ATE458828T1 - Systeme und verfahren zur auswertung der wirksamkeit von enzymen - Google Patents

Systeme und verfahren zur auswertung der wirksamkeit von enzymen

Info

Publication number
ATE458828T1
ATE458828T1 AT05812911T AT05812911T ATE458828T1 AT E458828 T1 ATE458828 T1 AT E458828T1 AT 05812911 T AT05812911 T AT 05812911T AT 05812911 T AT05812911 T AT 05812911T AT E458828 T1 ATE458828 T1 AT E458828T1
Authority
AT
Austria
Prior art keywords
sensor
sensors
patient
enzymatic
competency
Prior art date
Application number
AT05812911T
Other languages
English (en)
Inventor
Richard Melker
Timothy Morey
Laszlo Prokai
Donn Dennis
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Application granted granted Critical
Publication of ATE458828T1 publication Critical patent/ATE458828T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
AT05812911T 2004-09-20 2005-09-20 Systeme und verfahren zur auswertung der wirksamkeit von enzymen ATE458828T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US61151404P 2004-09-20 2004-09-20
PCT/US2005/033883 WO2006034370A2 (en) 2004-09-20 2005-09-20 Systems and methods for evaluating enzyme competency

Publications (1)

Publication Number Publication Date
ATE458828T1 true ATE458828T1 (de) 2010-03-15

Family

ID=35733996

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05812911T ATE458828T1 (de) 2004-09-20 2005-09-20 Systeme und verfahren zur auswertung der wirksamkeit von enzymen

Country Status (6)

Country Link
US (1) US20090005270A1 (de)
EP (1) EP1805323B1 (de)
JP (1) JP2008513026A (de)
AT (1) ATE458828T1 (de)
DE (1) DE602005019600D1 (de)
WO (1) WO2006034370A2 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2606136C (en) * 2005-04-16 2014-07-29 Otsuka Pharmaceutical Co., Ltd. Method and composition to evaluate cytochrome p450 2d6 isoenzyme activity using a breath test
US7833744B2 (en) * 2006-09-01 2010-11-16 Cambridge Isotope Laboratories, Inc. Methods to evaluate cytochrome P450 2C19 isoenzyme activity using a breath test
US7709264B2 (en) * 2006-09-21 2010-05-04 Philip Morris Usa Inc. Handheld microcantilever-based sensor for detecting tobacco-specific nitrosamines
US20120143515A1 (en) * 2006-09-28 2012-06-07 Smiths Detection Inc. Multi-detector gas identification system
JP2010519553A (ja) * 2007-02-22 2010-06-03 ユニバーシティ オブ フロリダ リサーチファウンデーション インコーポレイティッド 服薬遵守モニタリングシステム
EP4032538A3 (de) 2009-03-02 2022-10-26 Massachusetts Institute of Technology Verfahren und produkte zur in-vivo-enzymprofilierung
ES2881535T3 (es) 2011-03-15 2021-11-29 Massachusetts Inst Technology Detección multiplexada con indicadores codificados con isótopos
DK2663095T3 (da) * 2012-05-07 2016-02-01 Starkey Lab Inc Høreapparat med fordelt bearbejdning i øreprop
WO2014173558A1 (en) 2013-04-24 2014-10-30 Fresenius Kabi Deutschland Gmbh Method of operating a control device for controlling an infusion device
JP6847660B2 (ja) 2013-06-07 2021-03-24 マサチューセッツ インスティテュート オブ テクノロジー リガンドをコードする合成バイオマーカーのアフィニティベースの検出
EP3440013A4 (de) 2016-04-08 2021-03-17 Massachusetts Institute of Technology Verfahren zur spezifischen profilierung der protease-aktivität an lymphknoten
WO2017193070A1 (en) 2016-05-05 2017-11-09 Massachusetts Institute Of Technology Methods and uses for remotely triggered protease activity measurements
WO2018044806A1 (en) * 2016-08-31 2018-03-08 Empire Technology Development Llc Food items and sensor devices
AU2018248327B2 (en) 2017-04-07 2024-10-10 Massachusetts Institute Of Technology Methods to spatially profile protease activity in tissue and sections
WO2019173332A1 (en) * 2018-03-05 2019-09-12 Massachusetts Institute Of Technology Inhalable nanosensors with volatile reporters and uses thereof
GB201808062D0 (en) * 2018-05-17 2018-07-04 Owlstone Med Ltd Method to evaluate metabolic activity of liver enzymes
GB201814350D0 (en) 2018-09-04 2018-10-17 Owlstone Med Ltd Diagnosis of cancer
EP3856921B1 (de) 2018-09-25 2026-04-29 Massachusetts Institute Of Technology Lungenprotease nanosensoren und deren verwendungen
EP3911753A1 (de) 2019-01-17 2021-11-24 Massachusetts Institute of Technology Sensoren zur erfassung und abbildung von krebsmetastasen
JP7745904B2 (ja) * 2020-05-29 2025-09-30 ソムナス サイエンティフィック エルティーディー プロポフォールセンサ
US11535596B2 (en) * 2020-08-28 2022-12-27 Center For Neurologic Study Analogs of dextromethorphan with balanced receptor activities
WO2022271882A1 (en) * 2021-06-22 2022-12-29 Northwestern University Multiplexed antigen-based detection of sars-cov-2 and other diseases using nanomechanical sensors

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5100779A (en) * 1988-10-04 1992-03-31 Watkins Paul B Method for determining function of a unique cytochrome P-450 activity
US5962335A (en) * 1997-01-03 1999-10-05 Oridion Medical Ltd. Breath test for detection of drug metabolism
US6284219B1 (en) * 1998-06-30 2001-09-04 Phenome Sciences Inc. In vivo determination of metabolic function for use in therapy management
US6981947B2 (en) * 2002-01-22 2006-01-03 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring respiratory gases during anesthesia
US7104963B2 (en) * 2002-01-22 2006-09-12 University Of Florida Research Foundation, Inc. Method and apparatus for monitoring intravenous (IV) drug concentration using exhaled breath
US20050054942A1 (en) * 2002-01-22 2005-03-10 Melker Richard J. System and method for therapeutic drug monitoring
GB0106923D0 (en) * 2001-03-20 2001-05-09 Univ Dundee Liver function test
US7220387B2 (en) * 2002-07-23 2007-05-22 Apieron Biosystems Corp. Disposable sensor for use in measuring an analyte in a gaseous sample

Also Published As

Publication number Publication date
US20090005270A1 (en) 2009-01-01
EP1805323A2 (de) 2007-07-11
JP2008513026A (ja) 2008-05-01
EP1805323B1 (de) 2010-02-24
WO2006034370A2 (en) 2006-03-30
DE602005019600D1 (de) 2010-04-08
WO2006034370A3 (en) 2006-04-20

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