ATE468130T1 - Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie - Google Patents

Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie

Info

Publication number
ATE468130T1
ATE468130T1 AT02762584T AT02762584T ATE468130T1 AT E468130 T1 ATE468130 T1 AT E468130T1 AT 02762584 T AT02762584 T AT 02762584T AT 02762584 T AT02762584 T AT 02762584T AT E468130 T1 ATE468130 T1 AT E468130T1
Authority
AT
Austria
Prior art keywords
use against
against virus
inhibitors via
induced immunopathology
stimulation inhibitors
Prior art date
Application number
AT02762584T
Other languages
English (en)
Inventor
Tracey Hussell
Ian Humphreys
Original Assignee
Imp College Innovations Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imp College Innovations Ltd filed Critical Imp College Innovations Ltd
Application granted granted Critical
Publication of ATE468130T1 publication Critical patent/ATE468130T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT02762584T 2001-09-27 2002-09-27 Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie ATE468130T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0123276.8A GB0123276D0 (en) 2001-09-27 2001-09-27 Uses of agents that bind immune-system components
PCT/GB2002/004386 WO2003026693A2 (en) 2001-09-27 2002-09-27 Inhibitors of costimulation by 0x40 and their use against infectious diseases

Publications (1)

Publication Number Publication Date
ATE468130T1 true ATE468130T1 (de) 2010-06-15

Family

ID=9922822

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02762584T ATE468130T1 (de) 2001-09-27 2002-09-27 Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie

Country Status (7)

Country Link
US (1) US20050069548A1 (de)
EP (1) EP1429804B1 (de)
AT (1) ATE468130T1 (de)
AU (1) AU2002327970A1 (de)
DE (1) DE60236443D1 (de)
GB (1) GB0123276D0 (de)
WO (1) WO2003026693A2 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2426744C2 (ru) 2005-12-16 2011-08-20 Дженентек, Инк. Антитела к ox40l и способы их применения
SG10201504662WA (en) * 2006-06-14 2015-07-30 Macrogenics Inc Methods For The Treatment Of Autoimmune Disorders Using Immunosuppressive Monoclonal Antibodies With Reduced Toxicity
US8614295B2 (en) * 2009-02-17 2013-12-24 Ucb Pharma S.A. Antibody molecules having specificity for human OX40
CA2755198A1 (en) * 2009-03-13 2010-09-16 Mark L. Tykocinski Ox40/trail fusion proteins
US20210338727A1 (en) * 2018-09-13 2021-11-04 Nkarta, Inc. Natural killer cell compositions and immunotherapy methods for treating tumors
AU2020232691B2 (en) 2019-03-05 2023-06-29 Nkarta, Inc. CD19-directed chimeric antigen receptors and uses thereof in immunotherapy
CN115028628B (zh) * 2022-06-22 2023-10-10 中南大学 一种rsv-f蛋白小分子抑制剂及其在制备防治rsv感染药物中应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5166057A (en) 1989-08-28 1992-11-24 The Mount Sinai School Of Medicine Of The City University Of New York Recombinant negative strand rna virus expression-systems
US5821332A (en) 1993-11-03 1998-10-13 The Board Of Trustees Of The Leland Stanford Junior University Receptor on the surface of activated CD4+ T-cells: ACT-4
US6242566B1 (en) * 1994-02-10 2001-06-05 Board Of Trustees Of The Leland Stanford Junior University Ligand (ACT-4-L) to a receptor on the surface of activated CD4+ T-cells

Also Published As

Publication number Publication date
GB0123276D0 (en) 2001-11-21
AU2002327970A1 (en) 2003-04-07
WO2003026693A2 (en) 2003-04-03
EP1429804B1 (de) 2010-05-19
US20050069548A1 (en) 2005-03-31
WO2003026693A3 (en) 2003-12-18
DE60236443D1 (de) 2010-07-01
EP1429804A2 (de) 2004-06-23

Similar Documents

Publication Publication Date Title
DK1556021T3 (da) Farmaceutiske sammensætninger omfattende flavonoider og menthol samt fremgangsmåder til behandling med brug af nævnte sammensætninger
ATE322265T1 (de) Pharmazeutische zusammensetzung zur behandlung von kolorektalem krebs welche thalidomid und irinotecan enthält
CL2004000930A1 (es) Compuesto derivado de dihidroquinazolina de formula definida, util para el tratamiento y/o profilaxis de infecciones virales; composicion farmaceutica que comprende al compuesto y uso del compuesto en la preparacion de medicamentos.
DE602004032522D1 (de) Mit n-alkylhydroxamsäuren substituierte isoindolylverbindungen und deren pharmazeutische verwendung
TR200500745T2 (tr) Damar gelişimi inhibitörleri olarak kuinazolin türevleri.
DE60321929D1 (de) Pharmazeutische zusammensetzungen mit dextromethorphan und chinidin zur behandlung von neurologischen erkrankungen
EA199901031A1 (ru) Производные бензимидазола
ATE544866T1 (de) Adamts13-haltige zusammensetzungen mit thrombolytischer wirkung
DE69919179D1 (de) Substituierte gamma-phenyl-delta-lactone und deren analoge, und ihre verwendungen
EA200970916A1 (ru) Соединения 5,6-дигидро-1н-пиридин-2-она
ATE486634T1 (de) Caspase 3, 8, 9 oder 10 inhibitoren in kombination mit mek inhibitoren zur behandlung von influenza
DE602004017326D1 (de) Tetrahydrocarbazolderivate und deren pharmazeutische verwendung
DE60326069D1 (de) 4-(heterocyclyl)-benzenesulfoximin verbindungen zur behandlung entzündlicher erkrankungenen
ATE468130T1 (de) Inhibitoren der kostimulation via ox40 und deren verwendung gegen eine von virusen induzierten immunpathologie
DE602004025689D1 (de) Antivirale mittel zur behandlung, kontrolle und prävention von infektionen durch coronaviren
EA199800526A1 (ru) Производные бензимидазола и их применение для лечения вирусных инфекций
DE69429856D1 (de) Substituierte caprolactame und deren derivate verwendbar zur behandlung der hiv-krankheit
ATE303816T1 (de) Neue therapeutische verwendung eines eine virale ansteckung modulierendes protein zur verhinderung von abstossung von fremdtransplantaten
ATE505464T1 (de) Feste form von amg 706 und pharmazeutische zusammensetzungen davon
BRPI0410967A (pt) compostos, composições e seus usos para o tratamento de infecções por vìrus da famìlia flaviviridae
DK0722325T3 (da) Præparat til behandling eller forebyggelse af herpes
SE0203817D0 (sv) New composition
ATE410154T1 (de) Pharmazeutische zusammensetzung enthaltend 2,4- dichlorbenzylalkohol und amylmetakresol
CL2004001461A1 (es) Compuestos derivados de 1,2,3,4-tetrahidropirimidina, composicion farmaceutica y su procedimiento de preparacion, procedimiento de preparacion, utiles para tratar o prevenir la hepatitis c.
ATE544453T1 (de) Kombinationstherapien mit l-fmau zur behandlung von hepatitis-b-virus-infektionen

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties