ATE458487T1 - Tumorbehandlung mit gliotoxin-derivaten - Google Patents

Tumorbehandlung mit gliotoxin-derivaten

Info

Publication number
ATE458487T1
ATE458487T1 AT06760774T AT06760774T ATE458487T1 AT E458487 T1 ATE458487 T1 AT E458487T1 AT 06760774 T AT06760774 T AT 06760774T AT 06760774 T AT06760774 T AT 06760774T AT E458487 T1 ATE458487 T1 AT E458487T1
Authority
AT
Austria
Prior art keywords
tumor treatment
gliotoxin
derivatives
gliotoxin derivatives
tumours
Prior art date
Application number
AT06760774T
Other languages
English (en)
Inventor
Rainer Hubmann
Wolfgang Sieghart
Original Assignee
Univ Wien Med
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Wien Med filed Critical Univ Wien Med
Application granted granted Critical
Publication of ATE458487T1 publication Critical patent/ATE458487T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/548—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame having two or more sulfur atoms in the same ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
AT06760774T 2005-06-21 2006-06-21 Tumorbehandlung mit gliotoxin-derivaten ATE458487T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0104405A AT502055B1 (de) 2005-06-21 2005-06-21 Anti tumor medikament
PCT/AT2006/000253 WO2006135949A2 (en) 2005-06-21 2006-06-21 Tumour treatment with gliotoxin derivatives

Publications (1)

Publication Number Publication Date
ATE458487T1 true ATE458487T1 (de) 2010-03-15

Family

ID=37102560

Family Applications (2)

Application Number Title Priority Date Filing Date
AT0104405A AT502055B1 (de) 2005-06-21 2005-06-21 Anti tumor medikament
AT06760774T ATE458487T1 (de) 2005-06-21 2006-06-21 Tumorbehandlung mit gliotoxin-derivaten

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT0104405A AT502055B1 (de) 2005-06-21 2005-06-21 Anti tumor medikament

Country Status (7)

Country Link
US (1) US7981878B2 (de)
EP (1) EP1901750B1 (de)
AT (2) AT502055B1 (de)
AU (1) AU2006261566A1 (de)
CA (1) CA2612770A1 (de)
DE (1) DE602006012487D1 (de)
WO (1) WO2006135949A2 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012161799A1 (en) * 2011-02-24 2012-11-29 Georgia Health Sciences University Research Institute, Inc Epidithiodioxopiperazines and uses thereof in treating cancer
US9442092B2 (en) 2011-06-20 2016-09-13 Kerry Lane Methods for treatment of autism
CA2849011A1 (en) * 2011-10-05 2013-04-11 Genentech, Inc. Methods of treating liver conditions using notch2 antagonists
US9765090B2 (en) 2011-11-25 2017-09-19 Ewha University-Industry Collaboration Foundation Epidithiodioxopiperazine compound or its derivatives, and the use thereof
KR20200143502A (ko) 2012-08-13 2020-12-23 제넨테크, 인크. 항-jagged 항체 및 사용 방법
US9944700B2 (en) 2013-03-13 2018-04-17 Novartis Ag Notch2 binding molecules for treating respiratory diseases
AU2014236815B2 (en) 2013-03-15 2019-04-04 Genentech, Inc. Compositions and methods for diagnosis and treatment of hepatic cancers
EP2958926B1 (de) * 2013-05-24 2023-03-08 VASTHERA Co. Ltd. Epidithiodioxopiperazinverbindung oder derivate davon und verwendung davon
EP3105253B1 (de) 2014-02-12 2018-06-27 F. Hoffmann-La Roche AG Anti-jagged1-antikörper und verfahren zur verwendung
EP3282019A1 (de) 2016-08-09 2018-02-14 Medizinische Universität Wien Genotypisierung und behandlung von krebs, insbesondere chronischer lymphozytischer leukämie
KR102091730B1 (ko) * 2017-07-05 2020-03-23 바스테라 주식회사 에피디티오디옥소피페라진 화합물 또는 이의 유도체, 또는 이들의 약학적으로 허용가능한 염을 포함하는 폐동맥고혈압 예방 또는 치료용 약학적 조성물
CN114641294B (zh) * 2019-08-28 2024-09-13 瓦西特拉有限公司 用于预防或治疗实体癌的包含桥二硫二氧代哌嗪衍生物或其药学上可接受的盐的药物组合物
CN116286897B (zh) * 2023-03-29 2024-05-03 佛山科学技术学院 一种编码酰基转移酶的Tri3基因及其应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4727018A (en) 1984-05-18 1988-02-23 Eichner Ronald D Immunoregulation of transplantable tissue
JPS61277617A (ja) 1985-05-31 1986-12-08 Yakult Honsha Co Ltd 坑血小板凝集剤
WO1992010198A1 (en) * 1990-12-06 1992-06-25 Johnson & Johnson Research Pty Limited Immunotherapeutic agents, compositions and methods
JP2801491B2 (ja) 1993-01-26 1998-09-21 敦 沼田 エピポリチオジオキソピペラジン誘導体およびその製造法
JP3498925B2 (ja) 1994-02-18 2004-02-23 日本肥糧株式会社 グリオクラディウム・ビレンスによるグリオトキシンの生産方法
KR19990082168A (ko) * 1996-12-02 1999-11-25 에가시라 구니오 글리오톡신 유도체 및 이를 함유하는 항암제
US6703221B1 (en) * 1999-08-19 2004-03-09 Chiron Corporation Notch receptor ligands and uses thereof
US20040101847A1 (en) * 2002-11-22 2004-05-27 Isis Pharmaceuticals Inc. Modulation of Notch2 expression
US20040001847A1 (en) 2002-06-26 2004-01-01 Lasalvia-Prisco Eduardo M. Method and composition to elicit an effective autologous antitumoral immune response in a patient
JP2006510586A (ja) 2002-08-29 2006-03-30 ユニバーシティー オブ サザンプトン 肝疾患治療のための薬剤の調製におけるアポトーシス誘導物質の使用方法

Also Published As

Publication number Publication date
WO2006135949A2 (en) 2006-12-28
AT502055B1 (de) 2007-11-15
CA2612770A1 (en) 2006-12-28
US7981878B2 (en) 2011-07-19
US20090029974A1 (en) 2009-01-29
DE602006012487D1 (de) 2010-04-08
EP1901750B1 (de) 2010-02-24
AU2006261566A1 (en) 2006-12-28
AT502055A1 (de) 2007-01-15
WO2006135949A3 (en) 2007-07-05
EP1901750A2 (de) 2008-03-26

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