ATE458828T1 - Systeme und verfahren zur auswertung der wirksamkeit von enzymen - Google Patents
Systeme und verfahren zur auswertung der wirksamkeit von enzymenInfo
- Publication number
- ATE458828T1 ATE458828T1 AT05812911T AT05812911T ATE458828T1 AT E458828 T1 ATE458828 T1 AT E458828T1 AT 05812911 T AT05812911 T AT 05812911T AT 05812911 T AT05812911 T AT 05812911T AT E458828 T1 ATE458828 T1 AT E458828T1
- Authority
- AT
- Austria
- Prior art keywords
- sensor
- sensors
- patient
- enzymatic
- competency
- Prior art date
Links
- 230000002255 enzymatic effect Effects 0.000 abstract 3
- 210000001124 body fluid Anatomy 0.000 abstract 2
- 230000007547 defect Effects 0.000 abstract 2
- 206010061623 Adverse drug reaction Diseases 0.000 abstract 1
- 108091023037 Aptamer Proteins 0.000 abstract 1
- 208000030453 Drug-Related Side Effects and Adverse reaction Diseases 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 238000003491 array Methods 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000009088 enzymatic function Effects 0.000 abstract 1
- 239000000446 fuel Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229920000344 molecularly imprinted polymer Polymers 0.000 abstract 1
- 230000007310 pathophysiology Effects 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US61151404P | 2004-09-20 | 2004-09-20 | |
| PCT/US2005/033883 WO2006034370A2 (en) | 2004-09-20 | 2005-09-20 | Systems and methods for evaluating enzyme competency |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE458828T1 true ATE458828T1 (de) | 2010-03-15 |
Family
ID=35733996
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05812911T ATE458828T1 (de) | 2004-09-20 | 2005-09-20 | Systeme und verfahren zur auswertung der wirksamkeit von enzymen |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090005270A1 (de) |
| EP (1) | EP1805323B1 (de) |
| JP (1) | JP2008513026A (de) |
| AT (1) | ATE458828T1 (de) |
| DE (1) | DE602005019600D1 (de) |
| WO (1) | WO2006034370A2 (de) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1877554A1 (de) * | 2005-04-16 | 2008-01-16 | Otsuka Pharmaceutical Co., Ltd. | Verfahren und zusammensetzung zur bewertung der aktivität des cytochrom-p450-isoenzyms 2d6 unter verwendung eines atemtests |
| US7833744B2 (en) * | 2006-09-01 | 2010-11-16 | Cambridge Isotope Laboratories, Inc. | Methods to evaluate cytochrome P450 2C19 isoenzyme activity using a breath test |
| US7709264B2 (en) * | 2006-09-21 | 2010-05-04 | Philip Morris Usa Inc. | Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines |
| US20120143515A1 (en) * | 2006-09-28 | 2012-06-07 | Smiths Detection Inc. | Multi-detector gas identification system |
| US20100255598A1 (en) * | 2007-02-22 | 2010-10-07 | Melker Richard J | Medication Adherence Monitoring System |
| US8673267B2 (en) | 2009-03-02 | 2014-03-18 | Massachusetts Institute Of Technology | Methods and products for in vivo enzyme profiling |
| JP6245990B2 (ja) | 2011-03-15 | 2017-12-13 | マサチューセッツ インスティテュート オブ テクノロジー | 同位体によりコード化されたレポーターによる多重検出 |
| US10492009B2 (en) * | 2012-05-07 | 2019-11-26 | Starkey Laboratories, Inc. | Hearing aid with distributed processing in ear piece |
| ES2877551T3 (es) | 2013-04-24 | 2021-11-17 | Fresenius Kabi Deutschland Gmbh | Procedimiento de funcionamiento de un dispositivo de control para controlar un dispositivo de infusión |
| JP6847660B2 (ja) | 2013-06-07 | 2021-03-24 | マサチューセッツ インスティテュート オブ テクノロジー | リガンドをコードする合成バイオマーカーのアフィニティベースの検出 |
| EP3440013A4 (de) | 2016-04-08 | 2021-03-17 | Massachusetts Institute of Technology | Verfahren zur spezifischen profilierung der protease-aktivität an lymphknoten |
| WO2017193070A1 (en) | 2016-05-05 | 2017-11-09 | Massachusetts Institute Of Technology | Methods and uses for remotely triggered protease activity measurements |
| WO2018044806A1 (en) * | 2016-08-31 | 2018-03-08 | Empire Technology Development Llc | Food items and sensor devices |
| CA3059358A1 (en) | 2017-04-07 | 2018-10-11 | Massachusetts Institute Of Technology | Methods to spatially profile protease activity in tissue and sections |
| WO2019173332A1 (en) * | 2018-03-05 | 2019-09-12 | Massachusetts Institute Of Technology | Inhalable nanosensors with volatile reporters and uses thereof |
| GB201808062D0 (en) * | 2018-05-17 | 2018-07-04 | Owlstone Med Ltd | Method to evaluate metabolic activity of liver enzymes |
| GB201814350D0 (en) * | 2018-09-04 | 2018-10-17 | Owlstone Med Ltd | Diagnosis of cancer |
| US12173349B2 (en) | 2018-09-25 | 2024-12-24 | Massachusetts Institute Of Technology | Lung protease nanosensors and uses thereof |
| US11835522B2 (en) | 2019-01-17 | 2023-12-05 | Massachusetts Institute Of Technology | Sensors for detecting and imaging of cancer metastasis |
| JP7745904B2 (ja) * | 2020-05-29 | 2025-09-30 | ソムナス サイエンティフィック エルティーディー | プロポフォールセンサ |
| US11535596B2 (en) * | 2020-08-28 | 2022-12-27 | Center For Neurologic Study | Analogs of dextromethorphan with balanced receptor activities |
| WO2022271882A1 (en) * | 2021-06-22 | 2022-12-29 | Northwestern University | Multiplexed antigen-based detection of sars-cov-2 and other diseases using nanomechanical sensors |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5100779A (en) * | 1988-10-04 | 1992-03-31 | Watkins Paul B | Method for determining function of a unique cytochrome P-450 activity |
| US5962335A (en) * | 1997-01-03 | 1999-10-05 | Oridion Medical Ltd. | Breath test for detection of drug metabolism |
| US6284219B1 (en) * | 1998-06-30 | 2001-09-04 | Phenome Sciences Inc. | In vivo determination of metabolic function for use in therapy management |
| US6981947B2 (en) * | 2002-01-22 | 2006-01-03 | University Of Florida Research Foundation, Inc. | Method and apparatus for monitoring respiratory gases during anesthesia |
| US7104963B2 (en) * | 2002-01-22 | 2006-09-12 | University Of Florida Research Foundation, Inc. | Method and apparatus for monitoring intravenous (IV) drug concentration using exhaled breath |
| US20050054942A1 (en) * | 2002-01-22 | 2005-03-10 | Melker Richard J. | System and method for therapeutic drug monitoring |
| GB0106923D0 (en) * | 2001-03-20 | 2001-05-09 | Univ Dundee | Liver function test |
| US7220387B2 (en) * | 2002-07-23 | 2007-05-22 | Apieron Biosystems Corp. | Disposable sensor for use in measuring an analyte in a gaseous sample |
-
2005
- 2005-09-20 US US11/578,323 patent/US20090005270A1/en not_active Abandoned
- 2005-09-20 JP JP2007532655A patent/JP2008513026A/ja active Pending
- 2005-09-20 WO PCT/US2005/033883 patent/WO2006034370A2/en not_active Ceased
- 2005-09-20 AT AT05812911T patent/ATE458828T1/de not_active IP Right Cessation
- 2005-09-20 DE DE602005019600T patent/DE602005019600D1/de not_active Expired - Lifetime
- 2005-09-20 EP EP05812911A patent/EP1805323B1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1805323B1 (de) | 2010-02-24 |
| DE602005019600D1 (de) | 2010-04-08 |
| EP1805323A2 (de) | 2007-07-11 |
| WO2006034370A2 (en) | 2006-03-30 |
| JP2008513026A (ja) | 2008-05-01 |
| WO2006034370A3 (en) | 2006-04-20 |
| US20090005270A1 (en) | 2009-01-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |