ATE466082T1 - Das nphs2 gen, welches im corticoresistenten nephrotischen syndrome eine rolle spielt - Google Patents

Das nphs2 gen, welches im corticoresistenten nephrotischen syndrome eine rolle spielt

Info

Publication number: ATE466082T1
Authority: AT; Austria
Prior art keywords: nephrotic syndrome; corticoresistant; plays; role; nphs2 gene
Prior art date: 2000-01-20

Application number

AT01907652T

Other languages

English (en)

Inventor

Corinne Antignac

Nicolas Boute

Original Assignee

Inst Nat Sante Rech Med

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-01-20

Filing date

2001-01-19

Publication date

2010-05-15

2001-01-19 Application filed by Inst Nat Sante Rech Med filed Critical Inst Nat Sante Rech Med

2010-05-15 Application granted granted Critical

2010-05-15 Publication of ATE466082T1 publication Critical patent/ATE466082T1/de

Links

206010029164 Nephrotic syndrome Diseases 0.000 title abstract 2
101000595193 Homo sapiens Podocin Proteins 0.000 title 1
108090000623 proteins and genes Proteins 0.000 abstract 2
OMFXVFTZEKFJBZ-UHFFFAOYSA-N Corticosterone Natural products O=C1CCC2(C)C3C(O)CC(C)(C(CC4)C(=O)CO)C4C3CCC2=C1 OMFXVFTZEKFJBZ-UHFFFAOYSA-N 0.000 abstract 1
101150052769 NPHS2 gene Proteins 0.000 abstract 1
108091028043 Nucleic acid sequence Proteins 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
OMFXVFTZEKFJBZ-HJTSIMOOSA-N corticosterone Chemical compound O=C1CC[C@]2(C)[C@H]3[C@@H](O)C[C@](C)([C@H](CC4)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 OMFXVFTZEKFJBZ-HJTSIMOOSA-N 0.000 abstract 1
102000004169 proteins and genes Human genes 0.000 abstract 1
230000001225 therapeutic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Cell Biology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Immunology (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Urology & Nephrology (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Veterinary Medicine (AREA)
Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Paper (AREA)

AT01907652T 2000-01-20 2001-01-19 Das nphs2 gen, welches im corticoresistenten nephrotischen syndrome eine rolle spielt ATE466082T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
FR0000709A FR2804127B1 (fr)	2000-01-20	2000-01-20	Gene srn1 implique dans le syndrome nephrotique cortico- resistant, proteine codee par ce gene et utilisations diagnostiques et therapeutiques
PCT/FR2001/000188 WO2001053347A2 (fr)	2000-01-20	2001-01-19	Gene nphs2 implique dans le syndrome nephrotique cortico-resistant, proteine codee par ce gene et utilisations diagnostiques et therapeutiques

Publications (1)

Publication Number	Publication Date
ATE466082T1 true ATE466082T1 (de)	2010-05-15

Family

ID=8846112

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT01907652T ATE466082T1 (de)	2000-01-20	2001-01-19	Das nphs2 gen, welches im corticoresistenten nephrotischen syndrome eine rolle spielt

Country Status (9)

Country	Link
US (2)	US6924110B2 (de)
EP (1)	EP1248843B1 (de)
JP (2)	JP4176993B2 (de)
AT (1)	ATE466082T1 (de)
CA (1)	CA2398083C (de)
DE (1)	DE60141947D1 (de)
ES (1)	ES2342255T3 (de)
FR (1)	FR2804127B1 (de)
WO (1)	WO2001053347A2 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2804127B1 (fr) *	2000-01-20	2004-12-24	Inst Nat Sante Rech Med	Gene srn1 implique dans le syndrome nephrotique cortico- resistant, proteine codee par ce gene et utilisations diagnostiques et therapeutiques
US20110195903A1 (en) *	2009-12-15	2011-08-11	Adra Chaker N	Methods and compositions for detecting recessive familial fsgs and uses thereof
JP5830329B2 (ja) *	2010-09-28	2015-12-09	国立大学法人岡山大学	腎障害の新規マーカー
WO2015066640A1 (en) *	2013-11-01	2015-05-07	The Research Institute At Nationwide Children's Hospital	Kit and method for identifying individual responsiveness to steroid therapy of nephrotic syndrome
WO2019084540A1 (en)	2017-10-27	2019-05-02	Zeta Biolongevity, Inc.	COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING PROTEINURY AND ENDOTHELIAL EROSION
GB201900702D0 (en)	2019-01-18	2019-03-06	Univ Bristol	Therapy
GB202003109D0 (en) *	2020-03-04	2020-04-15	Univ Bristol	Gene therapy
GB202009039D0 (en)	2020-06-15	2020-07-29	Univ Bristol	Therapy
CN113186189A (zh) *	2021-05-19	2021-07-30	中国人民解放军总医院第一医学中心	一种用于敲除猪NPHS2基因的gRNA及其相关应用
WO2025194082A1 (en) *	2024-03-15	2025-09-18	The Children's Medical Center Corporation	Compositions and methods for delivering nucleic acids to podocytes

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2804127B1 (fr) *	2000-01-20	2004-12-24	Inst Nat Sante Rech Med	Gene srn1 implique dans le syndrome nephrotique cortico- resistant, proteine codee par ce gene et utilisations diagnostiques et therapeutiques
US6812339B1 (en) *	2000-09-08	2004-11-02	Applera Corporation	Polymorphisms in known genes associated with human disease, methods of detection and uses thereof

2000
- 2000-01-20 FR FR0000709A patent/FR2804127B1/fr not_active Expired - Fee Related
2001
- 2001-01-19 AT AT01907652T patent/ATE466082T1/de not_active IP Right Cessation
- 2001-01-19 EP EP01907652A patent/EP1248843B1/de not_active Expired - Lifetime
- 2001-01-19 JP JP2001553819A patent/JP4176993B2/ja not_active Expired - Fee Related
- 2001-01-19 ES ES01907652T patent/ES2342255T3/es not_active Expired - Lifetime
- 2001-01-19 CA CA2398083A patent/CA2398083C/fr not_active Expired - Lifetime
- 2001-01-19 WO PCT/FR2001/000188 patent/WO2001053347A2/fr not_active Ceased
- 2001-01-19 DE DE60141947T patent/DE60141947D1/de not_active Expired - Lifetime
2002
- 2002-07-19 US US10/199,945 patent/US6924110B2/en not_active Expired - Lifetime
2005
- 2005-06-22 US US11/159,516 patent/US7388086B2/en not_active Expired - Lifetime
2008
- 2008-02-04 JP JP2008023877A patent/JP2008167759A/ja active Pending

Also Published As

Publication number	Publication date
JP2008167759A (ja)	2008-07-24
EP1248843B1 (de)	2010-04-28
US6924110B2 (en)	2005-08-02
WO2001053347A2 (fr)	2001-07-26
JP2004500077A (ja)	2004-01-08
DE60141947D1 (de)	2010-06-10
CA2398083A1 (fr)	2001-07-26
US7388086B2 (en)	2008-06-17
FR2804127A1 (fr)	2001-07-27
US20050266484A1 (en)	2005-12-01
ES2342255T3 (es)	2010-07-05
US20030152954A1 (en)	2003-08-14
WO2001053347A3 (fr)	2002-02-07
FR2804127B1 (fr)	2004-12-24
CA2398083C (fr)	2013-11-19
EP1248843A2 (de)	2002-10-16
JP4176993B2 (ja)	2008-11-05

Legal Events

Date	Code	Title	Description
2010-10-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties

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