ATE475707T1 - Polymorphismen im menschlichen gen für cytochrom p450 polypeptid cyp2c8 und deren verwendung in diagnose undtherapie - Google Patents

Polymorphismen im menschlichen gen für cytochrom p450 polypeptid cyp2c8 und deren verwendung in diagnose undtherapie

Info

Publication number
ATE475707T1
ATE475707T1 AT02776511T AT02776511T ATE475707T1 AT E475707 T1 ATE475707 T1 AT E475707T1 AT 02776511 T AT02776511 T AT 02776511T AT 02776511 T AT02776511 T AT 02776511T AT E475707 T1 ATE475707 T1 AT E475707T1
Authority
AT
Austria
Prior art keywords
relates
methods
polypeptide
polynucleotide
genes
Prior art date
Application number
AT02776511T
Other languages
English (en)
Inventor
Anja Penger
Reimund Sprenger
Ulrich Brinkmann
Original Assignee
Pgxhealth Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pgxhealth Llc filed Critical Pgxhealth Llc
Application granted granted Critical
Publication of ATE475707T1 publication Critical patent/ATE475707T1/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0071—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14)
    • C12N9/0077—Oxidoreductases (1.) acting on paired donors with incorporation of molecular oxygen (1.14) with a reduced iron-sulfur protein as one donor (1.14.15)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Immunology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
AT02776511T 2001-06-01 2002-05-31 Polymorphismen im menschlichen gen für cytochrom p450 polypeptid cyp2c8 und deren verwendung in diagnose undtherapie ATE475707T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP01112899 2001-06-01
PCT/EP2002/006000 WO2002099099A2 (en) 2001-06-01 2002-05-31 Polymorphisms in the human gene for cytochrome p450 polypeptide 2c8 and their use in diagnostic and therapeutic applications

Publications (1)

Publication Number Publication Date
ATE475707T1 true ATE475707T1 (de) 2010-08-15

Family

ID=8177562

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02776511T ATE475707T1 (de) 2001-06-01 2002-05-31 Polymorphismen im menschlichen gen für cytochrom p450 polypeptid cyp2c8 und deren verwendung in diagnose undtherapie

Country Status (7)

Country Link
US (2) US7871767B2 (de)
EP (2) EP2290055A3 (de)
AT (1) ATE475707T1 (de)
AU (1) AU2002344369A1 (de)
DE (1) DE60237154D1 (de)
ES (1) ES2349032T3 (de)
WO (1) WO2002099099A2 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE475707T1 (de) * 2001-06-01 2010-08-15 Pgxhealth Llc Polymorphismen im menschlichen gen für cytochrom p450 polypeptid cyp2c8 und deren verwendung in diagnose undtherapie
EP1456668B1 (de) * 2001-12-05 2007-05-02 Sense Proteomic Limited Protein arrays für allelvarianten und deren verwendung
GB0202018D0 (en) 2002-01-29 2002-03-13 Sense Proteomic Ltd Tag and method
US20040248323A1 (en) 2003-06-09 2004-12-09 Protometrix, Inc. Methods for conducting assays for enzyme activity on protein microarrays
WO2005045029A1 (ja) * 2003-11-05 2005-05-19 Japanese Foundation For Cancer Research パクリタキセル療法による副作用を予測する方法およびキット
CN114600803B (zh) * 2022-03-15 2023-05-09 北京协和建昊医药技术开发有限责任公司 一种斑马鱼cyp3a4代谢酶抑制模型、建立方法及应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5786191A (en) * 1992-04-09 1998-07-28 Goldstein; Joyce A. Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450 2C subfamily
US5403708A (en) * 1992-07-06 1995-04-04 Brennan; Thomas M. Methods and compositions for determining the sequence of nucleic acids
CA2363551A1 (en) * 1999-03-25 2000-10-05 Genset S.A. Biallelic markers related to genes involved in drug metabolism
US6673613B2 (en) 2000-07-26 2004-01-06 Cognis Corporation Use of CYP52A2A promoter to increase gene expression in yeast
ATE475707T1 (de) * 2001-06-01 2010-08-15 Pgxhealth Llc Polymorphismen im menschlichen gen für cytochrom p450 polypeptid cyp2c8 und deren verwendung in diagnose undtherapie

Also Published As

Publication number Publication date
EP2290055A3 (de) 2011-06-01
WO2002099099A3 (en) 2003-10-23
EP2290055A2 (de) 2011-03-02
EP1397486B1 (de) 2010-07-28
EP1397486A2 (de) 2004-03-17
US20110131671A1 (en) 2011-06-02
US20060172291A1 (en) 2006-08-03
AU2002344369A1 (en) 2002-12-16
WO2002099099A2 (en) 2002-12-12
US7871767B2 (en) 2011-01-18
ES2349032T3 (es) 2010-12-22
DE60237154D1 (de) 2010-09-09

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