ATE458752T1 - Natrium abhängiger gallensäure transporter und dessen verwendung - Google Patents

Natrium abhängiger gallensäure transporter und dessen verwendung

Info

Publication number: ATE458752T1
Authority: AT; Austria
Prior art keywords: diseases; acid transporter; digestive; bale; protein
Prior art date: 2002-01-18

Application number

AT03701099T

Other languages

English (en)

Inventor

Yumiko Uno

Yukiko Hikichi

Yoji Sagiya

Atsushi Nakanishi

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-01-18

Filing date

2003-01-16

Publication date

2010-03-15

2003-01-16 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2010-03-15 Application granted granted Critical

2010-03-15 Publication of ATE458752T1 publication Critical patent/ATE458752T1/de

Links

239000011734 sodium Substances 0.000 title abstract 3
DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 title abstract 2
230000001419 dependent effect Effects 0.000 title abstract 2
229910052708 sodium Inorganic materials 0.000 title abstract 2
239000002253 acid Substances 0.000 title 1
208000010643 digestive system disease Diseases 0.000 abstract 3
201000010099 disease Diseases 0.000 abstract 2
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
208000023504 respiratory system disease Diseases 0.000 abstract 2
206010003210 Arteriosclerosis Diseases 0.000 abstract 1
108010078791 Carrier Proteins Proteins 0.000 abstract 1
208000022555 Genital disease Diseases 0.000 abstract 1
206010029333 Neurosis Diseases 0.000 abstract 1
108090000069 P-type ATPases Proteins 0.000 abstract 1
102000003697 P-type ATPases Human genes 0.000 abstract 1
208000016222 Pancreatic disease Diseases 0.000 abstract 1
102000011040 TRPV Cation Channels Human genes 0.000 abstract 1
108010062740 TRPV Cation Channels Proteins 0.000 abstract 1
208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
108091022863 bile acid binding Proteins 0.000 abstract 1
102000030904 bile acid binding Human genes 0.000 abstract 1
206010012601 diabetes mellitus Diseases 0.000 abstract 1
201000005577 familial hyperlipidemia Diseases 0.000 abstract 1
208000027866 inflammatory disease Diseases 0.000 abstract 1
208000017169 kidney disease Diseases 0.000 abstract 1
210000005036 nerve Anatomy 0.000 abstract 1
208000015238 neurotic disease Diseases 0.000 abstract 1
208000024691 pancreas disease Diseases 0.000 abstract 1
102000040430 polynucleotide Human genes 0.000 abstract 1
108091033319 polynucleotide Proteins 0.000 abstract 1
239000002157 polynucleotide Substances 0.000 abstract 1
230000003449 preventive effect Effects 0.000 abstract 1
108090000623 proteins and genes Proteins 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
238000012216 screening Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Bioinformatics & Cheminformatics (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Gastroenterology & Hepatology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Zoology (AREA)
Toxicology (AREA)
Urology & Nephrology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Cardiology (AREA)
Endocrinology (AREA)
Pulmonology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Heart & Thoracic Surgery (AREA)
Obesity (AREA)
Hematology (AREA)
Diabetes (AREA)
Vascular Medicine (AREA)
Reproductive Health (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Peptides Or Proteins (AREA)

AT03701099T 2002-01-18 2003-01-16 Natrium abhängiger gallensäure transporter und dessen verwendung ATE458752T1 (de)

Applications Claiming Priority (9)

Application Number	Priority Date	Filing Date	Title
JP2002010840		2002-01-18
JP2002015995		2002-01-24
JP2002025706		2002-02-01
JP2002025662		2002-02-01
JP2002030015		2002-02-06
JP2002033111		2002-02-08
JP2002045058		2002-02-21
JP2002046951		2002-02-22
PCT/JP2003/000311 WO2003062274A1 (fr)	2002-01-18	2003-01-16	Nouvelles protéines et leurs adn

Publications (1)

Publication Number	Publication Date
ATE458752T1 true ATE458752T1 (de)	2010-03-15

Family

ID=27617997

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT03701099T ATE458752T1 (de)	2002-01-18	2003-01-16	Natrium abhängiger gallensäure transporter und dessen verwendung

Country Status (6)

Country	Link
US (2)	US7754856B2 (de)
EP (1)	EP1473303B1 (de)
JP (2)	JP2003310281A (de)
AT (1)	ATE458752T1 (de)
DE (1)	DE60331413D1 (de)
WO (1)	WO2003062274A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20110030077A1 (en) *	2008-02-01	2011-02-03	University Of Rochester	METHODS OF MODULATING THE ORGANIC SOLUTE AND STEROID TRANSPORTER (OSTalpha-OSTbeta) ACTIVITY AND TREATING ASSOCIATED CONDITIONS
CN102099470B (zh)	2008-08-15	2014-11-12	藤仓化成株式会社	用于诊断动脉硬化的多肽标记、用该标记等检测动脉硬化的方法以及用于诊断动脉硬化的试剂盒

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5589358A (en) *	1993-12-29	1996-12-31	Univ Wake Forest	Ileal bile acid transporter compositions and methods
EP1294762A2 (de) *	2000-06-26	2003-03-26	Millennium Pharmaceuticals, Inc.	Menschliche kalziumkanäle (48000; 52920) und deren verwendung
JP2004513618A (ja) *	2000-07-07	2004-05-13	インサイト・ゲノミックス・インコーポレイテッド	輸送体及びイオンチャネル
US20030064369A1 (en)	2000-07-28	2003-04-03	Taupier Raymond J.	Novel proteins and nucleic acids encoding same
EP1320600A1 (de)	2000-08-03	2003-06-25	Incyte Genomics, Inc.	Transporter und ionenkanäle
WO2002033087A2 (en) *	2000-10-17	2002-04-25	Curagen Corporation	Proteins and nucleic acids encoding same
GB2372993A (en)	2000-11-03	2002-09-11	Smithkline Beecham Plc	Vanilloid Receptor 6
EP1379652A2 (de) *	2000-12-01	2004-01-14	Bristol-Myers Squibb Pharma Company	Humane nukleinsäuremoleküle und polypeptide kodierend für einen im rückenmark und gehirn expremierten humanen ionenkanal
US20020119523A1 (en)	2001-01-17	2002-08-29	Millennium Pharmaceuticals, Inc.	67073, a human phospholipid transporter family member and uses therefor
CA2438206A1 (en) *	2001-02-09	2002-10-03	Incyte Genomics, Inc.	Transporters and ion channels
US6709655B2 (en)	2001-02-28	2004-03-23	Instituto Bioclon, S.A. De C.V.	Pharmaceutical composition of F(ab1)2 antibody fragments and a process for the preparation thereof
US20020164627A1 (en) *	2001-03-12	2002-11-07	Wilganowski Nathaniel L.	Novel human transporter proteins and polynucleotides encoding the same
JP2005500028A (ja)	2001-06-13	2005-01-06	ノバルティス　アクチエンゲゼルシャフト	バニロイドレセプター関連核酸およびポリペプチド

2003
- 2003-01-16 AT AT03701099T patent/ATE458752T1/de not_active IP Right Cessation
- 2003-01-16 JP JP2003007724A patent/JP2003310281A/ja active Pending
- 2003-01-16 DE DE60331413T patent/DE60331413D1/de not_active Expired - Lifetime
- 2003-01-16 WO PCT/JP2003/000311 patent/WO2003062274A1/ja not_active Ceased
- 2003-01-16 EP EP03701099A patent/EP1473303B1/de not_active Expired - Lifetime
- 2003-01-16 US US10/501,566 patent/US7754856B2/en not_active Expired - Fee Related
2009
- 2009-11-16 US US12/619,164 patent/US20100311075A1/en not_active Abandoned
- 2009-11-30 JP JP2009271307A patent/JP2010051322A/ja not_active Withdrawn

Also Published As

Publication number	Publication date
JP2010051322A (ja)	2010-03-11
US20060234924A1 (en)	2006-10-19
WO2003062274A1 (fr)	2003-07-31
EP1473303A1 (de)	2004-11-03
EP1473303B1 (de)	2010-02-24
US7754856B2 (en)	2010-07-13
DE60331413D1 (de)	2010-04-08
US20100311075A1 (en)	2010-12-09
EP1473303A4 (de)	2006-01-04
JP2003310281A (ja)	2003-11-05

Legal Events

Date	Code	Title	Description
2010-08-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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BRPI0507159A (pt)	2007-06-26	polipeptìdeos em feixe de quatro hélices humanos modificados e seus usos
NO995458D0 (no)	1999-11-08	Humane 12-lignende reseptorproteiner, beslektede reagenser og metoder
EP0911342A4 (de)	2002-11-27	Neues protein und verfahren zu dessen herstellung
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DK1673397T3 (da)	2011-03-07	Fremgangsmåde til fremstilling og evaluering af cytotoksicitet af KIR2DL NK-receptorer antistoffer
EP1427744A4 (de)	2005-12-07	System zur antikörperexpression und- synthese
EP1067182A8 (de)	2003-08-27	Sekretorische- oder Membranproteine
DE60039515D1 (de)	2008-08-28	Zusammensetzung für ersatz für knochentransplantat
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Gensure et al.	2001	Multiple sites of contact between the carboxyl-terminal binding domain of PTHrP-(1–36) analogs and the amino-terminal extracellular domain of the PTH/PTHrP receptor identified by photoaffinity cross-linking
AR029642A1 (es)	2003-07-10	Una molecula de adn aislada que codifica un ligando denominado fhm que pertenece a la familia de supergenes de ligandos de tnf, polipeptidos de fhm, anticuerpos que conjugan fhm, materiales que integran dicha molecula y metodos de uso de dichas moleculas, metodos y compuestos farmaceuticos, metodos
PE20061444A1 (es)	2007-01-15	Anticuerpo anti-mcp-1, composiciones, metodos y usos
WO2000015826A3 (en)	2000-11-09	Leptin induced genes
IS5008A (is)	1999-03-23	C-peptíð insúlíns
BR9911978A (pt)	2001-03-27	Feniluracilas substituìdas
ATE458752T1 (de)	2010-03-15	Natrium abhängiger gallensäure transporter und dessen verwendung
Yun et al.	2007	NF-κB regulates Lef1 gene expression in chondrocytes