ATE456960T1 - Neue integrin-bindende rgd-lipopeptide mit gentransferaktivitäten - Google Patents

Neue integrin-bindende rgd-lipopeptide mit gentransferaktivitäten

Info

Publication number
ATE456960T1
ATE456960T1 AT07734148T AT07734148T ATE456960T1 AT E456960 T1 ATE456960 T1 AT E456960T1 AT 07734148 T AT07734148 T AT 07734148T AT 07734148 T AT07734148 T AT 07734148T AT E456960 T1 ATE456960 T1 AT E456960T1
Authority
AT
Austria
Prior art keywords
lipopeptides
integrin
gene transfer
binding rgd
binding
Prior art date
Application number
AT07734148T
Other languages
English (en)
Inventor
Bharat Majeti
Priya Karmali
Pramanik Dipankar
Arabinda Chaudhuri
Original Assignee
Council Scient Ind Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Council Scient Ind Res filed Critical Council Scient Ind Res
Application granted granted Critical
Publication of ATE456960T1 publication Critical patent/ATE456960T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Enzymes And Modification Thereof (AREA)
AT07734148T 2006-03-31 2007-03-30 Neue integrin-bindende rgd-lipopeptide mit gentransferaktivitäten ATE456960T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN924DE2006 2006-03-31
PCT/IB2007/000826 WO2007116276A2 (en) 2006-03-31 2007-03-30 Integrin binding rgd-lipopeptides with gene transfer activities

Publications (1)

Publication Number Publication Date
ATE456960T1 true ATE456960T1 (de) 2010-02-15

Family

ID=38456507

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07734148T ATE456960T1 (de) 2006-03-31 2007-03-30 Neue integrin-bindende rgd-lipopeptide mit gentransferaktivitäten

Country Status (6)

Country Link
US (1) US9403869B2 (de)
EP (1) EP2004239B1 (de)
JP (1) JP5078987B2 (de)
AT (1) ATE456960T1 (de)
DE (1) DE602007004668D1 (de)
WO (1) WO2007116276A2 (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5317105B2 (ja) * 2009-01-13 2013-10-16 国立大学法人 筑波大学 四級化アミノ基を有する架橋ポリマー由来のポリマー微粒子と核酸の複合体
US8263133B2 (en) * 2009-02-18 2012-09-11 The Regents Of The University Of California Multivalent clustering targeting strategy for drug carriers
CA2805403A1 (en) * 2009-07-10 2011-01-13 Trustees Of Tufts College Bioengineered silk protein-based nucleic acid delivery systems
WO2017062502A1 (en) * 2015-10-05 2017-04-13 The Regents Of The University Of Colorgo, A Body Corporate Lipoplexes formulated for catalytic delivery

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69118826T2 (de) 1990-11-27 1996-11-14 Fuji Photo Film Co Ltd Propenamidderivate, deren Polymere, Copolymere und deren Verwendung
AU3876695A (en) * 1994-11-17 1996-06-17 Imperial College Of Science, Technology And Medicine Internalisation of dna, using conjugates of poly-l-lysine and an integrin receptor ligand
US6333433B1 (en) * 1998-11-09 2001-12-25 Council Of Scientific Industrial Research Process for synthesis of novel cationic amphiphiles containing N-hydroxyalkl group for intracellular delivery of biologically active molecules

Also Published As

Publication number Publication date
WO2007116276A2 (en) 2007-10-18
EP2004239B1 (de) 2010-02-03
EP2004239A2 (de) 2008-12-24
WO2007116276A3 (en) 2007-12-21
JP5078987B2 (ja) 2012-11-21
DE602007004668D1 (de) 2010-03-25
US20100234289A1 (en) 2010-09-16
JP2009531409A (ja) 2009-09-03
US9403869B2 (en) 2016-08-02

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Legal Events

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