ATE473019T1 - Stabilisierung von wässerigen zusammensetzungen von 18f-markiertem 2-fluoro-2-deoxy-d-glukose mit ethanol - Google Patents

Stabilisierung von wässerigen zusammensetzungen von 18f-markiertem 2-fluoro-2-deoxy-d-glukose mit ethanol

Info

Publication number
ATE473019T1
ATE473019T1 AT02773830T AT02773830T ATE473019T1 AT E473019 T1 ATE473019 T1 AT E473019T1 AT 02773830 T AT02773830 T AT 02773830T AT 02773830 T AT02773830 T AT 02773830T AT E473019 T1 ATE473019 T1 AT E473019T1
Authority
AT
Austria
Prior art keywords
ethanol
labeled
deoxy
fluoro
stabilization
Prior art date
Application number
AT02773830T
Other languages
English (en)
Inventor
Maxim Y Kiselev
Vincent Tadino
Original Assignee
Ion Beam Applic Sa
Maxim Y Kiselev
Vincent Tadino
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=32311616&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE473019(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Ion Beam Applic Sa, Maxim Y Kiselev, Vincent Tadino filed Critical Ion Beam Applic Sa
Application granted granted Critical
Publication of ATE473019T1 publication Critical patent/ATE473019T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0491—Sugars, nucleosides, nucleotides, oligonucleotides, nucleic acids, e.g. DNA, RNA, nucleic acid aptamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
AT02773830T 2002-11-05 2002-11-05 Stabilisierung von wässerigen zusammensetzungen von 18f-markiertem 2-fluoro-2-deoxy-d-glukose mit ethanol ATE473019T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2002/033616 WO2004043497A1 (en) 2002-11-05 2002-11-05 Stabilzation of radiopharmceuticals labeled with 18-f

Publications (1)

Publication Number Publication Date
ATE473019T1 true ATE473019T1 (de) 2010-07-15

Family

ID=32311616

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02773830T ATE473019T1 (de) 2002-11-05 2002-11-05 Stabilisierung von wässerigen zusammensetzungen von 18f-markiertem 2-fluoro-2-deoxy-d-glukose mit ethanol

Country Status (10)

Country Link
EP (2) EP2229957A3 (de)
JP (1) JP2006505610A (de)
KR (1) KR101001300B1 (de)
CN (1) CN100478035C (de)
AT (1) ATE473019T1 (de)
AU (1) AU2002337926B8 (de)
BR (1) BR0215913A (de)
DE (1) DE60236971D1 (de)
ES (1) ES2347535T3 (de)
WO (1) WO2004043497A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100563812C (zh) * 2006-03-22 2009-12-02 上海化工研究院 一种可制备多种氟标试剂的化学合成装置
JP5238496B2 (ja) 2006-05-19 2013-07-17 日本メジフィジックス株式会社 新規アミロイド親和性化合物
CN101501033B (zh) 2006-06-21 2012-08-01 通用电气医疗有限公司 对淀粉状蛋白具有亲和性的化合物
US8496910B2 (en) 2006-06-21 2013-07-30 Ge Healthcare As Stabilisation of radiopharmaceutical precursors
CN101595108A (zh) 2006-11-30 2009-12-02 日本医事物理股份有限公司 对淀粉状蛋白具有亲和性的新化合物
US8790620B2 (en) 2006-12-21 2014-07-29 Nihon Medi-Physics Co., Ltd. Radioactive diagnostic imaging agent
EP2119458B9 (de) 2007-02-13 2013-08-21 Nihon Medi-Physics Co., Ltd. Verfahren zur herstellung eines abbildungsmittels zur strahlendiagnose
EP2214722A1 (de) * 2007-11-07 2010-08-11 GE Healthcare BV Stabilisierung von radiopharmaka
CA2801530C (en) 2010-06-04 2017-09-12 Piramal Imaging Sa Method for production of f-18 labeled amyloid beta ligands
WO2012021882A2 (en) 2010-08-13 2012-02-16 Siemens Medical Solutions Usa, Inc. Formulation, apparatus and method for stabilizing radiopharmaceuticals
KR20130132892A (ko) 2010-12-29 2013-12-05 지이 헬쓰케어 리미티드 용리제 용액
JP6446268B2 (ja) 2011-12-21 2018-12-26 ジーイー・ヘルスケア・リミテッド クエン酸緩衝液中の１８ｆ−フルシクロビン組成物
GB201322456D0 (en) * 2013-12-18 2014-02-05 Ge Healthcare Ltd Radiotracer compositions and methods
KR101668724B1 (ko) 2014-05-30 2016-10-24 성균관대학교산학협력단 방사성 화합물 합성모듈
KR101633250B1 (ko) 2014-05-30 2016-06-24 성균관대학교산학협력단 방사성 화합물 합성장치
KR101642091B1 (ko) 2014-05-30 2016-07-22 성균관대학교산학협력단 방사성 화합물 합성장치 및 합성방법
WO2017014599A1 (ko) * 2015-07-22 2017-01-26 주식회사 씨코헬스케어 [18f]플루오로-도파의 방사화학적 순도를 안정화시키는 조성물 및 이의 제조방법
CN107198780A (zh) * 2016-03-18 2017-09-26 南京江原安迪科正电子研究发展有限公司 放射性药物组合物及其制备方法、应用
GB202005282D0 (en) 2020-04-09 2020-05-27 Blue Earth Diagnostics Ltd Pharmaceutical Formulations

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Publication number Priority date Publication date Assignee Title
MC2260A1 (fr) 1990-06-18 1993-04-26 Dow Chemical Co Formulations de produits radiopharmaceutiques,leur methode d'administration et leur procede de preparation
DE69231469T2 (de) 1991-08-29 2001-01-25 Mallinckrodt Medical, Inc. Verwendung von gentisinsäure oder gentisylalkohol zur stabilisierung von radio-markierten peptiden und proteinen
US6066309A (en) 1996-02-02 2000-05-23 Rhomed Incorporated Post-labeling stabilization of radiolabeled proteins and peptides
JP3133250B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 使い捨てカートリッジを使用するｆｄｇ合成装置
JP3279914B2 (ja) * 1996-03-29 2002-04-30 エヌケ−ケ−プラント建設株式会社 オンカラムｆｄｇ合成装置
US5932178A (en) * 1996-03-29 1999-08-03 Nkk Plant Engineering Corporation FDG synthesizer using columns
JP3133252B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 三方切り替え活栓を組み込んだｆｄｇ合成装置
JP3133251B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 陽イオン交換樹脂カラム上で、溶媒除去と加水分解反応を同時に行うｆｄｇ合成装置
JP3133253B2 (ja) * 1996-03-29 2001-02-05 エヌケ−ケ−プラント建設株式会社 標識反応および加水分解反応をカラムで行うｆｄｇ合成装置
US6027710A (en) 1996-09-18 2000-02-22 Nihon Medi-Physiscs Co., Ltd. Radiation-protecting agent
WO2001082864A2 (en) * 2000-04-28 2001-11-08 Duke University 18f-labeled choline analogs
WO2002004030A2 (en) * 2000-07-06 2002-01-17 Bristol-Myers Squibb Pharma Company Stable radiopharmaceutical compositions
CN2468490Y (zh) * 2000-09-25 2002-01-02 杜宜奎 氟－18标记药物生产装置
EP1377321A4 (de) 2001-02-23 2006-01-11 Bristol Myers Squibb Co Markierte makrophagen-scavenger-rezeptor- antagonisten zur bilddarstellung der atherosklerose und von empfänglichem plaque
GB0115927D0 (en) * 2001-06-29 2001-08-22 Nycomed Amersham Plc Solid-phase nucleophilic fluorination

Also Published As

Publication number Publication date
KR20060052653A (ko) 2006-05-19
EP1560601A1 (de) 2005-08-10
ES2347535T3 (es) 2010-11-02
CN1694733A (zh) 2005-11-09
EP2229957A2 (de) 2010-09-22
EP1560601B1 (de) 2010-07-07
BR0215913A (pt) 2005-08-09
WO2004043497A1 (en) 2004-05-27
CN100478035C (zh) 2009-04-15
DE60236971D1 (de) 2010-08-19
JP2006505610A (ja) 2006-02-16
KR101001300B1 (ko) 2010-12-14
AU2002337926A1 (en) 2004-06-03
AU2002337926B2 (en) 2008-01-31
AU2002337926B8 (en) 2008-02-28
EP2229957A3 (de) 2010-10-06

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