ATE469964T1 - Zusammensetzungen mit rekombinantem tollwutvirus - Google Patents

Zusammensetzungen mit rekombinantem tollwutvirus

Info

Publication number: ATE469964T1
Authority: AT; Austria
Prior art keywords: amino acid; recombinant rabies; pathogenic; viruses; compositions containing
Prior art date: 2004-07-12

Application number

AT05790962T

Other languages

English (en)

Inventor

Bernhard Dietzschold

Marie Luise Faber

Milosz Faber

Matthias Schnell

Original Assignee

Univ Jefferson

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-07-12

Filing date

2005-07-12

Publication date

2010-06-15

2005-07-12 Application filed by Univ Jefferson filed Critical Univ Jefferson

2010-06-15 Application granted granted Critical

2010-06-15 Publication of ATE469964T1 publication Critical patent/ATE469964T1/de

Links

241000711798 Rabies lyssavirus Species 0.000 title abstract 3
239000000203 mixture Substances 0.000 title 1
241000700605 Viruses Species 0.000 abstract 3
235000001014 amino acid Nutrition 0.000 abstract 3
230000001717 pathogenic effect Effects 0.000 abstract 3
DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 abstract 2
KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 abstract 2
241000699670 Mus sp. Species 0.000 abstract 2
IQFYYKKMVGJFEH-XLPZGREQSA-N Thymidine Chemical compound O=C1NC(=O)C(C)=CN1[C@@H]1O[C@H](CO)[C@@H](O)C1 IQFYYKKMVGJFEH-XLPZGREQSA-N 0.000 abstract 2
OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 abstract 2
125000003275 alpha amino acid group Chemical group 0.000 abstract 2
229960001230 asparagine Drugs 0.000 abstract 2
235000009582 asparagine Nutrition 0.000 abstract 2
DWRXFEITVBNRMK-UHFFFAOYSA-N Beta-D-1-Arabinofuranosylthymine Natural products O=C1NC(=O)C(C)=CN1C1C(O)C(O)C(CO)O1 DWRXFEITVBNRMK-UHFFFAOYSA-N 0.000 abstract 1
239000002126 C01EB10 - Adenosine Substances 0.000 abstract 1
108020004705 Codon Proteins 0.000 abstract 1
101150082239 G gene Proteins 0.000 abstract 1
102000003886 Glycoproteins Human genes 0.000 abstract 1
108090000288 Glycoproteins Proteins 0.000 abstract 1
DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 abstract 1
239000004472 Lysine Substances 0.000 abstract 1
241000124008 Mammalia Species 0.000 abstract 1
229960005305 adenosine Drugs 0.000 abstract 1
229940024606 amino acid Drugs 0.000 abstract 1
150000001413 amino acids Chemical class 0.000 abstract 1
125000000637 arginyl group Chemical group N[C@@H](CCCNC(N)=N)C(=O)* 0.000 abstract 1
125000000613 asparagine group Chemical group N[C@@H](CC(N)=O)C(=O)* 0.000 abstract 1
IQFYYKKMVGJFEH-UHFFFAOYSA-N beta-L-thymidine Natural products O=C1NC(=O)C(C)=CN1C1OC(CO)C(O)C1 IQFYYKKMVGJFEH-UHFFFAOYSA-N 0.000 abstract 1
208000015181 infectious disease Diseases 0.000 abstract 1
125000003588 lysine group Chemical group [H]N([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])(N([H])[H])C(*)=O 0.000 abstract 1
230000035772 mutation Effects 0.000 abstract 1
238000002741 site-directed mutagenesis Methods 0.000 abstract 1
229940104230 thymidine Drugs 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/13—Tumour cells, irrespective of tissue of origin
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20121—Viruses as such, e.g. new isolates, mutants or their genomic sequences
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/20011—Rhabdoviridae
- C12N2760/20111—Lyssavirus, e.g. rabies virus
- C12N2760/20161—Methods of inactivation or attenuation

Landscapes

Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Genetics & Genomics (AREA)
Zoology (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Wood Science & Technology (AREA)
Bioinformatics & Cheminformatics (AREA)
Virology (AREA)
Biophysics (AREA)
Immunology (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Gastroenterology & Hepatology (AREA)
General Engineering & Computer Science (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)

AT05790962T 2004-07-12 2005-07-12 Zusammensetzungen mit rekombinantem tollwutvirus ATE469964T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US58712904P	2004-07-12	2004-07-12
PCT/US2005/024671 WO2006017276A2 (en)	2004-07-12	2005-07-12	Recombinant rabies virus compositions

Publications (1)

Publication Number	Publication Date
ATE469964T1 true ATE469964T1 (de)	2010-06-15

Family

ID=35839783

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT05790962T ATE469964T1 (de)	2004-07-12	2005-07-12	Zusammensetzungen mit rekombinantem tollwutvirus

Country Status (9)

Country	Link
US (1)	US7695724B2 (de)
EP (1)	EP1768697B1 (de)
AT (1)	ATE469964T1 (de)
CA (1)	CA2573631A1 (de)
DE (1)	DE602005021636D1 (de)
MX (1)	MX2007000445A (de)
RS (1)	RS51371B (de)
WO (1)	WO2006017276A2 (de)
ZA (1)	ZA200700323B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU2003234090A1 (en) *	2002-04-11	2003-10-27	Medimmune Vaccines, Inc.	Spray freeze dry of compositions for pulmonary administration
BRPI0919174B1 (pt) *	2008-09-17	2020-11-17	The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services, Centers For Disease Control And Prevention	vírus da raiva recombinante, composição imunogênica e seu uso
US8282939B2 (en) *	2009-09-11	2012-10-09	Thomas Jefferson University	Attenuated live triple G protein recombinant rabies virus vaccine for pre- and post-exposure prophylaxis of rabies
US11060068B2 (en) *	2011-06-28	2021-07-13	Leukocare Ag	Stabilisation method for viruses or bacteria
RU2660566C2 (ru)	2012-10-01	2018-07-06	Томас Джефферсон Юниверсити	Иммунизация вектором на основе вируса бешенства, экспрессирующим чужеродный белковый антиген
WO2015059284A1 (en) *	2013-10-25	2015-04-30	Leukocare Ag	A novel method for the production of stabile vaccines
CN109517809B (zh) *	2018-11-30	2022-03-22	华南农业大学	一株缺失e蛋白离子通道活性的传染性支气管炎重组病毒及制备方法与应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2693655B1 (fr)	1992-07-20	1994-10-14	Virbac	Vaccin antirabique avirulent.
US7074413B2 (en)	2000-03-23	2006-07-11	Thomas Jefferson University	Genetically engineered rabies recombinant vaccine for immunization of stray dogs and wildlife
EP1253197B1 (de) *	2001-04-23	2006-01-25	Akzo Nobel N.V.	Attenuierte Rekombinante Stabile Tollwutvirusmutanten und Lebendimpfstoffe
DE60231821D1 (de)	2001-10-10	2009-05-14	Univ Jefferson	Rekombinante tollwut-vakzine und verfahren zu ihrer herstellung und verwendung

2005
- 2005-07-12 RS RSP-2010/0334A patent/RS51371B/sr unknown
- 2005-07-12 WO PCT/US2005/024671 patent/WO2006017276A2/en not_active Ceased
- 2005-07-12 EP EP05790962A patent/EP1768697B1/de not_active Expired - Lifetime
- 2005-07-12 US US11/571,842 patent/US7695724B2/en not_active Expired - Lifetime
- 2005-07-12 DE DE602005021636T patent/DE602005021636D1/de not_active Expired - Lifetime
- 2005-07-12 MX MX2007000445A patent/MX2007000445A/es not_active Application Discontinuation
- 2005-07-12 CA CA002573631A patent/CA2573631A1/en not_active Abandoned
- 2005-07-12 AT AT05790962T patent/ATE469964T1/de not_active IP Right Cessation
2007
- 2007-01-11 ZA ZA200700323A patent/ZA200700323B/en unknown

Also Published As

Publication number	Publication date
DE602005021636D1 (de)	2010-07-15
US20080003657A1 (en)	2008-01-03
MX2007000445A (es)	2007-04-16
WO2006017276A3 (en)	2007-05-03
EP1768697A2 (de)	2007-04-04
ZA200700323B (en)	2008-05-28
US7695724B2 (en)	2010-04-13
EP1768697A4 (de)	2008-03-05
CA2573631A1 (en)	2006-02-16
EP1768697B1 (de)	2010-06-02
RS51371B (sr)	2011-02-28
WO2006017276A2 (en)	2006-02-16

Similar Documents

Publication	Publication Date	Title
Banerjee et al.	2020	Isolation, sequence, infectivity, and replication kinetics of severe acute respiratory syndrome coronavirus 2
ES2790887T3 (es)	2020-10-29	Medio de cultivo celular sin oligopéptidos
EP1768697A4 (de)	2008-03-05	Zusammensetzungen mit rekombinantem tollwutvirus
DK1098961T3 (da)	2008-05-26	Gensplejsede svækkede vira, der inducerer interferon
Koerner et al.	2012	Altered receptor specificity and fusion activity of the haemagglutinin contribute to high virulence of a mouse-adapted influenza A virus
FR11C0027I1 (fr)	2011-08-26	Virus de l'influenza recombinants pour vaccins et traitement genetique
BR0312173A (pt)	2005-04-05	Mólecula de cdna, molécula e sequência de cdna recombinante, vetor, processo de preparação de partìculas de vìrus do sarampo infeccioso, composição imunogênica, composição de vacina e vìrus mononegaviral recombinante
Shinohara et al.	1999	A highly pathogenic simian/human immunodeficiency virus with genetic changes in cynomolgus monkey
Chen et al.	2021	The novel PRRSV strain HBap4-2018 with a unique recombinant pattern is highly pathogenic to piglets
Zhang et al.	2013	Human astrocytic cells support persistent coxsackievirus B3 infection
DeHaven et al.	2011	The vaccinia virus A56 protein: a multifunctional transmembrane glycoprotein that anchors two secreted viral proteins
Chen et al.	2017	The whole genomic analysis of orf virus strain HN3/12 isolated from Henan province, central China
RU2008119438A (ru)	2009-11-27	Вирус собачьего гриппа, композиции, содержащие этот вирус, и способы их применения
Xu et al.	2020	A porcine alveolar macrophage cell line stably expressing CD163 demonstrates virus replication and cytokine secretion characteristics similar to primary alveolar macrophages following PRRSV infection
Walden et al.	1982	Intergenomic recombination events among pairs of defective cauliflower mosaic virus genomes in plants.
Gaska et al.	2015	Study of viral pathogenesis in humanized mice
Raheja et al.	2022	RG203KR mutations in SARS-CoV-2 nucleocapsid: assessing the impact using a virus-like particle model system
HUP0401585A2 (hu)	2004-11-29	Fertőző, marhában előforduló, vírusos hasmenés vírusklónja
Lee et al.	2005	Cysteine residues of the porcine reproductive and respiratory syndrome virus small envelope protein are non-essential for virus infectivity
Pei et al.	2019	Codon optimization of G protein enhances rabies virus-induced humoral immunity
BRPI0515450A (pt)	2008-07-29	produto refratário fundido e moldado de tipo azs e sua utilização
Hopkins et al.	1977	Evidence for recombination between N-and B-tropic murine leukemia viruses
Kanda et al.	2022	Exogenous expression of both matrix protein and glycoprotein facilitates infectious viral particle production of Borna disease virus 1
Liu et al.	2022	Enhancing half-life and cytotoxicity of porcine respiratory and reproductive syndrome virus soluble receptors by taming their Fc domains
ES2327217T3 (es)	2009-10-27	Cepa neurovirulenta del virus west-nile y sus aplicaciones.

Legal Events

Date	Code	Title	Description
2010-12-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties