ATE464567T1 - Diagnostische und therapeutische verwendung von f-box-proteinen bei morbus alzheimer und verwandten neurodegenerativen erkrankungen - Google Patents

Diagnostische und therapeutische verwendung von f-box-proteinen bei morbus alzheimer und verwandten neurodegenerativen erkrankungen

Info

Publication number: ATE464567T1
Authority: AT; Austria
Prior art keywords: disease; alzheimer; neurodegenerative diseases; diagnostic; box
Prior art date: 2001-09-07

Application number

AT02797965T

Other languages

English (en)

Inventor

Der Kammer Heinz Von

Johannes Pohlner

Rainer Hipfel

Original Assignee

Takeda Pharmaceutical

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-07

Filing date

2002-09-07

Publication date

2010-04-15

2002-09-07 Application filed by Takeda Pharmaceutical filed Critical Takeda Pharmaceutical

2010-04-15 Application granted granted Critical

2010-04-15 Publication of ATE464567T1 publication Critical patent/ATE464567T1/de

Links

208000024827 Alzheimer disease Diseases 0.000 title abstract 5
108010066805 F-Box Proteins Proteins 0.000 title abstract 3
102000018700 F-Box Proteins Human genes 0.000 title abstract 3
208000015122 neurodegenerative disease Diseases 0.000 title abstract 3
230000001225 therapeutic effect Effects 0.000 title abstract 2
238000000034 method Methods 0.000 abstract 3
102100027747 F-box/LRR-repeat protein 20 Human genes 0.000 abstract 2
101001026881 Homo sapiens F-box/LRR-repeat protein 2 Proteins 0.000 abstract 2
101000862163 Homo sapiens F-box/LRR-repeat protein 20 Proteins 0.000 abstract 2
108010006444 Leucine-Rich Repeat Proteins Proteins 0.000 abstract 2
108090000623 proteins and genes Proteins 0.000 abstract 2
210000004556 brain Anatomy 0.000 abstract 1
230000004770 neurodegeneration Effects 0.000 abstract 1
230000000069 prophylactic effect Effects 0.000 abstract 1
238000012216 screening Methods 0.000 abstract 1

Classifications

- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
- G01N33/6896—Neurological disorders, e.g. Alzheimer's disease
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/28—Neurological disorders
- G01N2800/2814—Dementia; Cognitive disorders
- G01N2800/2821—Alzheimer

Landscapes

Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Hematology (AREA)
Chemical & Material Sciences (AREA)
Urology & Nephrology (AREA)
Molecular Biology (AREA)
Immunology (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Food Science & Technology (AREA)
Medicinal Chemistry (AREA)
Physics & Mathematics (AREA)
Analytical Chemistry (AREA)
Biochemistry (AREA)
Cell Biology (AREA)
General Physics & Mathematics (AREA)
Pathology (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Investigating Or Analysing Biological Materials (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

AT02797965T 2001-09-07 2002-09-07 Diagnostische und therapeutische verwendung von f-box-proteinen bei morbus alzheimer und verwandten neurodegenerativen erkrankungen ATE464567T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01121442		2001-09-07
PCT/EP2002/010057 WO2003023405A1 (en)	2001-09-07	2002-09-07	Diagnostic and therapeutic use of f-box proteins for alzheimer's disease and related neurodegenerative disorders

Publications (1)

Publication Number	Publication Date
ATE464567T1 true ATE464567T1 (de)	2010-04-15

Family

ID=8178573

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT02797965T ATE464567T1 (de)	2001-09-07	2002-09-07	Diagnostische und therapeutische verwendung von f-box-proteinen bei morbus alzheimer und verwandten neurodegenerativen erkrankungen

Country Status (6)

Country	Link
US (2)	US20040241694A1 (de)
EP (1)	EP1423704B1 (de)
JP (1)	JP2005502368A (de)
AT (1)	ATE464567T1 (de)
DE (1)	DE60235996D1 (de)
WO (1)	WO2003023405A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20060088846A1 (en) *	1998-08-28	2006-04-27	Michele Pagano	Methods to identify compounds useful for the treatment of proliferative and differentiative disorders
EP1489423A1 (de) *	2003-06-20	2004-12-22	Universite Louis Pasteur	Verwendung von mitochondrialen entkoppelnden Proteinen (Uncoupling proteins, UCP) zur Diagnose, Vorbeugung und Behandlung von Erkrankungen mit neuromuskularen Beschwerden
JP4972538B2 (ja) *	2005-02-07	2012-07-11	武田薬品工業株式会社	神経変性疾患の予防・治療剤
JP7368856B2 (ja)	2017-07-25	2023-10-25	トゥルーバインディング，インコーポレイテッド	Ｔｉｍ－３とそのリガンドとの相互作用の遮断によるがん治療
KR102279919B1 (ko) *	2018-11-09	2021-07-21	순천향대학교 산학협력단	신경계 퇴행성 질환 치료 물질의 스크리닝 방법
CN120058944A (zh)	2019-01-30	2025-05-30	真和制药有限公司	抗gal3抗体及其用途
CN110261617B (zh) *	2019-05-14	2022-07-01	深圳市人民医院	脑出血外周血标志物及其应用
JP2023528797A (ja)	2020-05-26	2023-07-06	トゥルーバインディング，インコーポレイテッド	ガレクチン－３を遮断することにより炎症性疾患を処置する方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6426205B1 (en) *	1997-10-24	2002-07-30	Mount Sinai Hospital Corporation	Methods and compositions for modulating ubiquitin dependent proteolysis
US6730778B2 (en) *	1997-12-19	2004-05-04	Pharmacia And Upjohn Company	Human sel-10 polypeptides and polynucleotides that encode them
US5976849A (en)	1998-02-05	1999-11-02	Zeneca Limited	Human E3 ubiquitin protein ligase
WO2000012679A1 (en) *	1998-08-28	2000-03-09	New York University	Novel ubiquitin ligases as therapeutic targets
US6740495B1 (en)	2000-04-03	2004-05-25	Rigel Pharmaceuticals, Inc.	Ubiquitin ligase assay
AU2002246808A1 (en) *	2000-12-19	2002-08-06	Curagen Corporation	Human nucleic acids and polypeptides and methods of use thereof
US20040018970A1 (en) *	2000-12-19	2004-01-29	Shimkets Richard A.	Novel nucleic acids and polypeptides and methods of use thereof

2002
- 2002-09-07 US US10/488,776 patent/US20040241694A1/en not_active Abandoned
- 2002-09-07 DE DE60235996T patent/DE60235996D1/de not_active Expired - Lifetime
- 2002-09-07 WO PCT/EP2002/010057 patent/WO2003023405A1/en not_active Ceased
- 2002-09-07 JP JP2003527425A patent/JP2005502368A/ja active Pending
- 2002-09-07 AT AT02797965T patent/ATE464567T1/de not_active IP Right Cessation
- 2002-09-07 EP EP02797965A patent/EP1423704B1/de not_active Expired - Lifetime
2007
- 2007-02-07 US US11/703,215 patent/US20070199080A1/en not_active Abandoned

Also Published As

Publication number	Publication date
JP2005502368A (ja)	2005-01-27
US20040241694A1 (en)	2004-12-02
DE60235996D1 (de)	2010-05-27
WO2003023405A1 (en)	2003-03-20
EP1423704B1 (de)	2010-04-14
EP1423704A1 (de)	2004-06-02
US20070199080A1 (en)	2007-08-23

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Legal Events

Date	Code	Title	Description
2010-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties