ATE452343T1 - Verbesserte vitamin-d-messung - Google Patents

Verbesserte vitamin-d-messung

Info

Publication number: ATE452343T1
Authority: AT; Austria
Prior art keywords: vitamin; metabolite; measurement; sample; measuring
Prior art date: 2006-06-06

Application number

AT07725793T

Other languages

English (en)

Inventor

Uwe Kobold

Thomas Duelffer

Michael Grol

Rupert Herrmann

Der Eltz Herbert Von

Proff Leopold Von

Original Assignee

Hoffmann La Roche

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2006-06-06

Filing date

2007-06-04

Publication date

2010-01-15

2007-06-04 Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche

2010-01-15 Application granted granted Critical

2010-01-15 Publication of ATE452343T1 publication Critical patent/ATE452343T1/de

Links

238000005259 measurement Methods 0.000 title 1
229940088594 vitamin Drugs 0.000 title 1
229930003231 vitamin Natural products 0.000 title 1
235000013343 vitamin Nutrition 0.000 title 1
239000011782 vitamin Substances 0.000 title 1
150000003722 vitamin derivatives Chemical class 0.000 title 1
229930003316 Vitamin D Natural products 0.000 abstract 4
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 abstract 4
239000002207 metabolite Substances 0.000 abstract 4
238000000034 method Methods 0.000 abstract 4
235000019166 vitamin D Nutrition 0.000 abstract 4
239000011710 vitamin D Substances 0.000 abstract 4
150000003710 vitamin D derivatives Chemical class 0.000 abstract 4
229940046008 vitamin d Drugs 0.000 abstract 4
238000013375 chromatographic separation Methods 0.000 abstract 2
102000050760 Vitamin D-binding protein Human genes 0.000 abstract 1
101710179590 Vitamin D-binding protein Proteins 0.000 abstract 1
239000003153 chemical reaction reagent Substances 0.000 abstract 1
239000003795 chemical substances by application Substances 0.000 abstract 1
238000003745 diagnosis Methods 0.000 abstract 1
201000010099 disease Diseases 0.000 abstract 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
230000006920 protein precipitation Effects 0.000 abstract 1
235000020799 vitamin D status Nutrition 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/20—Oxygen containing
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/20—Oxygen containing
- Y10T436/203332—Hydroxyl containing

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Molecular Biology (AREA)
Biomedical Technology (AREA)
Chemical & Material Sciences (AREA)
Hematology (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Food Science & Technology (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
Biotechnology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Investigating Or Analysing Biological Materials (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

AT07725793T 2006-06-06 2007-06-04 Verbesserte vitamin-d-messung ATE452343T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP06011605		2006-06-06
PCT/EP2007/004924 WO2007140962A2 (en)	2006-06-06	2007-06-04	Improved measurement of vitamin d

Publications (1)

Publication Number	Publication Date
ATE452343T1 true ATE452343T1 (de)	2010-01-15

Family

ID=36646176

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT07725793T ATE452343T1 (de)	2006-06-06	2007-06-04	Verbesserte vitamin-d-messung

Country Status (9)

Country	Link
US (1)	US8003400B2 (de)
EP (1)	EP2030026B1 (de)
JP (1)	JP4953477B2 (de)
CN (1)	CN101467048B (de)
AT (1)	ATE452343T1 (de)
CA (1)	CA2649338C (de)
DE (1)	DE602007003833D1 (de)
ES (1)	ES2336382T3 (de)
WO (1)	WO2007140962A2 (de)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US7745226B2 (en)	2005-04-06	2010-06-29	Quest Diagnostics Investments Incorporated	Methods for detecting vitamin D metabolites
US7972868B2 (en)	2007-11-28	2011-07-05	Quest Diagnostics Investments Incorporated	Methods for detecting dihydroxyvitamin D metabolites by mass spectrometry
JP5449202B2 (ja) *	2008-02-25	2014-03-19	ウオーターズ・テクノロジーズ・コーポレイシヨン	サンプル中のビタミンｄ類似体の存在および量の決定のための方法およびキット
CN101978262B (zh) *	2008-03-31	2013-12-25	积水化学工业株式会社	液相色谱用构件
US8399829B2 (en)	2008-12-18	2013-03-19	Quest Diagnostics Investments Incorporated	Vitamin B2 detection by mass spectrometry
GB0903469D0 (en) *	2009-03-02	2009-04-08	Axis Shield Diagnostics Ltd	Assay
US7977117B2 (en)	2009-12-03	2011-07-12	Quest Diagnostics Investments Incorprated	Vitamin D metabolite determination utilizing mass spectrometry following derivatization
CA2783708C (en) *	2009-12-11	2018-09-18	Quest Diagnostics Investments Incorporated	Mass spectrometry of steroidal compounds in multiplex samples
US20110240840A1 (en)	2009-12-11	2011-10-06	Quest Diagnostics Investments Incorporated	Mass spectrometric determination of cookson-derivatized, non-metabolized vitamin d
JP5351076B2 (ja) *	2010-02-26	2013-11-27	杏林製薬株式会社	オンライン固相抽出による生体試料液中薬剤成分の定量方法
EP2372365A1 (de) *	2010-04-01	2011-10-05	Future Diagnostics B.V.	Direkt-Immunoassay auf Vitamin D
ES2795849T3 (es)	2010-05-20	2020-11-25	Hoffmann La Roche	Reactivo de liberación para compuestos de vitamina D
JP6138053B2 (ja) *	2010-12-28	2017-05-31	フューチャー・ダイアグノスティックス・ベーフェー	ビタミンｄのための放出試薬
JP5918784B2 (ja) *	2011-01-07	2016-05-18	ザジェネラルホスピタルコーポレイション	ビタミンｄ欠乏症に関連するアッセイおよび治療方法
US9052308B2 (en)	2011-01-07	2015-06-09	The General Hospital Corporation	Assays and methods of treatment relating to vitamin D insufficiency
WO2014179737A2 (en)	2013-05-03	2014-11-06	The General Hospital Corporation	Assays and methods of treatment relating to vitamin d insufficiency
US8785603B2 (en)	2011-05-20	2014-07-22	Siemens Healthcare Diagnostics Inc.	Antibodies to 25-hydroxyvitamin D2 and D3 and uses thereof
CA2852275C (en) *	2011-11-18	2021-06-29	F. Hoffmann-La Roche Ag	Release reagent for vitamin d compounds
CN102692514A (zh) *	2012-06-21	2012-09-26	厦门大学	血液25-羟基维生素d3腺癌检测试剂盒及其制备方法
US9244083B2 (en)	2012-11-30	2016-01-26	Siemens Healthcare Diagnostics Inc.	Compositions and methods for detecting vitamin D
JP6171333B2 (ja) *	2012-12-26	2017-08-02	東ソー株式会社	安定化したビタミンｄ類標準液
KR101840525B1 (ko) *	2013-02-06	2018-03-20	후지레비오 가부시키가이샤	비타민 d 의 측정 방법 및 측정용 키트
US9618523B2 (en)	2013-02-28	2017-04-11	Siemens Healthcare Diagnostics Inc.	Methods and reagents for determining isomeric analytes
US20140273021A1 (en)	2013-03-14	2014-09-18	Enzo Biochem, Inc.	Vitamin d assays
DE102013205055A1 (de) *	2013-03-21	2014-09-25	Orgentec Diagnostika Gmbh	Verfahren und Reagenz zur Bestimmung von Vitamin D Metaboliten
DE102013215580A1 (de)	2013-08-07	2015-02-12	Orgentec Diagnostika Gmbh	25-OH Vitamin D Derivate zur Bestimmung von Vitamin D Metaboliten
CN103467382A (zh) *	2013-09-16	2013-12-25	浙江丽晶化学有限公司	含硫氰酸根离子液体的制备方法及其在聚丙烯腈纺丝加工中的应用
US20150118689A1 (en)	2013-10-24	2015-04-30	Quidel Corporation	Systems and methods for whole blood assays
US10114030B2 (en)	2014-07-10	2018-10-30	Shenzhen New Industries Biomedical Engineering Co., Ltd	Detection agent for detecting 25-hydroxy vitamin D, preparation method and use
CN104076155B (zh) *	2014-07-10	2016-08-31	深圳市新产业生物医学工程股份有限公司	用于检测25-羟基维生素d的检测剂及制备方法和应用
CN105372337B (zh) *	2014-08-07	2017-11-10	山东达因海洋生物制药股份有限公司	一种检测维生素d滴剂中维生素d含量的方法
WO2017039574A1 (en) *	2015-08-28	2017-03-09	Enzo Life Sciences, Inc.	Vitamin d assays
CN108699018B (zh)	2015-11-25	2022-08-12	德玛医药（Bc）有限公司	双脱水半乳糖醇和其衍生物或类似物的制剂的分析和分辨方法
WO2017100457A1 (en) *	2015-12-11	2017-06-15	Opko Diagnostics, Llc	Fluidic systems involving incubation samples and/or reagents
CN106199015B (zh) *	2016-06-27	2018-08-17	江苏拜明生物技术有限公司	用于血清样品检测的维生素d释放剂、制备方法及应用
CN110068641A (zh) *	2018-01-22	2019-07-30	上海可力梅塔生物医药科技有限公司	25-羟基维生素d2和25-羟基维生素d3的hplc-ms/ms非衍生检测法
CN108982882A (zh) *	2018-06-22	2018-12-11	卢氏实验室公司	一种数字化信息化维生素d快速检测系统和方法
CN110794065A (zh) *	2018-08-03	2020-02-14	郑州泰丰制药有限公司	利用双三元检测骨化三醇软胶囊含量的方法
CN108663461B (zh) *	2018-08-06	2021-03-19	通标标准技术服务(上海)有限公司	一种测定奶粉中维生素d的方法
CN109358148A (zh) *	2018-09-20	2019-02-19	杭州和合医学检验实验室有限公司	血液中维生素d的检验方法
JP7805355B2 (ja) *	2020-09-29	2026-01-23	エフ．ホフマン－ラロシュアーゲー	ビタミンｄ及びその代謝産物のレベルを決定するための方法
CN119322137A (zh) *	2024-12-17	2025-01-17	凯莱谱科技股份有限公司	血清维生素d代谢通路代谢物的液相色谱串联质谱检测方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5821020A (en) *	1995-07-14	1998-10-13	Nhh Biologics	Vitamin D assay
US5981779A (en)	1995-12-29	1999-11-09	A And D Assay, Incorporated	Labeled vitamin D compounds and the use thereof
DE19981132D2 (de) *	1998-06-25	2001-10-18	Immundiagnostik Ges Fuer Produ	Funktionelle Vitamin-D-Derivate und Verfahren zur Bestimmung von 25-Hydroxy- und 1alpha,25-Dihydroxy-Vitamin-D
GB0029729D0 (en) *	2000-12-06	2001-01-17	Ids Ltd	Method for detection of vitamin D metabolites
US7087395B1 (en) *	2001-01-16	2006-08-08	Quest Diagnostics Investments Incorporated	Vitamin D assay
US20040132104A1 (en)	2003-01-07	2004-07-08	Sackrison James L.	Vitamin D assay
WO2007039194A1 (en) *	2005-09-29	2007-04-12	Roche Diagnostics Gmbh	Release reagent for vitamin d compounds

2007
- 2007-06-04 CA CA2649338A patent/CA2649338C/en active Active
- 2007-06-04 EP EP07725793A patent/EP2030026B1/de active Active
- 2007-06-04 JP JP2009513585A patent/JP4953477B2/ja active Active
- 2007-06-04 AT AT07725793T patent/ATE452343T1/de active
- 2007-06-04 WO PCT/EP2007/004924 patent/WO2007140962A2/en not_active Ceased
- 2007-06-04 ES ES07725793T patent/ES2336382T3/es active Active
- 2007-06-04 CN CN200780021252.0A patent/CN101467048B/zh active Active
- 2007-06-04 DE DE602007003833T patent/DE602007003833D1/de active Active
2008
- 2008-12-03 US US12/326,972 patent/US8003400B2/en active Active

Also Published As

Publication number	Publication date
DE602007003833D1 (de)	2010-01-28
JP2009540275A (ja)	2009-11-19
EP2030026B1 (de)	2009-12-16
EP2030026A2 (de)	2009-03-04
US8003400B2 (en)	2011-08-23
WO2007140962A3 (en)	2008-01-31
CA2649338A1 (en)	2007-12-13
ES2336382T3 (es)	2010-04-12
CA2649338C (en)	2011-07-12
US20100285603A1 (en)	2010-11-11
JP4953477B2 (ja)	2012-06-13
CN101467048A (zh)	2009-06-24
CN101467048B (zh)	2014-04-02
WO2007140962A2 (en)	2007-12-13

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2010-07-15

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