ATE476439T1 - Amplifikationsblocker umfassend interkalierende nukleinsäuren (ina) enthaltend interkalierende pseudonukleotide (ipn) - Google Patents

Amplifikationsblocker umfassend interkalierende nukleinsäuren (ina) enthaltend interkalierende pseudonukleotide (ipn)

Info

Publication number
ATE476439T1
ATE476439T1 AT05779000T AT05779000T ATE476439T1 AT E476439 T1 ATE476439 T1 AT E476439T1 AT 05779000 T AT05779000 T AT 05779000T AT 05779000 T AT05779000 T AT 05779000T AT E476439 T1 ATE476439 T1 AT E476439T1
Authority
AT
Austria
Prior art keywords
intercalating
ina
ipn
nucleic acids
pseudonucleotides
Prior art date
Application number
AT05779000T
Other languages
English (en)
Inventor
Douglas Millar
Original Assignee
Human Genetic Signatures Pty
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2004905213A external-priority patent/AU2004905213A0/en
Application filed by Human Genetic Signatures Pty filed Critical Human Genetic Signatures Pty
Application granted granted Critical
Publication of ATE476439T1 publication Critical patent/ATE476439T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844Nucleic acid amplification reactions
    • C12Q1/686Polymerase chain reaction [PCR]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT05779000T 2004-09-10 2005-09-09 Amplifikationsblocker umfassend interkalierende nukleinsäuren (ina) enthaltend interkalierende pseudonukleotide (ipn) ATE476439T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2004905213A AU2004905213A0 (en) 2004-09-10 Amplification Blocker
PCT/AU2005/001374 WO2006026828A1 (en) 2004-09-10 2005-09-09 Amplification blocker comprising intercalating nucleic acids (tna) containing intercalating pseudonucleotides (ipn)

Publications (1)

Publication Number Publication Date
ATE476439T1 true ATE476439T1 (de) 2010-08-15

Family

ID=36036025

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05779000T ATE476439T1 (de) 2004-09-10 2005-09-09 Amplifikationsblocker umfassend interkalierende nukleinsäuren (ina) enthaltend interkalierende pseudonukleotide (ipn)

Country Status (9)

Country Link
US (1) US7803580B2 (de)
EP (1) EP1794173B1 (de)
JP (1) JP4980219B2 (de)
CN (1) CN101056883B (de)
AT (1) ATE476439T1 (de)
CA (1) CA2580145C (de)
DE (1) DE602005022740D1 (de)
DK (1) DK1794173T3 (de)
WO (1) WO2006026828A1 (de)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004028478D1 (de) * 2003-06-17 2010-09-16 Human Genetic Signatures Pty Verfahren zur genomamplifikation
CN1863927B (zh) * 2003-09-04 2010-08-11 人类遗传标记控股有限公司 核酸检测分析
US8168777B2 (en) 2004-04-29 2012-05-01 Human Genetic Signatures Pty. Ltd. Bisulphite reagent treatment of nucleic acid
US7833942B2 (en) * 2004-12-03 2010-11-16 Human Genetic Signatures Pty. Ltd. Methods for simplifying microbial nucleic acids by chemical modification of cytosines
US20090029346A1 (en) * 2004-12-23 2009-01-29 Human Genetic Signatures Pty., Ltd. Detection of human papilloma virus
JP2008541705A (ja) * 2005-05-26 2008-11-27 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド 非標準塩基を含むプライマーを使用する等温鎖置換増幅
WO2007030882A1 (en) * 2005-09-14 2007-03-22 Human Genetic Signatures Pty Ltd Assay for a health state
US20080050738A1 (en) * 2006-05-31 2008-02-28 Human Genetic Signatures Pty Ltd. Detection of target nucleic acid
US20100092972A1 (en) * 2007-03-16 2010-04-15 Human Genetic Signatures Pty Ltd. Assay for gene expression
US8071338B2 (en) 2007-08-08 2011-12-06 Roche Molecular Systems, Inc. Suppression of amplification using an oligonucleotide and a polymerase significantly lacking 5′-3′ nuclease activity
CN101918595A (zh) * 2007-11-27 2010-12-15 人类遗传标记控股有限公司 用于扩增和复制亚硫酸氢盐修饰的核酸的酶
CN101883747A (zh) * 2007-12-05 2010-11-10 人类遗传标记控股有限公司 Rna的亚硫酸氢盐处理
US9879222B2 (en) 2007-12-14 2018-01-30 Mofa Group Llc Gender-specific separation of sperm cells and embryos
US20110003700A1 (en) * 2007-12-20 2011-01-06 Human Genetic Signatures Pty Ltd. Elimination of contaminants associated with nucleic acid amplification
US20090215050A1 (en) * 2008-02-22 2009-08-27 Robert Delmar Jenison Systems and methods for point-of-care amplification and detection of polynucleotides
CA2719795A1 (en) * 2008-03-27 2009-10-01 Greene, Tweed Of Delaware, Inc. Inert substrate-bonded fluoroelastomer components and related methods
FR2940805B1 (fr) * 2009-01-05 2015-10-16 Biomerieux Sa Procede d'amplification et/ou de detection d'acides nucleiques, kits et utilisations de ce procede
WO2011032034A2 (en) 2009-09-10 2011-03-17 University Of Idaho Nucleobase-functionalized conformationally restricted nucleotides and oligonucleotides for targeting nucleic acids
US8835358B2 (en) 2009-12-15 2014-09-16 Cellular Research, Inc. Digital counting of individual molecules by stochastic attachment of diverse labels
MX2012012908A (es) * 2010-05-07 2013-05-01 Quantibact As Metodo para generar un acido nucleico de doble hebra con una saliente de una sola hebra.
RU2014106024A (ru) 2011-07-19 2015-08-27 Юниверсити Оф Айдахо Варианты осуществления зонда и способы направленного действия на нуклеиновые кислоты
BR112014005253B1 (pt) 2011-09-07 2019-11-05 Human Genetic Signatures Pty Ltd método de detecção molecular
ES2904816T3 (es) 2012-02-27 2022-04-06 Becton Dickinson Co Composiciones para recuento molecular
EP3480321B8 (de) 2013-08-28 2021-03-10 Becton, Dickinson and Company Massiv parallele einzelzellanalyse
ES2836802T3 (es) 2015-02-27 2021-06-28 Becton Dickinson Co Códigos de barras moleculares espacialmente direccionables
EP4180535A1 (de) 2015-03-30 2023-05-17 Becton, Dickinson and Company Verfahren und zusammensetzungen für kombinatorische barcodierung
JP6940484B2 (ja) 2015-09-11 2021-09-29 セルラー リサーチ, インコーポレイテッド ライブラリー正規化のための方法および組成物
US10301677B2 (en) 2016-05-25 2019-05-28 Cellular Research, Inc. Normalization of nucleic acid libraries
US10202641B2 (en) 2016-05-31 2019-02-12 Cellular Research, Inc. Error correction in amplification of samples
US10640763B2 (en) 2016-05-31 2020-05-05 Cellular Research, Inc. Molecular indexing of internal sequences
CN109791157B (zh) 2016-09-26 2022-06-07 贝克顿迪金森公司 使用具有条形码化的寡核苷酸序列的试剂测量蛋白质表达
CN107012221A (zh) * 2016-10-14 2017-08-04 苏州艾达康医疗科技有限公司 基于阻断物的富集系统及其应用
CN110382708A (zh) 2017-02-01 2019-10-25 赛卢拉研究公司 使用阻断性寡核苷酸进行选择性扩增
KR102790050B1 (ko) 2017-06-05 2025-04-04 백톤 디킨슨 앤드 컴퍼니 단일 세포를 위한 샘플 인덱싱
US11773441B2 (en) 2018-05-03 2023-10-03 Becton, Dickinson And Company High throughput multiomics sample analysis
EP3788170B1 (de) 2018-05-03 2025-01-01 Becton, Dickinson and Company Molekulare barcodierung auf gegenüberliegenden transkriptenden
US11639517B2 (en) 2018-10-01 2023-05-02 Becton, Dickinson And Company Determining 5′ transcript sequences
EP3877520B1 (de) 2018-11-08 2025-03-19 Becton, Dickson And Company Ganze transkriptomanalyse von einzelzellen mittels random-priming
US11492660B2 (en) 2018-12-13 2022-11-08 Becton, Dickinson And Company Selective extension in single cell whole transcriptome analysis
US11661631B2 (en) 2019-01-23 2023-05-30 Becton, Dickinson And Company Oligonucleotides associated with antibodies
US12071617B2 (en) 2019-02-14 2024-08-27 Becton, Dickinson And Company Hybrid targeted and whole transcriptome amplification
CN110004219A (zh) * 2019-04-19 2019-07-12 格尚微(上海)生物科技有限公司 一种egfr t790m和c797s顺式突变的检测方法
EP4707405A2 (de) 2019-07-22 2026-03-11 Becton, Dickinson and Company Einzelzellchromatin-immunpräzipitations-sequenzierungs-assay
EP4055160B1 (de) 2019-11-08 2024-04-10 Becton Dickinson and Company Verwendung von random-rpiming zur gewinnung von v(d)j-informationen in voller länge für immunrepertoiresequenzierung
WO2021146207A1 (en) 2020-01-13 2021-07-22 Becton, Dickinson And Company Methods and compositions for quantitation of proteins and rna
EP4097228B1 (de) 2020-01-29 2024-08-14 Becton, Dickinson and Company Barkodierte wells zur räumlichen abbildung einzelner zellen durch sequenzierung
WO2021173719A1 (en) 2020-02-25 2021-09-02 Becton, Dickinson And Company Bi-specific probes to enable the use of single-cell samples as single color compensation control
WO2021231779A1 (en) 2020-05-14 2021-11-18 Becton, Dickinson And Company Primers for immune repertoire profiling
ES2987035T3 (es) 2020-06-02 2024-11-13 Becton Dickinson Co Oligonucleótidos y perlas para el ensayo de expresión génica principal 5
US11932901B2 (en) 2020-07-13 2024-03-19 Becton, Dickinson And Company Target enrichment using nucleic acid probes for scRNAseq
WO2022026909A1 (en) 2020-07-31 2022-02-03 Becton, Dickinson And Company Single cell assay for transposase-accessible chromatin
WO2022029159A1 (en) * 2020-08-04 2022-02-10 Theraxen S.A. Xeno-nucleotide based branched dna assay for the detection of nucleic acids
US11739443B2 (en) 2020-11-20 2023-08-29 Becton, Dickinson And Company Profiling of highly expressed and lowly expressed proteins
US12392771B2 (en) 2020-12-15 2025-08-19 Becton, Dickinson And Company Single cell secretome analysis

Family Cites Families (60)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5750338A (en) * 1986-10-23 1998-05-12 Amoco Corporation Target and background capture methods with amplification for affinity assays
DE69327454T2 (de) * 1992-10-09 2000-05-11 Vysis, Inc. Analytisches verfahren
US5473060A (en) 1993-07-02 1995-12-05 Lynx Therapeutics, Inc. Oligonucleotide clamps having diagnostic applications
EP0754240B1 (de) * 1994-02-07 2003-08-20 Beckman Coulter, Inc. Ligase/polymerase-vermittelte analyse genetischer elemente von einzelnukleotid-polymorphismen und ihre verwendung in der genetischen analyse
SE9400522D0 (sv) 1994-02-16 1994-02-16 Ulf Landegren Method and reagent for detecting specific nucleotide sequences
FR2737223B1 (fr) * 1995-07-24 1997-09-12 Bio Merieux Procede d'amplification de sequences d'acide nucleique par deplacement, a l'aide d'amorces chimeres
US5994066A (en) 1995-09-11 1999-11-30 Infectio Diagnostic, Inc. Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
SE9601676D0 (sv) 1996-04-30 1996-04-30 Ulf Landegren Improved probing of specific mucleic acids
EP1736554B1 (de) 1996-05-29 2013-10-09 Cornell Research Foundation, Inc. Bestimmung von Unterschieden in der Nukleinsäuresequenz mittels einer Kombination von Ligasebestimmung und Polymerasekettenreaktion
US6017704A (en) * 1996-06-03 2000-01-25 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
US5786146A (en) * 1996-06-03 1998-07-28 The Johns Hopkins University School Of Medicine Method of detection of methylated nucleic acid using agents which modify unmethylated cytosine and distinguishing modified methylated and non-methylated nucleic acids
CA2276306C (en) 1996-12-30 2009-12-15 The Johns Hopkins University School Of Medicine Loss of imprinting-based in vitro diagnostic method to determine the propensity to develop cancer
EP2341057A3 (de) 1997-09-12 2011-11-23 Exiqon A/S Oligonukleotidanaloga
GB9806253D0 (en) 1998-03-25 1998-05-20 Tepnel Medical Ltd Amplification of nucleic acids
DE19905082C1 (de) 1999-01-29 2000-05-18 Epigenomics Gmbh Verfahren zur Identifikation von Cytosin-Methylierungsmustern in genomischen DNA-Proben
US6410231B1 (en) 1999-02-26 2002-06-25 Incyte Genomics, Inc. SNP detection
US6951722B2 (en) * 1999-03-19 2005-10-04 Takara Bio Inc. Method for amplifying nucleic acid sequence
US6331393B1 (en) * 1999-05-14 2001-12-18 University Of Southern California Process for high-throughput DNA methylation analysis
DE19935749C2 (de) 1999-07-28 2003-06-26 Epigenomics Ag Verfahren zur Chrakterisierung von Nukleinsäurefragmenten
US6692918B2 (en) * 1999-09-13 2004-02-17 Nugen Technologies, Inc. Methods and compositions for linear isothermal amplification of polynucleotide sequences
AU776421B2 (en) * 1999-11-12 2004-09-09 Epigenomics Ag Method for the controlled implementation of complex PCR amplifications
DE19957827C2 (de) 1999-11-25 2003-06-12 Epigenomics Ag Verwendung eines Oligomer-Arrays mit PNA- und/oder DNA-Oligomeren auf einer Oberfläche
DE19959691A1 (de) 1999-12-06 2001-08-16 Epigenomics Ag Verfahren zur parallelen Detektions des Methylierungszustandes von genomischer DNA
EP1130113A1 (de) 2000-02-15 2001-09-05 Johannes Petrus Schouten Amplifizierungsassay abhängig von multiplex Ligation
DE10010281B4 (de) * 2000-02-25 2005-03-10 Epigenomics Ag Ligase/Polymerase-Verfahren zur Detektion von Cytosin-Methylierung in DNA Proben
US20050282157A1 (en) 2000-04-06 2005-12-22 Alexander Olek Diagnosis of diseases associated with dna replication
AUPR142500A0 (en) * 2000-11-13 2000-12-07 Human Genetic Signatures Pty Ltd A peptide nucleic acid-based assay for the detection of specific nucleic acid sequences
DE10061348C2 (de) * 2000-12-06 2002-10-24 Epigenomics Ag Verfahren zur Quantifizierung von Cytosin-Methylierungen in komplex amplifizierter genomischer DNA
US20020142397A1 (en) * 2000-12-22 2002-10-03 Philippe Collas Methods for altering cell fate
KR20030071854A (ko) * 2001-02-06 2003-09-06 다카라 바이오 가부시키가이샤 증폭 핵산 및 그의 고정화물
DE10112515B4 (de) * 2001-03-09 2004-02-12 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungsmustern mit hoher Sensitivität
GB0113118D0 (en) 2001-05-31 2001-07-18 Intercytex Ltd Stem Cells
CA2492007A1 (en) 2001-07-15 2003-01-30 Keck Graduate Institute Amplification of nucleic acid fragments using nicking agents
WO2003016569A1 (en) * 2001-08-20 2003-02-27 Takara Bio Inc. Nucleic acid amplification methods
EP1461458A4 (de) 2001-12-03 2005-10-26 Illumina Inc Multiplex-methylierungsnachweisverfahren
EP1319718A1 (de) 2001-12-14 2003-06-18 Keygene N.V. Hochdurchsatzanalyse und Detektion von mehreren Zielsequenzen
US20060014144A1 (en) * 2001-12-18 2006-01-19 Christensen Ulf B Pseudonucleotide comprising an intercalator
AU2002358463A1 (en) 2001-12-18 2003-06-30 Human Genetic Signatures Pty Ltd Oligonucleotide analogues comprising intercalator pseudonucleotides
US7932070B2 (en) * 2001-12-21 2011-04-26 Agilent Technologies, Inc. High fidelity DNA polymerase compositions and uses therefor
US6960436B2 (en) * 2002-02-06 2005-11-01 Epigenomics Ag Quantitative methylation detection in DNA samples
DE10236406C1 (de) 2002-08-02 2003-12-24 Epigenomics Ag Verfahren zur Amplifikation von Nukleinsäuren mit geringer Komplexität
SE0202867D0 (sv) * 2002-09-27 2002-09-27 Pyrosequencing Ab New sequencing method
AU2002951899A0 (en) * 2002-10-04 2002-10-24 Macquarie University Random drift mutagenesis
AU2003900368A0 (en) * 2003-01-24 2003-02-13 Human Genetic Signatures Pty Ltd Assay for nucleic acid molecules
US20040203004A1 (en) 2003-04-10 2004-10-14 Bernard Hans Ulrich Diagnostic apparatus and method
AU2003901834A0 (en) * 2003-04-17 2003-05-01 Clearcoll Pty Ltd Cross-linked polysaccharide compositions
US7288373B2 (en) 2003-05-02 2007-10-30 Human Genetic Signatures Pty Ltd. Treatment of methylated nucleic acid
DE602004028478D1 (de) * 2003-06-17 2010-09-16 Human Genetic Signatures Pty Verfahren zur genomamplifikation
DE10331107B3 (de) * 2003-07-04 2004-12-02 Epigenomics Ag Verfahren zum Nachweis von Cytosin-Methylierungen in DNA mittels Cytidin-Deaminasen
US7368239B2 (en) 2003-08-29 2008-05-06 Applera Corporation Method and materials for polyamine catalyzed bisulfite conversion of cytosine to uracil
CN1863927B (zh) * 2003-09-04 2010-08-11 人类遗传标记控股有限公司 核酸检测分析
US7501240B2 (en) * 2003-12-02 2009-03-10 Roche Molecular Systems, Inc. Method for bisulfite treatment
CN1890368A (zh) 2003-12-10 2007-01-03 宝生物工程株式会社 扩增核酸的方法
EP2380993B1 (de) * 2004-03-08 2015-12-23 Rubicon Genomics, Inc. Verfahren zur Erstellung und Erweiterung von DNA-Bibliotheken zur sensitiven Erkennung und Analyse von DNA-Methylierung
US8168777B2 (en) * 2004-04-29 2012-05-01 Human Genetic Signatures Pty. Ltd. Bisulphite reagent treatment of nucleic acid
US7361465B2 (en) * 2004-09-07 2008-04-22 Applera Corporation Methods and compositions for tailing and amplifying RNA
US7833942B2 (en) * 2004-12-03 2010-11-16 Human Genetic Signatures Pty. Ltd. Methods for simplifying microbial nucleic acids by chemical modification of cytosines
US20090029346A1 (en) * 2004-12-23 2009-01-29 Human Genetic Signatures Pty., Ltd. Detection of human papilloma virus
ES2546848T3 (es) * 2006-03-10 2015-09-29 Epigenomics Ag Un método para identificar una muestra biológica para el análisis de la metilación
US20080050738A1 (en) * 2006-05-31 2008-02-28 Human Genetic Signatures Pty Ltd. Detection of target nucleic acid

Also Published As

Publication number Publication date
JP2008512101A (ja) 2008-04-24
DE602005022740D1 (de) 2010-09-16
EP1794173A4 (de) 2009-01-07
EP1794173B1 (de) 2010-08-04
JP4980219B2 (ja) 2012-07-18
DK1794173T3 (da) 2010-10-25
EP1794173A1 (de) 2007-06-13
CN101056883B (zh) 2012-10-10
WO2006026828A1 (en) 2006-03-16
CA2580145C (en) 2014-10-28
US20090130657A1 (en) 2009-05-21
CA2580145A1 (en) 2006-03-16
CN101056883A (zh) 2007-10-17
US7803580B2 (en) 2010-09-28

Similar Documents

Publication Publication Date Title
ATE476439T1 (de) Amplifikationsblocker umfassend interkalierende nukleinsäuren (ina) enthaltend interkalierende pseudonukleotide (ipn)
MX2007005408A (es) Compuestos de aminoquinazolinas.
DK1768490T3 (da) Systemer og fremgangsmåder til ex-vivo-organpleje
ATE368651T1 (de) Pyridazinon-derivate als gsk-3beta-hemmer
DE602007005016D1 (de) 2-octyl-(meth)acrylat-haftzusammensetzung
GB2436983A (en) Information access with usage-driven metadata feedback
DK1230375T3 (da) Inhibering af genekspression med dsRNA
NO20071127L (no) Triazoloftalaziner
ATE289598T1 (de) Glutamin-thiazolidide und -pyrrolidide sowie ihre verwendung als dipeptidylpeptidase iv inhibitoren
ATE412649T1 (de) Substituierte heteroarylbenzofuransäuren
EA200701396A1 (ru) Триазолофталазины в качестве ингибиторов pde-2
DK1562444T3 (da) Fremgangsmåde til formindskelse af acrylamidindholdet i varmebehandlede levnedsmidler
NL1029240A1 (nl) Hoog-vermogen geschakelde versterker met hoge betrouwbaarheid.
EA200802357A1 (ru) Обработка скважин
EA201000494A1 (ru) Новые гидрокси-8-гетероарилфенантридины и их применение в качестве ингибиторов pde4
DE60316984D1 (de) Benzoylsulfonamide als antitumor-mittel
WO2006072612A3 (en) Triazolophthalazines as pde2- inhibitors
SE0103710D0 (sv) Compounds
TW200635587A (en) Inducible nitric oxide synthase dimerization inhibitors
DE602006020608D1 (de) Haftklebemittel
DK1540335T3 (da) Screeningsfremgangsmåder til kognitive forstækere
TW200708929A (en) Opposite-phase scheme for peak current reduction
ATE480542T1 (de) Pyrroloä1,2-düä1,2-4ütriazin als inhibitoren von c-jun-n-terminal-kinasen (jnk) und p-38-kinasen
MX2007002917A (es) Todo-trans-retinol: todo-trans-13, 14-dihidrorretinol saturasa y metodos de uso de la misma.
NO20061316L (no) Imidazopyndinderivater som induserbare NO-syntaseinhibitorer

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties