2 (en) 2008-12-18 2013-03-19 Quest Diagnostics Investments Incorporated Vitamin B2 detection by mass spectrometry
GB0903469D0 (en) * 2009-03-02 2009-04-08 Axis Shield Diagnostics Ltd Assay
US7977117B2 (en) 2009-12-03 2011-07-12 Quest Diagnostics Investments Incorprated Vitamin D metabolite determination utilizing mass spectrometry following derivatization
US9034653B2 (en) 2009-12-11 2015-05-19 Quest Diagnostics Investments Inc. Mass spectrometry of steroidal compounds in multiplexed patient samples
JP6113504B2 (ja) 2009-12-11 2017-04-12 クエスト ダイアグノスティックス インヴェストメンツ インコーポレイテッド 非誘導体化非代謝化ビタミンdの質量分析法による決定
JP5351076B2 (ja) * 2010-02-26 2013-11-27 杏林製薬株式会社 オンライン固相抽出による生体試料液中薬剤成分の定量方法
EP2372365A1 (de) * 2010-04-01 2011-10-05 Future Diagnostics B.V. Direkt-Immunoassay auf Vitamin D
EP2572204B1 (de) 2010-05-20 2017-12-27 Roche Diagnostics GmbH Freisetzungsreagens für vitamin d-verbindungen
CA2821415C (en) * 2010-12-28 2017-08-01 Future Diagnostics B.V. Release reagent for vitamin d
WO2014179737A2 (en) 2013-05-03 2014-11-06 The General Hospital Corporation Assays and methods of treatment relating to vitamin d insufficiency
US9052308B2 (en) 2011-01-07 2015-06-09 The General Hospital Corporation Assays and methods of treatment relating to vitamin D insufficiency
JP5918784B2 (ja) * 2011-01-07 2016-05-18 ザ ジェネラル ホスピタル コーポレイション ビタミンd欠乏症に関連するアッセイおよび治療方法
US8785603B2 (en) 2011-05-20 2014-07-22 Siemens Healthcare Diagnostics Inc. Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof
EP3467510B1 (de) * 2011-11-18 2022-10-26 F. Hoffmann-La Roche AG Freisetzungsreagens für vitamin-d-verbindungen
CN102692514A (zh) * 2012-06-21 2012-09-26 厦门大学 血液25-羟基维生素d3腺癌检测试剂盒及其制备方法
US9244083B2 (en) 2012-11-30 2016-01-26 Siemens Healthcare Diagnostics Inc. Compositions and methods for detecting vitamin D
JP6171333B2 (ja) * 2012-12-26 2017-08-02 東ソー株式会社 安定化したビタミンd類標準液
KR101840525B1 (ko) 2013-02-06 2018-03-20 후지레비오 가부시키가이샤 비타민 d 의 측정 방법 및 측정용 키트
US9618523B2 (en) 2013-02-28 2017-04-11 Siemens Healthcare Diagnostics Inc. Methods and reagents for determining isomeric analytes
US20140273021A1 (en) 2013-03-14 2014-09-18 Enzo Biochem, Inc. Vitamin d assays
DE102013205055A1 (de) * 2013-03-21 2014-09-25 Orgentec Diagnostika Gmbh Verfahren und Reagenz zur Bestimmung von Vitamin D Metaboliten
DE102013215580A1 (de) 2013-08-07 2015-02-12 Orgentec Diagnostika Gmbh 25-OH Vitamin D Derivate zur Bestimmung von Vitamin D Metaboliten
CN103467382A (zh) * 2013-09-16 2013-12-25 浙江丽晶化学有限公司 含硫氰酸根离子液体的制备方法及其在聚丙烯腈纺丝加工中的应用
US20150118689A1 (en) 2013-10-24 2015-04-30 Quidel Corporation Systems and methods for whole blood assays
CN104076155B (zh) * 2014-07-10 2016-08-31 深圳市新产业生物医学工程股份有限公司 用于检测25-羟基维生素d的检测剂及制备方法和应用
US10114030B2 (en) 2014-07-10 2018-10-30 Shenzhen New Industries Biomedical Engineering Co., Ltd Detection agent for detecting 25-hydroxy vitamin D, preparation method and use
CN105372337B (zh) * 2014-08-07 2017-11-10 山东达因海洋生物制药股份有限公司 一种检测维生素d滴剂中维生素d含量的方法
WO2017039574A1 (en) * 2015-08-28 2017-03-09 Enzo Life Sciences, Inc. Vitamin d assays
MX379918B (es) 2015-11-25 2025-03-11 Del Mar Pharmaceuticals Bc Ltd Metodos para analisis y resolucion de preparaciones de dianhidrogalactitol y derivados o analogos del mismo.
AU2016365824B2 (en) 2015-12-11 2022-07-21 Opko Diagnostics, Llc Fluidic systems involving incubation samples and/or reagents
CN106199015B (zh) * 2016-06-27 2018-08-17 江苏拜明生物技术有限公司 用于血清样品检测的维生素d释放剂、制备方法及应用
CN110068641A (zh) * 2018-01-22 2019-07-30 上海可力梅塔生物医药科技有限公司 25-羟基维生素d2和25-羟基维生素d3的hplc-ms/ms非衍生检测法
CN108982882A (zh) * 2018-06-22 2018-12-11 卢氏实验室公司 一种数字化信息化维生素d快速检测系统和方法
CN110794065A (zh) * 2018-08-03 2020-02-14 郑州泰丰制药有限公司 利用双三元检测骨化三醇软胶囊含量的方法
CN108663461B (zh) * 2018-08-06 2021-03-19 通标标准技术服务(上海)有限公司 一种测定奶粉中维生素d的方法
CN109358148A (zh) * 2018-09-20 2019-02-19 杭州和合医学检验实验室有限公司 血液中维生素d的检验方法
WO2022069392A1 (en) * 2020-09-29 2022-04-07 F. Hoffmann-La Roche Ag A method for determining the level of vitamin d and metabolites thereof
CN119322137A (zh) * 2024-12-17 2025-01-17 凯莱谱科技股份有限公司 血清维生素d代谢通路代谢物的液相色谱串联质谱检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5821020A (en) * 1995-07-14 1998-10-13 Nhh Biologics Vitamin D assay
CA2239617A1 (en) 1995-12-29 1997-07-10 A And D Assay, Incorporated Labeled vitamin d compounds and the use thereof
AU763458B2 (en) * 1998-06-25 2003-07-24 Biomedica Gmbh Functional vitamin D derivatives and a method for determining 25-hydroxy-vitamin D and 1alpha,25-dihydroxy-vitamin D
GB0029729D0 (en) * 2000-12-06 2001-01-17 Ids Ltd Method for detection of vitamin D metabolites
US7087395B1 (en) * 2001-01-16 2006-08-08 Quest Diagnostics Investments Incorporated Vitamin D assay
US20040132104A1 (en) 2003-01-07 2004-07-08 Sackrison James L. Vitamin D assay
CN101273272B (zh) * 2005-09-29 2012-11-07 霍夫曼-拉罗奇有限公司 维生素d化合物的释放试剂

Also Published As

Publication number Publication date
EP2030026B1 (de) 2009-12-16
WO2007140962A3 (en) 2008-01-31
JP4953477B2 (ja) 2012-06-13
CA2649338A1 (en) 2007-12-13
EP2030026A2 (de) 2009-03-04
CN101467048B (zh) 2014-04-02
CA2649338C (en) 2011-07-12
US8003400B2 (en) 2011-08-23
US20100285603A1 (en) 2010-11-11
CN101467048A (zh) 2009-06-24
JP2009540275A (ja) 2009-11-19
WO2007140962A2 (en) 2007-12-13
DE602007003833D1 (de) 2010-01-28
ES2336382T3 (es) 2010-04-12

Similar Documents

Publication Publication Date Title
DE602007003833D1 (de) Verbesserte vitamin-d-messung
WO2006126008A3 (en) Improved immunoassay methods
HK1199754A1 (en) Method for monitoring, diagnosis and/or prognosis of acute kidney injury in early stage
NZ609824A (en) Immunochromatography devices, methods and kits
WO2006026020A3 (en) Oncofetal fibronectin as a marker for disease and other conditions and methods for detection of oncofetal fibronectin
WO2008109075A3 (en) Biomarkers and methods for determining sensitivity to ctla-4 antagonists
EP2569635A4 (de) Verfahren zur diagnose und/oder behandlung von enzephalitis oder epilepsie
DE60129151D1 (de) Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6)
EP3907509A3 (de) Diagnose von bauchspeicheldrüsenkrebs im frühstadium
JP2012073260A5 (de)
EP3159695A3 (de) Verfahren zur diagnose von bauchspeicheldrüsenkrebs
ATE474228T1 (de) Reagenz für hämoglobinabbau
ATE519116T1 (de) Verfahren zur normierung der konzentration von analyten in einer urinprobe
WO2010054195A3 (en) Markers and methods for assessing and treating lupus patients susceptible to photoprovocation
WO2013166444A3 (en) Biomarker analysis using scodaphoresis
WO2007126901A3 (en) Apparatus and method for predicting disease
WO2011037827A3 (en) Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual
WO2009014987A3 (en) Identification and quantification of biomarkers for evaluating the risk of preterm birth
EP3736571A4 (de) Verfahren, reagenz und chip zur messung der analytkonzentration in einer biologischen probe
DE602006014798D1 (de) Vorrichtung und Verfahren zur Unterscheidung zwischen akuter und chronischer Myokardial-Nekrose bei symptomatischen Patienten
WO2007030949A3 (en) Methods of diagnosing ovarian cancer and kits therefor
PE20120592A1 (es) Metodo con biomarcadores para el seguimiento de un tratamiento
JP2022541169A5 (de)
WO2011149272A2 (ko) 단백질분해에 의하여 활성화되는 효소의 활성형의 정성적 및 정량적 분석방법
ATE495441T1 (de) Verfahren zum testen endokriner substanz in proben

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 2030026

Country of ref document: EP