ATE468130T1 - Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie - Google Patents

Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie

Info

Publication number
ATE468130T1
ATE468130T1 AT02762584T AT02762584T ATE468130T1 AT E468130 T1 ATE468130 T1 AT E468130T1 AT 02762584 T AT02762584 T AT 02762584T AT 02762584 T AT02762584 T AT 02762584T AT E468130 T1 ATE468130 T1 AT E468130T1
Authority
AT
Austria
Prior art keywords
use against
against virus
inhibitors via
induced immunopathology
stimulation inhibitors
Prior art date
Application number
AT02762584T
Other languages
English (en)
Inventor
Tracey Hussell
Ian Humphreys
Original Assignee
Imp College Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imp College Innovations Ltd filed Critical Imp College Innovations Ltd
Application granted granted Critical
Publication of ATE468130T1 publication Critical patent/ATE468130T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Cell Biology (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT02762584T 2001-09-27 2002-09-27 Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie ATE468130T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0123276.8A GB0123276D0 (en) 2001-09-27 2001-09-27 Uses of agents that bind immune-system components
PCT/GB2002/004386 WO2003026693A2 (en) 2001-09-27 2002-09-27 Inhibitors of costimulation by 0x40 and their use against infectious diseases

Publications (1)

Publication Number Publication Date
ATE468130T1 true ATE468130T1 (de) 2010-06-15

Family

ID=9922822

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02762584T ATE468130T1 (de) 2001-09-27 2002-09-27 Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie

Country Status (7)

Country Link
US (1) US20050069548A1 (de)
EP (1) EP1429804B1 (de)
AT (1) ATE468130T1 (de)
AU (1) AU2002327970A1 (de)
DE (1) DE60236443D1 (de)
GB (1) GB0123276D0 (de)
WO (1) WO2003026693A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7812133B2 (en) 2005-12-16 2010-10-12 Genentech, Inc Anti-OX40L antibodies and methods using same
MX2008015771A (es) * 2006-06-14 2009-01-27 Macrogenics Inc Metodos para el tratamiento de padecimientos autoinmunes usando anticuerpos monoclonales con toxicidad reducida.
BRPI1008692B8 (pt) 2009-02-17 2021-05-25 Ucb Biopharma Sprl anticorpo antagonista tendo especificidade para ox40 humano, sequência de dna isolado, vetor de clonagem ou de expressão, célula hospedeira, processo para a produção do referido anticorpo, composição farmacêutica, uso do 5 referido anticorpo e proteína de fusão
US9221895B2 (en) * 2009-03-13 2015-12-29 The Trustees Of The University Of Pennsylvania OX40/TRAIL fusion proteins
WO2020056045A1 (en) * 2018-09-13 2020-03-19 Nkarta, Inc. Natural killer cell compositions and immunotherapy methods for treating tumors
WO2020180882A1 (en) 2019-03-05 2020-09-10 Nkarta, Inc. Cd19-directed chimeric antigen receptors and uses thereof in immunotherapy
CN115028628B (zh) * 2022-06-22 2023-10-10 中南大学 一种rsv-f蛋白小分子抑制剂及其在制备防治rsv感染药物中应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166057A (en) 1989-08-28 1992-11-24 The Mount Sinai School Of Medicine Of The City University Of New York Recombinant negative strand rna virus expression-systems
US5821332A (en) 1993-11-03 1998-10-13 The Board Of Trustees Of The Leland Stanford Junior University Receptor on the surface of activated CD4+ T-cells: ACT-4
US6242566B1 (en) * 1994-02-10 2001-06-05 Board Of Trustees Of The Leland Stanford Junior University Ligand (ACT-4-L) to a receptor on the surface of activated CD4+ T-cells

Also Published As

Publication number Publication date
DE60236443D1 (de) 2010-07-01
AU2002327970A1 (en) 2003-04-07
EP1429804A2 (de) 2004-06-23
EP1429804B1 (de) 2010-05-19
WO2003026693A3 (en) 2003-12-18
WO2003026693A2 (en) 2003-04-03
GB0123276D0 (en) 2001-11-21
US20050069548A1 (en) 2005-03-31

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