ATE455850T1 - Contortrostatin(cn) sowie verfahren zu seiner verwendung in der prävention von metastasen und anderer zustände - Google Patents

Contortrostatin(cn) sowie verfahren zu seiner verwendung in der prävention von metastasen und anderer zustände

Info

Publication number
ATE455850T1
ATE455850T1 AT99956502T AT99956502T ATE455850T1 AT E455850 T1 ATE455850 T1 AT E455850T1 AT 99956502 T AT99956502 T AT 99956502T AT 99956502 T AT99956502 T AT 99956502T AT E455850 T1 ATE455850 T1 AT E455850T1
Authority
AT
Austria
Prior art keywords
contortrostatin
proteins
amino acid
protein
precursor
Prior art date
Application number
AT99956502T
Other languages
English (en)
Inventor
Francis Markland
Qing Zhou
Original Assignee
Univ Southern California
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Southern California filed Critical Univ Southern California
Application granted granted Critical
Publication of ATE455850T1 publication Critical patent/ATE455850T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Biophysics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Amplifiers (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AT99956502T 1998-09-29 1999-09-29 Contortrostatin(cn) sowie verfahren zu seiner verwendung in der prävention von metastasen und anderer zustände ATE455850T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16304798A 1998-09-29 1998-09-29
PCT/US1999/022608 WO2000018421A1 (en) 1998-09-29 1999-09-29 Contortrostatin (cn) and methods for its use in preventing metastasis and other conditions

Publications (1)

Publication Number Publication Date
ATE455850T1 true ATE455850T1 (de) 2010-02-15

Family

ID=22588249

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99956502T ATE455850T1 (de) 1998-09-29 1999-09-29 Contortrostatin(cn) sowie verfahren zu seiner verwendung in der prävention von metastasen und anderer zustände

Country Status (9)

Country Link
EP (1) EP1117419B1 (de)
JP (1) JP2002528058A (de)
AT (1) ATE455850T1 (de)
AU (1) AU1309900A (de)
BR (1) BR9914466A (de)
CA (1) CA2343716C (de)
DE (1) DE69941956D1 (de)
ES (1) ES2339620T3 (de)
WO (1) WO2000018421A1 (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7220724B2 (en) 1993-10-22 2007-05-22 University Of Southern California Contortrostatin CN and methods for its use in preventing metastasis and other conditions
AU2077001A (en) * 1999-12-10 2001-06-18 University Of Southern California Contortrostatin (cn) and methods for its use in preventing metastasis and other conditions
US7754850B2 (en) 2005-02-11 2010-07-13 University Of Southern California Chimeric disintegrin domain
CN101143894A (zh) * 2007-06-22 2008-03-19 中国药科大学 高效抑制血管生成多肽及其物理化学修饰方法和应用
CN101113448B (zh) * 2007-07-03 2010-05-19 赵宝昌 白眉蝮蛇去整合素定点突变体cDNA的克隆、表达及其蛋白质制法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA889415B (en) * 1987-12-18 1989-09-27 Chiron Corp Compositions and method for recombinant production of crotalidus venum fibrolase
US5182260A (en) * 1989-01-27 1993-01-26 Biogen, Inc. Dna sequences encoding snake venom inhibitors of platelet activation processes for producing those inhibitors and compositions using them
US5731288A (en) * 1993-10-22 1998-03-24 University Of Southern California Compositions containing contortrostatin and methods for the use thereof
KR0142606B1 (ko) * 1995-07-05 1998-07-01 허영섭 혈소판 응집 억제 펩타이드 및 그의 제조방법

Also Published As

Publication number Publication date
CA2343716C (en) 2013-01-22
EP1117419A4 (de) 2003-05-14
EP1117419B1 (de) 2010-01-20
CA2343716A1 (en) 2000-04-06
BR9914466A (pt) 2001-10-16
AU1309900A (en) 2000-04-17
JP2002528058A (ja) 2002-09-03
WO2000018421A1 (en) 2000-04-06
EP1117419A1 (de) 2001-07-25
ES2339620T3 (es) 2010-05-21
DE69941956D1 (de) 2010-03-11
WO2000018421A9 (en) 2001-03-22

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Legal Events

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