ATE466880T1 - Cytokinpolypeptidvarianten - Google Patents
CytokinpolypeptidvariantenInfo
- Publication number
- ATE466880T1 ATE466880T1 AT04743175T AT04743175T ATE466880T1 AT E466880 T1 ATE466880 T1 AT E466880T1 AT 04743175 T AT04743175 T AT 04743175T AT 04743175 T AT04743175 T AT 04743175T AT E466880 T1 ATE466880 T1 AT E466880T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- ligand
- native
- cytokine
- terminal
- Prior art date
Links
- 102000004127 Cytokines Human genes 0.000 title abstract 3
- 108090000695 Cytokines Proteins 0.000 title abstract 3
- 239000003446 ligand Substances 0.000 abstract 4
- 125000003275 alpha amino acid group Chemical class 0.000 abstract 2
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/10—Drugs for disorders of the endocrine system of the posterior pituitary hormones, e.g. oxytocin, ADH
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/61—Growth hormone [GH], i.e. somatotropin
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Endocrinology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Diabetes (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Error Detection And Correction (AREA)
- Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0315182.6A GB0315182D0 (en) | 2003-06-28 | 2003-06-28 | Cytokine variant polypeptides |
| PCT/GB2004/002827 WO2005003165A2 (en) | 2003-06-28 | 2004-06-28 | Cytokine variant polypeptides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE466880T1 true ATE466880T1 (de) | 2010-05-15 |
Family
ID=27676290
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT04743175T ATE466880T1 (de) | 2003-06-28 | 2004-06-28 | Cytokinpolypeptidvarianten |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US20070264234A1 (de) |
| EP (1) | EP1639002B1 (de) |
| JP (1) | JP2008504001A (de) |
| AT (1) | ATE466880T1 (de) |
| CA (1) | CA2568859A1 (de) |
| DE (1) | DE602004027039D1 (de) |
| GB (1) | GB0315182D0 (de) |
| WO (1) | WO2005003165A2 (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006010891A2 (en) * | 2004-07-26 | 2006-02-02 | Asterion Limited | Linkers |
| GB0606946D0 (en) * | 2006-04-06 | 2006-05-17 | Asterion Ltd | Polypeptide antagonist |
| WO2009062170A1 (en) * | 2007-11-08 | 2009-05-14 | The University Of Chicago | Molecular affinity clamp technology and uses thereof |
| MX2011002055A (es) * | 2008-08-25 | 2011-03-30 | Viromed Co Ltd | Conjugados de biopolimeros que contienen un analogo de interleucina-11. |
| KR101853405B1 (ko) | 2010-10-20 | 2018-05-02 | 주식회사 티움바이오 | 인자 ｉｘ 활성을 갖는 융합 단백질 |
| LT3401402T (lt) * | 2012-06-08 | 2020-12-28 | Alkermes Pharma Ireland Limited | Ligandai, modifikuoti cirkuliarinės permutacijos pagalba, kaip agonistai ir antagonistai |
| WO2019165017A1 (en) | 2018-02-23 | 2019-08-29 | The University Of Chicago | Methods and composition involving thermophilic fibronectin type iii (fn3) monobodies |
| CN117440972A (zh) | 2021-03-24 | 2024-01-23 | 奥克梅斯公司 | Upar抗体和具有所述抗体的融合蛋白 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5635599A (en) * | 1994-04-08 | 1997-06-03 | The United States Of America As Represented By The Department Of Health And Human Services | Fusion proteins comprising circularly permuted ligands |
| JP3628333B2 (ja) * | 1995-09-21 | 2005-03-09 | ジェネンテック インコーポレーテッド | ヒト成長ホルモン変異体 |
| DE69838647T2 (de) * | 1997-09-08 | 2008-08-28 | Metabolic Pharmaceuticals Ltd., Melbourne | Behandlung von fettleibigkeit |
| WO2000018905A1 (en) * | 1998-09-25 | 2000-04-06 | G.D. Searle & Co. | Method of producing permuteins by scanning permutagenesis |
| US20040059093A1 (en) * | 2002-07-16 | 2004-03-25 | Stuart Bussell | Methods to construct multimeric DNA and polymeric protein sequences as direct fusions or with linkers |
-
2003
- 2003-06-28 GB GBGB0315182.6A patent/GB0315182D0/en not_active Ceased
-
2004
- 2004-06-28 WO PCT/GB2004/002827 patent/WO2005003165A2/en not_active Ceased
- 2004-06-28 AT AT04743175T patent/ATE466880T1/de not_active IP Right Cessation
- 2004-06-28 DE DE602004027039T patent/DE602004027039D1/de not_active Expired - Fee Related
- 2004-06-28 EP EP04743175A patent/EP1639002B1/de not_active Expired - Lifetime
- 2004-06-28 JP JP2006518330A patent/JP2008504001A/ja active Pending
- 2004-06-28 CA CA002568859A patent/CA2568859A1/en not_active Abandoned
- 2004-06-28 US US10/561,831 patent/US20070264234A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1639002A2 (de) | 2006-03-29 |
| WO2005003165A2 (en) | 2005-01-13 |
| WO2005003165A3 (en) | 2005-07-14 |
| CA2568859A1 (en) | 2005-01-13 |
| US20070264234A1 (en) | 2007-11-15 |
| EP1639002B1 (de) | 2010-05-05 |
| JP2008504001A (ja) | 2008-02-14 |
| DE602004027039D1 (de) | 2010-06-17 |
| GB0315182D0 (en) | 2003-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |