ATE46441T1 - Ophthalmische loesungen. - Google Patents

Ophthalmische loesungen.

Info

Publication number
ATE46441T1
ATE46441T1 AT82305092T AT82305092T ATE46441T1 AT E46441 T1 ATE46441 T1 AT E46441T1 AT 82305092 T AT82305092 T AT 82305092T AT 82305092 T AT82305092 T AT 82305092T AT E46441 T1 ATE46441 T1 AT E46441T1
Authority
AT
Austria
Prior art keywords
ammonium chloride
solutions
butenyl
hydroxyethyl
tris
Prior art date
Application number
AT82305092T
Other languages
English (en)
Inventor
Raymond Lloyd Stark
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Application granted granted Critical
Publication of ATE46441T1 publication Critical patent/ATE46441T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L12/00—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor
    • A61L12/08—Methods or apparatus for disinfecting or sterilising contact lenses; Accessories therefor using chemical substances
    • A61L12/14—Organic compounds not covered by groups A61L12/10 or A61L12/12
    • A61L12/143—Quaternary ammonium compounds
    • A61L12/145—Polymeric quaternary ammonium compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/785—Polymers containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Apparatus For Disinfection Or Sterilisation (AREA)
  • Eyeglasses (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
AT82305092T 1981-09-28 1982-09-27 Ophthalmische loesungen. ATE46441T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/306,317 US4407791A (en) 1981-09-28 1981-09-28 Ophthalmic solutions
EP82305092A EP0076136B1 (de) 1981-09-28 1982-09-27 Ophthalmische Lösungen

Publications (1)

Publication Number Publication Date
ATE46441T1 true ATE46441T1 (de) 1989-10-15

Family

ID=23184759

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82305092T ATE46441T1 (de) 1981-09-28 1982-09-27 Ophthalmische loesungen.

Country Status (16)

Country Link
US (1) US4407791A (de)
EP (1) EP0076136B1 (de)
JP (1) JPS58501515A (de)
AT (1) ATE46441T1 (de)
AU (1) AU557817B2 (de)
CA (1) CA1194421A (de)
DE (1) DE3279945D1 (de)
DK (1) DK163265C (de)
FI (1) FI78789C (de)
GR (1) GR77661B (de)
IE (1) IE55742B1 (de)
MX (1) MX160782A (de)
NZ (1) NZ201967A (de)
PH (1) PH19376A (de)
WO (1) WO1983001003A1 (de)
ZA (1) ZA826966B (de)

Families Citing this family (128)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1259542A (en) * 1984-09-28 1989-09-19 Francis X. Smith Disinfecting and preserving solutions for contact lenses and methods of use
US4599195A (en) * 1984-12-28 1986-07-08 Alcon Laboratories, Inc. Solution and method for removing protein, lipid, and calcium deposits from contact lenses
US4609493A (en) * 1984-12-28 1986-09-02 Alcon Laboratories, Inc. Solution and method for removing inorganic and organic deposits from contact lenses
US5672575A (en) * 1984-12-28 1997-09-30 Alcon Laboratories, Inc. Use of pluronic surfactant to enhance the cleaning effect of pancreatin on contact lenses
US5318717A (en) * 1984-12-28 1994-06-07 Alcon Laboratories, Inc. Use of nonionic surfactant to enhance the cleaning effect of pancreatin on contact lenses
PH21406A (en) * 1985-04-19 1987-10-15 Ciba Geigy Ag Ophthalmic solution and methods for improving the comfort and safety of contact lenses
US4748189A (en) * 1985-04-19 1988-05-31 Ciba-Geigy Corporation Ophthalmic solutions and methods for improving the comfort and safety of contact lenses
EP0339120A1 (de) * 1988-04-29 1989-11-02 Sterling Drug Inc. Isotrope Waschmittel
US4904698A (en) * 1988-02-11 1990-02-27 Ocusoft Inc. Eyelid cleansing composition
US5165918A (en) * 1988-06-28 1992-11-24 Ciba-Geigy Corporation Antimicrobial ophthalmic solutions containing dodecyl-dimethyl-(2 phenoxyethyl)-ammonium bromide and methods of using the same
US5037647A (en) * 1988-09-15 1991-08-06 Alcon Laboratories, Inc. Aqueous antimicrobial opthalmic solutions comprised of quaternary ammonium compound, citric acid, citrate and sodium chloride
US5300296A (en) * 1989-11-06 1994-04-05 Frank J. Holly Antimicrobial agent for opthalmic formulations
JP3188448B2 (ja) 1989-12-15 2001-07-16 ノバルティス アクチエンゲゼル シャフト ｐＨを調節されたタンパク質除去洗浄剤
US5124154A (en) * 1990-06-12 1992-06-23 Insite Vision Incorporated Aminosteroids for ophthalmic use
US5512597A (en) * 1991-11-08 1996-04-30 Alcon Laboratories, Inc. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobials
US6051611A (en) * 1991-11-08 2000-04-18 Alcon Laboratories, Inc. Polymeric quaternary ammonium compounds and their use as ophthalmic antimicrobias
US5547663A (en) * 1991-11-08 1996-08-20 Alcon Laboratories, Inc. Absolute molecular weight polymers and methods for their use
US5256420A (en) * 1991-12-23 1993-10-26 Ciba-Geigy Corporation Method of imparting antimicrobial acitivity to an ophthalmic composition
US5252246A (en) * 1992-01-10 1993-10-12 Allergan, Inc. Nonirritating nonionic surfactant compositions
US5290572A (en) * 1992-08-06 1994-03-01 Deo Corporation Opthalmic composition for treating dry eye
US5830508A (en) * 1992-08-06 1998-11-03 Deo Corporation Composition for treating dry eye
US5356555A (en) * 1992-09-14 1994-10-18 Allergan, Inc. Non-oxidative method and composition for simultaneously cleaning and disinfecting contact lenses using a protease with a disinfectant
EP0674532B1 (de) * 1992-12-17 2003-05-28 Advanced Medical Optics, Inc. Oxidationsmittel und polyvinylpyrrolidon enthaltende desinfektionslösung für kontaktlinsen
US5340572A (en) * 1993-02-08 1994-08-23 Insite Vision Incorporated Alkaline ophthalmic suspensions
WO1994025426A1 (en) * 1993-04-28 1994-11-10 Alcon Laboratories, Inc. Diamines as antimicrobial agents and use thereof in ophthalmic composition
US5370744B1 (en) * 1993-08-27 1999-11-09 Alcon Lab Inc Process for cleaning and disinfecting contact lenses
US5631005A (en) * 1994-09-21 1997-05-20 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5573726A (en) * 1993-09-22 1996-11-12 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5393491A (en) * 1993-09-22 1995-02-28 Alcon Laboratories, Inc. Use of amidoamines in ophthalmic compositions
US5415837A (en) * 1993-10-25 1995-05-16 Alcon Laboratories, Inc. Use of diamines to disinfect and clean contact lenses
US5532224A (en) * 1993-12-22 1996-07-02 Alcon Laboratories, Inc. Contact lens cleaning composition containing polyalklene oxide modified siloxanes
US5549894A (en) * 1994-01-18 1996-08-27 Allergan, Inc. Disinfecton formulations and methods using D-enantiomeric anti-microbial peptides
AU2553995A (en) * 1994-06-15 1996-01-05 Alcon Laboratories, Inc. Improved method for storing contact lenses
AU3070395A (en) * 1994-07-22 1996-02-22 Alcon Laboratories, Inc. Use of low molecular weight amino acids in ophthalmic compositions
US5536494A (en) * 1994-10-04 1996-07-16 Alcon Laboratories, Inc. Polyethylene oxide-containing quaternary ammunium polymers and pharmaceutical compositions containing an antimicrobial amount of same
US5603929A (en) * 1994-11-16 1997-02-18 Alcon Laboratories, Inc. Preserved ophthalmic drug compositions containing polymeric quaternary ammonium compounds
US5604190A (en) * 1995-06-07 1997-02-18 Alcon Laboratories, Inc. Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5723421A (en) * 1995-06-07 1998-03-03 Alcon Laboratories, Inc. Stable liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US6184189B1 (en) 1995-06-07 2001-02-06 Alcon Laboratories, Inc. Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5576278A (en) * 1995-06-07 1996-11-19 Alcon Laboratories, Inc. Stable liquid enzyme compositions and methods of use
US5868868A (en) * 1995-06-19 1999-02-09 Alcon Laboratories, Inc. Peg-modified proteases and methods of use in contact lens cleaning
US5672213A (en) * 1995-08-18 1997-09-30 Alcon Laboratories, Inc. Liquid enzyme compositions containing aromatic acid derivatives
US5605661A (en) * 1995-08-18 1997-02-25 Alcon Laboratories, Inc. Methods of using liquid enzyme compositions containing mixed polyols
US5718895A (en) * 1995-11-16 1998-02-17 Alcon Laboratories, Inc. Enzymes with low isoelectric points for use in contact lens cleaning
JP2000505486A (ja) * 1996-02-14 2000-05-09 アルコン ラボラトリーズ，インコーポレイテッド ポリマー第４級アンモニウム化合物と、眼科用抗微生物剤としてのその使用
US6358897B1 (en) 1996-06-07 2002-03-19 Alcon Laboratories, Inc. Alkyl trypsin compositions and methods of use in contact lens cleaning and disinfecting systems
US6034129A (en) * 1996-06-24 2000-03-07 Geltex Pharmaceuticals, Inc. Ionic polymers as anti-infective agents
EP0877600B1 (de) * 1996-08-09 2003-10-22 Alcon Manufacturing Ltd. Konservierungssysteme fur cyclodextrine enthaltende arzneimittel
BR9711406A (pt) * 1996-09-20 1999-08-17 Bausch & Lomb Sistema e m-todo para reumidifica-Æo de lentes de contato e alivio da secura dos olhos
ATE326983T1 (de) 1996-12-13 2006-06-15 Alcon Lab Inc Aminoalkohole enthaltende ophthalmische zusammensetzungen
US6228323B1 (en) 1996-12-13 2001-05-08 Alcon Laboratories, Inc. Multi-purpose compositions containing an alkyl-trypsin and methods of use in contact lens cleaning and disinfecting
US6214596B1 (en) 1996-12-18 2001-04-10 Alcon Laboratories, Inc. Liquid enzyme compositions and methods of use in contact lens cleaning and disinfecting systems
US5788852A (en) * 1997-04-18 1998-08-04 Mescon; Howard Michael Process for preventing accumulation of contaminants in dental suction systems
AU725552B2 (en) 1997-07-29 2000-10-12 Alcon Laboratories, Inc. Conditioning solutions for hard contact lens care
US6007803A (en) * 1997-09-19 1999-12-28 Geltex Pharmaceuticals, Inc. Ionic polymers as toxin binding agents
US6290947B1 (en) 1997-09-19 2001-09-18 Geltex Pharmaceuticals, Inc. Ionic polymers as toxin-binding agents
US20030129083A1 (en) * 1997-11-26 2003-07-10 Advanced Medical Optics, Inc. Multi purpose contact lens care compositions including propylene glycol or glycerin
ZA9811445B (en) 1997-12-19 1999-08-16 Alcon Lab Inc Aminobiguanides and the use thereof to disinfect contact lenses and preserve pharmaceutical compositions.
JP3883739B2 (ja) * 1998-05-22 2007-02-21 株式会社メニコン コンタクトレンズ用殺菌液
US20030086986A1 (en) 1998-08-06 2003-05-08 Bruijn Chris De Ophthalmic, pharmaceutical and other healthcare preparations with naturally occurring plant compounds, extracts and derivatives
EP1050304A1 (de) * 1998-11-16 2000-11-08 Rohto Pharmaceutical Co., Ltd. Flüssige augenarznei-zusammensetzungen
US6482402B1 (en) 1999-05-13 2002-11-19 Geltex Pharmaceuticals, Inc. Antimicrobial compositions and methods
CA2395866C (en) 2000-01-25 2009-10-13 Alcon, Inc. Ophthalmic anti-allergy compositions suitable for use with contact lenses
US8858961B2 (en) 2000-07-14 2014-10-14 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US20050026924A1 (en) * 2000-07-14 2005-02-03 Allergan, Inc. Compositions containing alpha-2-adrenergic agonist components
US7977376B2 (en) 2001-06-27 2011-07-12 Novartis Ag Olopatadine formulations for topical nasal administration
TWI231759B (en) * 2001-06-27 2005-05-01 Alcon Inc Olopatadine formulations for topical administration
US7402318B2 (en) * 2001-11-14 2008-07-22 Novartis Ag Medical devices having antimicrobial coatings thereon
WO2004069157A2 (en) * 2003-01-17 2004-08-19 Ophthalmic Research Associates, Inc. Combinational use of long-acting and short-acting anti-histamines for ocular allergies
US20050042712A1 (en) * 2003-08-22 2005-02-24 Advanced Medical Optics, Inc. Methods, compositions and instruments to predict antimicrobial or preservative activity
US20050239745A1 (en) * 2004-03-03 2005-10-27 Ophthalmic Research Associates, Inc. Novel topical ophthalmic formulations
US20060270592A1 (en) * 2004-03-19 2006-11-30 Ophthalmic Research Associates, Inc. Use of neurotransmitters and neuropeptides for the treatment of dry eye diseases and related conditions
CA2505836C (en) * 2004-05-06 2013-08-27 Alcon Inc. Topical brimonidine tartrate formulations that lack chlorine dioxide
JP5108234B2 (ja) * 2005-02-07 2012-12-26 日本特殊陶業株式会社 マイクロヒータ及びセンサ
JP5154231B2 (ja) 2005-02-14 2013-02-27 ジョンソン・アンド・ジョンソン・ビジョン・ケア・インコーポレイテッド 快適な眼科用具およびその製造法
US20070254841A1 (en) * 2006-01-25 2007-11-01 Ophthalmic Research Associates, Inc. Formulations and methods for treating dry eye
US20100130580A1 (en) * 2006-01-25 2010-05-27 Aciex Therapeutics, Inc. Formulations and Methods for Treating Dry Eye
DE102006004111B4 (de) * 2006-01-28 2015-11-19 Wöhlk-Contact-Linsen GmbH Kontaktlinsenmaterial
US9052529B2 (en) 2006-02-10 2015-06-09 Johnson & Johnson Vision Care, Inc. Comfortable ophthalmic device and methods of its production
US20090136598A1 (en) * 2006-04-26 2009-05-28 Aciex, Inc. Compositions for the Treatment and Prevention of Eyelid Swelling
WO2007127333A2 (en) * 2006-04-26 2007-11-08 Aciex, Inc. Compositions for the treatment and prevention of eyelid swelling
JP2010520210A (ja) * 2007-02-28 2010-06-10 アーシエックス セラピューティックス， インコーポレイテッド マイボーム腺分泌を正常化するための方法および組成物
TW200904485A (en) * 2007-05-18 2009-02-01 Alcon Res Ltd Phospholipid compositions for contact lens care and preservation of pharmaceutical compositions
MX2009012645A (es) * 2007-05-24 2010-03-08 Aciex Therapeutics Inc Formulaciones y metodos para tratar el ojo seco.
TWI544927B (zh) 2008-03-17 2016-08-11 愛爾康研究有限公司 具有低濃度的表面活性劑以促進治療劑之生物可利用性的藥學組成物
BRPI0909738A2 (pt) 2008-03-17 2015-10-06 Alcon Res Ltd composições farmacêuticas aquosas contendo complexos de boratopoliol
TWI454289B (zh) * 2008-04-03 2014-10-01 Alcon Res Ltd 使用順式二醇的聚合物於抑制陽離子殺生物劑被吸收進入水凝膠生物材質中之用途
WO2009142950A1 (en) * 2008-05-19 2009-11-26 Alcon Research, Ltd. Pharmaceutical compositions having carboxyvinyl polymer and povidone polymer
US20090298956A1 (en) * 2008-05-28 2009-12-03 Chowhan Masood A Self-preserved emulsions
US8093352B2 (en) * 2008-08-05 2012-01-10 Alcon Research, Ltd. Polyalkylene oxide polyquaternary ammonium biocides
TW201010727A (en) * 2008-09-03 2010-03-16 Alcon Res Ltd Pharmaceutical composition having relatively low ionic strength
TW201023912A (en) 2008-12-05 2010-07-01 Alcon Res Ltd Pharmaceutical suspension
CN102264344A (zh) * 2008-12-22 2011-11-30 爱尔康研究有限公司 递送有效浓度的活性剂至眼睛后段的局部眼用溶液组合物
US8431751B1 (en) 2008-12-24 2013-04-30 Alcon Research, Ltd. Polymeric quaternary ammonium compounds with vicinal hydroxy groups
US20100197702A1 (en) * 2009-02-04 2010-08-05 Hellberg Mark R Ophthalmic composition with nitric oxide donor compound and method of forming and using same
AU2010221438C1 (en) * 2009-03-03 2015-01-29 Alcon Research, Ltd. Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye
US8912236B2 (en) * 2009-03-03 2014-12-16 Alcon Research, Ltd. Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye
EP2408302A4 (de) * 2009-03-17 2012-08-15 Aciex Therapeutics Inc Ophthalmische formulierungen aus ketotifen und verfahren zu ihrer verwendung
US8569273B2 (en) 2009-03-17 2013-10-29 Aciex Therapeutics, Inc. Ophthalmic formulations of cetirizine and methods of use
EP2408453B1 (de) 2009-03-17 2022-01-05 Nicox Ophthalmics, Inc. Ophthalmische formulierungen aus cetirizin und verfahren zu ihrer verwendung
TW201038295A (en) * 2009-04-17 2010-11-01 Alcon Res Ltd Aqueous ophthalmic compositions containing anionic therapeutic agents
US8349303B1 (en) 2009-04-29 2013-01-08 Bausch & Lomb Incorporated Polymeric quaternium compounds
US20110105450A1 (en) * 2009-06-05 2011-05-05 Aciex Therapeutics, Inc. Ophthalmic formulations of fluticasone and methods of use
TWI489997B (zh) * 2009-06-19 2015-07-01 Alcon Res Ltd 含有硼酸－多元醇錯合物之水性藥學組成物
TWI478730B (zh) 2009-12-03 2015-04-01 Alcon Res Ltd 眼科乳劑
WO2011085385A1 (en) * 2010-01-11 2011-07-14 Gtx, Inc. Methods of treating meibomian gland dysfunction
EP2359690A1 (de) 2010-02-23 2011-08-24 East Coast Pharmaceutical Research LLC Vervielfachung der Wirksamkeit von Antiinfektiosa mittels einer Zusammensetzung, die gleichzeitig ein Dispergiermittel und ein Metallaktivierungsmittel umfasst
EP2654771A1 (de) 2010-12-21 2013-10-30 Recopharma Ab Tränenflüssigkeitssubstitute
US20120225918A1 (en) 2011-03-03 2012-09-06 Voom, Llc Compositions and Methods for Non-Surgical Treatment of Ptosis
CN104039307A (zh) 2011-04-22 2014-09-10 爱尔康研究有限公司 具有包含两种不同粘度增强剂的粘度增强体系的眼用组合物
EP3045163A1 (de) 2011-04-22 2016-07-20 Alcon Research, Ltd. Ophthalmische zusammensetzung mit einem viskositätsverstärkungssystem mit zwei unterschiedlichen viskositätsverstärkern
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠（ｏｌｏｐａｔａｄｉｎｅ）眼用組成物
TW201336527A (zh) 2012-02-10 2013-09-16 Alcon Res Ltd 具增強的穩定性之水性藥學組成物
PT3517541T (pt) 2012-05-08 2020-08-28 Nicox Ophthalmics Inc Forma polimórfica de propionato de fluticasona
US8765725B2 (en) 2012-05-08 2014-07-01 Aciex Therapeutics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
US9815865B2 (en) 2013-01-07 2017-11-14 Nicox Ophthalmics, Inc. Preparations of hydrophobic therapeutic agents, methods of manufacture and use thereof
WO2014135984A2 (en) 2013-03-07 2014-09-12 Recopharma Ab Glycosylated mucin-immunoglobulin fusion protein coated device
US10174006B2 (en) 2013-06-06 2019-01-08 Novartis Ag Topical aqueous ophthalmic compositions containing a 1H-indole-1-carboxamide derivative and use thereof for treatment of ophthalmic disease
MY180543A (en) 2013-12-17 2020-12-01 Novartis Ag A silicone hydrogel lens with a crosslinked hydrophilic coating
WO2017053339A1 (en) 2015-09-24 2017-03-30 Matrix Biology Institute High elasticity hyaluronan compositions and methods of use thereof
CA3015494C (en) 2016-03-30 2021-10-26 Ayuvis Research, Inc. Novel compositions and therapeutic methods
TWI884130B (zh) 2018-02-21 2025-05-21 瑞士商愛爾康公司 基於脂質的眼用乳劑
CA3103503A1 (en) 2018-07-02 2020-01-09 Ayuvis Research, Inc. Novel immunodulating small molecules
EP3924345A1 (de) 2019-02-15 2021-12-22 Novartis AG Kristalline formen von 4-(7-hydroxy-2-isopropyl-4-oxo-4h-chinazolin-3-yl)-benzonitril und deren formulierungen
JP6994061B2 (ja) 2019-02-15 2022-01-14 ノバルティス アーゲー ４－（７－ヒドロキシ－２－イソプロピル－４－オキソ－４ｈ－キナゾリン－３－イル）－ベンゾニトリルの製剤
US12459902B2 (en) 2020-08-06 2025-11-04 Bausch + Lomb Ireland Limited Crystalline forms of 4-(7-hydroxy-2-isopropyl-4-oxo-4H-quinazolin-3-yl)-benzonitrile and formulations thereof
WO2022187306A1 (en) 2021-03-03 2022-09-09 Voom, Llc Compositions and methods for treatment of blepharitis
AU2023346366A1 (en) 2022-09-21 2025-03-20 Bausch + Lomb Ireland Limited Crystalline polymorph forms of a trpv1 antagonist and formulations thereof

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USB724600I5 (de) * 1968-04-26
US3639576A (en) * 1968-06-19 1972-02-01 Barnes Hind Pharm Inc Resterilizing contact lens solution
US4005193A (en) * 1974-08-07 1977-01-25 Millmaster Onyx Corporation Microbiocidal polymeric quaternary ammonium compounds
US4026945A (en) * 1974-10-03 1977-05-31 Millmaster Onyx Corporation Anti-microbial quaternary ammonium co-polymers
US3966904A (en) * 1974-10-03 1976-06-29 Millmaster Onyx Corporation Quaternary ammonium co-polymers for controlling the proliferation of bacteria
US3961042A (en) * 1974-10-03 1976-06-01 Millmaster Onyx Corporation Quaternary ammonium co-polymers for controlling the proliferation of bacteria
US4012446A (en) * 1974-10-29 1977-03-15 Millmaster Onyx Corporation Capped polymers
US4027020A (en) * 1974-10-29 1977-05-31 Millmaster Onyx Corporation Randomly terminated capped polymers
US4025945A (en) * 1975-07-25 1977-05-24 Rca Corporation Color function display system
GB2027040B (en) * 1978-04-26 1982-09-29 Smith & Nephew Pharma Polymers of diallylamine quarternary salts sterilizing agents
CA1138341A (en) * 1980-01-23 1982-12-28 Leszek J. Wolfram Waving composition from a reducing agent and cationic polymer

Also Published As

Publication number Publication date
FI831770A0 (fi) 1983-05-19
IE822338L (en) 1983-03-28
PH19376A (en) 1986-04-02
DK163265C (da) 1992-07-06
FI831770L (fi) 1983-05-19
GR77661B (de) 1984-09-25
DK223883A (da) 1983-05-19
DE3279945D1 (en) 1989-10-26
US4407791A (en) 1983-10-04
FI78789B (fi) 1989-05-31
FI78789C (fi) 1989-09-11
DK223883D0 (da) 1983-05-19
AU557817B2 (en) 1987-01-08
EP0076136A3 (en) 1985-04-17
DK163265B (da) 1992-02-10
ZA826966B (en) 1983-07-27
JPS58501515A (ja) 1983-09-08
CA1194421A (en) 1985-10-01
MX160782A (es) 1990-05-16
EP0076136A2 (de) 1983-04-06
EP0076136B1 (de) 1989-09-20
AU9050382A (en) 1983-04-08
IE55742B1 (en) 1991-01-02
WO1983001003A1 (en) 1983-03-31
NZ201967A (en) 1985-03-20
JPH0254804B2 (de) 1990-11-22

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