ATE466880T1 - Cytokinpolypeptidvarianten - Google Patents

Cytokinpolypeptidvarianten

Info

Publication number
ATE466880T1
ATE466880T1 AT04743175T AT04743175T ATE466880T1 AT E466880 T1 ATE466880 T1 AT E466880T1 AT 04743175 T AT04743175 T AT 04743175T AT 04743175 T AT04743175 T AT 04743175T AT E466880 T1 ATE466880 T1 AT E466880T1
Authority
AT
Austria
Prior art keywords
amino acid
ligand
native
cytokine
terminal
Prior art date
Application number
AT04743175T
Other languages
English (en)
Inventor
Jon Sayers
Peter Artymuik
Richard Ross
Original Assignee
Asterion Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asterion Ltd filed Critical Asterion Ltd
Application granted granted Critical
Publication of ATE466880T1 publication Critical patent/ATE466880T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • A61P5/10Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/61Growth hormone [GH], i.e. somatotropin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Error Detection And Correction (AREA)
AT04743175T 2003-06-28 2004-06-28 Cytokinpolypeptidvarianten ATE466880T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0315182.6A GB0315182D0 (en) 2003-06-28 2003-06-28 Cytokine variant polypeptides
PCT/GB2004/002827 WO2005003165A2 (en) 2003-06-28 2004-06-28 Cytokine variant polypeptides

Publications (1)

Publication Number Publication Date
ATE466880T1 true ATE466880T1 (de) 2010-05-15

Family

ID=27676290

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04743175T ATE466880T1 (de) 2003-06-28 2004-06-28 Cytokinpolypeptidvarianten

Country Status (8)

Country Link
US (1) US20070264234A1 (de)
EP (1) EP1639002B1 (de)
JP (1) JP2008504001A (de)
AT (1) ATE466880T1 (de)
CA (1) CA2568859A1 (de)
DE (1) DE602004027039D1 (de)
GB (1) GB0315182D0 (de)
WO (1) WO2005003165A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1771467A2 (de) * 2004-07-26 2007-04-11 Asterion Limited Linker
GB0606946D0 (en) * 2006-04-06 2006-05-17 Asterion Ltd Polypeptide antagonist
US9885050B2 (en) * 2007-11-08 2018-02-06 The University Of Chicago Molecular affinity clamp technology and uses thereof
WO2010024557A2 (en) * 2008-08-25 2010-03-04 Viromed Co., Ltd. Biopolymer conjugates comprising an interleukin-11 analog
KR101853405B1 (ko) * 2010-10-20 2018-05-02 주식회사 티움바이오 인자 ix 활성을 갖는 융합 단백질
US9156897B2 (en) * 2012-06-08 2015-10-13 Alkermes, Inc. Fusion polypeptides comprising an active protein linked to a mucin-domain polypeptide
US11680091B2 (en) 2018-02-23 2023-06-20 The University Of Chicago Methods and composition involving thermophilic fibronectin type III (FN3) monobodies
MX2023011268A (es) 2021-03-24 2023-12-14 Alkermes Inc Anticuerpos upar y proteínas de fusión con estos.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5635599A (en) * 1994-04-08 1997-06-03 The United States Of America As Represented By The Department Of Health And Human Services Fusion proteins comprising circularly permuted ligands
DK0851925T3 (da) * 1995-09-21 2005-11-28 Genentech Inc Humane Væksthormonvarianter
BR9811755A (pt) * 1997-09-08 2000-08-29 Metabolic Pharmaceutical Ltd Peptìdeo, processo para o tratamento da obesidade em um animal, uso de um peptìdeo, e, composição farmacêutica
EP1115854A1 (de) * 1998-09-25 2001-07-18 G.D. Searle & Co. Methode zur herstellung von permuteinen durch scanning permutagenese
AU2003256566A1 (en) * 2002-07-16 2004-02-02 Stuart Bussell Methods to construct multimeric dna and polymeric protein sequences as direct fusions or with linkers

Also Published As

Publication number Publication date
JP2008504001A (ja) 2008-02-14
WO2005003165A3 (en) 2005-07-14
EP1639002B1 (de) 2010-05-05
EP1639002A2 (de) 2006-03-29
CA2568859A1 (en) 2005-01-13
DE602004027039D1 (de) 2010-06-17
WO2005003165A2 (en) 2005-01-13
US20070264234A1 (en) 2007-11-15
GB0315182D0 (en) 2003-08-06

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Legal Events

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