ATE452906T1 - THERAPEUTIC SUMMARY AND METHODS FOR MODULATING V3, AN ISOFORM OF VERSICAN - Google Patents

THERAPEUTIC SUMMARY AND METHODS FOR MODULATING V3, AN ISOFORM OF VERSICAN

Info

Publication number
ATE452906T1
ATE452906T1 AT01926904T AT01926904T ATE452906T1 AT E452906 T1 ATE452906 T1 AT E452906T1 AT 01926904 T AT01926904 T AT 01926904T AT 01926904 T AT01926904 T AT 01926904T AT E452906 T1 ATE452906 T1 AT E452906T1
Authority
AT
Austria
Prior art keywords
versican
isoform
modulating
therapeutic
methods
Prior art date
Application number
AT01926904T
Other languages
German (de)
Inventor
Thomas N Wight
Mervyn Merrilees
Original Assignee
Thomas N Wight
Mervyn Merrilees
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomas N Wight, Mervyn Merrilees filed Critical Thomas N Wight
Application granted granted Critical
Publication of ATE452906T1 publication Critical patent/ATE452906T1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4725—Proteoglycans, e.g. aggreccan
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

A method of increasing elastic fibers in human tissue comprises contacting the tissue ex vivo with an effective amount of an agent, wherein the agent increases the amount or activity of versican v3 in said tissue.
AT01926904T 2000-04-13 2001-04-12 THERAPEUTIC SUMMARY AND METHODS FOR MODULATING V3, AN ISOFORM OF VERSICAN ATE452906T1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19680500P 2000-04-13 2000-04-13
PCT/US2001/011940 WO2001079284A2 (en) 2000-04-13 2001-04-12 Therapeutic compounds and methods for formulating v3, a versican isoform

Publications (1)

Publication Number Publication Date
ATE452906T1 true ATE452906T1 (en) 2010-01-15

Family

ID=22726861

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01926904T ATE452906T1 (en) 2000-04-13 2001-04-12 THERAPEUTIC SUMMARY AND METHODS FOR MODULATING V3, AN ISOFORM OF VERSICAN

Country Status (8)

Country Link
US (2) US7816335B2 (en)
EP (2) EP1274726B1 (en)
JP (1) JP2003530841A (en)
AT (1) ATE452906T1 (en)
AU (2) AU2001253408C1 (en)
CA (1) CA2406192A1 (en)
DE (1) DE60140864D1 (en)
WO (1) WO2001079284A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001253408C1 (en) * 2000-04-13 2008-12-04 Mervyn Merrilees Therapeutic compounds and methods for formulating V3, A Versican Isoform
EP2114435A1 (en) * 2007-02-02 2009-11-11 Novartis AG Modulators of sclerostin binding partners for treating bone-related disorders
WO2008100789A2 (en) * 2007-02-16 2008-08-21 Benaroya Research Institute At Virginia Mason Compositions and methods for altering elastogenesis
WO2009061368A1 (en) * 2007-11-06 2009-05-14 Benaroya Research Institute Inhibition of versican with sirna and other molecules
US7811776B2 (en) * 2007-12-05 2010-10-12 University Of Cincinnati Use of VEGF-D in the diagnosis of lymphangioleiomyomatosis (LAM) disease
WO2013025936A1 (en) 2011-08-18 2013-02-21 Cornell University Detection and treatment of metastatic disease
US10940199B2 (en) * 2016-03-09 2021-03-09 Wisconsin Alumni Research Foundation Versikine for inducing and potentiating an immune response
WO2020038971A1 (en) * 2018-08-23 2020-02-27 Roche Innovation Center Copenhagen A/S Antisense oligonucleotides targeting vcan
US11840703B2 (en) 2019-07-01 2023-12-12 Matrexa LLC Recombinant versican isoforms and related compositions and methods
WO2025038850A1 (en) * 2023-08-15 2025-02-20 The Regents Of The University Of California Lipid nanoparticles and methods for sensitizing response to an immunotherapy

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Also Published As

Publication number Publication date
AU2001253408C1 (en) 2008-12-04
EP1274726B1 (en) 2009-12-23
CA2406192A1 (en) 2001-10-25
WO2001079284A3 (en) 2002-08-29
US20110124567A1 (en) 2011-05-26
AU2001253408B2 (en) 2007-04-05
EP2202241A3 (en) 2010-07-28
JP2003530841A (en) 2003-10-21
AU5340801A (en) 2001-10-30
EP2202241A2 (en) 2010-06-30
US7816335B2 (en) 2010-10-19
US20040213762A1 (en) 2004-10-28
DE60140864D1 (en) 2010-02-04
WO2001079284A2 (en) 2001-10-25
EP1274726A2 (en) 2003-01-15

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