ATE468351T1 - Peptidaptamer zum neutralisieren der bindung von platelet-antigen-spezifischen antikörpern und diagnostische und therapeutische anwendungen, die dieses enthalten - Google Patents

Peptidaptamer zum neutralisieren der bindung von platelet-antigen-spezifischen antikörpern und diagnostische und therapeutische anwendungen, die dieses enthalten

Info

Publication number
ATE468351T1
ATE468351T1 AT07703325T AT07703325T ATE468351T1 AT E468351 T1 ATE468351 T1 AT E468351T1 AT 07703325 T AT07703325 T AT 07703325T AT 07703325 T AT07703325 T AT 07703325T AT E468351 T1 ATE468351 T1 AT E468351T1
Authority
AT
Austria
Prior art keywords
specific antibodies
neutralizing
binding
peptide aptamer
diagnostic
Prior art date
Application number
AT07703325T
Other languages
English (en)
Inventor
Dominique Rigal
Julien Thibaut
Gemain Gillet
Yves Merieux
Original Assignee
Diagnostische Forsch Stiftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diagnostische Forsch Stiftung filed Critical Diagnostische Forsch Stiftung
Application granted granted Critical
Publication of ATE468351T1 publication Critical patent/ATE468351T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/745—Assays involving non-enzymic blood coagulation factors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/02—Screening involving studying the effect of compounds C on the interaction between interacting molecules A and B (e.g. A = enzyme and B = substrate for A, or A = receptor and B = ligand for the receptor)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/22—Haematology
    • G01N2800/222—Platelet disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
AT07703325T 2006-02-07 2007-02-07 Peptidaptamer zum neutralisieren der bindung von platelet-antigen-spezifischen antikörpern und diagnostische und therapeutische anwendungen, die dieses enthalten ATE468351T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06002496 2006-02-07
PCT/EP2007/001042 WO2007090630A2 (en) 2006-02-07 2007-02-07 Peptide aptamer for neutralizing the binding of platelet antigene specific antibodies and diagnostic and therapeutic applications containing the same

Publications (1)

Publication Number Publication Date
ATE468351T1 true ATE468351T1 (de) 2010-06-15

Family

ID=38223347

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07703325T ATE468351T1 (de) 2006-02-07 2007-02-07 Peptidaptamer zum neutralisieren der bindung von platelet-antigen-spezifischen antikörpern und diagnostische und therapeutische anwendungen, die dieses enthalten

Country Status (8)

Country Link
US (2) US8183055B2 (de)
EP (1) EP1987057B1 (de)
JP (1) JP5042237B2 (de)
AT (1) ATE468351T1 (de)
DE (1) DE602007006634D1 (de)
DK (1) DK1987057T3 (de)
ES (1) ES2345569T3 (de)
WO (1) WO2007090630A2 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0717166D0 (en) * 2007-09-04 2007-10-17 Univ Brighton Method for stabilisation of purified P-Glycoprotein
JP5210620B2 (ja) * 2007-12-19 2013-06-12 独立行政法人科学技術振興機構 ペプチドアプタマーライブラリーの作製方法および用途
US9598281B2 (en) 2011-03-03 2017-03-21 The Regents Of The University Of California Nanopipette apparatus for manipulating cells
DK2796881T3 (en) * 2013-04-26 2018-01-02 Davos Diagnostics Ag Platelet allogeneic antigen type and platelet antibody test.
CA2943857C (en) 2014-03-31 2023-07-11 Universitetet I Tromso - Norges Arktiske Universitet Antibodies against hpa-1a
CN111175488A (zh) * 2020-03-24 2020-05-19 天津美瑞特医疗科技有限公司 一种应用流式细胞术检测血小板抗体特异性的方法及检测试剂盒
CA3181176A1 (en) * 2020-04-27 2021-11-04 CCOA Therapeutics Inc. Rapid and facile antibody detection using covalently immobilized self-assembled polypeptides
IL330389A (en) * 2023-12-29 2026-08-01 Yyz Pharmatech Inc Method for generating and screening synthetic peptide aptamer libraries

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9223390D0 (en) 1992-11-07 1992-12-23 Common Services Agency Anti-hpa1 testing

Also Published As

Publication number Publication date
EP1987057A2 (de) 2008-11-05
DE602007006634D1 (de) 2010-07-01
US8183055B2 (en) 2012-05-22
WO2007090630A3 (en) 2007-09-20
ES2345569T3 (es) 2010-09-27
WO2007090630A2 (en) 2007-08-16
JP2009525725A (ja) 2009-07-16
US20120245338A1 (en) 2012-09-27
EP1987057B1 (de) 2010-05-19
US20090318363A1 (en) 2009-12-24
JP5042237B2 (ja) 2012-10-03
US8563704B2 (en) 2013-10-22
DK1987057T3 (da) 2010-08-30

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Legal Events

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