ATE453410T1 - Stabile zubereitungen mit hyperforin - Google Patents
Stabile zubereitungen mit hyperforinInfo
- Publication number
- ATE453410T1 ATE453410T1 AT99960848T AT99960848T ATE453410T1 AT E453410 T1 ATE453410 T1 AT E453410T1 AT 99960848 T AT99960848 T AT 99960848T AT 99960848 T AT99960848 T AT 99960848T AT E453410 T1 ATE453410 T1 AT E453410T1
- Authority
- AT
- Austria
- Prior art keywords
- hyperforin
- stable preparations
- stabilized
- complexing agents
- preparations
- Prior art date
Links
- QOVWXXKVLJOKNW-UHFFFAOYSA-N hyperforin Natural products CC(C)C(=O)C12CC(CC=C(C)C)(CC(CC=C(C)C)C1CCC=C(C)C)C(=C(CC=C(C)C)C2=O)O QOVWXXKVLJOKNW-UHFFFAOYSA-N 0.000 title abstract 3
- KGSZHKRKHXOAMG-HQKKAZOISA-N (1r,5r,6r,7s)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione Chemical compound O=C1C(CC=C(C)C)=C(O)[C@@]2(CC=C(C)C)C[C@H](CC=C(C)C)[C@](CCC=C(C)C)(C)[C@]1(C(=O)C(C)C)C2=O KGSZHKRKHXOAMG-HQKKAZOISA-N 0.000 title 1
- 238000002360 preparation method Methods 0.000 title 1
- 239000008139 complexing agent Substances 0.000 abstract 2
- IWBJJCOKGLUQIZ-HQKKAZOISA-N hyperforin Chemical compound OC1=C(CC=C(C)C)C(=O)[C@@]2(CC=C(C)C)C[C@H](CC=C(C)C)[C@](CCC=C(C)C)(C)[C@]1(C(=O)C(C)C)C2=O IWBJJCOKGLUQIZ-HQKKAZOISA-N 0.000 abstract 2
- 239000012141 concentrate Substances 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000000284 extract Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/78—Separation; Purification; Stabilisation; Use of additives
- C07C45/86—Use of additives, e.g. for stabilisation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Epidemiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19850844 | 1998-11-04 | ||
| DE19903570A DE19903570A1 (de) | 1998-11-04 | 1999-01-29 | Stabile Zubereitungen mit Hyperforin |
| PCT/DE1999/003485 WO2000025824A2 (de) | 1998-11-04 | 1999-11-02 | Stabile zubereitungen mit hyperforin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE453410T1 true ATE453410T1 (de) | 2010-01-15 |
Family
ID=7886675
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99960848T ATE453410T1 (de) | 1998-11-04 | 1999-11-02 | Stabile zubereitungen mit hyperforin |
Country Status (2)
| Country | Link |
|---|---|
| AT (1) | ATE453410T1 (de) |
| DE (2) | DE19903570A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000054785A2 (en) * | 1999-03-15 | 2000-09-21 | Shaman Pharmaceuticals, Inc. | Stabilized bicyclo[3.3.1]nonenes and methods of use |
| DE10131641A1 (de) | 2000-12-22 | 2002-06-27 | Schwabe Willmar Gmbh & Co | Verbesserter und stabiler Extrakt aus Hypericum perforatum L., Verfahren zu seiner Herstellung und Verwendung als topisches Arzneimittel |
-
1999
- 1999-01-29 DE DE19903570A patent/DE19903570A1/de not_active Withdrawn
- 1999-11-02 DE DE59915118T patent/DE59915118D1/de not_active Expired - Lifetime
- 1999-11-02 AT AT99960848T patent/ATE453410T1/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DE59915118D1 (de) | 2010-02-11 |
| DE19903570A1 (de) | 2000-05-11 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| REN | Ceased due to non-payment of the annual fee |