ATE461453T1 - Nukleinsäuresequenz und protein, das eine rolle bei der zellulären alterung spielt - Google Patents

Nukleinsäuresequenz und protein, das eine rolle bei der zellulären alterung spielt

Info

Publication number
ATE461453T1
ATE461453T1 AT01948093T AT01948093T ATE461453T1 AT E461453 T1 ATE461453 T1 AT E461453T1 AT 01948093 T AT01948093 T AT 01948093T AT 01948093 T AT01948093 T AT 01948093T AT E461453 T1 ATE461453 T1 AT E461453T1
Authority
AT
Austria
Prior art keywords
nucleic acid
role
acid sequence
cellular aging
protein playing
Prior art date
Application number
AT01948093T
Other languages
English (en)
Inventor
Sang-Chul Park
Woong-Yang Park
Jeong-Soo Park
Kyung-A Cho
Deok-In Kim
Original Assignee
Seoul Nat Univ Ind Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from KR10-2000-0053341A external-priority patent/KR100460190B1/ko
Priority claimed from KR10-2000-0053342A external-priority patent/KR100489188B1/ko
Application filed by Seoul Nat Univ Ind Foundation filed Critical Seoul Nat Univ Ind Foundation
Application granted granted Critical
Publication of ATE461453T1 publication Critical patent/ATE461453T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2510/00—Detection of programmed cell death, i.e. apoptosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Genetics & Genomics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
AT01948093T 2000-09-08 2001-07-06 Nukleinsäuresequenz und protein, das eine rolle bei der zellulären alterung spielt ATE461453T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR10-2000-0053341A KR100460190B1 (ko) 2000-09-08 2000-09-08 암피파이신을 이용한 노화 세포의 검출방법, 노화 세포의기능성 회복용 조성물 및 노화 세포의 기능 회복 방법
KR10-2000-0053342A KR100489188B1 (ko) 2000-09-08 2000-09-08 카베올린을 이용한 노화 세포의 검출방법, 세포의 노화유도용 조성물 및 노화 유도 방법
PCT/KR2001/001159 WO2002021140A1 (en) 2000-09-08 2001-07-06 Nucleic acid sequences and proteins involved in cellular senescence

Publications (1)

Publication Number Publication Date
ATE461453T1 true ATE461453T1 (de) 2010-04-15

Family

ID=26638378

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01948093T ATE461453T1 (de) 2000-09-08 2001-07-06 Nukleinsäuresequenz und protein, das eine rolle bei der zellulären alterung spielt

Country Status (8)

Country Link
US (1) US7001769B2 (de)
EP (1) EP1315970B1 (de)
JP (1) JP3771218B2 (de)
CN (1) CN1460181A (de)
AT (1) ATE461453T1 (de)
AU (1) AU2001269575A1 (de)
DE (1) DE60141588D1 (de)
WO (1) WO2002021140A1 (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100489188B1 (ko) * 2000-09-08 2005-05-17 재단법인서울대학교산학협력재단 카베올린을 이용한 노화 세포의 검출방법, 세포의 노화유도용 조성물 및 노화 유도 방법
KR100460190B1 (ko) * 2000-09-08 2004-12-04 재단법인서울대학교산학협력재단 암피파이신을 이용한 노화 세포의 검출방법, 노화 세포의기능성 회복용 조성물 및 노화 세포의 기능 회복 방법
US6982253B2 (en) 2002-06-05 2006-01-03 Supergen, Inc. Liquid formulation of decitabine and use of the same
KR100614523B1 (ko) * 2003-07-24 2006-08-22 재단법인서울대학교산학협력재단 노화세포의 생물학적 기능 회복 방법
US7250416B2 (en) 2005-03-11 2007-07-31 Supergen, Inc. Azacytosine analogs and derivatives
US7700567B2 (en) 2005-09-29 2010-04-20 Supergen, Inc. Oligonucleotide analogues incorporating 5-aza-cytosine therein
JP2009531438A (ja) * 2006-03-24 2009-09-03 ジェンシア コーポレイション 合成脂質ラフトおよび使用方法
KR100896998B1 (ko) * 2007-05-15 2009-05-14 재단법인서울대학교산학협력재단 Ｎ―〔2―（사이클로헥실옥실）―4―니트로페닐〕―메탄술폰아미드를 포함하는 세포 노화억제 조성물
EP3431142B1 (de) 2011-08-30 2020-06-17 Astex Pharmaceuticals, Inc. Decitabinderivatformulierungen
CN105765083B (zh) * 2013-09-27 2021-05-04 加利福尼亚大学董事会 基于表观遗传学标记物来估计组织和细胞类型的年龄的方法
AU2016287585B2 (en) 2015-07-02 2020-12-17 Otsuka Pharmaceutical Co., Ltd. Lyophilized pharmaceutical compositions
RU2020108580A (ru) 2017-08-03 2021-09-03 Оцука Фармасьютикал Ко., Лтд. Лекарственное соединение и способы его очистки
CN107496432A (zh) * 2017-08-08 2017-12-22 拜尔思路生物科技（北京）有限公司 一种通过抑制小窝蛋白延缓细胞衰老的方法
CN111366736A (zh) * 2020-03-31 2020-07-03 中国科学院昆明动物研究所 指征健康衰老关键通路的血清蛋白质标志物及应用
CN112725437B (zh) * 2021-02-02 2022-12-06 暨南大学 节律基因蛋白表达和rna甲基化修饰在制备衰老检测试剂盒中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4196265A (en) 1977-06-15 1980-04-01 The Wistar Institute Method of producing antibodies
US20020197602A1 (en) 1998-04-15 2002-12-26 Glenna C. Burmer Nucleic acid sequences and proteins associated with aging
AU7987800A (en) 1999-09-29 2001-04-30 Lifespan Biosciences, Inc. Anti-aging nucleic acid and protein targets

Also Published As

Publication number Publication date
AU2001269575A1 (en) 2002-03-22
CN1460181A (zh) 2003-12-03
WO2002021140A1 (en) 2002-03-14
JP2004508031A (ja) 2004-03-18
EP1315970B1 (de) 2010-03-17
US7001769B2 (en) 2006-02-21
EP1315970A1 (de) 2003-06-04
JP3771218B2 (ja) 2006-04-26
US20050261265A1 (en) 2005-11-24
DE60141588D1 (de) 2010-04-29

Similar Documents

Publication Publication Date Title
ATE461453T1 (de) Nukleinsäuresequenz und protein, das eine rolle bei der zellulären alterung spielt
DK1268431T3 (da) 3-Cyanoquinoliner, 3-cyano-1,6-naphthyridiner og 3-cyano-1,7-naphthyridiner som proteinkinaseinhibitorer
DE60329983D1 (de) Wachsestersynthase-dna-sequenz, protein und verwendungen davon
DE60233955D1 (de) Spezifische bindungsmittel von human angiopoietin-2
TR200100056T2 (tr) Nörotrofik faktörler
NO20030110L (no) Polymer-modifiserte bioaktive syntetiske kjemokiner, fremgangsmåter for deres fremstilling og anvendelse
ATE330017T1 (de) Kallikrein gen
ATA19742000A (de) Allergie-testkammer
DE60105696D1 (de) Eisenhaltige Proteinzusammensetzung
DE60139544D1 (de) Veränderte, fluoreszierende proteine
NO20013853L (no) Heteroarylamidiner, metylamidiner og guanidiner som proteaseinhibitorer
WO2003016551A3 (en) Novel salicylic acid-binding protein encoding nucleic acid, sabp2, and methods of use thereof
DK1075523T3 (da) Strukturelle proteiner hos fiskepankreassygdomsvirus og anvendelser deraf
DK1339853T3 (da) Isolerede luciferaser og deres anvendelse
ITRM20000494A0 (it) Varianti di allergeni ns-ltps, loro usi e composizioni che le comprendono.
FI20030851A7 (fi) CARD-geenistä ylävirtaan olevia sekvenssejä, niitä sisältäviä vektoreita ja niiden käyttöjä
EP1383907A4 (de) Isolierte menschliche protease-proteine, menschliche protease-proteine codierende nukleinsäuremoleküle sowie verwendungen davon
DE60228227D1 (de) Regenerieren von bei der herstellung von bisphenolen verwendeten katalysatoren
NO20030821D0 (no) Gener og proteiner, og deres anvendelse
EP1433849A4 (de) Neues polypeptid, seine dna und verwendung davon
DE60239055D1 (de) Verbesserungen in der lederherstellung
EP1447411A4 (de) Neues protein, dessen dna und dessen verwendung
EP1395674A4 (de) Isolierte menschliche proteaseproteine, menschliche proteaseproteine codierende nukleinsäuremoleküle und verwendungen davon
EP1379678A4 (de) Isolierte menschliche proteaseproteine, menschliche proteaseproteine codierende nukleinsäuremoleküle und verwendungen davon
AU8557801A (en) Modified proteins, isolated novel peptides, and uses thereof

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties