ATE471516T1 - Sensorvorrichtung und verfahren zum detektieren magnetischer partikel - Google Patents

Sensorvorrichtung und verfahren zum detektieren magnetischer partikel

Info

Publication number
ATE471516T1
ATE471516T1 AT07805038T AT07805038T ATE471516T1 AT E471516 T1 ATE471516 T1 AT E471516T1 AT 07805038 T AT07805038 T AT 07805038T AT 07805038 T AT07805038 T AT 07805038T AT E471516 T1 ATE471516 T1 AT E471516T1
Authority
AT
Austria
Prior art keywords
sensor device
magnetic particles
detecting magnetic
substrate
magnetic field
Prior art date
Application number
AT07805038T
Other languages
English (en)
Inventor
Lankvelt Petrus Johannes Wilhelmu Van
Jeroen Hans Nieuwenhuis
Albert Hendrik Jan Immink
Josephus Arnoldus Henricus Ma Kahlman
Original Assignee
Koninkl Philips Electronics Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Koninkl Philips Electronics Nv filed Critical Koninkl Philips Electronics Nv
Application granted granted Critical
Publication of ATE471516T1 publication Critical patent/ATE471516T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y25/00—Nanomagnetism, e.g. magnetoimpedance, anisotropic magnetoresistance, giant magnetoresistance or tunneling magnetoresistance
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/06—Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
    • G01R33/07—Hall effect devices
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
    • G01R33/06—Measuring direction or magnitude of magnetic fields or magnetic flux using galvano-magnetic devices
    • G01R33/09—Magnetoresistive devices
    • G01R33/093—Magnetoresistive devices using multilayer structures, e.g. giant magnetoresistance sensors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1269—Measuring magnetic properties of articles or specimens of solids or fluids of molecules labeled with magnetic beads
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
    • G01R33/00—Arrangements or instruments for measuring magnetic variables
    • G01R33/12—Measuring magnetic properties of articles or specimens of solids or fluids
    • G01R33/1276—Measuring magnetic properties of articles or specimens of solids or fluids of magnetic particles, e.g. imaging of magnetic nanoparticles

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Nanotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Electrochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
AT07805038T 2007-02-23 2007-06-25 Sensorvorrichtung und verfahren zum detektieren magnetischer partikel ATE471516T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP07102984 2007-02-23
PCT/IB2007/052449 WO2008102218A1 (en) 2007-02-23 2007-06-25 A sensor device for and a method of sensing magnetic particles

Publications (1)

Publication Number Publication Date
ATE471516T1 true ATE471516T1 (de) 2010-07-15

Family

ID=39046597

Family Applications (1)

Application Number Title Priority Date Filing Date
AT07805038T ATE471516T1 (de) 2007-02-23 2007-06-25 Sensorvorrichtung und verfahren zum detektieren magnetischer partikel

Country Status (7)

Country Link
US (1) US8190372B2 (de)
EP (1) EP2115468B1 (de)
JP (1) JP2010530956A (de)
CN (1) CN101632018B (de)
AT (1) ATE471516T1 (de)
DE (1) DE602007007243D1 (de)
WO (1) WO2008102218A1 (de)

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CN102187241B (zh) * 2008-10-17 2015-11-25 皇家飞利浦电子股份有限公司 用于灵敏测定的脉冲磁激励
RU2011121883A (ru) * 2008-10-31 2012-12-10 Конинклейке Филипс Электроникс Н.В. Биосенсор с многокамерным контейнером
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DE102009012108B4 (de) 2009-03-06 2015-07-16 Siemens Aktiengesellschaft Vorrichtung und Verfahren zur Anreicherung und Erfassung von Zellen in strömenden Medien
WO2011161499A1 (en) * 2010-06-22 2011-12-29 Koninklijke Philips Electronics N.V. Detection of magnetic particles and their clustering
FR2962221A1 (fr) * 2010-07-02 2012-01-06 Biofilm Control Procede de detection d'interactions moleculaires
EP2614365B1 (de) 2010-09-09 2019-02-20 Koninklijke Philips N.V. Verfahren und vorrichtung zur anziehung von magnetpartikeln an eine oberfläche
CN103229056B (zh) * 2010-11-30 2015-06-24 皇家飞利浦电子股份有限公司 用于磁致动粒子的传感器装置
US9304130B2 (en) 2010-12-16 2016-04-05 International Business Machines Corporation Trenched sample assembly for detection of analytes with electromagnetic read-write heads
US9040311B2 (en) 2011-05-03 2015-05-26 International Business Machines Corporation Calibration assembly for aide in detection of analytes with electromagnetic read-write heads
US8855957B2 (en) 2011-05-03 2014-10-07 International Business Machines Corporation Method for calibrating read sensors of electromagnetic read-write heads
EP2541230A1 (de) 2011-06-30 2013-01-02 Koninklijke Philips Electronics N.V. Erkennung von Clustern aus magnetischen Partikeln
US9863863B2 (en) 2011-11-14 2018-01-09 Koninklijke Philips N.V. Apparatus for cluster detection
JP5746643B2 (ja) * 2012-01-23 2015-07-08 株式会社東芝 測定システム、および測定方法
TWI540322B (zh) * 2012-09-08 2016-07-01 西凱渥資訊處理科技公司 關於近場電磁探針及掃描器之系統，裝置及方法
US9435800B2 (en) 2012-09-14 2016-09-06 International Business Machines Corporation Sample assembly with an electromagnetic field to accelerate the bonding of target antigens and nanoparticles
US20140271364A1 (en) * 2013-03-15 2014-09-18 National Taiwan University Electro-immuno sensing device
DE102013219114A1 (de) * 2013-09-24 2015-04-09 Siemens Aktiengesellschaft Multiplexverfahren für eine magnetische Durchflusszytometrie
US20160011182A1 (en) * 2014-07-09 2016-01-14 Zepto Life Technology, LLC Method and system for substance detection with a magnetic sensor
JP6788586B2 (ja) 2014-11-19 2020-11-25 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． Ｈｎｌを用いる診断方法
JP6637077B2 (ja) * 2015-06-12 2020-01-29 コーニンクレッカ フィリップス エヌ ヴェＫｏｎｉｎｋｌｉｊｋｅ Ｐｈｉｌｉｐｓ Ｎ．Ｖ． 光学式粒子センサとセンシング方法
US9702748B2 (en) * 2015-10-14 2017-07-11 International Business Machines Corporation Graphene-based magnetic hall sensor for fluid flow analysis at nanoscale level
US10145906B2 (en) 2015-12-17 2018-12-04 Analog Devices Global Devices, systems and methods including magnetic structures
US10976255B2 (en) 2016-04-28 2021-04-13 National Institute Of Advanced Industrial Science And Technology Optical detection method and optical detection device
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CN107045111B (zh) * 2017-03-29 2023-10-13 金华职业技术学院 一种用于测量磁性分子团簇的磁矩的磁强计
US12241851B2 (en) 2018-07-27 2025-03-04 Zepto Life Technology, Inc. System and method for processing analyte signals in GMR-based detection of biomarkers
CN108932623B (zh) * 2018-09-04 2020-09-22 深圳砺剑脑科学科技有限公司 一种智能防伪系统
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JP7455529B2 (ja) 2019-08-01 2024-03-26 キヤノンメディカルシステムズ株式会社 検体測定装置及び検体測定装置の制御方法
US12600825B2 (en) 2020-01-08 2026-04-14 Zepto Life Technology, Inc. Polymer compositions and biosurfaces comprising them on sensors
EP4090987A4 (de) 2020-01-17 2024-01-17 Zepto Life Technology, LLC Systeme und verfahren zum messen von analyten in der gmr-basierten detektion von biomarkern
EP3904897A1 (de) * 2020-04-29 2021-11-03 Technische Universität München Parallelisierte magnetische erfassung von proben unter verwendung von festkörper-spinsystemen
CN116391126A (zh) 2020-08-07 2023-07-04 维塔生物科技公司 磁性分析物检测的动力学调节
US12269484B2 (en) 2021-02-26 2025-04-08 NearField Atomics Inc. Systems and methods to keep drivers, pilots, or others alert or focused by electromagnetic delivery of signals
ES3034407T3 (en) 2021-03-22 2025-08-18 Nearfield Atomics Inc Systems and methods for measuring magnetic fields from solvated target molecules using a magnetoresistive sensor
WO2023046901A1 (en) 2021-09-24 2023-03-30 Analog Devices International Unlimited Company, Magnetic field sensing based on particle position within container
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Also Published As

Publication number Publication date
WO2008102218A1 (en) 2008-08-28
DE602007007243D1 (de) 2010-07-29
JP2010530956A (ja) 2010-09-16
EP2115468B1 (de) 2010-06-16
US8190372B2 (en) 2012-05-29
CN101632018A (zh) 2010-01-20
CN101632018B (zh) 2017-12-08
EP2115468A1 (de) 2009-11-11
US20100324828A1 (en) 2010-12-23

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