ATE459004T1 - Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung - Google Patents

Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung

Info

Publication number
ATE459004T1
ATE459004T1 AT05010407T AT05010407T ATE459004T1 AT E459004 T1 ATE459004 T1 AT E459004T1 AT 05010407 T AT05010407 T AT 05010407T AT 05010407 T AT05010407 T AT 05010407T AT E459004 T1 ATE459004 T1 AT E459004T1
Authority
AT
Austria
Prior art keywords
receptor
protein
fprl2
ligand
application
Prior art date
Application number
AT05010407T
Other languages
English (en)
Inventor
Isabelle Migeotte
Marc Parmentier
David Communi
Maryse Brait
Original Assignee
Euroscreen Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Euroscreen Sa filed Critical Euroscreen Sa
Application granted granted Critical
Publication of ATE459004T1 publication Critical patent/ATE459004T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/75—Agonist effect on antigen
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/72—Assays involving receptors, cell surface antigens or cell surface determinants for hormones
    • G01N2333/726—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT05010407T 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung ATE459004T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP04447122 2004-05-14
EP04447231 2004-10-18

Publications (1)

Publication Number Publication Date
ATE459004T1 true ATE459004T1 (de) 2010-03-15

Family

ID=34982585

Family Applications (2)

Application Number Title Priority Date Filing Date
AT08159325T ATE496304T1 (de) 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen-2 (fprl2) g protein gekoppelten rezeptor
AT05010407T ATE459004T1 (de) 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen- 2 (fprl2) g protein gekoppelten rezeptor und dessen anwendung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT08159325T ATE496304T1 (de) 2004-05-14 2005-05-13 Ligand für den formylpeptidrezeptorähnlichen-2 (fprl2) g protein gekoppelten rezeptor

Country Status (7)

Country Link
US (3) US7582416B2 (de)
EP (2) EP2020604B1 (de)
JP (2) JP4694887B2 (de)
AT (2) ATE496304T1 (de)
CA (2) CA2810292C (de)
DE (2) DE602005026072D1 (de)
DK (2) DK2020604T3 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4486256B2 (ja) * 1998-10-22 2010-06-23 ザ・ジェネラル・ホスピタル・コーポレイション 副甲状腺ホルモン（ＰＴＨ）および副甲状腺ホルモン関連ペプチド（ＰＴＨｒＰ）の生物活性ペプチドおよびペプチド誘導体
AU7734800A (en) * 1999-09-29 2001-04-30 General Hospital Corporation, The Polypeptide derivatives of parathyroid hormone (pth)
US7572765B2 (en) * 2001-07-23 2009-08-11 The General Hospital Corporation Conformationally constrained parathyroid hormone (PTH) analogs
AU2003220380A1 (en) * 2003-03-19 2004-11-19 Bristol-Myers Squibb Company CONFORMATIONALLY CONSTRAINED PARATHYROID HORMONES WITH Alpha-HELIX STABILIZERS
EP1653985A4 (de) 2003-07-17 2009-08-05 Gen Hospital Corp Zwangsform-parathormon (pth)-analoga
CA2810292C (en) * 2004-05-14 2015-09-29 Euroscreen S.A. Ligand for g-protein coupled receptor fprl2 and uses thereof
WO2008019062A2 (en) * 2006-08-04 2008-02-14 The General Hospital Corporation Polypeptide derivatives of parathyroid hormone (pth)
US20090004755A1 (en) * 2007-03-23 2009-01-01 Biosite, Incorporated Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
US8221995B2 (en) 2007-03-23 2012-07-17 Seok-Won Lee Methods and compositions for diagnosis and/or prognosis in systemic inflammatory response syndromes
PE20090321A1 (es) 2007-06-04 2009-04-20 Genentech Inc Anticuerpos anti-notch1 nrr, metodo de preparacion y composicion farmaceutica
US20090042869A1 (en) * 2007-06-20 2009-02-12 University Of Utah Research Foundation SIGNAL-DEPENDENT SPLICING OF TISSUE FACTOR PRE-mRNA IN PLATELET CELLS
BRPI0814962B8 (pt) * 2007-08-01 2021-05-25 Chugai Pharmaceutical Co Ltd métodos in vitro para determinar se um composto candidato é um agonista de longa duração ou de curta duração de um receptor acoplado à proteína g, polipeptídeo, seu uso e composição farmacêutica
CN102239414A (zh) * 2008-12-04 2011-11-09 赛诺菲-安万特 牵涉血红素结合蛋白1的方法和用途
JP5510945B2 (ja) 2009-05-18 2014-06-04 アクテリオン ファーマシューティカルズ リミテッド Ａｌｘ受容体及び／又はｆｐｒｌ２アゴニストとしての架橋スピロ［２．４］ヘプタン誘導体
WO2011073918A2 (en) 2009-12-16 2011-06-23 Actelion Pharmaceuticals Ltd Peptides as modulators of fprl1 and/or fprl2
CN103002906B (zh) 2010-05-13 2017-12-29 总医院有限公司 甲状旁腺激素类似物及其应用
CN107810420B (zh) * 2015-06-25 2020-08-14 豪夫迈·罗氏有限公司 用于测定抗体或配体结合和功能的基于细胞的测定

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990005745A1 (en) 1988-11-18 1990-05-31 The General Hospital Corporation A cAMP-RESPONSIVE TRANSCRIPTIONAL ENHANCER BINDING PROTEIN
JP3540315B2 (ja) 1991-09-23 2004-07-07 メディカル リサーチ カウンシル キメラ抗体の製造−組合せアプローチ
DE614989T1 (de) 1993-02-17 1995-09-28 Morphosys Proteinoptimierung Verfahren für in vivo Selektion von Ligandenbindende Proteine.
EP0859841B1 (de) 1995-08-18 2002-06-19 MorphoSys AG Protein-/(poly)peptidbibliotheken
US7119190B2 (en) * 1997-04-14 2006-10-10 Arena Pharmaceuticals, Inc. Endogenous and non-endogenous versions of human G protein-coupled receptors
US6872538B1 (en) 1998-07-06 2005-03-29 Euroscreen S.A. High-throughput screening diagnostic and/or dosage method of an agonist and/or an antagonist for a calcium-coupled receptor
EP1214337A2 (de) * 1999-09-15 2002-06-19 Incyte Genomics, Inc. Proteine die mit zelldifferenzierung assoziiert sind
US6436703B1 (en) * 2000-03-31 2002-08-20 Hyseq, Inc. Nucleic acids and polypeptides
JP4184875B2 (ja) * 2002-06-14 2008-11-19 武田薬品工業株式会社 新規スクリーニング方法
CA2810292C (en) * 2004-05-14 2015-09-29 Euroscreen S.A. Ligand for g-protein coupled receptor fprl2 and uses thereof

Also Published As

Publication number Publication date
JP2011078437A (ja) 2011-04-21
JP5314061B2 (ja) 2013-10-16
CA2810292A1 (en) 2005-11-14
DK1607745T3 (da) 2010-06-14
CA2504920A1 (en) 2005-11-14
DK2020604T3 (da) 2011-05-16
EP2020604A1 (de) 2009-02-04
EP1607745A3 (de) 2006-07-26
JP4694887B2 (ja) 2011-06-08
US20100009406A1 (en) 2010-01-14
JP2006025787A (ja) 2006-02-02
ATE496304T1 (de) 2011-02-15
US7582416B2 (en) 2009-09-01
EP1607745B1 (de) 2010-02-24
DE602005019495D1 (de) 2010-04-08
CA2810292C (en) 2015-09-29
DE602005026072D1 (de) 2011-03-03
EP1607745A2 (de) 2005-12-21
US20060078559A1 (en) 2006-04-13
US20090053739A1 (en) 2009-02-26
US7659251B2 (en) 2010-02-09
US7842795B2 (en) 2010-11-30
EP2020604B1 (de) 2011-01-19
CA2504920C (en) 2014-04-01

Similar Documents

Publication Publication Date Title
DE602005019495D1 (de) Ligand für den Formylpeptidrezeptorähnlichen- 2 (FPRL2) G Protein gekoppelten Rezeptor und dessen Anwendung
GEP20094629B (en) Nogo receptor binding protein
EP1392359A4 (de) Spezifische bindungsproteine und ihre verwendung
WO2006113602A3 (en) Ascorbate binding peptides
ATE446972T1 (de) Il-1 bindende antikörper und fragmente davon
ATE504599T1 (de) Zur aktivierung von rezeptoren fähige fusionspolypeptide
MXPA04008077A (es) Anticuerpos ant-a° y su uso.
WO2005087811A3 (en) Estrogen receptors and methods of use
EA200600042A1 (ru) Способы образования дисульфидных связей и гликозилирования белков и реагенты, применяемые в этих способах
ECSP055849A (es) Anticuerpo ("11c7") anti-nogo a y su uso farmacéutico
WO2004090103A3 (en) Identification of novel nogo-receptors and methods related thereto

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties