ATE473294T1 - Verfahren und zusammensetzungen zur verwendung von mhc-klasse ii-invariante-kette-polypeptid als rezeptor für makrophagenwanderung-hemmfaktor - Google Patents

Verfahren und zusammensetzungen zur verwendung von mhc-klasse ii-invariante-kette-polypeptid als rezeptor für makrophagenwanderung-hemmfaktor

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Publication number
ATE473294T1
ATE473294T1 AT02725395T AT02725395T ATE473294T1 AT E473294 T1 ATE473294 T1 AT E473294T1 AT 02725395 T AT02725395 T AT 02725395T AT 02725395 T AT02725395 T AT 02725395T AT E473294 T1 ATE473294 T1 AT E473294T1
Authority
AT
Austria
Prior art keywords
compositions
chain polypeptide
inhibitory factor
invariant chain
macrophage migration
Prior art date
Application number
AT02725395T
Other languages
English (en)
Inventor
Richard Bucala
Seamas Donnelly
Lin Leng
Christine Metz
Robert Mitchell
Original Assignee
Cytokine Pharmasciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cytokine Pharmasciences Inc filed Critical Cytokine Pharmasciences Inc
Application granted granted Critical
Publication of ATE473294T1 publication Critical patent/ATE473294T1/de

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    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
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    • C07K—PEPTIDES
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    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
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AT02725395T 2001-03-29 2002-03-29 Verfahren und zusammensetzungen zur verwendung von mhc-klasse ii-invariante-kette-polypeptid als rezeptor für makrophagenwanderung-hemmfaktor ATE473294T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US27943501P 2001-03-29 2001-03-29
PCT/US2002/009580 WO2002079517A1 (en) 2001-03-29 2002-03-29 Methods and compositions for using mhc class ii invariant chain polypeptide as a receptor for macrophage migration inhibitory factor

Publications (1)

Publication Number Publication Date
ATE473294T1 true ATE473294T1 (de) 2010-07-15

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AT02725395T ATE473294T1 (de) 2001-03-29 2002-03-29 Verfahren und zusammensetzungen zur verwendung von mhc-klasse ii-invariante-kette-polypeptid als rezeptor für makrophagenwanderung-hemmfaktor

Country Status (10)

Country Link
US (10) US20030013122A1 (de)
EP (1) EP1383919B1 (de)
JP (1) JP4202763B2 (de)
AT (1) ATE473294T1 (de)
AU (1) AU2002255961B2 (de)
CA (1) CA2455915C (de)
DE (1) DE60236921D1 (de)
DK (1) DK1383919T3 (de)
ES (1) ES2352228T3 (de)
WO (1) WO2002079517A1 (de)

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CA2842195A1 (en) 2011-07-18 2013-01-24 Immunomedics, Inc. Fty720 increases cd74 expression and sensitizes cancer cells to anti-cd74 antibody-mediated cell death
AU2012320597C1 (en) 2011-10-07 2015-10-15 Baxalta GmbH oxMIF as a diagnostic marker
CN104994875B (zh) 2013-02-15 2018-10-09 免疫医疗公司 嵌合和人源化抗组蛋白抗体
WO2015051330A1 (en) 2013-10-03 2015-04-09 Oregon Health & Science University RECOMBINANT POLYPEPTIDES COMPRISING MHC CLASS II α1 DOMAINS
EP2944310B1 (de) 2014-05-16 2018-03-21 Mifcare MIF-Hemmer zur akuten oder chronischen Behandlung von pulmonaler Hypertonie
US10351621B2 (en) 2014-06-24 2019-07-16 Immunomedics, Inc. Anti-histone therapy in acute kidney injury
US9580495B2 (en) 2014-06-24 2017-02-28 Immunomedics, Inc. Anti-histone therapy for vascular necrosis in severe glomerulonephritis
WO2016057702A2 (en) 2014-10-07 2016-04-14 Cornell University Methods for prognosing and preventing metastatic liver disease
US10525101B2 (en) 2015-10-23 2020-01-07 Oregon Health & Science University Methods of treating inflammatory or autoimmune disorders with compounds that bind macrophage migration inhibitory factor
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ES2352228T3 (es) 2011-02-16
EP1383919B1 (de) 2010-07-07
US8779099B2 (en) 2014-07-15
JP2004532839A (ja) 2004-10-28
CA2455915C (en) 2013-05-14
US20180105593A1 (en) 2018-04-19
CA2455915A1 (en) 2002-10-10
US20120039914A1 (en) 2012-02-16
EP1383919A1 (de) 2004-01-28
US20110020321A1 (en) 2011-01-27
US9221903B2 (en) 2015-12-29
US20150010570A1 (en) 2015-01-08
EP1383919A4 (de) 2004-12-01
US20060024754A1 (en) 2006-02-02
US8617822B2 (en) 2013-12-31
WO2002079517A1 (en) 2002-10-10
DE60236921D1 (de) 2010-08-19
US7741057B2 (en) 2010-06-22
US20160152708A1 (en) 2016-06-02
US20140178403A1 (en) 2014-06-26
AU2002255961B2 (en) 2007-08-23
US20080146507A1 (en) 2008-06-19
US20030013122A1 (en) 2003-01-16
US20090263404A1 (en) 2009-10-22
DK1383919T3 (da) 2010-11-08
JP4202763B2 (ja) 2008-12-24

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