ATE476195T1 - Zubereitungen von pro-insulin-c-peptid mit verzögerter freisetzung - Google Patents
Zubereitungen von pro-insulin-c-peptid mit verzögerter freisetzungInfo
- Publication number
- ATE476195T1 ATE476195T1 AT06744056T AT06744056T ATE476195T1 AT E476195 T1 ATE476195 T1 AT E476195T1 AT 06744056 T AT06744056 T AT 06744056T AT 06744056 T AT06744056 T AT 06744056T AT E476195 T1 ATE476195 T1 AT E476195T1
- Authority
- AT
- Austria
- Prior art keywords
- composition
- peptide
- insulin
- pro
- gel
- Prior art date
Links
- VOUAQYXWVJDEQY-QENPJCQMSA-N 33017-11-7 Chemical compound OC(=O)CC[C@H](N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)NCC(=O)NCC(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N1[C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(O)=O)C(=O)NCC(=O)N[C@@H](CO)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(N)=O)C(O)=O)CCC1 VOUAQYXWVJDEQY-QENPJCQMSA-N 0.000 title abstract 3
- 108010075254 C-Peptide Proteins 0.000 title abstract 3
- 238000002360 preparation method Methods 0.000 title abstract 2
- 230000003111 delayed effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 abstract 6
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 229910021645 metal ion Inorganic materials 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 238000013268 sustained release Methods 0.000 abstract 1
- 239000012730 sustained-release form Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Biomedical Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Obesity (AREA)
- Organic Chemistry (AREA)
- Emergency Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0511269.3A GB0511269D0 (en) | 2005-06-02 | 2005-06-02 | Sustained release preparation of pro-insulin C-peptide |
| PCT/GB2006/001997 WO2006129095A2 (en) | 2005-06-02 | 2006-06-02 | Sustained release preparations of pro-insulin c-peptide |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE476195T1 true ATE476195T1 (de) | 2010-08-15 |
Family
ID=34835031
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06744056T ATE476195T1 (de) | 2005-06-02 | 2006-06-02 | Zubereitungen von pro-insulin-c-peptid mit verzögerter freisetzung |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US8927489B2 (de) |
| EP (1) | EP1912669B1 (de) |
| AT (1) | ATE476195T1 (de) |
| DE (1) | DE602006015968D1 (de) |
| GB (1) | GB0511269D0 (de) |
| WO (1) | WO2006129095A2 (de) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0511269D0 (en) | 2005-06-02 | 2005-07-13 | Creative Peptides Sweden Ab | Sustained release preparation of pro-insulin C-peptide |
| WO2008118390A2 (en) * | 2007-03-23 | 2008-10-02 | Wayne State University | Biomarkers for diagnostic and therapeutic methods |
| WO2008118387A2 (en) * | 2007-03-23 | 2008-10-02 | Wayne State University | Erythrocyte atp-release modulators |
| WO2011081915A2 (en) * | 2009-12-15 | 2011-07-07 | Cebix Inc. | Methods for treating erectile dysfunction in patients with insulin-dependent diabetes |
| CA2798518A1 (en) | 2010-05-17 | 2011-11-24 | Cebix, Inc. | Pegylated c-peptide |
| ES2673672T3 (es) | 2011-02-11 | 2018-06-25 | The Regents Of The University Of Michigan | Composiciones tripeptídicas y su uso para el tratamiento de la diabetes |
Family Cites Families (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2143590A (en) | 1936-09-26 | 1939-01-10 | Univ Alberta | Insulin preparation and process of producing crystals of insulin |
| US2882203A (en) | 1951-06-26 | 1959-04-14 | Novo Terapeutisk Labor As | Injectable insulin preparation with protracted effect |
| NL289055A (de) | 1963-02-15 | |||
| US3852422A (en) | 1971-06-26 | 1974-12-03 | Serono Ist Farm | Long-active gonadotropins |
| BE795516A (fr) * | 1972-02-17 | 1973-08-16 | Ciba Geigy | Preparations de peptides huileuses et injectables et procede pour leur preparation |
| CH650679A5 (de) | 1981-08-27 | 1985-08-15 | Lilly Co Eli | Gegen diabetes mellitus wirksames pharmazeutisches mittel. |
| HU196714B (en) | 1984-10-04 | 1989-01-30 | Monsanto Co | Process for producing non-aqueous composition comprising somatotropin |
| GB9108634D0 (en) | 1991-04-23 | 1991-06-12 | Ciba Geigy | Pharmaceutical compositions |
| NZ250844A (en) | 1993-04-07 | 1996-03-26 | Pfizer | Treatment of non-insulin dependant diabetes with peptides; composition |
| WO1995021622A1 (en) | 1994-02-09 | 1995-08-17 | Brigham & Women's Hospital | Gel-forming polypeptide derivatives |
| US5595760A (en) | 1994-09-02 | 1997-01-21 | Delab | Sustained release of peptides from pharmaceutical compositions |
| EP0796106B1 (de) | 1994-12-23 | 2003-03-19 | Novo Nordisk A/S | Glp-1 zusammensetzungen mit verlängerter wirkdauer |
| US20010007673A1 (en) * | 1999-11-12 | 2001-07-12 | Merrill Seymour Goldenberg | Sustained-release delayed gels |
| FR2776520B1 (fr) | 1998-03-25 | 2000-05-05 | Sod Conseils Rech Applic | Nouvelles compositions pharmaceutiques destinees a la liberation prolongee de peptides et leur procede de preparation |
| DE10041478A1 (de) * | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| DE10055857A1 (de) * | 2000-11-10 | 2002-08-22 | Creative Peptides Sweden Ab Dj | Neue pharmazeutische Depotformulierung |
| GB0117057D0 (en) | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| US7098305B2 (en) | 2001-09-06 | 2006-08-29 | Ardana Bioscience Limited | Sustained release of microcrystalline peptide suspensions |
| ATE432689T1 (de) | 2002-03-04 | 2009-06-15 | Ipsen Pharma | Arzneimittelformulierungen mit verzögerter freisetzung mit einem trägerpeptid |
| GB0218970D0 (en) | 2002-08-14 | 2002-09-25 | Creative Peptides Sweden Ab | Fragments of Insulin c-peptide |
| US7884185B2 (en) * | 2004-07-28 | 2011-02-08 | University Of Delaware | Hydrogels and uses thereof |
| US20060046962A1 (en) * | 2004-08-25 | 2006-03-02 | Aegis Therapeutics Llc | Absorption enhancers for drug administration |
| GB0511269D0 (en) | 2005-06-02 | 2005-07-13 | Creative Peptides Sweden Ab | Sustained release preparation of pro-insulin C-peptide |
| CA2798518A1 (en) * | 2010-05-17 | 2011-11-24 | Cebix, Inc. | Pegylated c-peptide |
-
2005
- 2005-06-02 GB GBGB0511269.3A patent/GB0511269D0/en not_active Ceased
-
2006
- 2006-06-02 AT AT06744056T patent/ATE476195T1/de not_active IP Right Cessation
- 2006-06-02 US US11/916,116 patent/US8927489B2/en not_active Expired - Fee Related
- 2006-06-02 EP EP06744056A patent/EP1912669B1/de not_active Not-in-force
- 2006-06-02 DE DE602006015968T patent/DE602006015968D1/de active Active
- 2006-06-02 WO PCT/GB2006/001997 patent/WO2006129095A2/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| US20090170761A1 (en) | 2009-07-02 |
| WO2006129095A3 (en) | 2007-05-10 |
| DE602006015968D1 (de) | 2010-09-16 |
| US8927489B2 (en) | 2015-01-06 |
| WO2006129095A2 (en) | 2006-12-07 |
| EP1912669A2 (de) | 2008-04-23 |
| GB0511269D0 (en) | 2005-07-13 |
| EP1912669B1 (de) | 2010-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |