ATE465171T1 - Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren - Google Patents

Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren

Info

Publication number
ATE465171T1
ATE465171T1 AT03743008T AT03743008T ATE465171T1 AT E465171 T1 ATE465171 T1 AT E465171T1 AT 03743008 T AT03743008 T AT 03743008T AT 03743008 T AT03743008 T AT 03743008T AT E465171 T1 ATE465171 T1 AT E465171T1
Authority
AT
Austria
Prior art keywords
modulate
chemokines
peptides
chemokine
biological activity
Prior art date
Application number
AT03743008T
Other languages
English (en)
Inventor
Amnon Peled
Orly Eizenberg
Dalit Vaizel-Ohayon
Original Assignee
Biokine Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biokine Therapeutics Ltd filed Critical Biokine Therapeutics Ltd
Application granted granted Critical
Publication of ATE465171T1 publication Critical patent/ATE465171T1/de

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G11/00—Chutes
    • B65G11/02—Chutes of straight form
    • B65G11/023—Chutes of straight form for articles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G11/00—Chutes
    • B65G11/16—Interior surfaces; Linings
    • B65G11/163—Interior surfaces; Linings for articles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Transplantation (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
AT03743008T 2002-02-28 2003-02-27 Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren ATE465171T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US35999502P 2002-02-28 2002-02-28
PCT/IL2003/000155 WO2003072599A2 (en) 2002-02-28 2003-02-27 Novel chemokine binding peptides capable of modulating the biological activity of chemokines

Publications (1)

Publication Number Publication Date
ATE465171T1 true ATE465171T1 (de) 2010-05-15

Family

ID=27766173

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03743008T ATE465171T1 (de) 2002-02-28 2003-02-27 Neue chemokine bindende peptide, die die biologische aktivität dieser chemokine modulieren

Country Status (6)

Country Link
US (5) US20030221931A1 (de)
EP (2) EP1519945B1 (de)
AT (1) ATE465171T1 (de)
AU (1) AU2003209636A1 (de)
DE (1) DE60332239D1 (de)
WO (1) WO2003072599A2 (de)

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* Cited by examiner, † Cited by third party
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US20030221931A1 (en) 2002-02-28 2003-12-04 Steve Marsh Sliding device
ATE474589T1 (de) * 2003-10-29 2010-08-15 Univ Ramot Angiogene peptide und ihre verwendungen
US20070083333A1 (en) * 2003-11-17 2007-04-12 Vitiello Maria A Modeling of systemic inflammatory response to infection
CA2575969A1 (en) * 2004-08-05 2006-02-09 L-3 Communications Security And Detection Systems, Inc. Increased throughput inspection station
WO2006052840A2 (en) * 2004-11-04 2006-05-18 University Of Virginia Patent Foundation Bone tropic peptides
DE102006006208B4 (de) * 2006-02-09 2010-11-11 Smiths Heimann Gmbh Kontrollstation zur Überprüfung von Handgepäck und anderen von Personen mitgeführten Gegenständen
US20090324596A1 (en) 2008-06-30 2009-12-31 The Trustees Of Princeton University Methods of identifying and treating poor-prognosis cancers
US10745701B2 (en) 2007-06-28 2020-08-18 The Trustees Of Princeton University Methods of identifying and treating poor-prognosis cancers
US9116513B2 (en) 2008-03-28 2015-08-25 Securitypoint Holdings, Inc. Methods and systems for efficient security screening
US9516460B2 (en) 2008-03-28 2016-12-06 Securitypoint Holdings Llc Systems and methods for security checkpoint condition information and sharing
TWI431014B (zh) * 2008-10-29 2014-03-21 中央研究院 腫瘤標靶胜肽及其於檢測及治療癌症之用途
ES2462517T3 (es) 2009-06-14 2014-05-23 Biokine Therapeutics Ltd. Terapia con péptidos para aumentar los niveles de plaquetas
EP2443137B1 (de) 2009-06-15 2015-05-20 Biokine Therapeutics Ltd. Neue chemokin-bindende peptide, die die fähigkeit, den fortschritt von autoimmunität, entzündung und krebs aufweisen
EP2385057A1 (de) * 2010-05-05 2011-11-09 Centre National de la Recherche Scientifique Peptidderivate zur Biofunktionalisierung von Siliciumsubstraten und deren Anwendungen
CN102174080B (zh) * 2010-09-19 2014-07-09 复旦大学 具有脑靶向递药特性的多肽及其制备方法
EP2632939A4 (de) 2010-10-25 2014-05-14 Academia Sinica Taiwan Auf krebs abgezielte peptide und ihre verwendung in der krebsbehandlung und -diagnose
KR20200016407A (ko) 2011-05-16 2020-02-14 젠자임 코포레이션 Ｃｘｃｒ４ 길항제의 용도
WO2013160895A1 (en) 2012-04-24 2013-10-31 Biokine Therapeutics Ltd. Peptides and use thereof in the treatment of large cell lung cancer
FR3022142B1 (fr) 2014-06-16 2019-07-12 Universite Paul Sabatier - Toulouse Iii Inhibition de la chimiokine ccl7 ou de son recepteur ccr3 pour le traitement et le diagnostic du cancer de la prostate
CN107921087A (zh) 2015-07-16 2018-04-17 百欧肯治疗有限公司 治疗癌症的组合物及方法
WO2017103931A1 (en) 2015-12-17 2017-06-22 Biokine Therapeutics Ltd. Small molecules against cancer
KR102828755B1 (ko) 2015-12-17 2025-07-03 바이오카인 테라퓨틱스 리미티드 케모카인 활성 및/또는 암세포 성장 억제용 저분자
BR112018016924A2 (pt) 2016-02-23 2019-01-02 Biolinerx Ltd método de seleção de regime de tratamento para indivíduo que tem leucemia mieloide aguda (lma), método de maximização de resposta ao tratamento de leucemia mieloide aguda (lma), método de tratamento de lma, antagonista de cxcr4 e agente quimioterápico no tratamento de lma
WO2018047852A1 (en) * 2016-09-07 2018-03-15 Kyoto University Peptides and peptide conjugates for treating mental disorders
EP3864025B1 (de) 2018-10-12 2024-05-08 Theradaptive, Inc. Polypeptide mit einer beta-tricalciumphosphatbindenden sequenz und deren verwendungen
CA3090315C (en) 2019-05-15 2023-09-19 Biokine Therapeutics Ltd. 8-phenoxy-quinolinone derivatives for treating cancer, inhibiting chemokine activity and/or inducing cell death
WO2021194604A2 (en) * 2020-03-06 2021-09-30 Theradaptive, Inc. Therapeutic compositions comprising graft materials and beta-tcp binding peptides and uses thereof
BR112022020809A2 (pt) 2020-04-15 2023-02-23 Theradaptive Inc Composições e métodos para entrega terapêutica direcionada ao osso
KR102736939B1 (ko) * 2021-09-30 2024-12-03 (주)케어젠 항염증 활성을 갖는 펩타이드 및 이의 용도
GB202209520D0 (en) 2022-06-29 2022-08-10 Univ Oxford Innovation Ltd Peptides

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US20030221931A1 (en) 2002-02-28 2003-12-04 Steve Marsh Sliding device

Also Published As

Publication number Publication date
WO2003072599A2 (en) 2003-09-04
EP2287175A2 (de) 2011-02-23
AU2003209636A1 (en) 2003-09-09
EP1519945B1 (de) 2010-04-21
US8383769B2 (en) 2013-02-26
WO2003072599A3 (en) 2003-12-18
US8796227B2 (en) 2014-08-05
EP2287175A3 (de) 2012-05-16
US20040171552A1 (en) 2004-09-02
DE60332239D1 (de) 2010-06-02
US20120028913A1 (en) 2012-02-02
US8039440B2 (en) 2011-10-18
US20100173848A1 (en) 2010-07-08
US20030221931A1 (en) 2003-12-04
US7488717B2 (en) 2009-02-10
EP1519945A2 (de) 2005-04-06
US20130130996A1 (en) 2013-05-23
AU2003209636A8 (en) 2003-09-09

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