ATE460188T1 - Keratin-netzwerke enthaltende wundverbände für gewebedefekte - Google Patents

Keratin-netzwerke enthaltende wundverbände für gewebedefekte

Info

Publication number
ATE460188T1
ATE460188T1 AT03718375T AT03718375T ATE460188T1 AT E460188 T1 ATE460188 T1 AT E460188T1 AT 03718375 T AT03718375 T AT 03718375T AT 03718375 T AT03718375 T AT 03718375T AT E460188 T1 ATE460188 T1 AT E460188T1
Authority
AT
Austria
Prior art keywords
networks
wound dressings
tissue defects
containing keratin
dressings containing
Prior art date
Application number
AT03718375T
Other languages
English (en)
Inventor
Dyke Mark Van
Original Assignee
Keraplast Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/119,477 external-priority patent/US6914126B2/en
Priority claimed from US10/127,523 external-priority patent/US7001987B2/en
Priority claimed from US10/133,885 external-priority patent/US6989437B2/en
Application filed by Keraplast Tech Ltd filed Critical Keraplast Tech Ltd
Application granted granted Critical
Publication of ATE460188T1 publication Critical patent/ATE460188T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • A61K38/015—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen from keratin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4741—Keratin; Cytokeratin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C08G77/452—Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences
    • C08G77/455—Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences containing polyamide, polyesteramide or polyimide sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Dermatology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Colloid Chemistry (AREA)
AT03718375T 2002-04-10 2003-04-10 Keratin-netzwerke enthaltende wundverbände für gewebedefekte ATE460188T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/119,477 US6914126B2 (en) 2002-04-10 2002-04-10 Methods for producing, films comprising, and methods for using heterogenous crosslinked protein networks
US10/127,523 US7001987B2 (en) 2002-04-22 2002-04-22 Hydrogel with controllable mechanical, chemical, and biological properties and method for making same
US10/133,885 US6989437B2 (en) 2002-04-10 2002-04-26 Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks
US39395802P 2002-07-05 2002-07-05
PCT/US2003/011364 WO2003086491A2 (en) 2002-04-10 2003-04-10 Tissue defect dressings comprising a keratin network

Publications (1)

Publication Number Publication Date
ATE460188T1 true ATE460188T1 (de) 2010-03-15

Family

ID=29255535

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03718375T ATE460188T1 (de) 2002-04-10 2003-04-10 Keratin-netzwerke enthaltende wundverbände für gewebedefekte

Country Status (10)

Country Link
EP (2) EP1495048B1 (de)
JP (2) JP2005528938A (de)
AT (1) ATE460188T1 (de)
AU (5) AU2003221916A1 (de)
CA (2) CA2482262A1 (de)
DE (1) DE60331638D1 (de)
DK (1) DK1495048T3 (de)
ES (1) ES2460926T3 (de)
NZ (2) NZ536159A (de)
WO (4) WO2003086491A2 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2004298392A1 (en) * 2003-12-19 2005-06-30 Keratec Limited Wound care products containing keratin
JP4624355B2 (ja) * 2004-07-30 2011-02-02 パナソニック株式会社 無線送信装置および無線送信方法
US7439012B2 (en) 2004-08-17 2008-10-21 Wake Forest University Health Sciences Ambient stored blood plasma expanders containing keratose
US8920827B2 (en) 2005-10-21 2014-12-30 Wake Forest University Health Sciences Keratin bioceramic compositions
EP1991253B1 (de) 2006-02-10 2013-07-31 Wake Forest University Health Sciences Nervenregenerierung mit keratinbiomaterial
US8273702B2 (en) 2006-02-17 2012-09-25 Wake Forest University Health Sciences Wound healing compositions containing keratin biomaterials
JP2009527274A (ja) * 2006-02-17 2009-07-30 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ ケラチン医用生体材料から形成されるコーティングおよび生体用インプラント
WO2008130607A2 (en) * 2007-04-17 2008-10-30 Wake Forest University Health Sciences Wound healing compositions containing keratin biomaterials
WO2008058323A1 (en) 2006-11-13 2008-05-22 The University Of Sydney Use of tropoelastin for repair or restoration of tissue
GB0622694D0 (en) * 2006-11-14 2006-12-27 Serentis Ltd Use of opioid compounds in wound healing
US9068162B2 (en) 2007-08-17 2015-06-30 Wake Forest University Health Sciences Keratin biomaterials for cell culture and methods of use
US9045600B2 (en) 2009-05-13 2015-06-02 Keraplast Technologies, Ltd. Biopolymer materials
BRPI1010564A2 (pt) 2009-06-22 2016-03-15 Borealis Ag "uso de um tubo e método de transporte de água"
CA2791386C (en) 2010-03-05 2023-10-31 Wake Forest University Health Sciences Keratin gel composition for controlled delivery of a compound
US8545893B2 (en) 2010-03-08 2013-10-01 Wake Forest University Health Sciences Keratin biomaterials for treatment of ischemia
CA2818166C (en) 2010-11-17 2019-04-30 Wake Forest University Health Sciences Keratin compositions for treatment of bone deficiency or injury
EP2744820B1 (de) 2011-08-17 2018-07-25 Keranetics LLC Verfahren zur extraktion von keratinischen proteinen
US9700631B2 (en) 2011-08-17 2017-07-11 KeraNetics, LLC Low protein percentage gelling compositions
US9827245B2 (en) 2013-03-15 2017-11-28 KeraNetics, LLC Keratin compositions comprising halofuginone
US9783905B2 (en) * 2014-12-30 2017-10-10 Rohm and Haas Electronic Mateirals LLC Reaction products of amino acids and epoxies
CN105126148B (zh) * 2015-08-03 2018-03-23 广东泰宝医疗科技股份有限公司 一种可视银释放敷料及其制备方法
CN114681673B (zh) * 2020-12-31 2023-05-23 杭州启明医疗器械股份有限公司 抗折痕的脱水交联生物材料及其制备方法和应用
US20250090719A1 (en) * 2021-07-30 2025-03-20 Regents Of The University Of Minnesota Biomaterials for embolization and drug delivery

Family Cites Families (22)

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Publication number Priority date Publication date Assignee Title
NL274938A (de) * 1961-02-22
BE758986A (fr) * 1969-11-18 1971-04-30 Iws Nominee Co Ltd Procede de foulage de tissus textiles
DE2364525A1 (de) * 1973-12-24 1975-07-03 Henkel & Cie Gmbh Neue n-polyhydroxyalkyl-aminosaeuren, deren herstellung, sowie diese enthaltende hautpflege- und hautschutzmittel
EP0097907A3 (de) * 1982-06-25 1985-01-09 Flow General, Inc. Mikroträger für Zellkultur
US4474694A (en) * 1982-11-08 1984-10-02 Ralston Purina Company Modified protein adhesive binder and method of producing
JPS59155248A (ja) * 1983-02-22 1984-09-04 テルモ株式会社 被覆膜およびその製法
US4795629A (en) * 1987-07-06 1989-01-03 Chesebrough-Pond's Inc. Crosslinking of hair thiols using cystamine
JPH0725778B2 (ja) * 1987-10-21 1995-03-22 花王株式会社 リン酸エステル、その製造法およびそれを含有する洗浄剤組成物
GB9123251D0 (en) * 1991-11-01 1991-12-18 Croda Int Plc Protein-silicone copolymers
FR2692582B1 (fr) * 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
US5300285A (en) * 1992-10-13 1994-04-05 Dow Corning Corporation Permanent waving with silicones
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US5932552A (en) * 1997-11-26 1999-08-03 Keraplast Technologies Ltd. Keratin-based hydrogel for biomedical applications and method of production
US5948432A (en) * 1997-11-26 1999-09-07 Keraplast Technologies Ltd. Keratin-based sheet material for biomedical applications and method of production
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Also Published As

Publication number Publication date
CA2482262A1 (en) 2003-10-23
WO2003087156A3 (en) 2004-09-02
EP1495048A2 (de) 2005-01-12
EP1495048B1 (de) 2014-03-05
AU2003224926A1 (en) 2003-10-27
EP1494728A2 (de) 2005-01-12
AU2003221916A1 (en) 2003-10-27
WO2003087197A1 (en) 2003-10-23
JP2006508027A (ja) 2006-03-09
ES2460926T3 (es) 2014-05-16
WO2003087195A2 (en) 2003-10-23
WO2003086491A2 (en) 2003-10-23
AU2003221870B2 (en) 2009-06-04
DE60331638D1 (de) 2010-04-22
WO2003086491B1 (en) 2004-04-01
NZ536158A (en) 2009-12-24
JP2005528938A (ja) 2005-09-29
NZ536159A (en) 2006-05-26
AU2003221870A1 (en) 2003-10-27
EP1494728B1 (de) 2010-03-10
WO2003087195A3 (en) 2004-07-15
CA2482215A1 (en) 2003-10-23
DK1495048T3 (da) 2014-05-05
AU2009200774A1 (en) 2009-03-19
WO2003086491A3 (en) 2004-02-26
AU2003234721A8 (en) 2003-10-27
WO2003087156A2 (en) 2003-10-23
AU2003234721A1 (en) 2003-10-27

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