ATE466574T1 - Verfahren und zusammensetzungen zur oralen fts- abgabe - Google Patents

Verfahren und zusammensetzungen zur oralen fts- abgabe

Info

Publication number
ATE466574T1
ATE466574T1 AT05787786T AT05787786T ATE466574T1 AT E466574 T1 ATE466574 T1 AT E466574T1 AT 05787786 T AT05787786 T AT 05787786T AT 05787786 T AT05787786 T AT 05787786T AT E466574 T1 ATE466574 T1 AT E466574T1
Authority
AT
Austria
Prior art keywords
fts
oral
delivery
compositions
methods
Prior art date
Application number
AT05787786T
Other languages
English (en)
Inventor
Victor Bauer
Original Assignee
Concordia Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Concordia Pharmaceuticals Inc filed Critical Concordia Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE466574T1 publication Critical patent/ATE466574T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4816—Wall or shell material
    • A61K9/4825—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C321/00—Thiols, sulfides, hydropolysulfides or polysulfides
    • C07C321/24—Thiols, sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings
    • C07C321/28—Sulfides, hydropolysulfides, or polysulfides having thio groups bound to carbon atoms of six-membered aromatic rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT05787786T 2004-08-18 2005-08-18 Verfahren und zusammensetzungen zur oralen fts- abgabe ATE466574T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60236104P 2004-08-18 2004-08-18
PCT/US2005/029389 WO2006023639A1 (en) 2004-08-18 2005-08-18 Methods and compositions for oral delivery of fts

Publications (1)

Publication Number Publication Date
ATE466574T1 true ATE466574T1 (de) 2010-05-15

Family

ID=35447506

Family Applications (2)

Application Number Title Priority Date Filing Date
AT10004111T ATE535237T1 (de) 2004-08-18 2005-08-18 Verwendung von fts zur behandlung von malignen erkrankungen
AT05787786T ATE466574T1 (de) 2004-08-18 2005-08-18 Verfahren und zusammensetzungen zur oralen fts- abgabe

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT10004111T ATE535237T1 (de) 2004-08-18 2005-08-18 Verwendung von fts zur behandlung von malignen erkrankungen

Country Status (9)

Country Link
US (4) US8088756B2 (de)
EP (3) EP2218451B1 (de)
AT (2) ATE535237T1 (de)
CA (1) CA2577310C (de)
DE (1) DE602005021115D1 (de)
ES (2) ES2414861T3 (de)
MX (1) MX2007001929A (de)
PL (1) PL1778209T3 (de)
WO (1) WO2006023639A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2414861T3 (es) 2004-08-18 2013-07-23 Kadmon Corporation, Llc Uso del FTS para el tratamiento de trastornos malignos
US8278349B2 (en) 2005-11-28 2012-10-02 Ramot At Tel-Aviv University Ltd. Cancer treatment using FTS and 2-deoxyglucose
US8268889B2 (en) 2006-02-10 2012-09-18 Ramot At Tel-Aviv University Ltd. Treatment of ovarian cancer
US20110046223A1 (en) * 2006-06-14 2011-02-24 Ramot At Tel-Aviv University Ltd. Treatment of neurofibromatosis
MX2009006574A (es) * 2006-12-19 2009-07-02 Univ Ramot Tratamiento de cancer de pulmon.
JP2013508458A (ja) * 2009-10-26 2013-03-07 ラモット・アット・テル−アヴィヴ・ユニヴァーシティ・リミテッド Ｆｔｓとｈｄａｃ阻害剤との組合せを用いたがん治療
US9738614B2 (en) 2011-10-07 2017-08-22 Pisces Therapeutics, Llc Malignant and non-malignant disease treatment with Ras antagonists
RU2632097C2 (ru) * 2011-10-07 2017-10-02 ПАЙСИЗ ТЕРАПЬЮТИКЗ ЭлЭлСи Лечение злокачественных и незлокачественных заболеваний с помощью антагонистов ras
CA3175127A1 (en) 2020-03-12 2021-09-16 Toray Industries, Inc. Medicament for treatment and/or prevention of cancer
EP4378478A4 (de) * 2021-07-27 2025-11-12 Toray Industries Medikament zur behandlung und/oder prävention von krebs

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5145684A (en) * 1991-01-25 1992-09-08 Sterling Drug Inc. Surface modified drug nanoparticles
IL107587A (en) 1993-11-12 1998-08-16 Univ Ramot Farnesyl geranyl or geranyl-geranyl derivatives pharmaceutical compositions containing them and methods for their preparation
WO1999050388A1 (en) * 1998-03-27 1999-10-07 Chong Kun Dang Corporation Streptomyces sp. producing tautomycetin and immunosuppressant comprising tautomycetin as active ingredient
AU5497000A (en) * 1999-06-18 2001-01-09 Ramot University Authority For Applied Research And Industrial Development Ltd. Non-malignant disease treatment with ras antagonists
US20020115696A1 (en) * 1999-06-18 2002-08-22 Yoel Kloog Treatment of post-angioplasty restenosis and atherosclerosis with ras antagonists
EP1325116A2 (de) * 2000-10-04 2003-07-09 RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH & INDUSTRIAL DEVELOPMENT LTD. Isoprenoid-abhängige ras-ankerproteine (idra)
US20020169183A1 (en) * 2001-03-08 2002-11-14 Villar Hugo O. Acridines as stimulators for Fas-mediated apoptosis
WO2002097114A2 (en) * 2001-05-29 2002-12-05 Sirna Therapeutics, Inc. Nucleic acid treatment of diseases or conditions related to levels of ras, her2 and hiv
US20060141472A1 (en) 2003-03-20 2006-06-29 Miikka Vikkula Medical use of ras antagonists for the treatment of capillary malformation
WO2004103352A1 (en) 2003-05-23 2004-12-02 Ramot At Tel Aviv University, Ltd. Ras antagonists for treating neurodegenerative disorders
CA2535944A1 (en) * 2003-08-22 2005-03-03 University Of Virginia Patent Foundation Blockade of mtor to prevent a hormonal adaptive response
ES2414861T3 (es) 2004-08-18 2013-07-23 Kadmon Corporation, Llc Uso del FTS para el tratamiento de trastornos malignos
US8278349B2 (en) 2005-11-28 2012-10-02 Ramot At Tel-Aviv University Ltd. Cancer treatment using FTS and 2-deoxyglucose

Also Published As

Publication number Publication date
ATE535237T1 (de) 2011-12-15
US20090226512A1 (en) 2009-09-10
CA2577310A1 (en) 2006-03-02
US20120082722A1 (en) 2012-04-05
EP2218451B1 (de) 2011-11-30
EP1778209B1 (de) 2010-05-05
MX2007001929A (es) 2007-04-17
EP2218451A1 (de) 2010-08-18
PL1778209T3 (pl) 2010-10-29
DE602005021115D1 (de) 2010-06-17
EP2301528A1 (de) 2011-03-30
US20150191426A1 (en) 2015-07-09
EP1778209A1 (de) 2007-05-02
CA2577310C (en) 2011-01-11
EP1778209B8 (de) 2010-06-16
EP2301528B1 (de) 2013-04-03
ES2414861T3 (es) 2013-07-23
US8088756B2 (en) 2012-01-03
WO2006023639A1 (en) 2006-03-02
ES2343737T3 (es) 2010-08-09
US20160271089A1 (en) 2016-09-22

Similar Documents

Publication Publication Date Title
CY1124720T1 (el) Απο του στοματος σκευασματα αναλογων κυτιδινης και μεθοδοι χρησης αυτων
FI3504187T3 (fi) Pridopidiinin käyttö toiminnallisen heikkenemisen hoitoa varten
UA110463C2 (ru) ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ 4-{[9-ХЛОР-7-(2-ФТОР-6-МЕТОКСИФЕНІЛ)-5Н-ПІРИМІДО[5,4-d][2]БЕНЗАЗЕПІН-2-ІЛ]АМІНО}-2-МЕТОКСИБЕНЗОЙНОЇ КИСЛОТИ ДЛЯ ЛІКУВАННЯ РАКУ Й ІНШИХ ЗАХВОРЮВАНЬ І ПОРУШЕНЬ СТАНУ ЗДОРОВ'Я
SG158870A1 (en) Bendamustine pharmaceutical compositions for lyophilisation
EA201100305A1 (ru) Лечение респираторных заболеваний
SI1819227T1 (sl) Farmacevtska formulacija decitabina
EA201290171A1 (ru) Вводимые перорально кортикостероидные композиции
EP2248519A3 (de) Nichtmukoadhäsive Filmdosierungsformen
WO2008022189A3 (en) Administration of high potency platinum compound formulations by inhalation
HRP20140783T1 (hr) Uporaba epotilona d u lijeäśenju tau-povezanih bolesti ukljuäśujuä†i alzheimerovu bolest
WO2008045559A3 (en) Methods of treating oral mucositis
WO2007062186A3 (en) Methods of using small molecule compounds for neuroprotection
UA107578C2 (uk) Комбінована терапія при лікуванні діабету
HRP20161197T1 (hr) 24-norudca za liječenje autoimunog hepatitisa
IL196425A0 (en) Pharmaceutical compositions containing ibuprofen and famotidine
AR045289A1 (es) Forma de dosificacion oral de liberacion controlada que comprende 4-(2-di-n-propilaminoetil) - 2(3h)-indolona (ropi-nirol) y uso de dicha forma de dosificacion para la elaboracion de un medicamento
WO2006138608A3 (en) Pharmaceutical compositions and use thereof
DE602005021115D1 (de) Verfahren und zusammensetzungen zur oralen fts-abgabe
MY148125A (en) Compounds
ATE398441T1 (de) Octenidinhaltige lutschtabletten gegen entzündliche erkrankungen des mund- und rachenraums
EA201170108A1 (ru) Сосательная композиция для лечения воспалительных заболеваний полости рта и глотки
WO2007064448A3 (en) Cancer treatment using fts and 2-deoxyglucose
WO2007144889A3 (en) Treatment of neurofibromatosis
CY1112814T1 (el) Αντιμετωπιση ανθεκτικων στα φαρμακα ογκων
ATE477021T1 (de) 1,3,5-triazepin-dionen zur behandlung von malaria

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties