ATE473009T1 - Hemmung der neurodegeneration - Google Patents

Hemmung der neurodegeneration

Info

Publication number
ATE473009T1
ATE473009T1 AT02739383T AT02739383T ATE473009T1 AT E473009 T1 ATE473009 T1 AT E473009T1 AT 02739383 T AT02739383 T AT 02739383T AT 02739383 T AT02739383 T AT 02739383T AT E473009 T1 ATE473009 T1 AT E473009T1
Authority
AT
Austria
Prior art keywords
disease
inhibiting neurodegeneration
alzheimer
inhibiting
neurodegeneration
Prior art date
Application number
AT02739383T
Other languages
English (en)
Inventor
Jack Wands
La Monte Suzanne De
Original Assignee
Rhode Island Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhode Island Hospital filed Critical Rhode Island Hospital
Application granted granted Critical
Publication of ATE473009T1 publication Critical patent/ATE473009T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4711—Alzheimer's disease; Amyloid plaque core protein
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0275—Genetically modified vertebrates, e.g. transgenic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/67—General methods for enhancing the expression
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/0306—Animal model for genetic diseases
    • A01K2267/0312—Animal model for Alzheimer's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Environmental Sciences (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Neurology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Neurosurgery (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Animal Husbandry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
AT02739383T 2001-06-01 2002-05-28 Hemmung der neurodegeneration ATE473009T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/872,968 US6770797B2 (en) 2001-06-01 2001-06-01 Non-Transgenic nonhuman model for Alzheimer's Disease using a AD7c-NTP nucleic acid
PCT/US2002/016429 WO2002099036A2 (en) 2001-06-01 2002-05-28 Inhibition of neurodegeneration

Publications (1)

Publication Number Publication Date
ATE473009T1 true ATE473009T1 (de) 2010-07-15

Family

ID=25360708

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02739383T ATE473009T1 (de) 2001-06-01 2002-05-28 Hemmung der neurodegeneration

Country Status (8)

Country Link
US (2) US6770797B2 (de)
EP (1) EP1414478B1 (de)
JP (1) JP2005516886A (de)
AT (1) ATE473009T1 (de)
AU (1) AU2002312033B2 (de)
CA (1) CA2448863C (de)
DE (1) DE60236939D1 (de)
WO (1) WO2002099036A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20040029968A (ko) * 2001-05-04 2004-04-08 니목스 코포레이션 신경 사 단백질에 대한 항체를 사용하여 세포 사멸을억제하는 방법
JP2005535580A (ja) * 2002-04-26 2005-11-24 イアン， エイ． ファーガソン， 血液脳関門を通したポリペプチドの非侵襲的な送達およびエンドサイトーシスリガンドの生体内選択
AU2003233120B2 (en) * 2002-04-26 2008-08-21 Ferguson, Ian Andrew Non-invasive delivery of polypeptides through the blood-brain barrier, and in vivo selection of endocytotic ligands
US7544771B2 (en) * 2005-02-23 2009-06-09 Nymox Corporation Protein and its use in diagnosing Alzheimer's disease
WO2010075511A1 (en) * 2008-12-23 2010-07-01 Salk Institute For Biological Studies Method of treating neurodegenerative disease
US9128094B2 (en) * 2010-01-08 2015-09-08 Oncohealth Corp. High throughput cell-based HPV immunoassays for diagnosis and screening of HPV-associated cancers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5948634A (en) * 1988-12-21 1999-09-07 The General Hospital Coporation Neural thread protein gene expression and detection of alzheimer's disease
US5800390A (en) * 1991-05-24 1998-09-01 Sumitomo Pharmaceuticals Company, Limited Equipment for intracerebral administration of preparations
KR100392244B1 (ko) 1993-04-20 2003-11-28 더 제너럴 호스피탈 코포레이션 신경사단백질유전자발현및알쯔하이머병의검출
US5744335A (en) * 1995-09-19 1998-04-28 Mirus Corporation Process of transfecting a cell with a polynucleotide mixed with an amphipathic compound and a DNA-binding protein
US5863898A (en) * 1996-10-29 1999-01-26 Incyte Pharmaceuticals, Inc. Human lim proteins
JP3758792B2 (ja) * 1997-02-25 2006-03-22 三菱重工業株式会社 ガスタービン動翼のプラットフォーム冷却機構
EP0975651A4 (de) 1997-02-26 2005-03-09 Gen Hospital Corp Transgene tiere und zellinien zur erkennung von zur behandlung oder vorbeugung der alzheimerschen krankheit wirksamen medikamente
JP2001514663A (ja) 1997-03-12 2001-09-11 エスモンド，ロバート ダブリュー． アルツハイマー病を処置または予防するための方法

Also Published As

Publication number Publication date
JP2005516886A (ja) 2005-06-09
WO2002099036A2 (en) 2002-12-12
US20050090441A1 (en) 2005-04-28
US7319094B2 (en) 2008-01-15
AU2002312033B2 (en) 2007-10-18
CA2448863C (en) 2010-05-04
WO2002099036A3 (en) 2004-01-08
US6770797B2 (en) 2004-08-03
EP1414478A4 (de) 2007-03-21
US20030050262A1 (en) 2003-03-13
DE60236939D1 (de) 2010-08-19
EP1414478A2 (de) 2004-05-06
CA2448863A1 (en) 2002-12-12
EP1414478B1 (de) 2010-07-07

Similar Documents

Publication Publication Date Title
EP1319408A4 (de) Arzneimittel für herzversagen
MY130489A (en) Substituted aryl 1, 4-pyrazine derivatives
DE60234269D1 (de) Substituierte aryl 1,4-pyrazin derivate
EP1697308A4 (de) Phenylamid- und pyridylamid-beta-sekretase-inhibitoren zur behandlung von alzheimer-krankheit
AP2004003026A0 (en) Methods for treating ocular neovascular diseases.
DE69924387D1 (de) Nicht-peptidische gnrh agentia, verfahren und zwischenverbindungen zur ihren herstellung
WO2006138659A3 (en) Intranasal red light probe for treating alzheimers disease
WO2005004814A3 (en) Sirt1 and genetic disorders
PL1765388T3 (pl) Terapia skojarzona do zapobiegania chorobie Alzheimera lub leczenia tej choroby oraz zestaw do tego celu
EA200300027A1 (ru) Способ лечения сердечно-сосудистых заболеваний
WO2001058476A3 (en) Methods and compositions for treatment of alzheimer's disease by enhancing plasmin or plasmin-like activity
IT1319834B1 (it) Procedimento per la produzione di getti in lega leggera.
ATE473009T1 (de) Hemmung der neurodegeneration
AU2002356998A8 (en) Genetic markers associated with desirable and undesirable traits in horses, methods of identifying and using such markers
WO2004006856A3 (en) Iron sequestration or elimination to reduce neurodegeneration or parkinsons disease progression
WO2002004677A8 (en) Methods for diagnosis and treatment of psychiatric disorders
DE60323034D1 (de) Form zur Herstellung von Modell und Modell zum Feingiessen
AU2001262726A1 (en) Transgenic non-human mammal and method of constructing the same, animal disease model and method of clarifying gene function
TW200503717A (en) Substituted 1,4-pyrazine derivatives
AR028316A1 (es) Gen de masa nsea elevada del cromosoma 11q13.3
WO2002027034A3 (en) Method of identifying genetic regions associated with disease and predicting responsiveness to therapeutic agents
SI1292187T1 (sl) Transgenski zivalski model nevrodegenerativnih motenj
DK1670309T3 (da) Transgenetiske dyr med større lidelser i forbindelse med Alzheimers sygdom
DE60133563D1 (de) Külen
ITVR20020071A1 (it) Procedimento ed attrezzatura per l'appassimento dell'uva.

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties