ATE460666T1 - Verfahren zur bestimmung der aminosäurensequenz von peptiden - Google Patents

Verfahren zur bestimmung der aminosäurensequenz von peptiden

Info

Publication number
ATE460666T1
ATE460666T1 AT08150294T AT08150294T ATE460666T1 AT E460666 T1 ATE460666 T1 AT E460666T1 AT 08150294 T AT08150294 T AT 08150294T AT 08150294 T AT08150294 T AT 08150294T AT E460666 T1 ATE460666 T1 AT E460666T1
Authority
AT
Austria
Prior art keywords
amino acid
peptide
determining
acid sequence
peptides
Prior art date
Application number
AT08150294T
Other languages
English (en)
Inventor
Albert John Roeland Heck
Shabaza Mohammed
Van Breukelen
Nadia Taouatas
Madalina Mihaela Drugan
Original Assignee
Univ Utrecht Holding Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Utrecht Holding Bv filed Critical Univ Utrecht Holding Bv
Application granted granted Critical
Publication of ATE460666T1 publication Critical patent/ATE460666T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818—Sequencing of polypeptides
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/914—Hydrolases (3)
    • G01N2333/948—Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95—Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643—Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96486—Metalloendopeptidases (3.4.24)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
AT08150294T 2008-01-15 2008-01-15 Verfahren zur bestimmung der aminosäurensequenz von peptiden ATE460666T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP08150294A EP2081025B1 (de) 2008-01-15 2008-01-15 Verfahren zur Bestimmung der Aminosäurensequenz von Peptiden

Publications (1)

Publication Number Publication Date
ATE460666T1 true ATE460666T1 (de) 2010-03-15

Family

ID=39183025

Family Applications (1)

Application Number Title Priority Date Filing Date
AT08150294T ATE460666T1 (de) 2008-01-15 2008-01-15 Verfahren zur bestimmung der aminosäurensequenz von peptiden

Country Status (5)

Country Link
US (1) US8338122B2 (de)
EP (1) EP2081025B1 (de)
AT (1) ATE460666T1 (de)
DE (1) DE602008000796D1 (de)
WO (1) WO2009090188A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE460666T1 (de) 2008-01-15 2010-03-15 Univ Utrecht Holding Bv Verfahren zur bestimmung der aminosäurensequenz von peptiden
EP2885316A1 (de) 2012-08-20 2015-06-24 Merz Pharma GmbH & Co. KGaA Neuartiges verfahren zur herstellung rekombinanter proteine mit einem n-terminalen lysin
CN103852513B (zh) * 2012-11-29 2016-01-06 中国科学院计算技术研究所 一种基于hcd与etd质谱图的肽段从头测序方法及系统
WO2014105858A1 (en) 2012-12-26 2014-07-03 Quest Diagnostics Investments Incorporated C peptide detection by mass spectrometry
EP3057616B1 (de) 2013-10-16 2020-03-11 Outlook Therapeutics, Inc. Pufferformulierungen für verstärkte antikörperstabilität
WO2016118707A1 (en) 2015-01-21 2016-07-28 Oncobiologics, Inc. Modulation of charge variants in a monoclonal antibody composition
JP2019505780A (ja) * 2015-12-30 2019-02-28 フィト エヌフェー 質量分析法に基づく生体高分子の構造決定方法
CN109563161A (zh) 2016-02-03 2019-04-02 安口生物公司 用于提高抗体稳定性的缓冲制剂
AU2017214586A1 (en) * 2016-02-04 2018-08-16 Outlook Therapeutics, Inc. Methods for identifying and analyzing amino acid sequences of proteins
US20190343963A1 (en) * 2016-04-22 2019-11-14 Medimmune Limited Conjugated protease targeting moieties
KR20210045449A (ko) * 2018-08-17 2021-04-26 리제너론 파아마슈티컬스, 인크. 새로운 단백질 서열분석 방법
US11726096B2 (en) * 2018-10-04 2023-08-15 Regeneron Pharmaceuticals, Inc. Fast protein sequencing
AU2019380606B2 (en) 2018-11-15 2026-04-23 Quantum-Si Incorporated Methods and compositions for protein sequencing
US20210148922A1 (en) * 2019-10-28 2021-05-20 Quantum-Si Incorporated Methods of single-polypeptide sequencing and reconstruction
EP4143579A2 (de) 2020-05-20 2023-03-08 Quantum-si Incorporated Verfahren und zusammensetzungen zur proteinsequenzierung
EP4405687A1 (de) * 2021-09-22 2024-07-31 DH Technologies Development Pte. Ltd. Ms/ms-basierte identifizierung von trisulfidbindungen
CN120584285A (zh) * 2023-02-01 2025-09-02 Dh科技发展私人贸易有限公司 用于在大的多肽分析中提高序列覆盖率的系统和方法
CN116930369B (zh) * 2023-07-27 2025-12-26 黑龙江飞鹤乳业有限公司 用于乳蛋白水解多肽分析的方法
CN118033144A (zh) * 2024-01-22 2024-05-14 中国人民解放军军事科学院军事医学研究院 一种基于子离子类型可辨识且子离子全覆盖的直读型蛋白质和蛋白质组精准从头测序方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060141632A1 (en) * 2000-07-25 2006-06-29 The Procter & Gamble Co. New methods and kits for sequencing polypeptides
US20040121477A1 (en) * 2002-12-20 2004-06-24 Thompson Dean R. Method for improving data dependent ion selection in tandem mass spectroscopy of protein digests
US7371514B2 (en) * 2004-07-16 2008-05-13 Agilent Technologies, Inc. Serial derivatization of peptides for de novo sequencing using tandem mass spectrometry
ATE460666T1 (de) 2008-01-15 2010-03-15 Univ Utrecht Holding Bv Verfahren zur bestimmung der aminosäurensequenz von peptiden

Also Published As

Publication number Publication date
EP2081025B1 (de) 2010-03-10
EP2081025A9 (de) 2009-09-30
EP2081025A1 (de) 2009-07-22
DE602008000796D1 (de) 2010-04-22
WO2009090188A1 (en) 2009-07-23
US20100311098A1 (en) 2010-12-09
US8338122B2 (en) 2012-12-25

Similar Documents

Publication Publication Date Title
ATE460666T1 (de) Verfahren zur bestimmung der aminosäurensequenz von peptiden
CN101600959B (zh) 肽和蛋白的定量方法
ATE495447T1 (de) Peptidantikörperdepletion und anwendung zur probenvorbereitung für massenspektrometrie
ATE508361T1 (de) Absolute quantifizierung von proteinen und modifizierten formen davon mittels mehrstufiger massenspektrometrie
Dada et al. Characterization of acidic and basic variants of IgG1 therapeutic monoclonal antibodies based on non‐denaturing IEF fractionation
WO2003074992A3 (en) Phosphorylated proteins and uses related thereto
WO2021236716A3 (en) Methods, systems and kits for polypeptide processing and analysis
US8501487B2 (en) Composition for use as a peptide retention standard and a method of predicting peptide hydrophobicity in liquid chromatography
WO2002097703A3 (en) Method to identify constituent proteins by peptides profiling
EP1736480A1 (de) Künstliches Protein, Verfahren für absolute Quantifizierung der Proteine und seine Benutzung
JP2021534408A5 (de)
EP2517011A4 (de) Srm/mrm-test auf das rezeptorprotein des insulinähnliche wachstumsfaktors 1 (igf-1r)
EA202190550A1 (ru) Способы секвенирования белков de novo
CN106093244A (zh) 一种羊特征性多肽及其应用
DE60135504D1 (de) Isotop-kodierte ionisierung-förderende reagenzien zur hochdurchsatz protein identifikation und quantifikation mit massenspectrometrie
ATE506616T1 (de) Screening-verfahren
CN106053697B (zh) 一种牛源性特征性多肽及其应用
JP5999699B2 (ja) タンパク質定量方法
CA2507864A1 (en) Methods of quantitation and identification of peptides and proteins
UA112515C2 (uk) Спосіб виявлення присутності двох або більше білків, що становлять інтерес, в зразках рослинного походження
Wu et al. Localizing Isomerized Residue Sites in Peptides with Tandem Mass Spectrometry
Kuyama et al. Enriching C-terminal peptide from endopeptidase ArgC digest for protein C-terminal analysis
WO2006002841A3 (en) Analysis method
KR102406008B1 (ko) 전자전달해리(etd) 질량분석을 이용한 단백질의 정량분석법
Mora et al. Methodologies for peptidomics: Identification and quantification

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties