ATE470722T1 - Strategien zur genexpressionsanalyse - Google Patents
Strategien zur genexpressionsanalyseInfo
- Publication number
- ATE470722T1 ATE470722T1 AT03765615T AT03765615T ATE470722T1 AT E470722 T1 ATE470722 T1 AT E470722T1 AT 03765615 T AT03765615 T AT 03765615T AT 03765615 T AT03765615 T AT 03765615T AT E470722 T1 ATE470722 T1 AT E470722T1
- Authority
- AT
- Austria
- Prior art keywords
- strategies
- gene expression
- expression analysis
- compound
- members
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/136—Screening for pharmacological compounds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/16—Primer sets for multiplex assays
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Biotechnology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39739302P | 2002-07-19 | 2002-07-19 | |
| PCT/US2003/022217 WO2004009765A2 (en) | 2002-07-19 | 2003-07-16 | Strategies for gene expression analysis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE470722T1 true ATE470722T1 (de) | 2010-06-15 |
Family
ID=30771049
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT03765615T ATE470722T1 (de) | 2002-07-19 | 2003-07-16 | Strategien zur genexpressionsanalyse |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7476519B2 (de) |
| EP (1) | EP1552010B1 (de) |
| AT (1) | ATE470722T1 (de) |
| AU (1) | AU2003261168A1 (de) |
| CA (1) | CA2491023A1 (de) |
| DE (1) | DE60332948D1 (de) |
| WO (1) | WO2004009765A2 (de) |
Families Citing this family (54)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2398107C (en) * | 2000-01-28 | 2013-11-19 | Althea Technologies, Inc. | Methods for analysis of gene expression |
| AU2004286201B2 (en) | 2003-09-10 | 2010-09-09 | Altheadx, Inc. | Expression profiling using microarrays |
| EP1721001A4 (de) * | 2004-02-04 | 2007-08-29 | Park Hee Kyung | Qualitätskontrollsonden umfassender mikroarray und verfahren zur herstellung davon |
| WO2005077125A2 (en) * | 2004-02-11 | 2005-08-25 | Applera Corporation | Methods and compositions for detecting nucleic acids |
| EP1591534A1 (de) * | 2004-04-01 | 2005-11-02 | Stichting Sanquin Bloedvoorziening | Verfahren zur Genotypisierung von Antigenen von Blutzellen und ein Kit zur Genotypisierung |
| EP1815021A2 (de) * | 2004-11-03 | 2007-08-08 | Almac Diagnostics Limited | Transkriptom-mikroarray-technologie und verfahren zu ihrer verwendung |
| AU2006243757B2 (en) * | 2005-05-03 | 2012-02-09 | Altheadx, Inc. | Compositions and methods for the analysis of degraded nucleic acids |
| EP1915461B1 (de) | 2005-08-17 | 2018-08-01 | Dx4U GmbH | Zusammensetzung und verfahren zur bestimmung der ck19-expression |
| AU2006287548A1 (en) * | 2005-09-06 | 2007-03-15 | Gen-Probe Incorporated | Methods, compositions and kits for isothermal amplification of nucleic acids |
| US20070092869A1 (en) * | 2005-10-24 | 2007-04-26 | Fulmer-Smentek Stephanie B | Spike-in controls and methods for using the same |
| CA2653321A1 (en) * | 2006-05-26 | 2007-12-06 | Althea Technologies, Inc. | Biochemical analysis of partitioned cells |
| EP3095873B1 (de) | 2006-12-21 | 2018-04-18 | Gen-Probe Incorporated | Verfahren und zusammensetzungen zur amplifizierung von nukleinsäuren |
| GB2453173A (en) * | 2007-09-28 | 2009-04-01 | Dxs Ltd | Polynucleotide primers |
| US9551026B2 (en) | 2007-12-03 | 2017-01-24 | Complete Genomincs, Inc. | Method for nucleic acid detection using voltage enhancement |
| WO2009086353A1 (en) * | 2007-12-26 | 2009-07-09 | Helicos Biosciences Corporation | Improved two-primer sequencing for high-throughput expression analysis |
| AU2009244634B2 (en) * | 2008-04-16 | 2014-12-18 | iRepertoire, Inc. | Method for evaluating and comparing immunorepertoires |
| EP2319014B1 (de) * | 2008-07-15 | 2015-04-29 | Institut Pasteur Korea | Verfahren und vorrichtung zum abbilden von merkmalen auf einem substrat |
| US9528160B2 (en) | 2008-11-07 | 2016-12-27 | Adaptive Biotechnolgies Corp. | Rare clonotypes and uses thereof |
| US8691510B2 (en) | 2008-11-07 | 2014-04-08 | Sequenta, Inc. | Sequence analysis of complex amplicons |
| US8628927B2 (en) | 2008-11-07 | 2014-01-14 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| EP2364368B1 (de) | 2008-11-07 | 2014-01-15 | Sequenta, Inc. | Verfahren zur überwachung von krankheitszuständen mittels sequenzanalyse |
| US9365901B2 (en) | 2008-11-07 | 2016-06-14 | Adaptive Biotechnologies Corp. | Monitoring immunoglobulin heavy chain evolution in B-cell acute lymphoblastic leukemia |
| US8748103B2 (en) | 2008-11-07 | 2014-06-10 | Sequenta, Inc. | Monitoring health and disease status using clonotype profiles |
| US9506119B2 (en) | 2008-11-07 | 2016-11-29 | Adaptive Biotechnologies Corp. | Method of sequence determination using sequence tags |
| ES2726702T3 (es) | 2009-01-15 | 2019-10-08 | Adaptive Biotechnologies Corp | Perfilado de la inmunidad adaptativa y métodos para la generación de anticuerpos monoclonales |
| WO2010135669A1 (en) * | 2009-05-22 | 2010-11-25 | Sabiosciences Corporation | Arrays and methods for reverse genetic functional analysis |
| WO2010151416A1 (en) | 2009-06-25 | 2010-12-29 | Fred Hutchinson Cancer Research Center | Method of measuring adaptive immunity |
| US8512955B2 (en) | 2009-07-01 | 2013-08-20 | Gen-Probe Incorporated | Methods and compositions for nucleic acid amplification |
| JP2011086142A (ja) * | 2009-10-16 | 2011-04-28 | Ricoh Co Ltd | 画像形成装置及びプログラム操作方法 |
| US9043160B1 (en) | 2009-11-09 | 2015-05-26 | Sequenta, Inc. | Method of determining clonotypes and clonotype profiles |
| US10385475B2 (en) | 2011-09-12 | 2019-08-20 | Adaptive Biotechnologies Corp. | Random array sequencing of low-complexity libraries |
| EP2768982A4 (de) | 2011-10-21 | 2015-06-03 | Adaptive Biotechnologies Corp | Quantifizierung von adaptiven immunzellgenomen in einer komplexen mischung von zellen |
| US10837879B2 (en) | 2011-11-02 | 2020-11-17 | Complete Genomics, Inc. | Treatment for stabilizing nucleic acid arrays |
| US9824179B2 (en) | 2011-12-09 | 2017-11-21 | Adaptive Biotechnologies Corp. | Diagnosis of lymphoid malignancies and minimal residual disease detection |
| US9499865B2 (en) | 2011-12-13 | 2016-11-22 | Adaptive Biotechnologies Corp. | Detection and measurement of tissue-infiltrating lymphocytes |
| CA2859021A1 (en) | 2011-12-19 | 2013-06-27 | Valley Health System | Methods and kits for detecting subjects at risk of having cancer |
| EP3372694A1 (de) | 2012-03-05 | 2018-09-12 | Adaptive Biotechnologies Corporation | Festlegung von gepaarten immunrezeptorketten aus frequenzabgestimmten untereinheiten |
| HUE029357T2 (en) | 2012-05-08 | 2017-02-28 | Adaptive Biotechnologies Corp | Preparations and devices for measuring and calibrating amplification distortion in multiplex PCR reactions |
| AU2013302861A1 (en) | 2012-08-13 | 2015-03-05 | The Rockefeller University | Treatment and diagnosis of melanoma |
| EP3330384B1 (de) | 2012-10-01 | 2019-09-25 | Adaptive Biotechnologies Corporation | Immunkompetenzbeurteilung durch adaptive immunrezeptordiversität und klonalitätscharakterisierung |
| WO2015160439A2 (en) | 2014-04-17 | 2015-10-22 | Adaptive Biotechnologies Corporation | Quantification of adaptive immune cell genomes in a complex mixture of cells |
| WO2014071067A2 (en) | 2012-10-31 | 2014-05-08 | The Rockefeller University | Treatment and diagnosis of colon cancer |
| US9708657B2 (en) | 2013-07-01 | 2017-07-18 | Adaptive Biotechnologies Corp. | Method for generating clonotype profiles using sequence tags |
| WO2015134787A2 (en) | 2014-03-05 | 2015-09-11 | Adaptive Biotechnologies Corporation | Methods using randomer-containing synthetic molecules |
| US10066265B2 (en) | 2014-04-01 | 2018-09-04 | Adaptive Biotechnologies Corp. | Determining antigen-specific t-cells |
| CA2966201A1 (en) | 2014-10-29 | 2016-05-06 | Adaptive Biotechnologies Corp. | Highly-multiplexed simultaneous detection of nucleic acids encoding paired adaptive immune receptor heterodimers from many samples |
| US10246701B2 (en) | 2014-11-14 | 2019-04-02 | Adaptive Biotechnologies Corp. | Multiplexed digital quantitation of rearranged lymphoid receptors in a complex mixture |
| AU2015353581A1 (en) | 2014-11-25 | 2017-06-15 | Adaptive Biotechnologies Corporation | Characterization of adaptive immune response to vaccination or infection using immune repertoire sequencing |
| CA2976580A1 (en) | 2015-02-24 | 2016-09-01 | Adaptive Biotechnologies Corp. | Methods for diagnosing infectious disease and determining hla status using immune repertoire sequencing |
| EP3277294B1 (de) | 2015-04-01 | 2024-05-15 | Adaptive Biotechnologies Corp. | Verfahren zur identifizierung von menschlichen kompatiblen t-zell-rezeptoren spezifisch für ein antigen-ziel |
| US10428325B1 (en) | 2016-09-21 | 2019-10-01 | Adaptive Biotechnologies Corporation | Identification of antigen-specific B cell receptors |
| CA3078981A1 (en) | 2017-11-21 | 2019-05-31 | Rgenix, Inc. | Polymorphs and uses thereof |
| US11254980B1 (en) | 2017-11-29 | 2022-02-22 | Adaptive Biotechnologies Corporation | Methods of profiling targeted polynucleotides while mitigating sequencing depth requirements |
| TWI888447B (zh) | 2019-12-13 | 2025-07-01 | 美商因思博納公司 | 金屬鹽及其用途 |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5143854A (en) | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| US6040138A (en) * | 1995-09-15 | 2000-03-21 | Affymetrix, Inc. | Expression monitoring by hybridization to high density oligonucleotide arrays |
| EP0484440A4 (en) | 1989-07-28 | 1993-01-07 | Us Health | Efficient directional genetic cloning system |
| US5545522A (en) | 1989-09-22 | 1996-08-13 | Van Gelder; Russell N. | Process for amplifying a target polynucleotide sequence using a single primer-promoter complex |
| US5807522A (en) | 1994-06-17 | 1998-09-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods for fabricating microarrays of biological samples |
| WO1997027317A1 (en) | 1996-01-23 | 1997-07-31 | Affymetrix, Inc. | Nucleic acid analysis techniques |
| US5882856A (en) * | 1995-06-07 | 1999-03-16 | Genzyme Corporation | Universal primer sequence for multiplex DNA amplification |
| US5962271A (en) | 1996-01-03 | 1999-10-05 | Cloutech Laboratories, Inc. | Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end |
| US6072043A (en) * | 1996-06-04 | 2000-06-06 | Polyprobe, Inc. | Optimally fluorescent oligonucleotides |
| US5922617A (en) * | 1997-11-12 | 1999-07-13 | Functional Genetics, Inc. | Rapid screening assay methods and devices |
| CA2310621A1 (en) | 1997-11-20 | 1999-06-03 | Smithkline Beecham Corporation | Methods for identifying the toxic/pathologic effect of environmental stimuli on gene transcription |
| US6087102A (en) | 1998-01-07 | 2000-07-11 | Clontech Laboratories, Inc. | Polymeric arrays and methods for their use in binding assays |
| US6500938B1 (en) | 1998-01-30 | 2002-12-31 | Incyte Genomics, Inc. | Composition for the detection of signaling pathway gene expression |
| US6458566B2 (en) | 1998-10-23 | 2002-10-01 | Albert Einstein College Of Medicine Of Yeshiva University | Method of identification of differentially expressed MRNA |
| US6429027B1 (en) * | 1998-12-28 | 2002-08-06 | Illumina, Inc. | Composite arrays utilizing microspheres |
| DK1218542T3 (da) | 1999-09-13 | 2004-08-02 | Nugen Technologies Inc | Fremgangsmåder og sammensætninger til lineær isotermisk amplifikation af polynukleotidsekvenser |
| US6406840B1 (en) * | 1999-12-17 | 2002-06-18 | Biomosaic Systems, Inc. | Cell arrays and the uses thereof |
| WO2001051667A2 (en) * | 2000-01-14 | 2001-07-19 | Integriderm, L.L.C. | Informative nucleic acid arrays and methods for making same |
| CA2398107C (en) * | 2000-01-28 | 2013-11-19 | Althea Technologies, Inc. | Methods for analysis of gene expression |
| AU2001278987A1 (en) | 2000-07-21 | 2002-02-05 | Althea Technologies, Inc. | A systematic approach to mechanism-of-response analyses |
| US7198895B2 (en) * | 2000-11-14 | 2007-04-03 | Mohanlal Ramon W | In vitro cell-based methods for biological validation and pharmacological screening of chemical entities and biologicals |
-
2003
- 2003-07-16 AT AT03765615T patent/ATE470722T1/de not_active IP Right Cessation
- 2003-07-16 EP EP03765615A patent/EP1552010B1/de not_active Expired - Lifetime
- 2003-07-16 DE DE60332948T patent/DE60332948D1/de not_active Expired - Lifetime
- 2003-07-16 CA CA002491023A patent/CA2491023A1/en not_active Abandoned
- 2003-07-16 AU AU2003261168A patent/AU2003261168A1/en not_active Abandoned
- 2003-07-16 US US10/622,010 patent/US7476519B2/en not_active Expired - Fee Related
- 2003-07-16 WO PCT/US2003/022217 patent/WO2004009765A2/en not_active Ceased
-
2008
- 2008-11-26 US US12/315,115 patent/US7897750B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE60332948D1 (de) | 2010-07-22 |
| US20090149346A1 (en) | 2009-06-11 |
| EP1552010A2 (de) | 2005-07-13 |
| US7897750B2 (en) | 2011-03-01 |
| AU2003261168A1 (en) | 2004-02-09 |
| EP1552010B1 (de) | 2010-06-09 |
| WO2004009765A2 (en) | 2004-01-29 |
| EP1552010A4 (de) | 2007-03-14 |
| US20040132050A1 (en) | 2004-07-08 |
| CA2491023A1 (en) | 2004-01-29 |
| AU2003261168A8 (en) | 2004-02-09 |
| US7476519B2 (en) | 2009-01-13 |
| WO2004009765A3 (en) | 2004-12-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |