ATE460188T1 - Keratin-netzwerke enthaltende wundverbände für gewebedefekte - Google Patents

Keratin-netzwerke enthaltende wundverbände für gewebedefekte

Info

Publication number
ATE460188T1
ATE460188T1 AT03718375T AT03718375T ATE460188T1 AT E460188 T1 ATE460188 T1 AT E460188T1 AT 03718375 T AT03718375 T AT 03718375T AT 03718375 T AT03718375 T AT 03718375T AT E460188 T1 ATE460188 T1 AT E460188T1
Authority
AT
Austria
Prior art keywords
networks
wound dressings
tissue defects
containing keratin
dressings containing
Prior art date
Application number
AT03718375T
Other languages
English (en)
Inventor
Dyke Mark Van
Original Assignee
Keraplast Tech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/119,477 external-priority patent/US6914126B2/en
Priority claimed from US10/127,523 external-priority patent/US7001987B2/en
Priority claimed from US10/133,885 external-priority patent/US6989437B2/en
Application filed by Keraplast Tech Ltd filed Critical Keraplast Tech Ltd
Application granted granted Critical
Publication of ATE460188T1 publication Critical patent/ATE460188T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/01—Hydrolysed proteins; Derivatives thereof
    • A61K38/012—Hydrolysed proteins; Derivatives thereof from animals
    • A61K38/014—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen
    • A61K38/015—Hydrolysed proteins; Derivatives thereof from animals from connective tissue peptides, e.g. gelatin, collagen from keratin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0028—Polypeptides; Proteins; Degradation products thereof
    • A61L26/0047—Specific proteins or polypeptides not covered by groups A61L26/0033 - A61L26/0042
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4741—Keratin; Cytokeratin
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G77/00—Macromolecular compounds obtained by reactions forming a linkage containing silicon with or without sulfur, nitrogen, oxygen or carbon in the main chain of the macromolecule
    • C08G77/42—Block-or graft-polymers containing polysiloxane sequences
    • C08G77/452—Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences
    • C08G77/455—Block-or graft-polymers containing polysiloxane sequences containing nitrogen-containing sequences containing polyamide, polyesteramide or polyimide sequences
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
    • C08H1/00—Macromolecular products derived from proteins
    • C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Polymers & Plastics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Materials Engineering (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
  • Materials For Medical Uses (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Colloid Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
AT03718375T 2002-04-10 2003-04-10 Keratin-netzwerke enthaltende wundverbände für gewebedefekte ATE460188T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10/119,477 US6914126B2 (en) 2002-04-10 2002-04-10 Methods for producing, films comprising, and methods for using heterogenous crosslinked protein networks
US10/127,523 US7001987B2 (en) 2002-04-22 2002-04-22 Hydrogel with controllable mechanical, chemical, and biological properties and method for making same
US10/133,885 US6989437B2 (en) 2002-04-10 2002-04-26 Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks
US39395802P 2002-07-05 2002-07-05
PCT/US2003/011364 WO2003086491A2 (en) 2002-04-10 2003-04-10 Tissue defect dressings comprising a keratin network

Publications (1)

Publication Number Publication Date
ATE460188T1 true ATE460188T1 (de) 2010-03-15

Family

ID=29255535

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03718375T ATE460188T1 (de) 2002-04-10 2003-04-10 Keratin-netzwerke enthaltende wundverbände für gewebedefekte

Country Status (10)

Country Link
EP (2) EP1495048B1 (de)
JP (2) JP2005528938A (de)
AT (1) ATE460188T1 (de)
AU (5) AU2003221916A1 (de)
CA (2) CA2482215A1 (de)
DE (1) DE60331638D1 (de)
DK (1) DK1495048T3 (de)
ES (1) ES2460926T3 (de)
NZ (2) NZ536158A (de)
WO (4) WO2003087197A1 (de)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4662948B2 (ja) * 2003-12-19 2011-03-30 ケラテク リミテッド ケラチンを含む創傷ケア製品
BRPI0513954A (pt) * 2004-07-30 2008-05-20 Matsushita Electric Industrial Co Ltd transmissor sem fio e método de transmissão sem fio
US7439012B2 (en) 2004-08-17 2008-10-21 Wake Forest University Health Sciences Ambient stored blood plasma expanders containing keratose
US8920827B2 (en) 2005-10-21 2014-12-30 Wake Forest University Health Sciences Keratin bioceramic compositions
EP1991253B1 (de) 2006-02-10 2013-07-31 Wake Forest University Health Sciences Nervenregenerierung mit keratinbiomaterial
US9149566B2 (en) 2006-02-17 2015-10-06 Wake Forest University Health Sciences Coatings and biomedical implants formed from keratin biomaterials
US8273702B2 (en) 2006-02-17 2012-09-25 Wake Forest University Health Sciences Wound healing compositions containing keratin biomaterials
CN101553262A (zh) 2006-11-13 2009-10-07 悉尼大学 原弹性蛋白用于组织修复或恢复的用途
GB0622694D0 (en) * 2006-11-14 2006-12-27 Serentis Ltd Use of opioid compounds in wound healing
JP5868592B2 (ja) * 2007-04-17 2016-02-24 ウェイク・フォレスト・ユニヴァーシティ・ヘルス・サイエンシズ ケラチンバイオマテリアルを含有する創傷治癒組成物
US9068162B2 (en) 2007-08-17 2015-06-30 Wake Forest University Health Sciences Keratin biomaterials for cell culture and methods of use
CN102482319B (zh) 2009-05-13 2015-07-29 凯拉普雷斯特技术有限公司 生物聚合物材料
US9200136B2 (en) 2009-06-22 2015-12-01 Borealis Ag Chlorine dioxide resistant polyethylene pipes, their preparation and use
EP2542564B1 (de) 2010-03-05 2018-05-09 Wake Forest University Health Sciences System für gesteuerte freisetzung
WO2011112575A1 (en) 2010-03-08 2011-09-15 Wake Forest University Health Sciences Keratin biomaterials for treatment of ischemia
CA2818166C (en) 2010-11-17 2019-04-30 Wake Forest University Health Sciences Keratin compositions for treatment of bone deficiency or injury
EP2744480B8 (de) 2011-08-17 2019-06-26 Keratin Biosciences, Inc. Proteinarme gelierungszusammensetzungen
US10385095B2 (en) 2011-08-17 2019-08-20 Keratin Biosciences, Inc Methods for extracting keratin proteins
US9827245B2 (en) 2013-03-15 2017-11-28 KeraNetics, LLC Keratin compositions comprising halofuginone
US9783905B2 (en) * 2014-12-30 2017-10-10 Rohm and Haas Electronic Mateirals LLC Reaction products of amino acids and epoxies
CN105126148B (zh) * 2015-08-03 2018-03-23 广东泰宝医疗科技股份有限公司 一种可视银释放敷料及其制备方法
CN114681673B (zh) * 2020-12-31 2023-05-23 杭州启明医疗器械股份有限公司 抗折痕的脱水交联生物材料及其制备方法和应用
US20250090719A1 (en) * 2021-07-30 2025-03-20 Regents Of The University Of Minnesota Biomaterials for embolization and drug delivery

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL274938A (de) * 1961-02-22
BE758986A (fr) * 1969-11-18 1971-04-30 Iws Nominee Co Ltd Procede de foulage de tissus textiles
DE2364525A1 (de) * 1973-12-24 1975-07-03 Henkel & Cie Gmbh Neue n-polyhydroxyalkyl-aminosaeuren, deren herstellung, sowie diese enthaltende hautpflege- und hautschutzmittel
EP0097907A3 (de) * 1982-06-25 1985-01-09 Flow General, Inc. Mikroträger für Zellkultur
US4474694A (en) * 1982-11-08 1984-10-02 Ralston Purina Company Modified protein adhesive binder and method of producing
JPS59155248A (ja) * 1983-02-22 1984-09-04 テルモ株式会社 被覆膜およびその製法
US4795629A (en) * 1987-07-06 1989-01-03 Chesebrough-Pond's Inc. Crosslinking of hair thiols using cystamine
JPH0725778B2 (ja) * 1987-10-21 1995-03-22 花王株式会社 リン酸エステル、その製造法およびそれを含有する洗浄剤組成物
GB9123251D0 (en) * 1991-11-01 1991-12-18 Croda Int Plc Protein-silicone copolymers
FR2692582B1 (fr) * 1992-06-18 1998-09-18 Flamel Tech Sa Nouveaux derives reticulables de collagene, leur procede d'obtention et leur application a la preparation de biomateriaux.
US5300285A (en) * 1992-10-13 1994-04-05 Dow Corning Corporation Permanent waving with silicones
US5505952A (en) * 1994-04-19 1996-04-09 United States Surgical Corporation Modified synthetic cross-linked amino acid polymers and medical devices formed therefrom
US6214331B1 (en) * 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6352699B1 (en) * 1997-04-04 2002-03-05 L'oreal Cosmetic or dermatological composition forming, on a keratin substrate, a film in cross-linked hybrid material
EP0881247B1 (de) * 1997-05-29 2004-02-11 Rohm And Haas Company Vernetzte Polyaminsäure und deren Verfahren zur Herstellung
US5948432A (en) * 1997-11-26 1999-09-07 Keraplast Technologies Ltd. Keratin-based sheet material for biomedical applications and method of production
US6110487A (en) * 1997-11-26 2000-08-29 Keraplast Technologies Ltd. Method of making porous keratin scaffolds and products of same
US5932552A (en) * 1997-11-26 1999-08-03 Keraplast Technologies Ltd. Keratin-based hydrogel for biomedical applications and method of production
US7662409B2 (en) * 1998-09-25 2010-02-16 Gel-Del Technologies, Inc. Protein matrix materials, devices and methods of making and using thereof
US6371984B1 (en) * 1999-09-13 2002-04-16 Keraplast Technologies, Ltd. Implantable prosthetic or tissue expanding device
EP1403304B1 (de) * 2001-05-30 2008-08-27 Keiichi Miyamoto Vernetztes elastin und verfahren zu deren herstellung
US6989437B2 (en) * 2002-04-10 2006-01-24 Keraplast Technologies, Ltd. Methods for producing, films comprising, and methods for using heterogeneous crosslinked protein networks

Also Published As

Publication number Publication date
JP2006508027A (ja) 2006-03-09
NZ536159A (en) 2006-05-26
WO2003087195A3 (en) 2004-07-15
AU2003221870A1 (en) 2003-10-27
NZ536158A (en) 2009-12-24
CA2482215A1 (en) 2003-10-23
AU2009200774A1 (en) 2009-03-19
ES2460926T3 (es) 2014-05-16
EP1494728B1 (de) 2010-03-10
JP2005528938A (ja) 2005-09-29
AU2003234721A8 (en) 2003-10-27
AU2003221916A1 (en) 2003-10-27
WO2003086491A2 (en) 2003-10-23
DE60331638D1 (de) 2010-04-22
EP1495048B1 (de) 2014-03-05
AU2003224926A1 (en) 2003-10-27
AU2003221870B2 (en) 2009-06-04
CA2482262A1 (en) 2003-10-23
WO2003086491B1 (en) 2004-04-01
DK1495048T3 (da) 2014-05-05
WO2003086491A3 (en) 2004-02-26
WO2003087195A2 (en) 2003-10-23
EP1495048A2 (de) 2005-01-12
WO2003087156A3 (en) 2004-09-02
AU2003234721A1 (en) 2003-10-27
WO2003087197A1 (en) 2003-10-23
EP1494728A2 (de) 2005-01-12
WO2003087156A2 (en) 2003-10-23

Similar Documents

Publication Publication Date Title
ATE460188T1 (de) Keratin-netzwerke enthaltende wundverbände für gewebedefekte
BR0113001B1 (pt) processo para produzir um absorvente, uma construção absorvìvel e um material absorvìvel.
NO994877L (no) Kalsilytiske forbindelser
DE60023043D1 (de) (S,S)-Reboxetin zur Behandlung von Inkontinenz
EP1587834A4 (de) Verwendungen von säuger-cytokin; verwandte reagenzien
DE60006361D1 (de) Mehrschichtige prothese zur chirurgischen behandlung von inguinalhernia
SE0003537L (sv) Hudvänligt lim
EA199900162A1 (ru) Ингибиторы клеточной адгезии
ATE552864T1 (de) Therapeutisch aktive wundauflagen, deren herstellung und deren verwendung
PT910412E (pt) Hidrogeis hidrolisaveis para libertacao controlada
AU2002212552A1 (en) Hydrogel wound dressings
DE60326973D1 (de) Bioaktive beschichtung für medizinische vorrichtung mit keratin
ATE318607T1 (de) Heparin-haltiges ophthalmikum
ATE369880T1 (de) Mediziniscer verband
ATE538756T1 (de) Fasern für die behandlung von wunden
DK0955515T3 (da) Væv, især stikbeskyttende væv
DE60212143D1 (de) Verwendung von thrombin-peptidderivaten zur behandlung von chronischen hautulcera
ATE389367T1 (de) Dentales formteil, insbesondere künstlicher zahn
DE59811072D1 (de) Wässrige, vernetzende Polymerdispersionen sowie ihre Verwendung für die Herstellung von wässrigen Klebstoffen
EE200200167A (et) Sünteetiline nahk, meetod selle valmistamiseks ning kasutamine
DE50101479D1 (de) Fluoresceinisothiocyanat-(fitc)-sinistrin, seine herstellung und verwendung
AR033270A1 (es) Dispositivo para la osteosintesis
IS5231A (is) Vefjaþáttur sem hefur áhrif á blóðæðarmyndun
BR0209400A (pt) Composição para cuidado de tecido, processo para o tratamento de tecido, e, uso de uma composição
DE60204614D1 (de) Narbenbildung fördernder hydrokolloidaler Wundverband, welcher Hyaluronsäure und Chondroitinsulfat enthält

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties