ATE473957T1 - Verfahren zur herstellung aromatischer derivate von 1-adamantan - Google Patents

Verfahren zur herstellung aromatischer derivate von 1-adamantan

Info

Publication number: ATE473957T1
Authority: AT; Austria
Prior art keywords: adamantane; obtaining; producing aromatic; precursor compound; aromatic derivatives
Prior art date: 2005-12-02

Application number

AT06832039T

Other languages

English (en)

Inventor

Alexander Comely

S Nchez Marta Marfil

Jane Llorenc Rafecas

Espaulella Xavier Verdaguer

Original Assignee

Finorga Sas

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2005-12-02

Filing date

2006-12-01

Publication date

2010-07-15

2006-12-01 Application filed by Finorga Sas filed Critical Finorga Sas

2010-07-15 Application granted granted Critical

2010-07-15 Publication of ATE473957T1 publication Critical patent/ATE473957T1/de

Links

238000004519 manufacturing process Methods 0.000 title 1
150000001875 compounds Chemical class 0.000 abstract 2
239000002243 precursor Substances 0.000 abstract 2
ZOXJGFHDIHLPTG-UHFFFAOYSA-N Boron Chemical compound [B] ZOXJGFHDIHLPTG-UHFFFAOYSA-N 0.000 abstract 1
FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
LZCDAPDGXCYOEH-UHFFFAOYSA-N adapalene Chemical compound C1=C(C(O)=O)C=CC2=CC(C3=CC=C(C(=C3)C34CC5CC(CC(C5)C3)C4)OC)=CC=C21 LZCDAPDGXCYOEH-UHFFFAOYSA-N 0.000 abstract 1
229960002916 adapalene Drugs 0.000 abstract 1
125000003118 aryl group Chemical group 0.000 abstract 1
229910052796 boron Inorganic materials 0.000 abstract 1
238000006473 carboxylation reaction Methods 0.000 abstract 1
230000008878 coupling Effects 0.000 abstract 1
238000010168 coupling process Methods 0.000 abstract 1
238000005859 coupling reaction Methods 0.000 abstract 1
DIOQZVSQGTUSAI-NJFSPNSNSA-N decane Chemical class CCCCCCCCC[14CH3] DIOQZVSQGTUSAI-NJFSPNSNSA-N 0.000 abstract 1
229910052749 magnesium Inorganic materials 0.000 abstract 1
239000011777 magnesium Substances 0.000 abstract 1
238000006263 metalation reaction Methods 0.000 abstract 1
238000000034 method Methods 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1
150000003751 zinc Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
- C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/15—Preparation of carboxylic acids or their salts, halides or anhydrides by reaction of organic compounds with carbon dioxide, e.g. Kolbe-Schmitt synthesis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/56—Ring systems containing bridged rings
- C07C2603/58—Ring systems containing bridged rings containing three rings
- C07C2603/70—Ring systems containing bridged rings containing three rings containing only six-membered rings
- C07C2603/74—Adamantanes

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Engineering & Computer Science (AREA)
Oil, Petroleum & Natural Gas (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AT06832039T 2005-12-02 2006-12-01 Verfahren zur herstellung aromatischer derivate von 1-adamantan ATE473957T1 (de)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
ES200503050		2005-12-02
PCT/IB2006/054547 WO2007063522A1 (en)	2005-12-02	2006-12-01	Process for the preparation of aromatic derivatives of 1-adamantane

Publications (1)

Publication Number	Publication Date
ATE473957T1 true ATE473957T1 (de)	2010-07-15

Family

ID=37908372

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AT06832039T ATE473957T1 (de)	2005-12-02	2006-12-01	Verfahren zur herstellung aromatischer derivate von 1-adamantan

Country Status (7)

Country	Link
US (2)	US7645910B2 (de)
EP (1)	EP1993986B1 (de)
JP (1)	JP2009517456A (de)
AT (1)	ATE473957T1 (de)
CA (1)	CA2631697A1 (de)
DE (1)	DE602006015535D1 (de)
WO (1)	WO2007063522A1 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
MX2009013332A (es)	2007-06-08	2010-01-25	Mannkind Corp	Inhibidores de ire-1 alfa.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
LU85849A1 (fr) *	1985-04-11	1986-11-05	Cird	Derives benzonaphtaleniques,leur procede de preparation et leur application dans les domaines pharmaceutiques et cosmetiques
TR199900684T2 (xx) *	1996-07-08	1999-07-21	Galderma Research & Development, S.N.C.	Apoptoz uyar�c� adamantil t�revleri ve bunlar�n kansere kar�� maddeler olarak kullan�m�.
ITMI20050550A1 (it) *	2005-04-01	2006-10-02	Dipharma Spa	Procedimento per la preparazione di adapalene
PL1868980T3 (pl) *	2005-04-08	2011-01-31	Galderma Res & Dev	Nowy sposób wytwarzania kwasu 6-[3-(1-adamantylo)-4-metoksyfenylo]-2-naftoesowego

2006
- 2006-12-01 AT AT06832039T patent/ATE473957T1/de not_active IP Right Cessation
- 2006-12-01 DE DE602006015535T patent/DE602006015535D1/de active Active
- 2006-12-01 EP EP06832039A patent/EP1993986B1/de not_active Not-in-force
- 2006-12-01 JP JP2008542929A patent/JP2009517456A/ja active Pending
- 2006-12-01 US US12/095,376 patent/US7645910B2/en not_active Expired - Fee Related
- 2006-12-01 CA CA002631697A patent/CA2631697A1/en not_active Abandoned
- 2006-12-01 WO PCT/IB2006/054547 patent/WO2007063522A1/en not_active Ceased
2009
- 2009-09-21 US US12/563,579 patent/US20100010265A1/en not_active Abandoned

Also Published As

Publication number	Publication date
EP1993986A1 (de)	2008-11-26
EP1993986B1 (de)	2010-07-14
US20090137841A1 (en)	2009-05-28
US7645910B2 (en)	2010-01-12
JP2009517456A (ja)	2009-04-30
WO2007063522A1 (en)	2007-06-07
US20100010265A1 (en)	2010-01-14
CA2631697A1 (en)	2007-06-07
DE602006015535D1 (de)	2010-08-26

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Legal Events

Date	Code	Title	Description
2011-01-15	RER	Ceased as to paragraph 5 lit. 3 law introducing patent treaties