ATE466835T1 - Aliphatisch substituierte demethoxylierte hypocrelline und deren herstellung - Google Patents

Aliphatisch substituierte demethoxylierte hypocrelline und deren herstellung

Info

Publication number
ATE466835T1
ATE466835T1 AT01983715T AT01983715T ATE466835T1 AT E466835 T1 ATE466835 T1 AT E466835T1 AT 01983715 T AT01983715 T AT 01983715T AT 01983715 T AT01983715 T AT 01983715T AT E466835 T1 ATE466835 T1 AT E466835T1
Authority
AT
Austria
Prior art keywords
photodynamic
production
aliphatic substituted
compositions
methods
Prior art date
Application number
AT01983715T
Other languages
English (en)
Inventor
Manhua Zhang
Shangjie Xu
Tao Wu
Shen Chen
Tao Shen
Original Assignee
Quest Pharmatech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quest Pharmatech Inc filed Critical Quest Pharmatech Inc
Application granted granted Critical
Publication of ATE466835T1 publication Critical patent/ATE466835T1/de

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K41/00Medicinal preparations obtained by treating materials with wave energy or particle radiation ; Therapies using these preparations
    • A61K41/0057Photodynamic therapy with a photosensitizer, i.e. agent able to produce reactive oxygen species upon exposure to light or radiation, e.g. UV or visible light; photocleavage of nucleic acids with an agent
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/24Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings
    • C07C225/26Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings
    • C07C225/32Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones the carbon skeleton containing carbon atoms of quinone rings having amino groups bound to carbon atoms of quinone rings or of condensed ring systems containing quinone rings of condensed quinone ring systems formed by at least three rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/06Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08Systems containing only non-condensed rings with a five-membered ring the ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2603/00Systems containing at least three condensed rings
    • C07C2603/02Ortho- or ortho- and peri-condensed systems
    • C07C2603/54Ortho- or ortho- and peri-condensed systems containing more than five condensed rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
AT01983715T 2000-10-25 2001-10-24 Aliphatisch substituierte demethoxylierte hypocrelline und deren herstellung ATE466835T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN00130048A CN1349965A (zh) 2000-10-25 2000-10-25 带有脂肪环或芳香环的脂肪胺基取代去甲氧基竹红菌素及其合成方法和用途
PCT/IB2001/001993 WO2002034708A2 (en) 2000-10-25 2001-10-24 Aliphatic amino-substituted demethoxylated hypocrellins and their synthesis

Publications (1)

Publication Number Publication Date
ATE466835T1 true ATE466835T1 (de) 2010-05-15

Family

ID=4593928

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01983715T ATE466835T1 (de) 2000-10-25 2001-10-24 Aliphatisch substituierte demethoxylierte hypocrelline und deren herstellung

Country Status (9)

Country Link
US (1) US7157477B2 (de)
EP (1) EP1328504B1 (de)
JP (1) JP2005518329A (de)
CN (2) CN1349965A (de)
AT (1) ATE466835T1 (de)
AU (2) AU1513702A (de)
CA (1) CA2426741A1 (de)
DE (1) DE60142065D1 (de)
WO (1) WO2002034708A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050143406A1 (en) * 2002-01-29 2005-06-30 Miller Gerald G. Amino-substituted hypocrellins for use as sonosensitizers
CA2615510A1 (en) * 2005-08-10 2007-02-15 Quest Pharmatech Inc. Perylenequinone derivatives and uses thereof
US8454991B2 (en) * 2006-07-24 2013-06-04 Quest Pharmatech Inc. Method and device for photodynamic therapy
US7816563B1 (en) * 2009-12-08 2010-10-19 Alberta Innovates-Technology Futures Method for preparing hypocrellin
EP3366669B1 (de) * 2015-10-21 2025-05-21 Technical Institute of Physics and Chemistry of the Chinese Academy of Sciences Monosubstituiertes oder polysubstituiertes amphiphiles hypocrellinderivat, herstellungsverfahren dafür und verwendungen davon
CN109540883A (zh) * 2018-12-27 2019-03-29 河北橘井药业有限公司 一种天竺黄的鉴定方法
CN112083090B (zh) * 2020-08-27 2022-03-22 四川新绿色药业科技发展有限公司 一种含有天竺黄或人工天竺黄中药制剂的薄层鉴别方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1081621C (zh) * 1998-04-30 2002-03-27 中国科学院感光化学研究所 胺基取代去甲氧基竹红菌素及其制法
CN1092198C (zh) * 1999-03-08 2002-10-09 中国科学院感光化学研究所 2-巯基-乙胺环化的竹红菌素及其制法和用途
US20040110846A1 (en) * 2001-01-30 2004-06-10 Beatrice Leveugle Perylenequinones for use with immunotherapy agents
US6627664B2 (en) * 2001-01-30 2003-09-30 Altachem Pharma Ltd. Perylenequinones for use as sonosensitizers
US20050143406A1 (en) * 2002-01-29 2005-06-30 Miller Gerald G. Amino-substituted hypocrellins for use as sonosensitizers

Also Published As

Publication number Publication date
JP2005518329A (ja) 2005-06-23
DE60142065D1 (de) 2010-06-17
US20040092557A1 (en) 2004-05-13
US7157477B2 (en) 2007-01-02
AU1513702A (en) 2002-05-06
CA2426741A1 (en) 2002-05-02
CN1541201A (zh) 2004-10-27
WO2002034708A2 (en) 2002-05-02
AU2002215137B2 (en) 2006-04-06
EP1328504B1 (de) 2010-05-05
CN1349965A (zh) 2002-05-22
WO2002034708A3 (en) 2003-03-13
EP1328504A2 (de) 2003-07-23

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