ATE469985T1 - Verfahren zur untersuchung der empfindlichkeit einer krebszelle gegenüber einem antikrebsmittel - Google Patents
Verfahren zur untersuchung der empfindlichkeit einer krebszelle gegenüber einem antikrebsmittelInfo
- Publication number
- ATE469985T1 ATE469985T1 AT05710143T AT05710143T ATE469985T1 AT E469985 T1 ATE469985 T1 AT E469985T1 AT 05710143 T AT05710143 T AT 05710143T AT 05710143 T AT05710143 T AT 05710143T AT E469985 T1 ATE469985 T1 AT E469985T1
- Authority
- AT
- Austria
- Prior art keywords
- cancer cell
- sensitivity
- present compound
- cancer
- studying
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 9
- 201000011510 cancer Diseases 0.000 title abstract 9
- 230000035945 sensitivity Effects 0.000 title abstract 4
- 239000002246 antineoplastic agent Substances 0.000 title 1
- 229940041181 antineoplastic drug Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- 102000003909 Cyclin E Human genes 0.000 abstract 1
- 108090000257 Cyclin E Proteins 0.000 abstract 1
- 230000002411 adverse Effects 0.000 abstract 1
- 230000000259 anti-tumor effect Effects 0.000 abstract 1
- 238000001574 biopsy Methods 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5011—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Hematology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Cell Biology (AREA)
- General Engineering & Computer Science (AREA)
- Oncology (AREA)
- Hospice & Palliative Care (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004030106 | 2004-02-06 | ||
| JP2004069384 | 2004-03-11 | ||
| PCT/JP2005/002091 WO2005075681A1 (ja) | 2004-02-06 | 2005-02-04 | 抗癌剤に対する癌細胞の感受性を検定する方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE469985T1 true ATE469985T1 (de) | 2010-06-15 |
Family
ID=34840150
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05710143T ATE469985T1 (de) | 2004-02-06 | 2005-02-04 | Verfahren zur untersuchung der empfindlichkeit einer krebszelle gegenüber einem antikrebsmittel |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20080280288A1 (de) |
| EP (1) | EP1712642B1 (de) |
| AT (1) | ATE469985T1 (de) |
| DE (1) | DE602005021617D1 (de) |
| ES (1) | ES2343843T3 (de) |
| WO (1) | WO2005075681A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2008016187A1 (en) * | 2006-08-02 | 2008-02-07 | Eisai R & D Management Co., Ltd. | Pladienolide target molecule, compound capable of binding to the target molecule, and screening method for the compound |
| US7790887B2 (en) * | 2007-01-29 | 2010-09-07 | Eisai R&D Management Co., Ltd. | Macrolide compound in solid form, process for preparation thereof, and pharmaceutical composition containing the same |
| WO2008111464A1 (ja) * | 2007-03-05 | 2008-09-18 | Eisai R & D Management Co., Ltd. | スプライシング異常を指標とする抗ガン剤の作用検定方法 |
| JPWO2008111466A1 (ja) * | 2007-03-05 | 2010-06-24 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 遺伝子の発現量減少を指標とする抗ガン剤の作用検定方法 |
| JP2009092508A (ja) * | 2007-10-09 | 2009-04-30 | Norihiro Nishimoto | リウマチ治療剤の効果の予測方法 |
| CN103076453B (zh) * | 2012-12-24 | 2015-04-15 | 何以丰 | P16免疫细胞化学试剂盒及其制备用多肽序列 |
| CA3096400A1 (en) | 2018-04-09 | 2019-10-17 | Eisai R&D Management Co., Ltd. | Certain pladienolide compounds and methods of use |
| CA3096424A1 (en) | 2018-04-12 | 2019-10-17 | Eisai R&D Management Co., Ltd. | Pladienolide derivatives as spliceosome targeting agents for treating cancer |
| CN119405833A (zh) | 2018-06-01 | 2025-02-11 | 卫材R&D管理有限公司 | 剪接调节抗体-药物缀合物及其使用方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5897999A (en) * | 1996-03-22 | 1999-04-27 | The Johns Hopkins University | Cancer drug screen based on cell cycle uncoupling |
| AU2409602A (en) * | 2000-11-24 | 2002-06-03 | Eisai C0 Ltd | Method of testing anticancer agent-sensitivity of tumor cells |
| TWI312681B (en) * | 2001-02-01 | 2009-08-01 | Novel physiologically active substance | |
| TWI334866B (en) * | 2002-05-29 | 2010-12-21 | Mercian Corp | Novel physiologically active substances |
| RU2338741C2 (ru) * | 2002-07-31 | 2008-11-20 | Мершан Корпорейшн | Новые физиологически активные вещества |
-
2005
- 2005-02-04 AT AT05710143T patent/ATE469985T1/de not_active IP Right Cessation
- 2005-02-04 EP EP05710143A patent/EP1712642B1/de not_active Expired - Lifetime
- 2005-02-04 ES ES05710143T patent/ES2343843T3/es not_active Expired - Lifetime
- 2005-02-04 WO PCT/JP2005/002091 patent/WO2005075681A1/ja not_active Ceased
- 2005-02-04 US US10/586,536 patent/US20080280288A1/en not_active Abandoned
- 2005-02-04 DE DE602005021617T patent/DE602005021617D1/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP1712642A4 (de) | 2008-05-14 |
| ES2343843T3 (es) | 2010-08-11 |
| DE602005021617D1 (de) | 2010-07-15 |
| EP1712642B1 (de) | 2010-06-02 |
| US20080280288A1 (en) | 2008-11-13 |
| EP1712642A1 (de) | 2006-10-18 |
| WO2005075681A1 (ja) | 2005-08-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP1819227A4 (de) | Pharmazeutische formulierungen von decitabin | |
| Chesnokov et al. | Anti-cancer activity of glucosamine through inhibition of N-linked glycosylation | |
| CY1116610T1 (el) | Ετεροδιμερη γλουτamiνiκου οξεος | |
| TR200002796T2 (tr) | Aminosikloheksil eter bileşikleri ve bunların kullanımları. | |
| UA110347C2 (uk) | ПОХІДНІ 6-ЦИКЛОАЛКІЛ-1,5-ДИГІДРОПІРАЗОЛО[3,4-d]ПІРИМІДИН-4-ОНУ І ЇХ ЗАСТОСУВАННЯ ЯК ІНГІБІТОРІВ PDE9A | |
| EA201070929A1 (ru) | ФУРО- И ТИЕНО[3,2-c]ПИРИДИНЫ | |
| Bao et al. | Targeting CSCs within the tumor microenvironment for cancer therapy: a potential role of mesenchymal stem cells | |
| BRPI0510177B8 (pt) | composto, composição farmacêutica e uso do mesmo | |
| DE602005021617D1 (de) | Verfahren zur untersuchung der empfindlichkeit einer krebszelle gegenüber einem antikrebsmittel | |
| CY1109366T1 (el) | Υποκατεστημενες ενωσεις 1,4,8-τριαζασπειρο[4.5]δεκαν-2-ονης | |
| BR112022020500A2 (pt) | Corantes de cianina de infravermelho próximo e conjugados dos mesmos | |
| PE20110001A1 (es) | Derivados de taxanos como agentes citotoxicos | |
| MA29653B1 (fr) | Nouveaux composes analogues de la camptothecine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent | |
| Sandra et al. | Conditioned media of human umbilical cord blood mesenchymal stem cell-derived secretome induced apoptosis and inhibited growth of HeLa cells | |
| Narayanan et al. | Effects of bioactive compounds from marine algae on cancer-related inflammation: a review | |
| RU2013118021A (ru) | Способы и композиции для лечения сахарного диабета и дислипидемии | |
| EA200601846A1 (ru) | Содержащие бензоксазины лекарственные комбинации для лечения заболеваний дыхательных путей | |
| FR2903107B1 (fr) | Derives d'imidazopyridine-2-carboxamides, leur preparation et leur application en therapeutique | |
| DE602007006419D1 (de) | Verfahren zur verwendung von guava-extrakt und zusammensetzung mit guava-extrakt | |
| Rashan et al. | Molecular modes of action of an aqueous nerium oleander extract in cancer cells in vitro and in vivo | |
| CA2458318A1 (en) | Wortmannin analogs and methods of using same | |
| Ahn et al. | Amelioration of Particulate Matter-Induced Oxidative Stress by a Bioactive Hizikia fusiformis Extract: A Functional Biomaterial for Cosmeceutical Applications | |
| Samant et al. | The Ocean's Treasure Trove: Bioactive Compounds from Sea Sponges | |
| CN1871227A (zh) | 抗肿瘤剂 | |
| Akinlabi et al. | Contractile effect of Aqueous Pleurotus Tuberregium Extract on the isolated bovine iris |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |