ATE468329T1 - Isoxazolderivate und deren verwendung als cyclooxygenaseinhibitoren - Google Patents

Isoxazolderivate und deren verwendung als cyclooxygenaseinhibitoren

Info

Publication number
ATE468329T1
ATE468329T1 AT05702217T AT05702217T ATE468329T1 AT E468329 T1 ATE468329 T1 AT E468329T1 AT 05702217 T AT05702217 T AT 05702217T AT 05702217 T AT05702217 T AT 05702217T AT E468329 T1 ATE468329 T1 AT E468329T1
Authority
AT
Austria
Prior art keywords
cyclooxygenase inhibitors
isoxazole derivatives
cyclooxygenase
inhibitors
cox
Prior art date
Application number
AT05702217T
Other languages
English (en)
Inventor
Antonio Scilimati
Nunno Leonardo Di
Paola Vitale
Paola Patrignani
Stefania Tacconelli
Ettore Porreca
Liborio Stuppia
Original Assignee
Univ Bari
Uni Degli Studi Di Chieti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Bari, Uni Degli Studi Di Chieti filed Critical Univ Bari
Application granted granted Critical
Publication of ATE468329T1 publication Critical patent/ATE468329T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/08—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05702217T 2004-01-12 2005-01-12 Isoxazolderivate und deren verwendung als cyclooxygenaseinhibitoren ATE468329T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT000019A ITMI20040019A1 (it) 2004-01-12 2004-01-12 Derivati isossazolici e loro impiego come inibitori della ciclossigenasi
PCT/IB2005/000047 WO2005068442A2 (en) 2004-01-12 2005-01-12 Isoxazole derivatives and their use as cyclooxygenase inhibitors

Publications (1)

Publication Number Publication Date
ATE468329T1 true ATE468329T1 (de) 2010-06-15

Family

ID=34779432

Family Applications (2)

Application Number Title Priority Date Filing Date
AT10005150T ATE538107T1 (de) 2004-01-12 2005-01-12 Isoxazol-derivate zur anwendung als cyclooxygenase-inhibitoren
AT05702217T ATE468329T1 (de) 2004-01-12 2005-01-12 Isoxazolderivate und deren verwendung als cyclooxygenaseinhibitoren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT10005150T ATE538107T1 (de) 2004-01-12 2005-01-12 Isoxazol-derivate zur anwendung als cyclooxygenase-inhibitoren

Country Status (7)

Country Link
EP (2) EP2246337B1 (de)
AT (2) ATE538107T1 (de)
DE (1) DE602005021309D1 (de)
DK (1) DK1706390T3 (de)
ES (1) ES2344738T3 (de)
IT (1) ITMI20040019A1 (de)
WO (1) WO2005068442A2 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7943588B2 (en) 2006-03-28 2011-05-17 Trustees Of Dartmouth College Method for preventing or treating neuropathic pain
US7989450B2 (en) 2008-01-11 2011-08-02 Universita' Degli Studi Di Bari Functionalized diarylisoxazoles inhibitors of ciclooxygenase

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1128526A (en) * 1979-10-05 1982-07-27 Cdc Life Sciences Inc. 3,4-diarylisoxazol-5-acetic acids
JPH04134077A (ja) * 1990-09-21 1992-05-07 Taiho Yakuhin Kogyo Kk イソオキサゾール化合物
EP0633254A1 (de) * 1991-05-01 1995-01-11 Taiho Pharmaceutical Co., Ltd. Neue isoxazolderivate und ihre salze
RO119946B1 (ro) * 1995-02-13 2005-06-30 G.D. Searle & Co. Derivaţi de izoxazol, utilizaţi pentru tratamentul inflamaţiilor
ES2248894T3 (es) * 1997-04-21 2006-03-16 Dainippon Sumitomo Pharma Co., Ltd. Derivados de isoxazol.
JP2003531202A (ja) * 2000-04-25 2003-10-21 ファルマシア・コーポレーション ３，４−ジ（カルボシクリルまたはヘテロシクリル）チオフェンの位置選択的合成
US20030105144A1 (en) * 2001-04-17 2003-06-05 Ping Gao Stabilized oral pharmaceutical composition
US6673818B2 (en) * 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
CA2462297C (en) * 2001-10-02 2009-04-07 Pharmacia Corporation Method for preparing benzenesulfonyl compounds
JP2005510479A (ja) * 2001-10-12 2005-04-21 オンコノバ・セラピューティックス・インコーポレーテッド 置換イソオキサゾールおよび置換２−イソオキサゾリンを調製する方法
WO2003078408A1 (en) * 2002-03-15 2003-09-25 Pharmacia Corporation Crystalline parecoxib sodium
ATE422201T1 (de) * 2002-04-05 2009-02-15 Cadila Healthcare Ltd 4-(heterocyclyl)-benzenesulfoximin verbindungen zur behandlung entzündlicher erkrankungenen
DE10237883A1 (de) * 2002-08-19 2004-03-04 Merckle Gmbh Chem.-Pharm. Fabrik Substituierte Isoxazolderivate und ihre Verwendung in der Pharmazie
AU2003278039A1 (en) * 2002-10-22 2004-05-13 Merck Frosst Canada And Co. Nitric oxide releasing selective cyclooxygenase-2 inhibitors
HUP0302219A2 (hu) * 2003-07-16 2005-03-29 Richter Gedeon Vegyészeti Gyár Rt. N-hidroxi-4-(3-fenil-5-metil-izoxazol-4-il)-benzolszulfonamid-szolvátok, eljárás előállításukra és alkalmazásuk

Also Published As

Publication number Publication date
DK1706390T3 (da) 2010-08-23
EP1706390B1 (de) 2010-05-19
ITMI20040019A1 (it) 2004-04-12
ATE538107T1 (de) 2012-01-15
ES2344738T3 (es) 2010-09-06
WO2005068442A2 (en) 2005-07-28
EP2246337A1 (de) 2010-11-03
EP2246337B1 (de) 2011-12-21
EP1706390A2 (de) 2006-10-04
WO2005068442A3 (en) 2006-04-06
DE602005021309D1 (de) 2010-07-01

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Legal Events

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