ATE454381T1 - Benzofuranderivat - Google Patents

Benzofuranderivat

Info

Publication number
ATE454381T1
ATE454381T1 AT03712982T AT03712982T ATE454381T1 AT E454381 T1 ATE454381 T1 AT E454381T1 AT 03712982 T AT03712982 T AT 03712982T AT 03712982 T AT03712982 T AT 03712982T AT E454381 T1 ATE454381 T1 AT E454381T1
Authority
AT
Austria
Prior art keywords
benzofuran derivative
benzofuran
derivative
Prior art date
Application number
AT03712982T
Other languages
English (en)
Inventor
Takayuki Kawaguchi
Hidenori Akatsuka
Toru Iijima
Yasunori Tsuboi
Takashi Mitsui
Jun Murakami
Original Assignee
Mitsubishi Tanabe Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Tanabe Pharma Corp filed Critical Mitsubishi Tanabe Pharma Corp
Application granted granted Critical
Publication of ATE454381T1 publication Critical patent/ATE454381T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT03712982T 2002-03-28 2003-03-27 Benzofuranderivat ATE454381T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2002091686 2002-03-28
JP2002376158 2002-12-26
PCT/JP2003/003807 WO2003082847A1 (en) 2002-03-28 2003-03-27 Benzofuran derivative

Publications (1)

Publication Number Publication Date
ATE454381T1 true ATE454381T1 (de) 2010-01-15

Family

ID=28677558

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03712982T ATE454381T1 (de) 2002-03-28 2003-03-27 Benzofuranderivat

Country Status (22)

Country Link
US (2) US7531537B2 (de)
EP (1) EP1489078B1 (de)
KR (1) KR100702889B1 (de)
CN (1) CN100439351C (de)
AR (1) AR039190A1 (de)
AT (1) ATE454381T1 (de)
AU (1) AU2003221178B2 (de)
BR (1) BR0308796A (de)
CA (1) CA2479831C (de)
DE (1) DE60330847D1 (de)
DK (1) DK1489078T3 (de)
ES (1) ES2336905T3 (de)
IL (1) IL163923A0 (de)
MX (1) MXPA04009477A (de)
MY (1) MY144928A (de)
NO (1) NO331281B1 (de)
NZ (1) NZ535267A (de)
PL (1) PL372548A1 (de)
PT (1) PT1489078E (de)
RU (1) RU2286344C2 (de)
TW (1) TWI277416B (de)
WO (1) WO2003082847A1 (de)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070004736A1 (en) * 2002-11-22 2007-01-04 Keiji Kubo Imidazole derivative, process for producing the same, and use
JP2005104838A (ja) 2003-01-09 2005-04-21 Tanabe Seiyaku Co Ltd 縮合フラン化合物
TWI312345B (en) 2003-06-30 2009-07-21 Mitsubishi Tanabe Pharma Corp Process of preparating 3-acylaminobenzofuran-2-carboxylic acid derivatives
US7265148B2 (en) * 2003-09-25 2007-09-04 Wyeth Substituted pyrrole-indoles
TW200524915A (en) 2003-09-26 2005-08-01 Tanabe Seiyaku Co Carbamoyl-type benzofuran derivatives
TW200512181A (en) * 2003-09-26 2005-04-01 Tanabe Seiyaku Co Amide-type carboxamide derivatives
FR2862965B1 (fr) * 2003-11-27 2007-09-07 Merck Sante Sas Nouveaux derives de phenoxyacetamides et leur utilisation pour la preparation de diphenylamides.
DE102004023507A1 (de) * 2004-05-10 2005-12-01 Grünenthal GmbH Substituierte Cyclohexylessigsäure-Derivate
TWI396686B (zh) 2004-05-21 2013-05-21 Takeda Pharmaceutical 環狀醯胺衍生物、以及其製品和用法
JP4710445B2 (ja) * 2004-07-08 2011-06-29 田辺三菱製薬株式会社 医薬組成物
JP2006298909A (ja) * 2005-03-25 2006-11-02 Tanabe Seiyaku Co Ltd 医薬組成物
US8273900B2 (en) 2008-08-07 2012-09-25 Novartis Ag Organic compounds
JP5685181B2 (ja) 2009-03-05 2015-03-18 塩野義製薬株式会社 Npyy5受容体拮抗作用を有するシクロヘキサン誘導体
UY34295A (es) * 2011-09-08 2013-04-30 Servier Lab Nuevo esquema de administración de la n-hidroxi -4- {2-[3- (n,ndimetilaminometil)benzofuran -2- ilcarbonilamino]etoxi}benzamida
EP2780015B1 (de) 2011-11-18 2017-01-04 Heptares Therapeutics Limited M1 muskarinrezeptoragonisten
GB201404922D0 (en) 2014-03-19 2014-04-30 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201513743D0 (en) 2015-08-03 2015-09-16 Heptares Therapeutics Ltd Muscarinic agonists
GB201519352D0 (en) 2015-11-02 2015-12-16 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201617454D0 (en) 2016-10-14 2016-11-30 Heptares Therapeutics Limited Pharmaceutical compounds
MY202326A (en) 2017-09-14 2024-04-24 Daiichi Sankyo Co Ltd Compound having cyclic structure
GB201810239D0 (en) 2018-06-22 2018-08-08 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819960D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB201819961D0 (en) 2018-12-07 2019-01-23 Heptares Therapeutics Ltd Pharmaceutical compounds
GB202020191D0 (en) 2020-12-18 2021-02-03 Heptares Therapeutics Ltd Pharmaceutical compounds

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9005014D0 (en) * 1990-03-06 1990-05-02 Janssen Pharmaceutica Nv N.(4.piperidinyl)(dihydrobenzofuran or dihydro.2h.benzopyran)carboxamide derivatives
IT1239946B (it) * 1990-03-12 1993-11-27 Biomedica Foscama Industria Chimicofarmaceutica Procedimento per la sintesi degli acidi 5-acilossi e 5-alcossi-2,3-diidro-4,6,7-trimetil-2-(rs)-benzofuranacetici
US5814636A (en) * 1994-07-15 1998-09-29 Meiji Seika Kabushiki Kaisha Compounds with platelet aggregation inhibitor activity
ATE239004T1 (de) * 1996-05-20 2003-05-15 Darwin Discovery Ltd Benzofuran carboxamide und ihre therapeutische anwendung
EP0937711A1 (de) 1998-02-18 1999-08-25 Roche Diagnostics GmbH Neue Thiobenzamide, Verfahren zu ihrer Herstellung sowie diese enthaltende Arzneimittel
AU2055500A (en) 1998-12-23 2000-07-31 Eli Lilly And Company Aromatic amides
EP1310488A4 (de) 2000-08-09 2005-08-10 Mitsubishi Pharma Corp Kondensierte bizyklische amidverbindungen und ihre medizinische verwendung
TW200524915A (en) * 2003-09-26 2005-08-01 Tanabe Seiyaku Co Carbamoyl-type benzofuran derivatives

Also Published As

Publication number Publication date
US7531537B2 (en) 2009-05-12
AR039190A1 (es) 2005-02-09
DE60330847D1 (de) 2010-02-25
RU2004131680A (ru) 2005-06-27
RU2286344C2 (ru) 2006-10-27
ES2336905T3 (es) 2010-04-19
MY144928A (en) 2011-11-30
CN1656086A (zh) 2005-08-17
US20050282808A1 (en) 2005-12-22
EP1489078A4 (de) 2006-01-04
CN100439351C (zh) 2008-12-03
DK1489078T3 (da) 2010-03-15
KR100702889B1 (ko) 2007-04-04
IL163923A0 (en) 2005-12-18
NO20044644L (no) 2004-12-16
TW200306812A (en) 2003-12-01
CA2479831A1 (en) 2003-10-09
CA2479831C (en) 2010-06-08
BR0308796A (pt) 2005-01-11
NO331281B1 (no) 2011-11-14
PL372548A1 (en) 2005-07-25
HK1069396A1 (en) 2005-05-20
EP1489078A1 (de) 2004-12-22
WO2003082847A1 (en) 2003-10-09
US20090209511A1 (en) 2009-08-20
KR20040111442A (ko) 2004-12-31
EP1489078B1 (de) 2010-01-06
MXPA04009477A (es) 2005-01-25
TWI277416B (en) 2007-04-01
NZ535267A (en) 2006-03-31
PT1489078E (pt) 2010-02-24
AU2003221178A1 (en) 2003-10-13
AU2003221178B2 (en) 2006-06-15

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